1. Oregon Health & Science University

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    1. Mentioned In 452 Articles

    2. Total retinal blood flow measurement with ultrahigh speed swept source/Fourier domain OCT

      Total retinal blood flow measurement with ultrahigh speed swept source/Fourier domain OCT
      Doppler OCT provides depth-resolved information on flow in biological tissues. In this article, we demonstrate ultrahigh speed swept source/Fourier domain OCT for visualization and quantitative assessment of retinal blood flow. Using swept laser technology, the system operated in the 1050-nm wavelength range at a high axial scan rate of 200 kHz. The rapid imaging speed not only enables volumetric imaging with high axial scan densities, but also enables measurement ...
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    3. OPN Talks with Dr. James Fujimoto - OCT Pioneer and CLEO:2011 Plenary Speaker

      OPN Talks with Dr. James Fujimoto - OCT Pioneer and CLEO:2011 Plenary Speaker
      Optical coherence tomography (OCT) is a relatively new technology, but is it having a significant impact in biomedical research. It was first demonstrated just 20 years ago, and it has already emerged as a powerful imaging tool in the biomedical world. In fact, OCT has become so widespread in the medical field that a journal keyword search on "optical coherence tomography" retrieves more than 10,000 references. The commercial market ...
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    4. Feature Of The Week 4/24/11: In vivo 3D imaging of intra-cochlear microstructures and microvascular perfusion in mice with ultra-high sensitive optical micro-angiography (UHS-OMAG)

      Feature Of The Week 4/24/11: In vivo 3D imaging of intra-cochlear microstructures and microvascular perfusion in mice with ultra-high sensitive optical micro-angiography (UHS-OMAG)
      ...54   Researchers from the Biophotonics and Imaging Laboratory (BAIL) at Oregon Health & Science University (OHSU) have recently pioneered a novel ultra-high sensitive volumetric perfusion imaging modality based on opti...
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    5. Basic characteristics of interference image obtained using spatially phase-modulated mirror array

      Basic characteristics of interference image obtained using spatially phase-modulated mirror array
      Abstract  Single-shot full-field optical coherence tomography (OCT) using spatially phase-modulated reference light has been proposed to achieve a higher sensitivity.16) The reference light can be generated by a spatially phase-modulated mirror array (SPMA). The basic characteristics of an interference image using SPMA have been demonstrated using a superluminescent diode (SLD) with a center wavelength of 840 nm as a popular low-coherence light source. SPMA consisted of a small mirror ...
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    6. Video of Dr. David Huang MD PhD from OHSU talking about New Developments in Optical Coherence Tomography for Ophthalmology

      Video of Dr. David Huang MD PhD from OHSU talking about New Developments in Optical Coherence Tomography for Ophthalmology
      ...g click HERE or go to his research group website HERE. Dr. David Huang is a professor of ophthalmology at the Oregon Health & Science University Casey Eye Institute and also one of the pioneers in the field of OCT and th...
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    7. Dermal reflectivity determined by optical coherence tomography is an indicator of epidermal hyperplasia and dermal edema within inflamed skin

      Dermal reflectivity determined by optical coherence tomography is an indicator of epidermal hyperplasia and dermal edema within inflamed skin
      ...egon Health and Science University, Department of Dermatology, 3303 S. W. Bond Avenue, Portland, Oregon 97239 Oregon Health and Science University, Department of Biomedical Engineering, 3303 S. W. Bond Avenue, Portland, ...
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    8. Highly sensitive imaging of renal microcirculation in vivo using ultrahigh sensitive optical microangiography

      Highly sensitive imaging of renal microcirculation in vivo using ultrahigh sensitive optical microangiography
      Studying renal microcirculation and its dynamics is of great importance for understanding the renal function and further aiding the diagnosis, prevention and treatment of renal pathologies. In this paper, we present a potentially useful method to provide high-sensitive volumetric imaging of renal microcirculations using ultrahigh-sensitive optical microangiography (UHS-OMAG). The UHS-OMAG image system used here is based on spectral domain optical coherence tomography, which uses a broadband light source centered at ...
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    9. Repeatability of laser in situ keratomileusis flap thickness measurement by Fourier-domain optical coherence tomography

      Repeatability of laser in situ keratomileusis flap thickness measurement by Fourier-domain optical coherence tomography
      Purpose: To evaluate the repeatability of Fourier-domain optical coherence tomography (OCT) measurements of the thickness of femtosecond laser–created laser in situ keratomileusis (LASIK) flaps.Setting: Doheny Eye Institute, University of Southern California, Los Angeles, California, USA.Design: Case series, evaluation of diagnostic technology.Methods: In this consecutive series, Fourier-domain OCT (RTVue) was used to measure flap thickness 1 week after LASIK. Flaps were created with a Pulsion 60 kHz ...
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    10. Dual angle scan protocol with Doppler optical coherence tomography for retinal blood flow measurement

      Dual angle scan protocol with Doppler optical coherence tomography for retinal blood flow measurement
      To improve the scan quality of Doppler Optical coherence tomography for blood flow measurement, we investigate how to improve the Doppler signal for all vessels around optic disc. Doppler signal is depending on the Doppler angle, which is defined as angle between OCT beams and normal direction vessel. In this examination, we test the effect of different OCT beam direction on Doppler angles of all veins. We also test maximizing ...
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    11. Normal and keratoconic corneal epithelial thickness mapping using Fourier-domain optical coherence tomography

      Normal and keratoconic corneal epithelial thickness mapping using Fourier-domain optical coherence tomography
      The detection of early-stage keratoconus is one of the most important safety issues in screening candidates for corneal refractive surgeries. We propose to use epithelial thickness maps to assist the diagnosis of keratoconus. The corneal epithelial thickness in normal and keratoconic eyes was mapped with optical coherence tomography (OCT). A Fourier-domain OCT system capable of acquiring 26,000 axial-scans per second was used. It has an axial resolution of 5μm ...
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    12. Volumetric and quantitative imaging of retinal blood flow in rats with optical microangiography

      Volumetric and quantitative imaging of retinal blood flow in rats with optical microangiography
      In this paper, we present methods for 3D visualization and quantitative measurements of retinal blood flow in rats by the use of optical microangiography imaging technique (OMAG). We use ultrahigh sensitive OMAG to provide high-quality 3D RBF perfusion maps in the rat eye, from which the Doppler angle, as well as the diameters of blood vessels, are evaluated. Estimation of flow velocity (i.e. axial flow velocity) is achieved by ...
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    13. Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography

      Volumetric in-vivo imaging of intra-cochlear microstructures and microvascular perfusion in mice using high-speed spectral domain optical coherence tomography and ultra-high sensitive optical microangiography
      Studying the inner ear microstructures and microvascular dynamics is extremely important to understand the cochlear function and to further advance the diagnosis, prevention and treatment of many otologic disorders. There is considerable interest in developing new methods for in vivo imaging of the complex anatomy of the mammalian cochlea and the micro vascular perfusion within it for both clinical as well as fundamental studies. In this study, we explored the ...
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    14. Effect of blood vessel diameter on relative blood flow estimate in Doppler optical coherence tomography algorithms

      Effect of blood vessel diameter on relative blood flow estimate in Doppler optical coherence tomography algorithms
      In vivo measurement of blood flow in the retina has been made possible with the advent of Fourier domain optical coherence tomography (OCT). Doppler OCT has seen many advances in recent years in algorithms used for quantifying blood flow. We compare the relative retinal blood flow estimates as measured by the standard phase-resolved (PR) algorithm and the more recent moving-scatterer-sensitive (MSS) algorithm as a function of vessel size. We find ...
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  2. About Oregon Health & Science University

    Oregon Health & Science University

    Oregon Health & Science University (OHSU) is a public university in Oregon with a main campus, including three hospitals, in Portland and a smaller campus in Hillsboro. It was formed in 1974 as the University of Oregon Health Sciences Center, combining state dentistry, medicine, and nursing programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute of Science and Technology (OGI) in Hillsboro. In addition, the university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University.