1. OptoVibronex

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    2. Comparative “virtual biopsies” of normal skin and skin lesions using vibrational optical coherence tomography

      Comparative “virtual biopsies” of normal skin and skin lesions using vibrational optical coherence tomography
      Background Increased tissue stiffness (also termed modulus) has been shown to be a characteristic of potential tumor metastasis. Measured values of the stiffness of tumors and cancer cells are reported in the literature to increase compared to neighboring normal tissues. Yet the relationship between the mechanical properties of cells and the extracellular matrix has yet to be correlated with the histopathology of cancerous lesions. Materials and Methods We have developed ...
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  2. About OptoVibronex

    OptoVibronex

    OptoVibronex has developed an instrument to combine optical coherence tomography (OCT) imaging with vibrational analysis (VOCT) to image and to analyze the physical properties of tissues non-invasively and non-destructively. Using images generated by OCT and maps of the modulus as a function of position, we show that it is possible to determine the margins of lesions. Using the OptoScope it is possible to define characteristic lesion “finger prints” to discern benign from malignant skin lesions and be able to detect cancerous lesions early in the growth process.