1. Nicolaus Copernicus University

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    1. Mentioned In 171 Articles

    2. In vivo volumetric imaging by crosstalk-free full-field OCT

      In vivo volumetric imaging by crosstalk-free full-field OCT
      Cellular resolution imaging of biological structures has always been a challenge due to strong scattering that limits the achievable transverse resolution or imaging penetration depth. Recently, a major advancement toward high-resolution and volumetric imaging was achieved by implementing a parallel detection (i.e., full field) into Fourier-domain optical coherence tomography. The drawback of using parallel detection is that scattered light can travel laterally and get mapped improperly at a camera ...
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    3. Air-Puff-Induced Dynamics of Ocular Components Measured with Optical Biometry

      Air-Puff-Induced Dynamics of Ocular Components Measured with Optical Biometry
      Purpose : To analyze the dynamics of all optical components of the eye and the behavior of the eyeball under air-puff conditions in vivo. To determine the impact of the intraocular pressure (IOP) on the air-puff-induced deformation of the eye. Methods : Twenty eyes of 20 healthy subjects were included in this study. The dynamics of the ocular components, such as the cornea, the crystalline lens, and the retina, was measured by ...
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    4. Spatiotemporal optical coherence (STOC) manipulation suppresses coherent cross-talk in full-field swept-source optical coherence tomography

      Spatiotemporal optical coherence (STOC) manipulation suppresses coherent cross-talk in full-field swept-source optical coherence tomography
      Full-field swept-source optical coherence tomography (FF-SS-OCT) provides high-resolution depth-resolved images of the sample by parallel Fourier-domain interferometric detection. Although FF-SS-OCT implements high-speed volumetric imaging, it suffers from the cross-talk-generated noise from spatially coherent lasers. This noise reduces the transversal image resolution, which in turn, limits the wide adaptation of FF-SS-OCT for practical and clinical applications. Here, we introduce the novel spatiotemporal optical coherence (STOC) manipulation. In STOC the time-varying inhomogeneous ...
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    5. Computationally effective 2D and 3D fast phase unwrapping algorithms and their applications to Doppler optical coherence tomography

      Computationally effective 2D and 3D fast phase unwrapping algorithms and their applications to Doppler optical coherence tomography
      We propose a simplification for a robust and easy to implement fast phase unwrapping (FPU) algorithm that is used to solve the phase wrapping problem encountered in various fields of optical imaging and metrology. We show that the number of necessary computations using the algorithm can be reduced compared to its original version. FPU can be easily extended from two to three spatial dimensions. We demonstrate the applicability of the ...
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    6. A Micro-Tomographic Insight into the Coating Systems of Historical Bowed String Instruments

      A Micro-Tomographic Insight into the Coating Systems of Historical Bowed String Instruments
      Musical instruments are tools for playing music, but for some of themmade by the most important historical violin makersthe myths hide the physical artwork. Ancient violin-making Masters developed peculiar construction methods and defined aesthetic canons that are still recognizable in their musical instruments. Recently, the focus of scientific investigations has been set on the characterization of materials and methods used by the ancient violin makers by means of several scientific ...
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    7. Optical Coherence Tomography (OCT) for Examination of Artworks (Book Chapter)

      Optical Coherence Tomography (OCT) for Examination of Artworks (Book Chapter)
      his book details the application of advanced characterisation techniques and diagnostic tools to heritage science, including the evaluation of heritage assets condition, their preservation and restoration. It examines the use of electrochemical techniques in conservation science, with a particular focus on how to solve problems in taking on-site measurements. Specifically, it introduces readers to a new gel polymer (GPE) electrochemical cell developed by the authors for the characterisation of metallic ...
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    8. Optical Coherence Tomography (OCT) for Examination of Artworks (Book Chapter)

      Optical Coherence Tomography (OCT) for Examination of Artworks (Book Chapter)
      Optical coherence tomography is a fast, non-invasive technique of structural analysis utilising near-infrared radiation. Examples of using OCT, for obtaining cross-sectional images of objects of craftsmanship and an easel painting have been shown. Issues regarding the technique of execution and destruction phenomena were resolved non-invasively. In some cases, the secondary alterations can be identified and localised within the objects structure which helps in authentication of the artwork.
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    9. Megahertz-rate optical coherence tomography angiography improves the contrast of the choriocapillaris and choroid in human retinal imaging

      Megahertz-rate optical coherence tomography angiography improves the contrast of the choriocapillaris and choroid in human retinal imaging
      Angiographic imaging of the human eye with optical coherence tomography (OCT) is becoming an increasingly important tool in the scientific investigation and clinical management of several blinding diseases, including age-related macular degeneration and diabetic retinopathy. We have observed that OCT angiography (OCTA) of the human choriocapillaris and choroid with a 1.64 MHz A-scan rate swept-source laser yields higher contrast images as compared to a slower rate system operating at ...
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    10. Intraframe motion correction for raster-scanned adaptive optics images using strip-based cross-correlation lag biases

      Intraframe motion correction for raster-scanned adaptive optics images using strip-based cross-correlation lag biases
      In retinal raster imaging modalities, fixational eye movements manifest as image warp, where the relative positions of the beam and retina change during the acquisition of single frames. To remove warp artifacts, strip-based registration methodsin which fast-axis strips from target images are registered to a reference framehave been applied in adaptive optics (AO) scanning light ophthalmoscopy (SLO) and optical coherence tomography (OCT). This approach has enabled object tracking and frame ...
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    11. Non invasive optical cellular imaging in humans

      Non invasive optical cellular imaging in humans
      One of the most appealing and still unsolved problems in biological and medical imaging is the possibility of noninvasive visualization of tissue in vivo with an accuracy of microscopic examination. A major difficulty to solve in biomedical imaging is a degradation of image quality caused by the presence of optical inhomogeneity of tissue. Is there any chance to develop a microscopic method that allows non-invasive observation of cells in living ...
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    12. Enhancing microvasculature maps for Optical Coherence Tomography - Angiography (OCT-A)

      Enhancing microvasculature maps for Optical Coherence Tomography - Angiography (OCT-A)
      OCT-A is becoming more popular in recent years and there is a high demand to improve the quality of angiograms as well as to extract quantitative information. We applied various processing methods for microvasculature enhancement like Hessian-Frangi to a data set obtained with Bessel and Gaussian OCT systems. We used angiogenesis, fractal and multifractal analysis to extract more quantitative information. We applied the processing methods for healthy, stroke, tumor progression ...
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    13. Assessment of the influence of viscoelasticity of cornea in animal ex vivo model using air‐puff optical coherence tomography and corneal hysteresis

      Assessment of the influence of viscoelasticity of cornea in animal ex vivo model using air‐puff optical coherence tomography and corneal hysteresis
      Application of the air‐puff swept source OCT (SS‐OCT) instrument to determine the influence of viscoelasticity on the relation between overall the air‐puff force and corneal apex displacement of porcine corneas ex vivo is demonstrated. Simultaneous recording of time‐evolution of the tissue displacement and air pulse stimulus allows obtaining valuable information related in part to the mechanical properties of the cornea. A novel approach based on quantitative ...
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    14. Post-doctoral Research Fellow Position and 2 PhD Studentships in Ophthalmic Imaging at the Nicolaus Copernicus University, Torun, Poland

      Post-doctoral Research Fellow Position and 2 PhD Studentships in Ophthalmic Imaging at the Nicolaus Copernicus University, Torun, Poland
      ...e project and application details: igrulkowski@fizyka.umk.pl  The Bio-Optics & Optical Engineering Lab at the Nicolaus Copernicus University invites applications for the positions in a project entitled Lenticular and vit...
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    15. Volumetric macro- and micro-scale assessment of crystalline lens opacities in cataract patients using long-depth-range swept source optical coherence tomography

      Volumetric macro- and micro-scale assessment of crystalline lens opacities in cataract patients using long-depth-range swept source optical coherence tomography
      We demonstrate an optimized optical platform for the three-dimensional (3-D) visualization of crystalline lens opacities in vivo in the eyes of patients with different types and grades of cataracts. We developed a prototype long-depth-range swept source optical coherence tomography (SS-OCT) instrument operating at the speed of 50 kA-scans/second and at the central wavelength of 1 m to perform high-resolution imaging of the whole anterior segment of the eye. Volumetric ...
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  2. About Nicolaus Copernicus University

    Nicolaus Copernicus University

    Nicolaus Copernicus University (NCU) founded in Torun in 1945 is one of the biggest academic institutions in Poland with the total number of 14 divisions, 54 faculties and 40.000 students. The Medical Physics Group is part of the Institute of Physics of the Nicolaus Copernicus University.  Department of Biophysics and Medical Physics at the Nicolaus Copernicus University.  The department members use both experimental (optics and optical spectroscopy) and theoretical (quantum chemistry and molecular dynamics) methods to investigate the structure and dynamic of biologically relevant molecules and tissues.  Nicolaus Copernicus University Collegium Medicum is the Medical College of NCU.