1. Oregon Health & Science University

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    1. Mentioned In 325 Articles

    2. Reflectance-based projection-resolved optical coherence tomography angiography [Invited]

      Reflectance-based projection-resolved optical coherence tomography angiography [Invited]
      O ptical coherence tomography angiography (OCTA) is limited by projection artifacts from the superficial blood vessels onto deeper layers. We have recently described projection-resolved (PR) OCTA that solves the ambiguity between in situ flow and flow projection along each axial scan and suppresses the artifact on both en face and cross-sectional angiograms. While this method significantly improved the depth resolution of OCTA, the vascular integrity of the deeper layers was ...
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    3. Quantitative optical coherence tomography angiography of the peripapillary circulation in glaucoma

      Quantitative optical coherence tomography angiography of the peripapillary circulation in glaucoma
      The cause of glaucoma, a disease defined by degeneration of retinal ganglion cells associated with cupping of the optic nerve head (ONH) and progressive vision loss, continues to be debated despite numerous advances in ophthalmic imaging and diagnostics. Although elevated intraocular pressure is often implicated, many studies, using a variety of imaging techniques including plain fundus photography, fluorescein angiography, laser Doppler flowmetry, and color Doppler ultrasound (1-4), have suggested that ...
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    4. Detailed Vascular Anatomy of the Human Retina by Projection-Resolved Optical Coherence Tomography Angiography

      Detailed Vascular Anatomy of the Human Retina by Projection-Resolved Optical Coherence Tomography Angiography
      Optical coherence tomography angiography (OCTA) is a noninvasive method of 3D imaging of the retinal and choroidal circulations. However, vascular depth discrimination is limited by superficial vessels projecting flow signal artifact onto deeper layers. The projection-resolved (PR) OCTA algorithm improves depth resolution by removing projection artifact while retaining in-situ flow signal from real blood vessels in deeper layers. This novel technology allowed us to study the normal retinal vasculature in ...
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    5. Automated boundary detection of the optic disc and layer segmentation of the peripapillary retina in volumetric structural and angiographic optical coherence tomography

      Automated boundary detection of the optic disc and layer segmentation of the peripapillary retina in volumetric structural and angiographic optical coherence tomography
      To improve optic disc boundary detection and peripapillary retinal layer segmentation, we propose an automated approach for structural and angiographic optical coherence tomography. The algorithm was performed on radial cross-sectional B-scans. The disc boundary was detected by searching for the position of Bruchs membrane opening, and retinal layer boundaries were detected using a dynamic programming-based graph search algorithm on each B-scan without the disc region. A comparison of the disc ...
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    6. Automated three-dimensional registration and volume rebuilding for wide-field angiographic and structural optical coherence tomography

      Automated three-dimensional registration and volume rebuilding for wide-field angiographic and structural optical coherence tomography
      We propose a three-dimensional (3-D) registration method to correct motion artifacts and construct the volume structure for angiographic and structural optical coherence tomography (OCT). This algorithm is particularly suitable for the nonorthogonal wide-field OCT scan acquired by a ultrahigh-speed swept-source system ( 200 kHz 200kHz A-scan rate). First, the transverse motion artifacts are corrected by the between-frame registration based on en face OCT angiography (OCTA). After A-scan transverse translation between B-frames ...
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    7. Automated detection of dilated capillaries on optical coherence tomography angiography

      Automated detection of dilated capillaries on optical coherence tomography angiography
      Automated detection and grading of angiographic high-risk features in diabetic retinopathy can potentially enhance screening and clinical care. We have previously identified capillary dilation in angiograms of the deep plexus in optical coherence tomography angiography as a feature associated with severe diabetic retinopathy. In this study, we present an automated algorithm that uses hybrid contrast to distinguish angiograms with dilated capillaries from healthy controls and then applies saliency measurement to ...
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    8. Two from MIT share National Academy of Engineering Fritz J. and Dolores H. Russ Prize

      Two from MIT share National Academy of Engineering Fritz J. and Dolores H. Russ Prize
      The National Academy of Engineering (NAE) 2017 Fritz J. and Dolores H. Russ Prize was awarded to a team of researchers, including two MIT affiliates, for their work in optical coherence tomography. The award committee noted that the research demonstrated creative engineering to invent imaging technology essential for preventing blindness and treating vascular and other diseases. The Russ Prize, established in October of 1999, recognizes an outstanding bioengineering achievement in ...
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    9. Hematocrit dependence of flow signal in optical coherence tomography angiography

      Hematocrit dependence of flow signal in optical coherence tomography angiography
      The hematocrit dependence of flow signal (split-spectrum amplitude decorrelation angiography-SSADA decorrelation value) was investigated in this paper. Based on the normalized field temporal correlation function and concentration dependent particle scattering properties, the relationship between hematocrit and flow signal was analytically derived. Experimental verification of the relationship was performed with custom-designed microfluidic chips and human blood with 45%, 40% and 32% hematocrit. It was found that, in large flow channels and ...
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    10. "Nobel prize for engineering sciences" goes to MedUni Vienna researchers

      "Nobel prize for engineering sciences" goes to MedUni Vienna researchers
      Christoph Hitzenberger and Adolf Fercher from MedUni Vienna have been awarded this years Fritz J. and Dolores H. Russ Prize. The prize is awarded by the United States National Academy of Engineering (NAE) for technological developments that "have had a significant impact on society and have helped to improve human well-being". The two researchers from Vienna played a major role in the development of Optical Coherence Tomography (OCT), an examination ...
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    11. Optical coherence tomography angiography of non-exudative choroidal neovascularization

      Optical coherence tomography angiography of non-exudative choroidal neovascularization
      Age-related macular degeneration (AMD) has been classified in two groups, neovascular and non-neovascular, which historically has been synonymous with exudative and non-exudative, respectively. Neovascular AMD occurs when pathologic blood vessels, choroidal neovascularization (CNV), arise from the choroid and extend above Bruchs membrane toward the outer retina. Often these vessels are exudative in nature, resulting in leakage of fluid, lipid exudate, or blood causing vision loss. The exudation from CNV allows ...
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    12. Choriocapillaris evaluation in choroideremia using optical coherence tomography angiography

      Choriocapillaris evaluation in choroideremia using optical coherence tomography angiography
      The choriocapillaris plays an important role in supporting the metabolic demands of the retina. Studies of the choriocapillaris in disease states with optical coherence tomography angiography (OCTA) have proven insightful. However, image artifacts complicate the identification and quantification of the choriocapillaris in degenerative diseases such as choroideremia. Here, we demonstrate a supervised machine learning approach to detect intact choriocapillaris based on training with results from an expert grader. We trained ...
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    13. Optical coherence tomographic angiography of choroidal neovascularization ill-defined with fluorescein angiography

      Optical coherence tomographic angiography of choroidal neovascularization ill-defined with fluorescein angiography
      Purpose To evaluate the morphological structure of ill-defined choroidal neovascularisation (CNV) with traditional fluorescein angiography (FA) compared with optical coherence tomographic angiography (OCTA). Methods A retrospective case series study of 11 eyes with ill-defined CNV on FA was performed. Eyes were scanned with commercially available spectral-domain optical coherence tomography (OCT) (70 000 A-scans/s). The split-spectrum amplitude-decorrelation angiography (SSADA) algorithm was used to distinguish blood flow from static tissue. En ...
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    14. In vivo imaging of coral tissue and skeleton with optical coherence tomography

      In vivo imaging of coral tissue and skeleton with optical coherence tomography
      Optical coherence tomography (OCT) is a non-invasive three-dimensional imaging technique with micrometer resolution allowing microstructural characterization of tissues in vivo and in real time. We present the first application of OCT for in vivo imaging of tissue and skeleton structure of intact living corals spanning a variety of morphologies and tissue thickness. OCT visualized different coral tissue layers (e.g. endoderm vs ectoderm), special structures such as mesenterial filaments and ...
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    15. 1-15 of 325 1 2 3 4 ... 20 21 22 »
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  2. About Oregon Health & Science University

    Oregon Health & Science University

    Oregon Health & Science University (OHSU) is a public university in Oregon with a main campus, including three hospitals, in Portland and a smaller campus in Hillsboro. It was formed in 1974 as the University of Oregon Health Sciences Center, combining state dentistry, medicine, and nursing programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute of Science and Technology (OGI) in Hillsboro. In addition, the university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University.