1. Nienke Bosschaart

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    1. Mentioned In 8 Articles

    2. Spatially confined quantification of bilirubin concentrations by spectroscopic visible-light optical coherence tomography

      Spatially confined quantification of bilirubin concentrations by spectroscopic visible-light optical coherence tomography
      Spatially confined measurements of bilirubin in tissue can be of great value for noninvasive bilirubin estimations during neonatal jaundice, as well as our understanding of the physiology behind bilirubin extravasation. This work shows the potential of spectroscopic visible-light optical coherence tomography (sOCT) for this purpose. At the bilirubin absorption peak around 460 nm, sOCT suffers from a strong signal decay with depth, which we overcome by optimizing our system sensitivity ...
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    3. Validation of quantitative attenuation and backscattering coefficient measurements by optical coherence tomography in the concentration-dependent and multiple scattering regime

      Validation of quantitative attenuation and backscattering coefficient measurements by optical coherence tomography in the concentration-dependent and multiple scattering regime
      Optical coherence tomography (OCT) has the potential to quantitatively measure optical properties of tissue such as the attenuation coefficient and backscattering coefficient. However, to obtain reliable values for strong scattering tissues, accurate consideration of the effects of multiple scattering and the nonlinear relation between the scattering coefficient and scatterer concentration (concentration-dependent scattering) is required. We present a comprehensive model for the OCT signal in which we quantitatively account for both ...
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    4. Quantitative comparison of analysis methods for spectroscopic optical coherence tomography: reply to comment

      Quantitative comparison of analysis methods for spectroscopic optical coherence tomography: reply to comment
      ...pectroscopic optical coherence tomography,” Biomed. Opt. Express4(11), 2570–2584 (2013). [CrossRef] [PubMed] N. Bosschaart, T. G. van Leeuwen, M. C. G. Aalders, and D. J. Faber, “Quantitative comparison of analysis meth...
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    5. In vivo low-coherence spectroscopic measurements of local hemoglobin absorption spectra in human skin

      In vivo low-coherence spectroscopic measurements of local hemoglobin absorption spectra in human skin
      ...ts of absorption spectra in scattering media by low-coherence spectroscopy,” Opt. Lett. 34, 3746–3748 (2009). N. Bosschaart, D. J. Faber, T. G. van Leeuwen, and M. C. G. Aalders, “Measurements of wavelength dependent sca...
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    6. Optical properties of neonatal skin measured in vivo as a function of age and skin pigmentation

      Optical properties of neonatal skin measured in vivo as a function of age and skin pigmentation
      ..., but a strong dependency of the absorption coefficient on postnatal age was found for dark skinned patients. Nienke Bosschaart, Rosaline Mentink, Joke H. Kok, Ton G. van Leeuwen and Maurice C. G. Aalders, "Optical prope...
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    7. Combined Raman spectroscopy and optical coherence tomography device for tissue characterization

      Combined Raman spectroscopy and optical coherence tomography device for tissue characterization
      ...ipt Accepted: April 14, 2008 Revised Manuscript: April 11, 2008 Published: May 14, 2008 Citation C. A. Patil, N. Bosschaart, M. D. Keller, T. G. van Leeuwen, and A. Mahadevan-Jansen, "Combined Raman spectroscopy and opti...
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  2. About Nienke Bosschaart

    Nienke Bosschaart

    Nienke Bosschaart is at the University of Amsterdam Academic Medical Center in The Netherlands.