1. Nicolaus Copernicus University

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    1. Mentioned In 191 Articles

    2. Munch and optical coherence tomography: unravelling historical and artist applied varnish layers in painting collections

      Munch and optical coherence tomography: unravelling historical and artist applied varnish layers in painting collections
      Effective care of large-scale museum collections requires planning that includes the conservation treatment of specific groups of art works, such as appropriate cleaning strategies. Optical coherence tomography (OCT) has been successfully applied as a non-invasive method for the stratigraphic visualisation of the uppermost transparent and semi-transparent layers in paintings, such as varnishes. Several OCT case study examples have further demonstrated the capabilities of the non-contact interferometric technique to measure the ...
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    3. Spatio-Temporal Optical Coherence Tomography provides advanced imaging of the human retina and choroid

      Spatio-Temporal Optical Coherence Tomography  provides advanced imaging of the human retina and choroid
      One of the greatest needs in modern ophthalmology is access to the eyes choroid in vivo. Without it, it is difficult to introduce new therapies and to understand most of the pathological changes in the eye, because 85% of the total blood flow in the eye i s caused by the choroidal circulation. It is entirely responsible for the metabolism of photoreceptors, which each of us feels every day and ...
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    4. Volumetric Optical Imaging and Quantitative Analysis of Age-Related Changes in Anterior Human Vitreous

      Volumetric Optical Imaging and Quantitative Analysis of Age-Related Changes in Anterior Human Vitreous
      Purpose : The purpose of this study was to characterize age-related changes in anterior human vitreous with 3-D swept source optical coherence tomography (SS-OCT) and evaluate associations with axial length (AL) and contrast sensitivity function (CSF). Methods : There were 49 phakic eyes in 49 patients (40.0 19.3 years) had 3-D volumetric scanning of the lens and retrolental vitreous with SS-OCT at 1050 nm. OCT-derived indices of vitreous optical density ...
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    5. Whole anterior segment and retinal swept source OCT for comprehensive ocular screening

      Whole anterior segment and retinal swept source OCT for comprehensive ocular screening
      Whole eye visualization and morphometry are of high relevance in clinical practice. However, most standard ophthalmic OCT instruments are dedicated either to retinal or to anterior segment imaging. We demonstrate a swept source optical coherence tomography system (SS-OCT) that images both the whole anterior segment and the retina alternately using a single source and detector. A pilot population was imaged with the proof of concept prototype. We demonstrate the clinical ...
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    6. Non-invasive Survey of Rubens’ Ceiling Paintings at the Banqueting House Whitehall, London, by Means of Optical Coherence Tomography

      Non-invasive Survey of Rubens’ Ceiling Paintings at the Banqueting House Whitehall, London, by Means of Optical Coherence Tomography
      This article presents the results of the examination by means of optical coherence tomography (OCT) of two of the nine monumental ceiling paintings by Peter Paul Rubens and his studio, still located in their original location at the Banqueting House, the only surviving building of the former Whitehall Palace in London. OCT is a non-invasive technique of structural imaging of layers semi-permeable to infrared light. The aim of the 2018 ...
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    7. Fourier domain quantum optical coherence tomography

      Fourier domain quantum optical coherence tomography
      Quantum optical coherence tomography (Q-OCT) is the non-classical counterpart of optical coherence tomography (OCT), a high-resolution 3D imaging technique based on white-light interferometry. Because Q-OCT uses a source of frequency-entangled photon pairs, not only is the axial resolution not affected by dispersion mismatch in the interferometer but is also inherently improved by a factor of two. Unfortunately, practical applications of Q-OCT are hindered by image-scrambling artefacts and slow acquisition times ...
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    8. In vivo SS-OCT imaging of crystalline lens sutures

      In vivo SS-OCT imaging of crystalline lens sutures
      We demonstrate in vivo three-dimensional (3-D) visualization of crystalline lens sutures in healthy eyes using swept source optical coherence tomography (SS-OCT). Volumetric data sets of the crystalline lenses were acquired and processed to obtain enhanced contrast projection images and to extract suture patterns in both anterior and posterior lens. The results presented different types of the sutures including Y-sutures, simple and complex star sutures. Age-related changes in suture arrangement were ...
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    9. Correlation of retinal sensitivity in microperimetry with vascular density in optical coherence tomography angiography in primary open-angle glaucoma

      Correlation of retinal sensitivity in microperimetry with vascular density in optical coherence tomography angiography in primary open-angle glaucoma
      Purpose To evaluate the correlation between retinal sensitivity in microperimetry (MP) with vessel density (VD) using optical coherence tomography angiography (OCTA) in primary open-angle glaucoma (POAG). Methods We enrolled 30 participants (52 eyes) with POAG and 15 participants (23 eyes) in the healthy control group. All participants were examined for retinal structure using OCTA to assess VD and Spectral domain OCT (SD-OCT) to assess ganglion cell complex (GCC) and peripapillary ...
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    10. Quantum Optical Coherence Tomography using two photon joint spectrum detection (JS-Q-OCT)

      Quantum Optical Coherence Tomography using two photon joint spectrum detection (JS-Q-OCT)
      Quantum Optical Coherence Tomography (Q-OCT) is the non-classical counterpart of Optical Coherence Tomography (OCT) - a high-resolution 3D imaging technique based on white-light interferometry. Because Q-OCT uses a source of frequency-entangled photon pairs, not only is the axial resolution not affected by dispersion mismatch in the interferometer, but is also inherently improved by a factor of square root of two. Unfortunately, practical applications of QOCT are hindered by image-scrambling artefacts and ...
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    11. Spectral and time domain optical coherence spectroscopy

      Spectral and time domain optical coherence spectroscopy
      We propose a novel method for spectroscopic optical coherence tomography (OCT). This method uses the dependence of the Doppler frequency spectrum on the wavenumber. Controlled modulation of the light in the spectral OCT interferometer allows for an instantaneous depth-resolved reconstruction of the backscattered light spectrum from all depths. The feasibility of the spectroscopic analysis using the proposed scheme was confirmed experimentally.
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    12. Quantum-inspired detection for Spectral Domain Optical Coherence Tomography

      Quantum-inspired detection for Spectral Domain Optical Coherence Tomography
      The intensity levels allowed by safety standards (ANSI or ICNIRP) limit the amount of light that can be used in a clinical setting to image highly scattering or absorptive tissues with Optical Coherence Tomography (OCT). To achieve high-sensitivity imaging at low intensity levels, we adapt a detection scheme - which is used in quantum optics for providing information about spectral correlations of photons - into a standard spectral domain OCT system. This ...
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    13. Blood flow rate estimation in optic disc capillaries and vessels using Doppler optical coherence tomography with 3D fast phase unwrapping

      Blood flow rate estimation in optic disc capillaries and vessels using Doppler optical coherence tomography with 3D fast phase unwrapping
      The retinal volumetric flow rate contains useful information not only for ophthalmo-logy but also for the diagnosis of common civilization diseases such as diabetes, Alzheimer's disease, or cerebrovascular diseases. Non-invasive optical methods for quantitative flow assessment, such as Doppler optical coherence tomography (OCT), have certain limitations. One is the phase wrapping that makes simultaneous calculations of the flow in all human retinal vessels impossible due to a very large ...
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    14. In vivo brain imaging with multimodal optical coherence microscopy in a mouse model of thromboembolic photochemical stroke

      In vivo brain imaging with multimodal optical coherence microscopy in a mouse model of thromboembolic photochemical stroke
      We used a new multimodal imaging system that combines optical coherence microscopy and brightfield microscopy. Using this in vivo brain monitoring approach and cranial window implantation, we three-dimensionally visualized the vascular network during thrombosis, with high temporal (18 s) and spatial (axial, 2.5m; lateral, 2.2m) resolution. We used a modified mouse model of photochemical thromboembolic stroke in order to more accurately parallel human stroke. Specifically, we applied green ...
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  2. About Nicolaus Copernicus University

    Nicolaus Copernicus University

    Nicolaus Copernicus University (NCU) founded in Torun in 1945 is one of the biggest academic institutions in Poland with the total number of 14 divisions, 54 faculties and 40.000 students. The Medical Physics Group is part of the Institute of Physics of the Nicolaus Copernicus University.  Department of Biophysics and Medical Physics at the Nicolaus Copernicus University.  The department members use both experimental (optics and optical spectroscopy) and theoretical (quantum chemistry and molecular dynamics) methods to investigate the structure and dynamic of biologically relevant molecules and tissues.  Nicolaus Copernicus University Collegium Medicum is the Medical College of NCU.