1. Nico Bruining

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    1. Mentioned In 24 Articles

    2. Coronary calcification as a mechanism of plaque/media shrinkage in vessels treated with bioresorbable vascular scaffold: A multimodality intracoronary imaging study

      Coronary calcification as a mechanism of plaque/media shrinkage in vessels treated with bioresorbable vascular scaffold: A multimodality intracoronary imaging study
      Background and aims Whether coronary calcification is correlated with plaque/media shrinkage (PS) remains unclear. The aim of this study was to assess the relationship between the calcification process and PS, combining serial optical coherence tomography (OCT) and intravascular ultrasound (IVUS) in vessels treated with bioresorbable vascular scaffolds (BVS). Methods In 15 patients (16 vessels), OCT and IVUS images were matched using anatomic landmarks at post-procedure and five years. PS ...
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    3. Serial Assessment of Tissue Precursors and Progression of Coronary Calcification Analyzed by Fusion of IVUS and OCT

      Serial Assessment of Tissue Precursors and Progression of Coronary Calcification Analyzed by Fusion of IVUS and OCT
      Objectives The aim of this study was to assess calcium growth with fused grayscale intravascular ultrasound (IVUS), IVUSvirtual histology, and optical coherence tomography (OCT) from baseline to 5-year follow-up in patients treated with bioresorbable vascular scaffolds. Background IVUS and OCT have individual strengths in assessing plaque composition and volume. Fusion of images obtained using these methods could potentially aid in coronary plaque assessment. Methods Anatomic landmarks and endoluminal radiopaque markers ...
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    4. The impact of Fourier-Domain optical coherence tomography catheter induced motion artefacts on quantitative measurements of a PLLA-based bioresorbable scaffold

      The impact of Fourier-Domain optical coherence tomography catheter induced motion artefacts on quantitative measurements of a PLLA-based bioresorbable scaffold
      Intracoronary Fourier-Domain optical coherence tomography (FD-OCT) enables imaging of the coronary artery within 2-4 seconds, a so far unparalleled speed. Despite such fast data acquisition, cardiac and respiratory motion can cause artefacts due to longitudinal displacement of the catheter within the artery. We studied the influence of longitudinal FD-OCT catheter displacement on serial global lumen and scaffold area measurements in coronary arteries of swine that received PLLA-based bioresorbable scaffolds. In ...
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    5. The diabetes conundrum: despite increasing incidences of coronary disease in diabetic type II patients, their first cathlab presentation is later than expected. Observations from an angiographic and optical coherence tomography study

      The diabetes conundrum: despite increasing incidences of coronary disease in diabetic type II patients, their first cathlab presentation is later than expected.  Observations from an angiographic and optical coherence tomography study
      ...esentation is later than expected Observations from an angiographic and optical coherence tomography study 1. Nico Bruining* 1. Eramus MC, Thoraxcenter, Room Ba-571, Dr. Molewaterplein 40, 3015 GD Rotterdam, The Netherla...
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    6. High-speed intracoronary optical frequency domain imaging: implications for three-dimensional reconstruction and quantitative analysis

      High-speed intracoronary optical frequency domain imaging: implications for three-dimensional reconstruction and quantitative analysis
      AIM: To assess the reproducibility of quantitative analysis of optical frequency domain imaging (OFDI) acquired at different pullback speeds (20, 30, 40 mm/sec), as well as the impact of cardiac motion artefact on three-dimensional (3D) reconstructions. METHODS AND RESULTS: A total of 36 OFDI pullbacks were obtained pre- and post-stent implantation at the pullback speeds of 20, 30 and 40 mm/sec in non-diseased swine coronary arteries. The amount ...
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    7. Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures

      Expert review document part 2: methodology, terminology and clinical applications of optical coherence tomography for the assessment of interventional procedures
      Introduction This document is complementary to an Expert Review Document on Optical Coherence Tomography (OCT) for the study of coronary arteries and atherosclerosis.1 The goal of this companion manuscript is to provide a practical guide framework for the appropriate use and reporting of the novel frequency domain (FD) OCT imaging to guide interventional procedures, with a particular interest on the comparison with intravascular ultrasound (IVUS).1–4 Technique for ...
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    8. Interstudy reproducibility of the second generation, Fourier domain optical coherence tomography in patients with coronary artery disease and comparison with intravascular ultrasound: a study applying automated contour detection

      Interstudy reproducibility of the second generation, Fourier domain optical coherence tomography in patients with coronary artery disease and comparison with intravascular ultrasound: a study applying automated contour detection
      Recently, Fourier domain OCT (FD-OCT) has been introduced for clinical use. This approach allows in vivo, high resolution (15 micron) imaging with very fast data acquisition, however, it requires brief flushing of the lumen during imaging. The reproducibility of such fast data acquisition under intracoronary flush application is poorly understood. To assess the inter-study variability of FD-OCT and to compare lumen morphometry to the established invasive imaging method, IVUS. 18 ...
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    9. Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

      Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation
      ..., Writing Committee Co-Chair, Tom Adriaenssens, MD, Peter Barlis, MD, Hiram G. Bezerra, MD, Brett Bouma, PhD, Nico Bruining, PhD, Jin-man Cho, MD, PhD, Saqib Chowdhary, PhD, Marco A. Costa, MD, PhD, Ranil de Silva, MD, P...
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    10. Feature Of The Week 10/16/11: The Diagnostic Value of Intracoronary Optical Coherence Tomography (OCT)

      Feature Of The Week 10/16/11: The Diagnostic Value of Intracoronary Optical Coherence Tomography (OCT)
      This past summer a paper by one of the world's leading clinical research groups in intracoronary OCT was published on the diagnostic value of OCT in intracoronary imaging. Below is a summary of that work. This article discusses the current diagnostic value of OCT, both in cardiovascular research as well as in potential clinical application. OCT generates intracoronary images with unprecedented image resolution, namely a ten-fold higher image resolution ...
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    11. The diagnostic value of intracoronary optical coherence tomography

      The diagnostic value of intracoronary optical coherence tomography
      Abstract  Optical coherence tomography (OCT) is a novel light-based imaging modality for application in the coronary circulation. Compared to conventional intravascular ultrasound, OCT has a ten-fold higher image resolution. This advantage has seen OCT successfully applied in the assessment of atherosclerotic plaque, stent apposition, and tissue coverage, heralding a new era in intravascular coronary imaging. The present article discusses the diagnostic value of OCT, both in cardiovascular research as well ...
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  2. About Nico Bruining

    Nico Bruining

    Nico Bruining is a scientist working at the Thoraxcenter of the Erasmus MC, Rotterdam, The Netherlands. After studying technical computer science het started working at the catheterization laboratory of the Thoraxcenter in 1985. Since 1993, until today, he is working at the department of experimental and clinical informatics of the Thoraxcenter were his field of interest is mainly cardiovascular image processing. In 1998 he obtained his PhD on the thesis: "Quantitative 3-D echocardiography of the heart and the coronary vessels". Currently, his focus is on multi-modality imaging and the development of quantitative tools to improve research in the area of cardiac disease and atherosclerosis. He is currently chairman of the working group of Computers in Cardiology within the European Society of Cardiology.