1. Oregon Health & Science University

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    1. Mentioned In 501 Articles

    2. High speed, long range, deep penetration swept source OCT for structural and angiographic imaging of the anterior eye

      High speed, long range, deep penetration swept source OCT for structural and angiographic imaging of the anterior eye
      This study reports the development of prototype swept-source optical coherence tomography (SS-OCT) technology for imaging the anterior eye. Advances in vertical-cavity surface-emitting laser (VCSEL) light sources, signal processing, optics and mechanical designs, enable a unique combination of high speed, long range, and deep penetration that addresses the challenges of anterior eye imaging. We demonstrate SS-OCT with a 325 kHz A-scan rate, 12.2 m axial resolution (in air), and 15 ...
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    3. In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography

      In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography
      Purpose : Growing evidence suggests that dendrite retraction or degeneration in a subpopulation of the retinal ganglion cells (RGCs) may precede detectable soma abnormalities and RGC death in glaucoma. Visualization of the lamellar structure of the inner plexiform layer (IPL) could advance clinical management and fundamental understanding of glaucoma. We investigated whether visible-light optical coherence tomography (vis-OCT) could detect the difference in the IPL sublayer thicknesses between small cohorts of healthy ...
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    4. An outer hair cell-powered global hydromechanical mechanism for cochlear amplification

      An outer hair cell-powered global hydromechanical mechanism for cochlear amplification
      It is a common belief that the mammalian cochlea achieves its exquisite sensitivity, frequency selectivity, and dynamic range through an outer hair cell-based active process, or cochlear amplification. As a sound-induced traveling wave propagates from the cochlear base toward the apex, outer hair cells at a narrow region amplify the low level sound-induced vibration through a local feedback mechanism. This widely accepted theory has been tested by measuring sound-induced sub-nanometer ...
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    5. 105° field of view non-contact handheld swept-source optical coherence tomography

      105° field of view non-contact handheld swept-source optical coherence tomography
      We demonstrate a handheld swept-source optical coherence tomography (OCT) system with a 400 kHz vertical-cavity surface-emitting laser (VCSEL) light source, a non-contact approach, and an unprecedented single shot 105 field of view (FOV). We also implemented a spiral scanning pattern allowing real-time visualization with improved scanning efficiency. To the best of our knowledge, this is the widest FOV achieved in a portable non-contact OCT retinal imaging system to date. Improvements ...
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    6. Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic

      Prospective evaluation of optical coherence tomography for disease detection in the Casey mobile eye clinic
      This study was designed to evaluate iVue Spectral-domain optical coherence tomography (SD-OCT) effectiveness in screening for eye disease compared to clinical examination. Subjects were recruited from the Casey Eye Community Outreach Program Mobile Clinic during its routinely scheduled outreach clinics to indigent, underserved populations throughout Oregon. Macular optical coherence tomography interpretation and automated optical coherence tomography analysis were compared to the clinical examination, with specific attention to findings indicative of ...
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    7. Deep learning-based signal-independent assessment of macular avascular area on 6×6 mm optical coherence tomography angiogram in diabetic retinopathy: a comparison to instrument-embedded software

      Deep learning-based signal-independent assessment of macular avascular area on 6×6 mm optical coherence tomography angiogram in diabetic retinopathy: a comparison to instrument-embedded software
      Synopsis: A deep-learning-based macular extrafoveal avascular area (EAA) on a 66 mm optical coherence tomography (OCT) angiogram is less dependent on the signal strength and shadow artefacts, providing better diagnostic accuracy for diabetic retinopathy (DR) severity than the commercial software measured extrafoveal vessel density (EVD). Aims: To compare a deep-learning-based EAA to commercial output EVD in the diagnostic accuracy of determining DR severity levels from 66 mm OCT angiography (OCTA ...
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    8. Oregon Health and Science University Receives NIH Grant for OCT Angiography for Neovascular Age-related Macular Degeneration

      Oregon Health and Science University Receives NIH Grant for OCT Angiography for Neovascular Age-related Macular Degeneration
      ...cular AMD. OCTA is nearing its potential to replace the need for invasive FA.

      Oregon Health and Science University Receives a 2021 NIH Grant for $471,602 for OCT Angiography for Neovascula...

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    9. High-Speed, Long-Range Swept-Source Optical Coherence Tomography for the Anterior Segment of the Eye

      High-Speed, Long-Range Swept-Source Optical Coherence Tomography for the Anterior Segment of the Eye
      Purpose : The anterior segment (AS) of the eye is of interest in multiple diseases and procedures, including glaucoma, ocular surface inflammation, and refractive / cataract surgeries. Visualizing the anterior eye using optical coherence tomography (OCT) has unique challenges, and AS OCT technology is less developed than retinal imaging. We developed next generation swept-source OCT (SS-OCT) technology to enable high-speed and long-range AS structural and angiographic imaging in clinical settings. Methods : We ...
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    10. Optical coherence tomographic angiography study of perfusion recovery after surgical lowering of intraocular pressure

      Optical coherence tomographic angiography study of perfusion recovery after surgical lowering of intraocular pressure
      We investigated the time and location of retinal perfusion recovery after surgical intraocular pressure (IOP) lowering in glaucoma by using optical coherent tomography angiography (OCTA). Seventeen patients were analyzed. The 4.54.5-mm OCTA scans centered on the disc were performed preoperatively and postoperatively at 6 weeks, 3 months, and 6 months. The peripapillary retinal nerve fiber layer (NFL) thickness, NFL plexus capillary density (NFLP-CD) and visual field (VF) were ...
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    11. Oregon Health & Science University Receives NIH Grant for Visible-light OCT angiography, velocimetry, and oximetry for characterizing retinal vascular alterations in glaucoma

      Oregon Health & Science University Receives NIH Grant for Visible-light OCT angiography, velocimetry, and oximetry for characterizing retinal vascular alterations in glaucoma
      ...ed susceptibility in advanced glaucoma will lead to improved treatments for these highly vulnerable patients. Oregon Health & Science University Receives a 2021 NIH Grant for $500,718 for Visible-light OCT angiography, v...
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    12. Normative intercapillary distance and vessel density data in the temporal retina assessed by wide-field spectral-domain optical coherence tomography angiography

      Normative intercapillary distance and vessel density data in the temporal retina assessed by wide-field spectral-domain optical coherence tomography angiography
      A limitation of conventional optical coherence tomography angiography (OCTA) is the limited field of view normally used in data acquisition. As the technology improves, larger fields of view that capture information away from the macular are being explored in order to provide an enhanced ability to detect pathology. However, normative measurements for important OCTA metrics like vessel density and intercapillary distance are not currently well-characterized in the peripheral retina. In ...
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    13. Phase-corrected buffer averaging for enhanced OCT angiography using FDML laser

      Phase-corrected buffer averaging for enhanced OCT angiography using FDML laser
      Megahertz-rate optical coherence tomography angiography (OCTA) is highly anticipated as an ultrafast imaging tool in clinical settings. However, shot-noise-limited sensitivity is inevitably reduced in high-speed imaging systems. In this Letter, we present a coherent buffer averaging technique for use with a Fourier-domain mode-locked (FDML) laser to improve OCTA contrast at 1060 nm MHz-rate retinal imaging. Full characterization of spectral variations among the FDML buffers and a numerical correction method are ...
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    14. Accuracy of OCT-derived net corneal astigmatism measurement

      Accuracy of OCT-derived net corneal astigmatism measurement
      Purpose: To assess the repeatability and accuracy of corneal astigmatism measurement with a spectral-domain optical coherence tomography (OCT) system (Avanti, Optovue) and compare them with Scheimpflug imaging (Pentacam HR, Oculus) and swept-source optical biometry (IOLMaster 700, Carl Zeiss Mediatec AG). Setting: Casey Eye Institute, Oregon Health Science University, Portland, Oregon, USA. Design: Prospective cross-sectional observational study. Methods: Sixty pseudophakic eyes with monofocal non-toric intraocular lens that previously had refractive surgery ...
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    15. Oregon Health & Science University Receives NIH Grant for The Mechanical and Ionic Roles of Cochlear fluids in Hearing and Hearing Loss

      Oregon Health & Science University Receives NIH Grant for The Mechanical and Ionic Roles of Cochlear fluids in Hearing and Hearing Loss
      ...orti function but open a path to pharmacological interventions to treat tectorial membrane calcium pathology. Oregon Health & Science University Receives a 2021 NIH Grant for $593,243 for The Mechanical and Ionic Roles o...
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    16. 1-15 of 501 1 2 3 4 ... 32 33 34 »
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  2. About Oregon Health & Science University

    Oregon Health & Science University

    Oregon Health & Science University (OHSU) is a public university in Oregon with a main campus, including three hospitals, in Portland and a smaller campus in Hillsboro. It was formed in 1974 as the University of Oregon Health Sciences Center, combining state dentistry, medicine, and nursing programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute of Science and Technology (OGI) in Hillsboro. In addition, the university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University.