1. Nizhny Novgorod State Medical Academy

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    1. Mentioned In 61 Articles

    2. Speckle statistics in OCT images: Monte Carlo simulations and experimental studies

      Speckle statistics in OCT images: Monte Carlo simulations and experimental studies
      The speckle pattern of an optical coherence tomography (OCT) image carries potentially useful sample information that may assist in tissue characterization. Recent biomedical resultsin vivoindicate that the distribution of signal intensities within an OCT tissue image is well described by a log-normal-like (Gamma) function. To fully understand and exploit this finding, an OCT Monte Carlo model that accounts for speckle effects was developed. The resultant Monte Carlo speckle statistics predictions ...
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    3. Combining the correlation-stability approach to OCT elastography with the speckle-variance evaluation for quantifying the stiffness differences

      Combining the correlation-stability approach to OCT elastography with the speckle-variance evaluation for quantifying the stiffness differences
      We discuss an advanced variant of the correlation-stability (CS) approach to OCT elastography that is capable of quantifying the stiffness differences. The modified variant is based on natural combination of CS approach with the speckle-variance (SV) approach. It allows one to determine the strain dependence of the normalized speckle intensity variance function for two compared subsets taken from the OCT images corresponding to the initial and deformed states of the ...
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    4. Towards free-hand implementation of OCT elastography: displacement-based approaches versus correlation-stability ones

      Towards free-hand implementation of OCT elastography: displacement-based approaches versus correlation-stability ones
      In this report, we present a comparative discussion of a recently proposed method of elastographic mapping based on comparison of correlation stability (CS) of different parts of sequentially obtained OCT images of the strained tissue and more conventional correlation approaches to elastographic mapping based on the initial reconstruction of the displacement field. The performed study is based on numerical simulations of speckle patterns generated by reproducing main features of image ...
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    5. Method of optical coherence tomography with parallel depth-resolved signal reception and fibre-optic phase modulators

      Method of optical coherence tomography with parallel depth-resolved signal reception and fibre-optic phase modulators
      The method of optical coherence tomography with the scheme of parallel reception of the interference signal (P-OCT) is developed on the basis of spatial paralleling of the reference wave by means of a phase diffraction grating producing the appropriate time delay in the MachZehnder interferometer. The absence of mechanical variation of the optical path difference in the interferometer essentially reduces the time required for 2D imaging of the object internal ...
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    6. Elastographic mapping in optical coherence tomography using an unconventional approach based on correlation stability

      Elastographic mapping in optical coherence tomography using an unconventional approach based on correlation stability
      An approach to elastographic mapping in optical coherence tomography (OCT) using comparison of correlation stability of sequentially obtained intensity OCT images of the studied strained tissue is discussed. The basic idea is that for stiffer regions, the OCT image is distorted to a smaller degree. Consequently, cross-correlation maps obtained with compensation of trivial translational motion of the image parts using a sliding correlation window can represent the spatial distribution of ...
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    7. Morphological changes in skin of different phototypes under the action of topical corticosteroid therapy and tacrolimus

      Morphological changes in skin of different phototypes under the action of topical corticosteroid therapy and tacrolimus
      ...steroid therapy and tacrolimus. Skin Research and Technology. doi: 10.1111/srt.12095 Author Information 1. ^1 Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia 2. ^2 Institute of Applied Physics of RAS, Nizh...
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    8. Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers

      Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers
      The combined use of fluorescence cystoscopy and cross-polarization optical coherence tomography (CP OCT) with quantitative estimation of the OCT signal was assessed in 92 bladder zones. It demonstrated the diagnostic accuracy in detecting superficial bladder cancer of 93.6%, sensitivity 96.4%, specificity 92.1%, positive predictive value 87% and negative predictive value 97.9%. Quantitative estimation of OCT signal standard deviation in cross-polarization (CP OCT SD index) makes the ...
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    9. Dual instrument for in vivo and ex vivo OCT imaging in an ENT department

      Dual instrument for in vivo and ex vivo OCT imaging in an ENT department
      A dual instrument is assembled to investigate the usefulness of optical coherence tomography (OCT) imaging in an ear, nose and throat (ENT) department. Instrument 1 is dedicated to in vivo laryngeal investigation, based on an endoscope probe head assembled by compounding a miniature transversal flying spot scanning probe with a commercial fiber bundle endoscope. This dual probe head is used to implement a dual channel nasolaryngeal endoscopy-OCT system. The two ...
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    10. Feature Of The Week 9/16/12: Institute of Applied Physics/Russian Academy of Sciences Investigates Criteria for Pathology Recognition in Optical Coherence Tomography of Fallopian Tubes

      Feature Of The Week 9/16/12: Institute of Applied Physics/Russian Academy of Sciences Investigates Criteria for Pathology Recognition in Optical Coherence Tomography of Fallopian Tubes
      The problems of revealing causes of infertility and chronic pelvic pains are currently of great significance. The World Health Organization (WHO) reports on the level of infertile marriages which grew up to 12-18% worldwide in the recent 2-3 decades and its classification includes unexplained infertility, when there are no visible objective causes of impairment of reproductive function. On the one hand, unexplained infertility is associated with prevalence of asymptomatic and ...
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    11. Evaluation of oral mucosa collagen condition with cross-polarization optical coherence tomography

      Evaluation of oral mucosa collagen condition with cross-polarization optical coherence tomography
      The goal of the research was analysis of the effect of collagen condition in formation of cross-polarized CP OCT images. We used of the CP OCT technique for studying collagen condition on an example of oral mucosa. Special histologic picrosirius red (PSR) staining of cheek mucosa specimens was used with subsequent assessing of the result of collagen staining in polarized light. High correlation (r = 0.692, p = 0.0001) between ...
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    12. Complex assessment of age-specific morphofunctional features of skin of different anatomic localizations

      Complex assessment of age-specific morphofunctional features of skin of different anatomic localizations
      ...c localizations. Skin Research and Technology. doi: 10.1111/j.1600-0846.2012.00613.x Author Information 1. ^1 Nizhny Novgorod State Medical Academy, Nizhny Novgorod, Russia 2. ^2 Institute of Applied Physics of RAS, Nizh...
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    13. Laser hyperthermia of tumors using gold nanoparticles monitored by optical coherence tomography and acoustic thermometry

      Laser hyperthermia of tumors using gold nanoparticles monitored by optical coherence tomography and acoustic thermometry
      Local laser hyperthermia of grafted RShM-5 tumors in mice with the use of plasmon resonant gold nanoparticles has been carried out. Accumulation of particles in the tumor was monitored in vivo noninvasively by optical coherence tomography. Thereby it was determined that the maximal content of nanoparticles in the tumor was reached within 5 h after intravenous administration, and laser hyperthermia was performed at this time. Monitoring the tumor temperature during ...
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    14. OCT in difficult diagnostic cases in gynecology

      OCT in difficult diagnostic cases in gynecology
      The study is aimed at developing new methods for diagnosing causes of impairment of female reproductive function. An increase of infertility and chronic pelvic pains syndrome, a growing level of latent diseases of this group, as well as a stably high percentage (up to 25% for infertility and up to 60% for the chronic pelvic pains syndrome) of undetermined origin make this research extremely important. As a complementary technique to ...
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    15. Mechanical compression for contrasting OCT images of biotissues

      Mechanical compression for contrasting OCT images of biotissues
      Contrasting of biotissue layers in OCT images after application of mechanical compression is discussed. The study is performed on ex vivo samples of human rectum, and in vivo on skin of human volunteers. We show that mechanical compression provides contrasting of biotissue layer boundaries due to different mechanical properties of layers. We show that alteration of pressure from 0 up to 0.45 N/mm2 causes contrast increase from 1 ...
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    16. Feature Of The Week 3/13/11: Russian Scientists Investigate Cross Polarization OCT for Early Bladder Cancer Detection

      Feature Of The Week 3/13/11: Russian Scientists Investigate Cross Polarization OCT for Early Bladder Cancer Detection
      ...dder cancer detection.  The work is from the prestigious Institute of Applied and Fundamental Medicine at the Nizhny Novgorod State Medical Academy and the Institute of Applied Physics of the Russian Academy of Sciences,...
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    17. 31-45 of 61 « 1 2 3 4 »
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  2. About Nizhny Novgorod State Medical Academy

    Nizhny Novgorod State Medical Academy

    Nizhny Novgorod State Medical Academy is one of the medical schools in Russia which is located in the city of Nizhny Novgorod. This medical school is currently ranked number 7 out of 46 higher medical institutions in Russia, acknowledged by World Health Organization and is recognized by the governments of some other countries which send their students to this academy for medical education and training. This academy also is associated with many teaching hospitals distributed throughout the city, where the students learn many basic clinical skills. The administrative office of the academy is situated in Minin and Pozharsky Square (located alongside the Volga River and the medical students live in dormitories on Meditsinskaya Street in Prioksky City District.