1. Oregon Health & Science University

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    1. Mentioned In 286 Articles

    2. Beyond Better Clinical Care: Optical Coherence Tomography's Economic Impact

      Beyond Better Clinical Care: Optical Coherence Tomography's Economic Impact
      The optical coherence tomography (OCT) industry has grown dramatically in its first 25 years, and while the positive effects on patient clinical care are the most important measure of OCT's success, its contributions to the economy in jobs, tax receipts, and healthcare savings are also noteworthy. The field of optical coherence tomography (OCT) has grown dramatically since its discovery in the early 1990s. The commercialization and growth of OCT ...
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    3. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF CHOROIDAL NEOVASCULARIZATION IN FOUR INHERITED RETINAL DYSTROPHIES

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF CHOROIDAL NEOVASCULARIZATION IN FOUR INHERITED RETINAL DYSTROPHIES
      Purpose: To demonstrate the clinical utility of optical coherence tomography (OCT) angiography (OCT-A) in inherited retinal dystrophies complicated by choroidal neovascularization (CNV). Methods: Optical coherence tomography angiography and structural OCT were performed using a 70-kHz spectral domain OCT system using the split-spectrum amplitude-decorrelation angiography algorithm. Semiautomated image processing software was used to segment and measure the CNV. Results: Four participants were enrolled to study the following inherited retinal dystrophies complicated ...
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    4. Automated segmentation and enhancement of optical coherence tomography-acquired images of rodent brain

      Automated segmentation and enhancement of optical coherence tomography-acquired images of rodent brain
      Background Optical coherence tomography (OCT) is a non-invasive optical imaging method that has proven useful in various fields such as ophthalmology, dermatology and neuroscience. In ophthalmology, significant progress has been made in retinal layer segmentation and enhancement of OCT images. There are also segmentation algorithms to separate epidermal and dermal layers in OCT-acquired images of human skin. New Method We describe simple image processing methods that allow automatic segmentation and ...
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    5. Projection-resolved optical coherence tomographic angiography

      Projection-resolved optical coherence tomographic angiography
      Shadowgraphic projection artifacts from superficial vasculature interfere with the visualization of deeper vascular networks in optical coherence tomography angiography (OCT-A). We developed a novel algorithm to remove this artifact by resolving the ambiguity between in situ and projected flow signals. The algorithm identifies voxels with in situ flow as those where intensity-normalized decorrelation values are higher than all shallower voxels in the same axial scan line. This projection-resolved (PR) algorithm ...
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    6. OCT angiography with projection resolution algorithm quantifies retinal vessel density

      OCT angiography with projection resolution algorithm quantifies retinal vessel density
      Using OCT angiography and a novel projection resolution and reflectance compensation algorithm to remove artifact and signal effects, David Huang, MD, PhD, and colleagues found that glaucoma preferentially affects vessel density in the ganglion cell complex more than in deeper layers, according to a study presented at the American Ophthalmological Society meeting here. This year I want to talk about studying the macula in the context of glaucoma, Huang said ...
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    7. Oregon Health and Science University Receives NIH Grant for Ossicle Vibration Measurement sin Conductive Hearing Loss

      Oregon Health and Science University Receives NIH Grant for Ossicle Vibration Measurement sin Conductive Hearing Loss
      ... develop more effective treatments for patients with conductive hearing loss.

      Oregon Health and Science University Receives a 2016 NIH Grant for $418,717 for Ossicle Vibration Measurement ...

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    8. Optical Coherence Tomography Angiography in Choroideremia: Correlating Choriocapillaris Loss With Overlying Degeneration

      Optical Coherence Tomography Angiography in Choroideremia: Correlating Choriocapillaris Loss With Overlying Degeneration
      Importance Novel therapies for choroideremia, an X-linked recessive chorioretinal degeneration, demand a better understanding of the primary site(s) of cellular degeneration. Optical coherence tomography angiography allows for choriocapillaris (CC) imaging. We compared the extent of structural alterations of the CC, retinal pigment epithelium, and photoreceptors with multimodal imaging. Observations In a clinical case series conducted from September 15, 2014, through February 5, 2015, 14 eyes of 7 male patients ...
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    9. Optical coherence tomography angiography in pediatric choroidal neovascularization

      Optical coherence tomography angiography in pediatric choroidal neovascularization
      Purpose : To report two cases of pediatric choroidal neovascularization (CNV) and the associated neovascular and retinal findings identified on Optical Coherence Tomography Angiography (OCTA) imaging. Methods : A 14-year-old boy with handheld laser-induced maculopathy-related CNV and a 13-year-old boy with idiopathic CNV were evaluated with visual acuity testing, slit-lamp exam, fundus photography, fluorescein angiography, indocyanine green angiography, spectral domain optical coherence tomography, and OCTA. Results : Macular CNV were identified in both ...
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    10. Effect of Outflow Tract Banding on Embryonic Cardiac Hemodynamics

      Effect of Outflow Tract Banding on Embryonic Cardiac Hemodynamics
      We analyzed heart wall motion and blood flow dynamics in chicken embryos using in vivo optical coherence tomography (OCT) imaging and computational fluid dynamics (CFD) embryo-specific modeling. We focused on the heart outflow tract (OFT) region of day 3 embryos, and compared normal (control) conditions to conditions after performing an OFT banding intervention, which alters hemodynamics in the embryonic heart and vasculature. We found that hemodynamics and cardiac wall motion ...
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    11. Quantification of Ellipsoid Zone Changes in Retinitis Pigmentosa Using en Face Spectral Domain–Optical Coherence Tomography

      Quantification of Ellipsoid Zone Changes in Retinitis Pigmentosa Using en Face Spectral Domain–Optical Coherence Tomography
      Importance New methods are needed to quantify the change in the outer retinal structures in retinitis pigmentosa (RP). Objective To implement an alternate method for tracking ellipsoid zone (EZ) changes in RP by quantifying the EZ area on en face spectral domainoptical coherence tomographic (SD-OCT) images. Design, Setting, and Participants Data for this observational case study were collected at the Department of Ophthalmology, University of California, Los Angeles, from May ...
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    12. Automated volumetric segmentation of retinal fluid on optical coherence tomography

      Automated volumetric segmentation of retinal fluid on optical coherence tomography
      We propose a novel automated volumetric segmentation method to detect and quantify retinal fluid on optical coherence tomography (OCT). The fuzzy level set method was introduced for identifying the boundaries of fluid filled regions on B-scans (x and y-axes) and C-scans (z-axis). The boundaries identified from three types of scans were combined to generate a comprehensive volumetric segmentation of retinal fluid. Then, artefactual fluid regions were removed using morphological characteristics ...
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    13. Subclinical keratoconus detection by pattern analysis of corneal and epithelial thickness maps with optical coherence tomography

      Subclinical keratoconus detection by pattern analysis of corneal and epithelial thickness maps with optical coherence tomography
      Purpose To screen for subclinical keratoconus by analyzing corneal, epithelial, and stromal thickness map patterns with Fourier-domain optical coherence tomography (OCT). Setting Four centers in the United States. Design Cross-sectional observational study. Methods Eyes of normal subjects, subclinical keratoconus eyes, and the topographically normal eye of a unilateral keratoconus patient were studied. Corneas were scanned using a 26000 Hz Fourier-domain OCT system (RTVue). Normal subjects were divided into training and ...
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    14. Longitudinal and Cross-Sectional Analyses of Age and Intraocular Pressure Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness

      Longitudinal and Cross-Sectional Analyses of Age and Intraocular Pressure Effects on Retinal Nerve Fiber Layer and Ganglion Cell Complex Thickness
      Purpose : To study the effect of age and intraocular pressure (IOP) on retinal nerve fiber layer (NFL) and ganglion cell complex (GCC) thickness in normal eyes. Methods : We analyzed the data from subjects enrolled in the multi-center longitudinal Advanced Imaging for Glaucoma (AIG) Study (www.AIGStudy.net). The data included yearly visits from the normal subjects group in the AIGS study. Fourier-domain optical coherence tomography (OCT) was used to map ...
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    15. Post-doctoral fellowship in Optical Coherence Tomography at Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA

      Post-doctoral fellowship in Optical Coherence Tomography at Casey Eye Institute, Oregon Health & Science University, Portland, OR, USA
      ...rmation on the position, please visit www.COOLLab.net; www.octangio.net or contact Kathleen S. Torok at torok@ohsu.edu.  Applications, including a current CV, and contact details for three referees, should be submitted....
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  2. About Oregon Health & Science University

    Oregon Health & Science University

    Oregon Health & Science University (OHSU) is a public university in Oregon with a main campus, including three hospitals, in Portland and a smaller campus in Hillsboro. It was formed in 1974 as the University of Oregon Health Sciences Center, combining state dentistry, medicine, and nursing programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute of Science and Technology (OGI) in Hillsboro. In addition, the university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University.