1. NYU Grossman School of Medicine

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    1. Mentioned In 57 Articles

    2. New York University School of Medicine Receives NIH Grant for Full Field OCT for Novel Glaucoma Diagnostics for Structure and Function

      New York University School of Medicine Receives NIH Grant for Full Field OCT for Novel Glaucoma Diagnostics for Structure and Function
      New York University School of Medicine Received a 2022 NIH Grant for $666,893 for Full Field OCT for Novel Glaucoma Diagnostics for Structure and Function. The principal investigator is Joel Schuman. Below is a summary of the proposed study. Glaucoma is a leading cause of vision morbidity and blindness worldwide. Early disease detection and sensitive monitoring of progression are crucial to allow timely treatment for preservation of vision. The ...
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    3. Visible Light Optical Coherence Tomography Reveals the Relationship of the Myoid and Ellipsoid to Band 2 in Humans

      Visible Light Optical Coherence Tomography Reveals the Relationship of the Myoid and Ellipsoid to Band 2 in Humans
      Purpose: We employ visible light optical coherence tomography (OCT) to investigate the relationship between the myoid, ellipsoid, and band 2 in the living human retina. Rather than refute existing theories, we aim to reveal new bands and better delineate the structures at hand. Methods: An upgraded spectral/Fourier domain visible light OCT prototype, with 1.0-m axial resolution, imaged 13 eyes of 13 young adult human subjects (23-40 years old ...
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    4. Normative Data and Conversion Equation for Spectral-Domain Optical Coherence Tomography in an International Healthy Control Cohort

      Normative Data and Conversion Equation for Spectral-Domain Optical Coherence Tomography in an International Healthy Control Cohort
      Background: Spectral-domain (SD-) optical coherence tomography (OCT) can reliably measure axonal (peripapillary retinal nerve fiber layer [pRNFL]) and neuronal (macular ganglion cell + inner plexiform layer [GCIPL]) thinning in the retina. Measurements from 2 commonly used SD-OCT devices are often pooled together in multiple sclerosis (MS) studies and clinical trials despite software and segmentation algorithm differences; however, individual pRNFL and GCIPL thickness measurements are not interchangeable between devices. In some circumstances ...
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    5. Evolution of the 'omega sign' on optical coherence tomography

      Evolution of the 'omega sign' on optical coherence tomography
      Purpose: To present the early post-operative evolution of retained subretinal perfluoro-n-octane (PFO) as captured on OCT. Methods: Case report of a patient. Results: A 58-year-old woman was noted to have subretinal PFO after undergoing autologous retinal graft for macular hole closure under PFO tamponade. Serial OCT identified the subretinal PFO as early as the first postoperative day and demonstrates progressive consolidation and encapsulation of the PFO bubble by the surrounding ...
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    6. Subcellular Comparison of Visible-Light Optical Coherence Tomography and Electron Microscopy in the Mouse Outer Retina

      Subcellular Comparison of Visible-Light Optical Coherence Tomography and Electron Microscopy in the Mouse Outer Retina
      Purpose: We employed in vivo, 1.0-m axial resolution visible-light optical coherence tomography (OCT) and ex vivo electron microscopy (EM) to investigate three subcellular features in the mouse outer retina: reflectivity oscillations inner to band 1 (study 1); hyperreflective band 2, attributed to the ellipsoid zone or inner segment/outer segment (IS/OS) junction (study 2); and the hyperreflective retinal pigment epithelium (RPE) within band 4 (study 3). Methods: Pigmented ...
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    7. The Development and Clinical Application of Innovative Optical Ophthalmic Imaging Techniques

      The Development and Clinical Application of Innovative Optical Ophthalmic Imaging Techniques
      The field of ophthalmic imaging has grown substantially over the last years. Massive improvements in image processing and computer hardware have allowed the emergence of multiple imaging techniques of the eye that can transform patient care. The purpose of this review is to describe the most recent advances in eye imaging and explain how new technologies and imaging methods can be utilized in a clinical setting. The introduction of optical ...
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    8. Vitamin A deficiency and the retinal “double carrot” sign with optical coherence tomography

      Vitamin A deficiency and the retinal “double carrot” sign with optical coherence tomography
      Background Spectral-domain optical coherence tomography (SD-OCT) and full-field electroretinography (ERG) allow retinal assessment with vitamin A deficiency (VAD). Using SD-OCT, this study aimed to characterize and follow a novel retinal abnormality in patients with VAD and intramuscular supplementation. Methods Patients with VAD were retrospectively reviewed, including SD-OCT and electroretinography. Results Three patients had VAD following bariatric or colon surgery and varying supplementation. All had nyctalopia, extinguished scotopic rod-specific function with ...
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    9. The Role of Optical Coherence Tomography Criteria and Machine Learning in Multiple Sclerosis and Optic Neuritis Diagnosis

      The Role of Optical Coherence Tomography Criteria and Machine Learning in Multiple Sclerosis and Optic Neuritis Diagnosis
      Background and objectives: Recent studies have suggested that inter-eye differences (IEDs) in peripapillary retinal nerve fiber layer (pRNFL) or ganglion cell+inner plexiform (GCIPL) thickness by spectral-domain optical coherence tomography (SD-OCT) may identify people with a history of unilateral optic neuritis (ON). However, this requires further validation. Machine learning classification may be useful for validating thresholds for OCT IEDs and for examining added utility for visual function tests, such as ...
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    10. 3D Microstructure of the Healthy Non-Human Primate Lamina Cribrosa by Optical Coherence Tomography Imaging

      3D Microstructure of the Healthy Non-Human Primate Lamina Cribrosa by Optical Coherence Tomography Imaging
      Purpose: The lamina cribrosa (LC) has an important role in the pathophysiology of ocular diseases. The purpose of this study is to characterize in vivo, noninvasively, and in 3D the structure of the LC in healthy non-human primates (NHPs). Methods: Spectral-domain optical coherence tomography (OCT; Leica, Chicago, IL) scans of the optic nerve head (ONH) were obtained from healthy adult rhesus macaques monkeys. Using a previously reported semi-automated segmentation algorithm ...
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    11. Virtual Reality Oculokinetic Perimetry Test Reproducibility and Relationship to Conventional Perimetry and OCT

      Virtual Reality Oculokinetic Perimetry Test Reproducibility and Relationship to Conventional Perimetry and OCT
      Purpose Vivid Vision Perimetry (VVP; Vivid Vision, Inc) is a novel method for performing in-office and home-based visual field assessment using a virtual reality platform and oculokinetic perimetry. Here we examine the reproducibility of VVP Swift and compare results with conventional standard automated perimetry (SAP) and spectral-domain (SD) OCT. Design Cross-sectional study. Participants Fourteen eyes of 7 patients with open-angle glaucoma (OAG) (average age, 64.6 years; 29% women) and ...
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    12. In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography

      In Vivo Sublayer Analysis of Human Retinal Inner Plexiform Layer Obtained by Visible-Light Optical Coherence Tomography
      Purpose : Growing evidence suggests that dendrite retraction or degeneration in a subpopulation of the retinal ganglion cells (RGCs) may precede detectable soma abnormalities and RGC death in glaucoma. Visualization of the lamellar structure of the inner plexiform layer (IPL) could advance clinical management and fundamental understanding of glaucoma. We investigated whether visible-light optical coherence tomography (vis-OCT) could detect the difference in the IPL sublayer thicknesses between small cohorts of healthy ...
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    13. Proactive spectrometer matching for excess noise suppression in balanced visible light optical coherence tomography (OCT)

      Proactive spectrometer matching for excess noise suppression in balanced visible light optical coherence tomography (OCT)
      Supercontinuum sources for visible light spectral domain OCT (SDOCT) are noisy and often expensive. Balanced detection can reduce excess noise, but is rarely used in SDOCT. Here, we show that balanced detection can achieve effective excess noise cancellation across all depths if two linear array spectrometers are spectrally well-matched. We propose excess noise correlation matrices as tools to achieve such precise spectral matching. Using optomechanical adjustments, while monitoring noise correlations ...
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    14. Open Conjunctival Approach for Sub-Tenon's Xen Gel Stent Placement and Bleb Morphology by Anterior Segment Optical Coherence Tomography

      Open Conjunctival Approach for Sub-Tenon's Xen Gel Stent Placement and Bleb Morphology by Anterior Segment Optical Coherence Tomography
      Precis: Sub-Tenons implantation of the Xen Gel stent resulted in significant intraocular pressure lowering along with a low rate of postoperative bleb needling, and a favorable bleb morphology on anterior segment optical coherence tomography. Purpose: To assess clinical outcomes and bleb morphology following sub-Tenons implantation of the Xen Gel Stent (Allergan Inc., Dublin, Ireland). Methods: The medical records of patients who underwent sub-Tenons Xen Gel Stent implantation with intraoperative mitomycin-C ...
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    15. Optical Coherence Tomography and Glaucoma

      Optical Coherence Tomography and Glaucoma
      Early detection and monitoring are critical to the diagnosis and management of glaucoma, a progressive optic neuropathy that causes irreversible blindness. Optical coherence tomography (OCT) has become a commonly utilized imaging modality that aids in the detection and monitoring of structural glaucomatous damage. Since its inception in 1991, OCT has progressed through multiple iterations, from time-domain OCT, to spectral-domain OCT, to swept-source OCT, all of which have progressively improved the ...
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  2. About NYU Grossman School of Medicine

    NYU Grossman School of Medicine

    NYU Langone Medical Center is an academic medical center located in New York City , New York , United States , affiliated with New York University . The Medical Center comprises the NYU School of Medicine and three hospitals: Tisch Hospital , the Rusk Institute of Rehabilitation Medicine , and the Hospital for Joint Diseases , and recently NYU Lutheran Medical Center . [1] NYU Langone Medical Center also operates over thirty ambulatory facilities in Manhattan, Brooklyn, Queens and Long Island. [2] In 2016, NYU Langone Medical Center acquired Winthrop University Hospital . [3] NYU Langone Medical Center overlooks the East River .