1. Oregon Health & Science University

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    1. Mentioned In 336 Articles

    2. Extended axial imaging range, widefield swept source optical coherence tomography angiography

      Extended axial imaging range, widefield swept source optical coherence tomography angiography
      We developed a high-speed, swept source OCT system for widefield OCT angiography (OCTA) imaging. The system has an extended axial imaging range of 6.6 mm. An electrical lens is used for fast, automatic focusing. The recently developed split-spectrum amplitude and phase-gradient angiography allow high-resolution OCTA imaging with only two B-scan repetitions. An improved post-processing algorithm effectively removed trigger jitter artifacts and reduced noise in the flow signal. We demonstrated ...
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    3. Optical Coherence Tomography Angiography of the Eye

      Optical Coherence Tomography Angiography of the Eye
      Optical coherence tomography (OCT) angiography is an important new imaging modality that is already being used by ophthalmologists in retina centers worldwide. It uses motion as intrinsic contrast, thus obviating the need to inject any intravenous dye. It uses infrared light that is invisible to the patient, and only requires few seconds per scan. This makes it both easier to use and much better tolerated by patients than traditional dye-based ...
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    4. OHSU Receives NIH Grant f for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy

      OHSU Receives NIH Grant f for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy
      Oregon Health Science University Receives a 2017 NIH Grant for $487,587 for Wide-Field and Projection-Resolved Optical Coherence Tomography Angiography in Diabetic Retinopathy. The principal investigator is Yali Jia. The program began in 2017 and ends in 2021. Below is a summary of the proposed work. Our group has demonstrated that optical coherence tomography angiography (OCTA) can address many of the disadvantages of fluorescein angiography (FA) in diabetic retinopathy (DR ...
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    5. OHSU Receives NIH Grant for Dynamic Changes in the Chick Developing Heart in Response to Altered Hemodynamics

      OHSU Receives NIH Grant for Dynamic Changes in the Chick Developing Heart in Response to Altered Hemodynamics
      Oregon Health Science University Receives a 2017 NIH Grant for $414,360 for Dynamic Changes in the Chick Developing Heart in Response to Altered Hemodynamics. The principal investigator is Sandra Rugonyi. The program began in 2008 and ends in 2018. Below is a summary of the proposed work. Project Summary About 1% newborn babies have congenital heart disease (CHD), the leading cause of death among children. The majority of CHD ...
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    6. OHSU Receives NIH Grant for Studies in Glaucomatous Optic Nerve Damage

      OHSU Receives NIH Grant  for Studies in Glaucomatous Optic Nerve Damage
      Oregon Health Science University Receives a 2017 NIH Grant for $562,073 for Studies in Glaucomatous Optic Nerve Damage. The principal investigator is John Morrison. The program began in 1993 and ends in 2018. Below is a summary of the proposed work. Understanding cellular mechanisms of axonal injury from elevated intraocular pressure (IOP) is essential for developing glaucoma treatments that will protect the optic nerve. We have determined that an ...
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    7. Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography

      Interchangeability and reliability of macular perfusion parameter measurements using optical coherence tomography angiography
      Aim The aim of the study was to investigate the interchangeability and reliability of macular perfusion measurements using optical coherence tomography angiography. Methods A prospective cross-sectional observational study. Healthy adult Chinese subjects were recruited. Macular perfusion parameters were automatically analysed by software included in a spectral-domain optical coherence tomography system. The vessel density (VD) of the whole, parafovea, superior-hemi, inferior-hemi, fovea, temporal, superior, nasal and inferior quadrants as well as ...
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    8. Distinguishing between contact lens warpage and ectasia: Usefulness of optical coherence tomography epithelial thickness mapping

      Distinguishing between contact lens warpage and ectasia: Usefulness of optical coherence tomography epithelial thickness mapping
      Purpose To distinguish between corneal ectasia and contact lensrelated warpage by characteristic patterns on corneal topography and optical coherence tomography (OCT) epithelial thickness maps. Setting Casey Eye Institute, Portland, Oregon, USA. Design Prospective and retrospective case series. Methods Axial and mean power maps were obtained on corneal topography systems. Epithelial thickness maps were generated using RTVue OCT. A sector divider was applied to all maps. The locations of the minimum ...
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    9. Handheld optical coherence tomography angiography

      Handheld optical coherence tomography angiography
      We developed a handheld optical coherence tomography angiography (OCTA) system using a 100-kHz swept-source laser. The handheld probe weighs 0.4 kg and measures 20.6 12.8 4.6 cm 3 . The system has dedicated features for handheld operation. The probe is equipped with a mini iris camera for easy alignment. Real-time display of the en face OCT and cross-sectional OCT images in the system allows accurately locating the ...
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    10. Feature Of The Week 03/05/2017: In Vivo Imaging of Coral Tissue and Skeleton with Optical Coherence Tomography

      Feature Of The Week 03/05/2017: In Vivo Imaging of Coral Tissue and Skeleton with Optical Coherence Tomography
      Optical coherence tomography (OCT) is a non-invasive three-dimensional imaging technique with micrometer resolution allowing microstructural characterization of tissues in vivo and in real time. We present the first application of OCT for in vivo imaging of tissue and skeleton structure of intact living corals spanning a variety of morphologies and tissue thickness. OCT visualized different coral tissue layers (e.g. endoderm vs ectoderm), special structures such as mesenterial filaments and ...
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    11. In vivo imaging of coral tissue and skeleton with optical coherence tomography

      In vivo imaging of coral tissue and skeleton with optical coherence tomography
      Application of optical coherence tomography (OCT) for in vivo imaging of tissue and skeleton structure of intact living corals enabled the non-invasive visualization of coral tissue layers (endoderm versus ectoderm), skeletal cavities and special structures such as mesenterial filaments and mucus release from intact living corals. Coral host chromatophores containing green fluorescent protein-like pigment granules appeared hyper-reflective to near-infrared radiation allowing for excellent optical contrast in OCT and a rapid ...
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    12. Non-invasive 3D imaging and measuring of anterior chamber angle of the eye

      Non-invasive 3D imaging and measuring of anterior chamber angle of the eye
      Embodiments of OCT measurement and analysis techniques described herein enable precise 3D anterior chamber angle measurement from major, pertinent landmarks in the eye. Such techniques result in a more reliable, quantifiable angle measurement technique that is both non-invasive and non-contact in nature, thereby improving clinical practicality, while improving patient comfort and care. For example, a method is provided for in vivo imaging of an eye, including taking a plurality of ...
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    13. Reflectance-based projection-resolved optical coherence tomography angiography [Invited]

      Reflectance-based projection-resolved optical coherence tomography angiography [Invited]
      O ptical coherence tomography angiography (OCTA) is limited by projection artifacts from the superficial blood vessels onto deeper layers. We have recently described projection-resolved (PR) OCTA that solves the ambiguity between in situ flow and flow projection along each axial scan and suppresses the artifact on both en face and cross-sectional angiograms. While this method significantly improved the depth resolution of OCTA, the vascular integrity of the deeper layers was ...
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    14. Quantitative optical coherence tomography angiography of the peripapillary circulation in glaucoma

      Quantitative optical coherence tomography angiography of the peripapillary circulation in glaucoma
      The cause of glaucoma, a disease defined by degeneration of retinal ganglion cells associated with cupping of the optic nerve head (ONH) and progressive vision loss, continues to be debated despite numerous advances in ophthalmic imaging and diagnostics. Although elevated intraocular pressure is often implicated, many studies, using a variety of imaging techniques including plain fundus photography, fluorescein angiography, laser Doppler flowmetry, and color Doppler ultrasound (1-4), have suggested that ...
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    15. Detailed Vascular Anatomy of the Human Retina by Projection-Resolved Optical Coherence Tomography Angiography

      Detailed Vascular Anatomy of the Human Retina by Projection-Resolved Optical Coherence Tomography Angiography
      Optical coherence tomography angiography (OCTA) is a noninvasive method of 3D imaging of the retinal and choroidal circulations. However, vascular depth discrimination is limited by superficial vessels projecting flow signal artifact onto deeper layers. The projection-resolved (PR) OCTA algorithm improves depth resolution by removing projection artifact while retaining in-situ flow signal from real blood vessels in deeper layers. This novel technology allowed us to study the normal retinal vasculature in ...
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  2. About Oregon Health & Science University

    Oregon Health & Science University

    Oregon Health & Science University (OHSU) is a public university in Oregon with a main campus, including three hospitals, in Portland and a smaller campus in Hillsboro. It was formed in 1974 as the University of Oregon Health Sciences Center, combining state dentistry, medicine, and nursing programs into a single center. It was renamed Oregon Health Sciences University in 1981 and took its current name in 2001, as part of a merger with the Oregon Graduate Institute of Science and Technology (OGI) in Hillsboro. In addition, the university has several partnership programs including a joint PharmD Pharmacy program with Oregon State University.