1. Nicolaus Copernicus University

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    1. Mentioned In 183 Articles

    2. Non-contact investigation of the corneal biomechanics with air-puff swept source optical coherence tomography

      Non-contact investigation of the corneal biomechanics with air-puff swept source optical coherence tomography
      In this paper, we use swept source optical coherence tomography combined with air-puff module (air-puff SS-OCT) to investigate the properties of the cornea. During OCT measurement the cornea was stimulated by short, air pulse, and corneal response was recorded. In this preliminary study, the air-puff SS-OCT instrument was applied to measure behavior of the porcine corneas under varied, well-controlled intraocular pressure conditions. Additionally, the biomechanical response of the corneal tissue ...
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    3. Coherence properties of fast frequency swept lasers revealed via full electric field reconstruction

      Coherence properties of fast frequency swept lasers revealed via full electric field reconstruction
      A novel, time-resolved interferometric technique is presented allowing the reconstruction of the complex electric field output of a fast frequency swept laser in a single-shot measurement. The power of the technique is demonstrated by examining a short cavity swept source designed for optical coherence tomography applications, with a spectral bandwidth of 18 THz. This novel analysis of the complete electric field reveals the modal structure and modal evolution of the ...
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    4. Imaging of the stroke-related changes in the vascular system of the mouse brain with the use of extended focus Optical Coherence Microscopy

      Imaging of the stroke-related changes in the vascular system of the mouse brain with the use of extended focus Optical Coherence Microscopy
      We used Optical Coherence Microscopy (OCM) to monitor structural and functional changes due to ischemic stroke in small animals brains in vivo. To obtain lateral resolution of 2.2 m over the range of 600 m we used extended focus configuration of OCM instrument involving Bessel beam. It provided access to detailed 3D information about the changes in brain vascular system up to the level of capillaries across I and ...
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    5. Tissue thickness calculation in ocular optical coherence tomography

      Tissue thickness calculation in ocular optical coherence tomography
      Thickness measurements derived from optical coherence tomography (OCT) images of the eye are a fundamental clinical and research metric, since they provide valuable information regarding the eyes anatomical and physiological characteristics, and can assist in the diagnosis and monitoring of numerous ocular conditions. Despite the importance of these measurements, limited attention has been given to the methods used to estimate thickness in OCT images of the eye. Most current studies ...
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    6. On the application of Optical Coherence Tomography as a complimentary tool in a analysis of the 13th century Byzantine Bessarion Reliquary

      On the application of Optical Coherence Tomography as a complimentary tool in a analysis of the 13th century Byzantine Bessarion Reliquary
      This work presents the results of an application of Optical Coherence Tomography (OCT) to examination a 13th century Byzantine reliquary of unparalleled artistic and historical value. The aim of this work, performed at the initial stage, before the restoration, was focused on the resolution of cleaning procedures regarding both the thick, old varnish and the gold leaf details finely applied on the painted parts of the artwork by means of ...
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    7. Optical Coherence Tomography of the Labial Salivary Glands Reveals Age-Related Differences in Women

      Optical Coherence Tomography of the Labial Salivary Glands Reveals Age-Related Differences in Women
      The labial minor salivary glands (LSGs) play a role in medical research and practice due to their superficial location and involvement in both systemic and localized diseases. Swept-source optical coherence tomography (OCT) is a noninvasive modality that enables in vivo , micrometer resolution, wide-field three-dimensional imaging in seconds. A purpose-built swept-source OCT instrument was employed to acquire three-dimensional datasets covering the area of 2.43 cm 2 of the mucosa of ...
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    8. Differentiation of morphotic elements in human blood using optical coherence tomography and a microfluidic setup

      Differentiation of morphotic elements in human blood using optical coherence tomography and a microfluidic setup
      We demonstrate a novel optical method for the detection and differentiation between erythrocytes and leukocytes that uses amplitude and phase information provided by optical coherence tomography (OCT). Biological cells can introduce significant phase modulation with substantial scattering anisotropy and dominant forward-scattered light. Such physical properties may favor the use of a trans-illumination imaging technique. However, an epi-illumination mode may be more practical and robust in many applications. This study describes ...
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    9. The application of macro-X-ray fluorescence and optical coherence tomography for examination of parchment manuscripts

      The application of macro-X-ray fluorescence and optical coherence tomography for examination of parchment manuscripts
      Macro-X-ray fluorescence (XRF) is a newly commercially available research tool very useful in the examination of artwork. Its novelty lies in its ability to create maps of the distribution of chemical elements on scales of a few milimetres. In this contribution, its use together with optical coherence tomography (OCT) in the inspection of an illuminated manuscript is reported for the first time. The former technique is used both for mapping ...
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    10. Blue-light Fourier-domain optical-coherence microscopy with linear k-sampling using second-harmonic generation

      Blue-light Fourier-domain optical-coherence microscopy with linear k-sampling using second-harmonic generation
      We demonstrate Fourier-domain optical-coherence microscopy (OCM) method that uses blue light for high-resolution microscopic imaging. Spectrally broad bandwidth is obtained by means of second-harmonic generation of Ti:sapphire laser light on the nonlinear crystal. Angular scanning of the crystal performed by a resonant scanner results in second-harmonic generation for a broad range of frequencies producing blue light with central wavelength of 402 nm and bandwidth of 35 nm in one ...
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    11. Spectroscopy by joint spectral and time domain optical coherence tomography

      Spectroscopy by joint spectral and time domain optical coherence tomography
      We present the methodology for spectroscopic examination of absorbing media being the combination of Spectral Optical Coherence Tomography and Fourier Transform Spectroscopy. The method bases on the joint Spectral and Time OCT computational scheme and simplifies data analysis procedure as compared to the mostly used windowing-based Spectroscopic OCT methods. The proposed experimental setup is self-calibrating in terms of wavelength-pixel assignment. The performance of the method in measuring absorption spectrum was ...
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    12. Wavelength to pixel calibration for FdOCT

      Wavelength to pixel calibration for FdOCT
      We show that in Fourier domain Optical Coherence Tomography (FdOCT) it is possible to determine the wavelength of light for each point of the detected spectrum using any measurable physical quantity that has linear dependency on wavenumber. The presented approach is robust as the actual values of the measured quantity have no importance for the algorithm. As example we calibrate a SOCT spectrometer using Doppler frequency induced in time-dependent spectral ...
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    13. 46-60 of 183 « 1 2 3 4 5 6 7 ... 11 12 13 »
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  2. About Nicolaus Copernicus University

    Nicolaus Copernicus University

    Nicolaus Copernicus University (NCU) founded in Torun in 1945 is one of the biggest academic institutions in Poland with the total number of 14 divisions, 54 faculties and 40.000 students. The Medical Physics Group is part of the Institute of Physics of the Nicolaus Copernicus University.  Department of Biophysics and Medical Physics at the Nicolaus Copernicus University.  The department members use both experimental (optics and optical spectroscopy) and theoretical (quantum chemistry and molecular dynamics) methods to investigate the structure and dynamic of biologically relevant molecules and tissues.  Nicolaus Copernicus University Collegium Medicum is the Medical College of NCU.