1. Oregon Health & Science University

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    1. Mentioned In 379 Articles

    2. Systems And Methods For REFLECTANCE-BASED PROJECTION-RESOLVED Optical Coherence Tomography Angiography

      Systems And Methods For REFLECTANCE-BASED PROJECTION-RESOLVED Optical Coherence Tomography Angiography
      Embodiments provide systems and methods associated with a reflectance-based projection-resolved (rbPR) optical coherence tomography angiography (OCTA) algorithm which uses optical coherence tomography (OCT) reflectance to enhance the flow signal and suppress the projection artifacts in 3-dimensional OCTA. rbPR improves the vascular connectivity and improved the discrimination of the deeper plexus angiograms in healthy eyes, compared to prior PR-OCTA method. Additionally, rbPR removes flow projection artifacts more completely from the outer ...
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    3. Deep learning for the segmentation of preserved photoreceptors on en face optical coherence tomography in two inherited retinal diseases

      Deep learning for the segmentation of preserved photoreceptors on en face optical coherence tomography in two inherited retinal diseases
      The objective quantification of photoreceptor loss in inherited retinal degenerations (IRD) is essential for measuring disease progression, and is now especially important with the growing number of clinical trials. Optical coherence tomography (OCT) is a non-invasive imaging technology widely used to recognize and quantify such anomalies. Here, we implement a versatile method based on a convolutional neural network to segment the regions of preserved photoreceptors in two different IRDs (choroideremia ...
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    4. Automated Quantification of Nonperfusion Areas in 3 Vascular Plexuses With Optical Coherence Tomography Angiography in Eyes of Patients With Diabetes

      Automated Quantification of Nonperfusion Areas in 3 Vascular Plexuses With Optical Coherence Tomography Angiography in Eyes of Patients With Diabetes
      ... Dr Zhang is employed by Optovue Inc. These potential conflicts of interest have been reviewed and managed by Oregon Health & Science University. No other disclosures were reported. Funding/Support: This work was support...
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    5. Systems and methods of choroidal neovascularization detection using optical coherence tomography angiography

      Systems and methods of choroidal neovascularization detection using optical coherence tomography angiography
      Disclosed are systems and methods to automatically detect choroidal neovascularization (CNV) in the outer retina using OCT angiography. Further disclosed are methods of removing projection artifacts from the outer retina and for combining brightness, orientation, and position information in a context-aware saliency model to quantify CNV area in OCT angiograms.
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    6. Vitreopapillary Traction Detected by Optical Coherence Tomography

      Vitreopapillary Traction Detected by Optical Coherence Tomography
      A man in his 70s was referred for evaluation of a suspected right optic neuropathy. Visual acuity was 20/25 OU, color vision was normal, and there was a trace right relative afferent pupillary defect. Fundus examination revealed an elevated right optic disc with mildly blurred margins and vessel obscuration. Bilateral epiretinal membranes were also present. Optical coherence tomography (Cirrus OCT; Carl Zeiss Meditec, Inc) confirmed the diagnosis of vitreopapillary ...
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    7. Evaluation of Automatically Quantified Foveal Avascular Zone Metrics for Diagnosis of Diabetic Retinopathy Using Optical Coherence Tomography Angiography

      Evaluation of Automatically Quantified Foveal Avascular Zone Metrics for Diagnosis of Diabetic Retinopathy Using Optical Coherence Tomography Angiography
      Purpose : To describe an automated algorithm to quantify the foveal avascular zone (FAZ), using optical coherence tomography angiography (OCTA), and to compare its performance for diagnosis of diabetic retinopathy (DR) and association with best-corrected visual acuity (BCVA) to that of extrafoveal avascular area (EAA). Methods : We obtained 3 3-mm macular OCTA scans in diabetic patients with various levels of DR and healthy controls. An algorithm based on a generalized gradient ...
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    8. Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT

      Fast and robust standard-deviation-based method for bulk motion compensation in phase-based functional OCT
      Phase-based optical coherence tomography (OCT), such as OCT angiography (OCTA) and Doppler OCT, is sensitive to the confounding phase shift introduced by subject bulk motion. Traditional bulk motion compensation methods are limited by their accuracy and computing cost-effectiveness. In this Letter, to the best of our knowledge, we present a novel bulk motion compensation method for phase-based functional OCT. Bulk motion associated phase shift can be directly derived by solving ...
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    9. Optical Coherence Tomography Angiography and UltraWidefield Optical Coherence Tomography in a Child With Incontinentia Pigmenti

      Optical Coherence Tomography Angiography and UltraWidefield Optical Coherence Tomography in a Child With Incontinentia Pigmenti
      Incontinentia pigmenti (IP) is a rare X-linked dominant disorder that can cause retinal nonperfusion, neovascularization, and retinal detachment. Evaluation of the peripheral retinal vasculature and appropriate treatment can reduce the risk of blindness. The authors report the use of a handheld prototype optical coherence tomography angiography (OCTA) and ultra-widefield OCT (UWF-OCT) during exam under anesthesia of a 2-year-old with a history of severe early onset IP. UWF-OCT and OCTA may ...
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    10. OCT in Diagnosis of Irregular Corneas

      OCT in Diagnosis of Irregular Corneas
      This main goal of this study is to improve the detection, classification, monitoring, and treatment of irregular corneas due to keratoconus, warpage, dry eye, scar, stromal dystrophies, and other corneal conditions. The primary goal will be achieved by using optical coherence tomography (OCT) to: Develop an OCT-based system to classify and evaluate corneal-shape irregularities. Develop OCT metrics for more sensitive detection of keratoconus progression. Develop OCT-and-topography guided phototherapeutic keratectomy (PTK ...
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    11. Optical Coherence Tomography Angiography and Ultra-Widefield Optical Coherence Tomography in a Child With Incontinentia Pigmenti

      Optical Coherence Tomography Angiography and Ultra-Widefield Optical Coherence Tomography in a Child With Incontinentia Pigmenti
      Incontinentia pigmenti (IP) is a rare X-linked dominant disorder that can cause retinal nonperfusion, neovascularization, and retinal detachment. Evaluation of the peripheral retinal vasculature and appropriate treatment can reduce the risk of blindness. The authors report the use of a handheld prototype optical coherence tomography angiography (OCTA) and ultra-widefield OCT (UWF-OCT) during exam under anesthesia of a 2-year-old with a history of severe early onset IP. UWF-OCT and OCTA may ...
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    12. Automated spectroscopic retinal oximetry with visible-light optical coherence tomography

      Automated spectroscopic retinal oximetry with visible-light optical coherence tomography
      Accurate, quantitative assessment of retinal blood oxygen saturation ( sO 2 ) may provide a useful early indicator of pathophysiology in several ocular diseases. Here, with visible-light optical coherence tomography (OCT), we demonstrate an automated spectroscopic retinal oximetry algorithm to measure the sO 2 within the retinal arteries (A- sO 2 ) and veins (V- sO 2 ) in rats by automatically detecting the vascular posterior boundary on cross-sectional structural OCT. The algorithm was ...
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    13. Aqueous cell differentiation in anterior uveitis using optical coherence tomography

      Aqueous cell differentiation in anterior uveitis using optical coherence tomography
      Methods and systems for determining a percentage composition of aqueous cells in an anterior chamber of an eye of a subject based on cell reflectance distributions calculated from OCT image data are disclosed. In one example approach, determining a percentage composition of detected aqueous cells may comprise calculating a percentage of the detected aqueous cells which are polymorphonuclear and calculating a percentage of detected aqueous cells which are mononuclear.
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    14. Systems and methods of glaucoma diagnosis based on frequency analysis of inner retinal surface profile measured by optical coherence tomography

      Systems and methods of glaucoma diagnosis based on frequency analysis of inner retinal surface profile measured by optical coherence tomography
      A method for detecting glaucoma in a subject based on spatial frequency analysis of the inner limiting membrane (ILM) as obtained from optical coherence tomography (OCT) image data is disclosed. Based on the spatial frequency content of the analyzed ILM profile, a quantity called the Retinal surface contour variability (RSCV) is calculated and the presence or absence of a glaucoma condition is determined based on the RSCV magnitude.
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    15. Nerve Fiber Flux Analysis Using Wide-Field Swept-Source Optical Coherence Tomography

      Nerve Fiber Flux Analysis Using Wide-Field Swept-Source Optical Coherence Tomography
      Purpose : To devise a method to quantify nerve fibers over their arcuate courses over an extended peripapillary area using optical coherence tomography (OCT). Methods : Participants were imaged with 8 8-mm volumetric OCT scans centered at the optic disc. A new quantity, nerve fiber flux (NFF), represents the cross-sectional area transected perpendicular to the nerve fibers. The peripapillary area was divided into 64 tracks with equal flux. An iterative algorithm traced ...
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    16. Reduced Retinal Vessel Density in Primary Angle Closure Glaucoma: A Quantitative Study Using Optical Coherence Tomography Angiography

      Reduced Retinal Vessel Density in Primary Angle Closure Glaucoma: A Quantitative Study Using Optical Coherence Tomography Angiography
      Purpose: To investigate the changes in the retinal vasculature in different parts of the fundus in eyes with primary angle closure glaucoma (PACG). Methods: Healthy subjects and those with PACG were enrolled. Optical coherence tomography and a split-spectrum amplitude decorrelation angiography algorithm were used to quantify the retinal vessel densities in the parafoveal and peripapillary areas. Results: Thirty-nine eyes from 24 PACG patients and 39 eyes from 20 age- and ...
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    17. 1-15 of 379 1 2 3 4 ... 24 25 26 »
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  2. About Oregon Health & Science University

    Oregon Health & Science University

    Oregon Health & Science University (OHSU) is a public university in Oregon with a main campus, including three hospitals, in Portland and a smaller campus in Hillsboro. It was formed in 1974 as the University of Oregon Health Sciences Center, combining state dentistry, medicine, and nursing programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute of Science and Technology (OGI) in Hillsboro. In addition, the university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University.