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    1. Mentioned In 105 Articles

    3. Human Parafoveal Capillary Vascular Anatomy and Connectivity Revealed by Optical Coherence Tomography Angiography

      Explore IOVS Journal Ophthalmology
      Human Parafoveal Capillary Vascular Anatomy and Connectivity Revealed by Optical Coherence Tomography Angiography
      Purpose : To assess the connection among arterioles, venules, and capillaries in three retinal capillary plexuses using optical coherence tomography angiography (OCTA). Methods : This was a prospective, cross-sectional, observational study including 20 eyes of 10 healthy subjects. En face and cross-sectional OCTA images were segmented to study the superficial (SCP), middle (MCP), and deep capillary plexuses (DCP). Using thin slabs and manual segmentation within the three plexuses, we examined the connections ...
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      Mentions: Northwestern University

    4. Visible-light optical coherence tomography oximetry based on circumpapillary scan and graph-search segmentation

      Explore OSA | OSA Publishing Ophthalmology
      Visible-light optical coherence tomography oximetry based on circumpapillary scan and graph-search segmentation
      Visible-light optical coherence tomography (vis-OCT) enables retinal oximetry by measuring the oxygen saturation of hemoglobin (sO 2 ) from within individual retinal blood vessels. The sO 2 calculation requires reliable estimation of the true spectrum of backscattered light from the posterior vessel wall. Unfortunately, subject motion and image noise make averaging from multiple A-lines at the same depth position challenging, and lead to inaccurate sO 2 estimation. In this study, we ...
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      Mentions: Northwestern University Hao F. Zhang

    5. RESIDUAL CHOROIDAL VESSELS IN ATROPHY CAN MASQUERADE AS CHOROIDAL NEOVASCULARIZATION ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Introducing a Clinical and Software Approach

      Explore LWW Online Ophthalmology
      RESIDUAL CHOROIDAL VESSELS IN ATROPHY CAN MASQUERADE AS CHOROIDAL NEOVASCULARIZATION ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Introducing a Clinical and Software Approach
      Purpose: To present a postprocessing approach in optical coherence tomography angiography (OCTA) to facilitate the visualization and interpretation of lesions in age-related macular degeneration with coexisting atrophy and choroidal neovascularization (CNV). Methods: This retrospective study included 32 eyes of 26 patients with atrophy and treated CNV and 8 eyes with treatment-naive geographic atrophy . En face optical coherence tomography slabs highlighting atrophy were pseudocolored and merged with the corresponding OCTA. Cross-sectional ...
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      Mentions: Northwestern University

    6. Importance of Considering the Middle Capillary Plexus on OCT Angiography in Diabetic Retinopathy

      Explore IOVS Journal Ophthalmology
      Importance of Considering the Middle Capillary Plexus on OCT Angiography in Diabetic Retinopathy
      Purpose : To quantify microvasculature changes in the superficial (SCP), middle (MCP), and deep capillary plexuses (DCP) in diabetic retinopathy (DR). Methods : Retrospective cross-sectional study at a tertiary academic referral center, in which 26 controls (44 eyes), 27 diabetic subjects without retinopathy (44 eyes), 32 subjects with nonproliferative retinopathy (52 eyes), and 27 subjects with proliferative retinopathy (40 eyes) were imaged with optical coherence tomography angiography (OCTA). Outcome measures included parafoveal ...
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      Mentions: Northwestern University

    7. MULTILEVEL ISCHEMIA IN DISORGANIZATION OF THE RETINAL INNER LAYERS ON PROJECTION-RESOLVED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Explore LWW Online Ophthalmology
      MULTILEVEL ISCHEMIA IN DISORGANIZATION OF THE RETINAL INNER LAYERS ON PROJECTION-RESOLVED OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To examine the relationship between ischemia and disorganization of the retinal inner layers ( DRIL ). Methods: Cross-sectional retrospective study of 20 patients (22 eyes) with diabetic retinopathy presenting to a tertiary academic referral center, who had DRIL on structural optical coherence tomography ( OCT ) using Spectralis HRA + OCT (Heidelberg Engineering, Heidelberg, Germany) and OCT angiography with XR Avanti (Optovue Inc, Fremont, CA) on the same day. Optical coherence tomography angiography images ...
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      Mentions: Optovue Heidelberg Engineering Northwestern University

    8. Optical Coherence Tomography Angiography In ADULT-ONSET Foveomacular Vitelliform Dystrophy

      Explore LWW Online Ophthalmology
      Optical Coherence Tomography Angiography In ADULT-ONSET Foveomacular Vitelliform Dystrophy
      Purpose: To determine the ability of optical coherence tomography angiography (OCTA) to detect choroidal neovascularization (CNV) in the pseudohypopyon stage of adult-onset foveomacular vitelliform dystrophy. Methods: Prospective case series of eight consecutive patients with adult-onset foveomacular vitelliform dystrophy with at least one eye in the pseudohypopyon stage (a total of 14 eyes). Patients were assessed with spectral domain OCT, flourescein angiography, and OCTA. Main outcome measures were the presence or ...
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      Mentions: Northwestern University

    10. In vivo broadband visible light optical coherence tomography probe enables inverse spectroscopic analysis

      Explore OSA | OSA Publishing Probes
      In vivo broadband visible light optical coherence tomography probe enables inverse spectroscopic analysis
      We report the design and characterization of a 6 mm outer diameter pull-back circumferential scanning visible optical coherence tomography probe. The probes large visible bandwidth (500695 nm) allowed for inverse spectroscopic analysis and an axial resolution of 1.1 m 1.1m in tissue. We verify spectral imaging capabilities by measuring microsphere backscattering spectra and demonstrate in vivo spatial nanoscale characterization of tissue.
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      Mentions: Northwestern University Vadim Backman Boston University

    11. Visible-light optical coherence tomography: a review

      Explore SPIE Digital Library
      Visible-light optical coherence tomography: a review
      Visible-light optical coherence tomography (vis-OCT) is an emerging imaging modality, providing new capabilities in both anatomical and functional imaging of biological tissue. It relies on visible light illumination, whereas most commercial and investigational OCTs use near-infrared light. As a result, vis-OCT requires different considerations in engineering design and implementation but brings unique potential benefits to both fundamental research and clinical care of several diseases. Here, we intend to provide a ...
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      Mentions: Northwestern University Hao F. Zhang

    12. Small Hyperreflective Intraretinal Material Observable on Spectral-Domain Optical Coherence Tomography in High Myopia

      Explore m2.healio.com Ophthalmology
      Small Hyperreflective Intraretinal Material Observable on Spectral-Domain Optical Coherence Tomography in High Myopia
      With the rapid adoption of spectraldomain optical coherence tomography (SD-OCT) in clinical practice and recent advances in technology, SD-OCT has become an important tool for detecting and managing retinal pathology. The diagnosis of degenerative changes in pathologic myopia can sometimes be difficult and delayed, as the clinical presentation may be subtle. In this series, SD-OCT proved useful in the detection of small hyperreflective intraretinal material in cases in which retinal ...
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      Mentions: Northwestern University

    13. RESIDUAL CHOROIDAL VESSELS IN ATROPHY CAN MASQUERADE AS CHOROIDAL NEOVASCULARIZATION ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Introducing a Clinical and Software Approach

      Explore LWW Online Ophthalmology
      RESIDUAL CHOROIDAL VESSELS IN ATROPHY CAN MASQUERADE AS CHOROIDAL NEOVASCULARIZATION ON OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY: Introducing a Clinical and Software Approach
      Purpose: To present a postprocessing approach in optical coherence tomography angiography (OCTA) to facilitate the visualization and interpretation of lesions in age-related macular degeneration with coexisting atrophy and choroidal neovascularization (CNV). Methods: This retrospective study included 32 eyes of 26 patients with atrophy and treated CNV and 8 eyes with treatment-naive geographic atrophy. En face optical coherence tomography slabs highlighting atrophy were pseudocolored and merged with the corresponding OCTA. Cross-sectional ...
      Read Full Article
      Mentions: Northwestern University

    14. OCT Angiography Imaging in Serpiginous Choroidopathy

      Explore Ophthalmology Retina Ophthalmology
      OCT Angiography Imaging in Serpiginous Choroidopathy
      Purpose To report OCTA findings in 3 cases, 2 active and 1 inactive, of serpiginous choroidopathy (SC) and describe OCTA changes in response to treatment. Design Retrospective case series. Participants We studied 6 eyes of 3 patients with SC. Methods Retrospective case series of 3 patients with SC undergoing multimodal imaging, including OCTA. In 1 treated eye, both pre- and posttreatment images were compared. Main Outcome Measures Description of OCTA ...
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      Mentions: Northwestern University

    15. Spectroscopic Doppler analysis for visible-light optical coherence tomography

      Explore SPIE Digital Library
      Spectroscopic Doppler analysis for visible-light optical coherence tomography
      Retinal oxygen metabolic rate can be effectively measured by visible-light optical coherence tomography (vis-OCT), which simultaneously quantifies oxygen saturation and blood flow rate in retinal vessels through spectroscopic analysis and Doppler measurement, respectively. Doppler OCT relates phase variation between sequential A-lines to the axial flow velocity of the scattering medium. The detectable phase shift is between and due to its periodicity, which limits the maximum measurable unambiguous velocity without phase ...
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      Mentions: Northwestern University Hao F. Zhang

    16. Opticent Receives NIH Grant for Method for Accurate Retinal Oxygen Metabolic Rate Extraction

      Explore Optical Coherence Tomography News Ophthalmology , Funding
      Opticent Receives NIH Grant for Method for Accurate Retinal Oxygen Metabolic Rate Extraction
      ... has the potential to significantly improve the management of proliferative DR. Prof. Hao F. Zhang’s group at Northwestern University demonstrated in 2013 that visible light optical coherence tomography (vis-OCT) can acc...
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      Mentions: National Institutes of Health Northwestern University Hao F. Zhang
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  4. About Northwestern University

    Northwestern University

    Northwestern University is a private research university located in Evanston, Illinois and downtown Chicago, Illinois.  Several of Northwestern's professional schools such as the School of Law, the Feinberg School of Medicine, and parts of the Kellogg School of Management are located in the Streeterville neighborhood of downtown Chicago. 

    Biophotonics Laboratory at Northwestern University.  The main direction of the Biophotonics laboratory (Principal Investigator: Prof. Vadim Backman) is the development of novel optical spectral and imaging techniques for non-invasive screening, diagnosis and detection of disease as well as characterization of biological and bioengineered tissue.

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