1. Nicolaus Copernicus University

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    1. Mentioned In 197 Articles

    2. The use of optical coherence tomography for skin evaluation in healthy rats - A pilot study

      The use of optical coherence tomography for skin evaluation in healthy rats - A pilot study
      Background: Noninvasive diagnostic techniques allow for morphological and morphometric in vivo evaluation of the skin. Optical coherence tomography (OCT) is a method that allows visualization of dermal structures up to several 100 m with a resolution of 3-7.5 m. Objectives: The aim of the study was the morphological and morphometric assessment of rats' skin using SD-OCT. Animals: Fifteen male Wistar rats, aged 3 and 8 months, weighing 350-450 g ...
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    3. Intraretinal Cysts as a Manifestation of Retinal Angiomatous Proliferation in Optical Coherence Tomography Angiography

      Intraretinal Cysts as a Manifestation of Retinal Angiomatous Proliferation in Optical Coherence Tomography Angiography
      Background and Objectives : Intraretinal cysts are common pathology observed inspectral domain optical coherence tomography (SDOCT) in patients with neovascular form of age-related macular degeneration (AMD). The aim of the study was to determine if the presence of intraretinal cysts is positively correlated with diagnosis of retinal angiomatous proliferation (RAP) in optical coherence tomography angiography (OCTA). Material and Methods : A total of 21 eyes with intraretinal cysts in SDOCT exam (Group1 ...
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    4. Simultaneous Corneal Topography and Epithelial Thickness Mapping from a Single Measurement Using Optical Coherence Tomography

      Simultaneous Corneal Topography and Epithelial Thickness Mapping from a Single Measurement Using Optical Coherence Tomography
      Purpose: To evaluate the performance of corneal epithelial thickness mapping (ETM) and demonstrate simultaneous measurement of ETMs and corneal topography using REVO NX (Optopol Technology, Zawiercie, Poland)-an OCT device for anterior and posterior segment imaging. Methods: One hundred thirty-seven eyes of 137 normal subjects and patients with corneal diseases were recruited to the study. Each subject was scanned with REVO NX. ETMs and corneal topography maps were reconstructed from ...
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    5. Multimode fiber as a tool to reduce cross talk in Fourier-domain full-field optical coherence tomography

      Multimode fiber as a tool to reduce cross talk in Fourier-domain full-field optical coherence tomography
      Fourier-domain full-field optical coherence tomography (FD-FF-OCT) is an emerging tool for high-speed eye imaging. However, cross-talk formation in images limits the imaging depth. To this end, we have recently shown that reducing spatial coherence with a fast deformable membrane can suppress the noise but over a limited axial range and with substantial data processing. Here, we demonstrate that a multimode fiber with carefully chosen parameters enables cross-talk-free imaging over a ...
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    6. Extraction of phase-based optoretinograms (ORG) from serial B-scans acquired over tens of seconds by mouse retinal raster scanning OCT system

      Extraction of phase-based optoretinograms (ORG) from serial B-scans acquired over tens of seconds by mouse retinal raster scanning OCT system
      Several specialized retinal optical coherence tomography (OCT) acquisition and processing methods have been recently developed to allow in vivo probing of light-evoked photoreceptors function, focusing on measurements in individual photoreceptors (rods and cones). Recent OCT investigations in humans and experimental animals have shown that the outer segments in dark-adapted rods and cones elongate in response to the visible optical stimuli that bleach fractions of their visual photopigment. We have previously ...
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    7. Munch and optical coherence tomography: unravelling historical and artist applied varnish layers in painting collections

      Munch and optical coherence tomography: unravelling historical and artist applied varnish layers in painting collections
      Effective care of large-scale museum collections requires planning that includes the conservation treatment of specific groups of art works, such as appropriate cleaning strategies. Optical coherence tomography (OCT) has been successfully applied as a non-invasive method for the stratigraphic visualisation of the uppermost transparent and semi-transparent layers in paintings, such as varnishes. Several OCT case study examples have further demonstrated the capabilities of the non-contact interferometric technique to measure the ...
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    8. Spatio-Temporal Optical Coherence Tomography provides advanced imaging of the human retina and choroid

      Spatio-Temporal Optical Coherence Tomography  provides advanced imaging of the human retina and choroid
      One of the greatest needs in modern ophthalmology is access to the eyes choroid in vivo. Without it, it is difficult to introduce new therapies and to understand most of the pathological changes in the eye, because 85% of the total blood flow in the eye i s caused by the choroidal circulation. It is entirely responsible for the metabolism of photoreceptors, which each of us feels every day and ...
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    9. Volumetric Optical Imaging and Quantitative Analysis of Age-Related Changes in Anterior Human Vitreous

      Volumetric Optical Imaging and Quantitative Analysis of Age-Related Changes in Anterior Human Vitreous
      Purpose : The purpose of this study was to characterize age-related changes in anterior human vitreous with 3-D swept source optical coherence tomography (SS-OCT) and evaluate associations with axial length (AL) and contrast sensitivity function (CSF). Methods : There were 49 phakic eyes in 49 patients (40.0 19.3 years) had 3-D volumetric scanning of the lens and retrolental vitreous with SS-OCT at 1050 nm. OCT-derived indices of vitreous optical density ...
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    10. Whole anterior segment and retinal swept source OCT for comprehensive ocular screening

      Whole anterior segment and retinal swept source OCT for comprehensive ocular screening
      Whole eye visualization and morphometry are of high relevance in clinical practice. However, most standard ophthalmic OCT instruments are dedicated either to retinal or to anterior segment imaging. We demonstrate a swept source optical coherence tomography system (SS-OCT) that images both the whole anterior segment and the retina alternately using a single source and detector. A pilot population was imaged with the proof of concept prototype. We demonstrate the clinical ...
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    11. Non-invasive Survey of Rubens’ Ceiling Paintings at the Banqueting House Whitehall, London, by Means of Optical Coherence Tomography

      Non-invasive Survey of Rubens’ Ceiling Paintings at the Banqueting House Whitehall, London, by Means of Optical Coherence Tomography
      This article presents the results of the examination by means of optical coherence tomography (OCT) of two of the nine monumental ceiling paintings by Peter Paul Rubens and his studio, still located in their original location at the Banqueting House, the only surviving building of the former Whitehall Palace in London. OCT is a non-invasive technique of structural imaging of layers semi-permeable to infrared light. The aim of the 2018 ...
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    12. Fourier domain quantum optical coherence tomography

      Fourier domain quantum optical coherence tomography
      Quantum optical coherence tomography (Q-OCT) is the non-classical counterpart of optical coherence tomography (OCT), a high-resolution 3D imaging technique based on white-light interferometry. Because Q-OCT uses a source of frequency-entangled photon pairs, not only is the axial resolution not affected by dispersion mismatch in the interferometer but is also inherently improved by a factor of two. Unfortunately, practical applications of Q-OCT are hindered by image-scrambling artefacts and slow acquisition times ...
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    13. In vivo SS-OCT imaging of crystalline lens sutures

      In vivo SS-OCT imaging of crystalline lens sutures
      We demonstrate in vivo three-dimensional (3-D) visualization of crystalline lens sutures in healthy eyes using swept source optical coherence tomography (SS-OCT). Volumetric data sets of the crystalline lenses were acquired and processed to obtain enhanced contrast projection images and to extract suture patterns in both anterior and posterior lens. The results presented different types of the sutures including Y-sutures, simple and complex star sutures. Age-related changes in suture arrangement were ...
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    14. Correlation of retinal sensitivity in microperimetry with vascular density in optical coherence tomography angiography in primary open-angle glaucoma

      Correlation of retinal sensitivity in microperimetry with vascular density in optical coherence tomography angiography in primary open-angle glaucoma
      Purpose To evaluate the correlation between retinal sensitivity in microperimetry (MP) with vessel density (VD) using optical coherence tomography angiography (OCTA) in primary open-angle glaucoma (POAG). Methods We enrolled 30 participants (52 eyes) with POAG and 15 participants (23 eyes) in the healthy control group. All participants were examined for retinal structure using OCTA to assess VD and Spectral domain OCT (SD-OCT) to assess ganglion cell complex (GCC) and peripapillary ...
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    15. Quantum Optical Coherence Tomography using two photon joint spectrum detection (JS-Q-OCT)

      Quantum Optical Coherence Tomography using two photon joint spectrum detection (JS-Q-OCT)
      Quantum Optical Coherence Tomography (Q-OCT) is the non-classical counterpart of Optical Coherence Tomography (OCT) - a high-resolution 3D imaging technique based on white-light interferometry. Because Q-OCT uses a source of frequency-entangled photon pairs, not only is the axial resolution not affected by dispersion mismatch in the interferometer, but is also inherently improved by a factor of square root of two. Unfortunately, practical applications of QOCT are hindered by image-scrambling artefacts and ...
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  2. About Nicolaus Copernicus University

    Nicolaus Copernicus University

    Nicolaus Copernicus University (NCU) founded in Torun in 1945 is one of the biggest academic institutions in Poland with the total number of 14 divisions, 54 faculties and 40.000 students. The Medical Physics Group is part of the Institute of Physics of the Nicolaus Copernicus University.  Department of Biophysics and Medical Physics at the Nicolaus Copernicus University.  The department members use both experimental (optics and optical spectroscopy) and theoretical (quantum chemistry and molecular dynamics) methods to investigate the structure and dynamic of biologically relevant molecules and tissues.  Nicolaus Copernicus University Collegium Medicum is the Medical College of NCU.