1. National Yang-Ming University

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    1. Mentioned In 39 Articles

    2. Optical Coherence Tomography-based Diabetic Macula Edema Screening with Artificial Intelligence

      Optical Coherence Tomography-based Diabetic Macula Edema Screening with Artificial Intelligence
      Background: Optical coherence tomography (OCT) is considered as a sensitive and non-invasive tool to evaluate the macular lesions. In patients with diabetes mellitus (DM), the existence of diabetic macular edema (DME) can cause significant vision impairment and further intravitreal injection (IVI) of anti-vascular endothelial growth factor (VEGF) is needed. However, the increasing number of DM patients makes it a big burden for clinicians to manually determine whether DME exists in ...
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    3. Lymphatic vessel segmentation in optical coherence tomography by adding U-Net-based CNN for artifact minimizatio

      Lymphatic vessel segmentation in optical coherence tomography by adding U-Net-based CNN for artifact minimizatio
      he lymphatic system branches throughout the body to transport bodily fluid and plays a key immune-response role. Optical coherence tomography (OCT) is an emerging technique for the noninvasive and label-free imaging of lymphatic capillaries utilizing low scattering features of the lymph fluid. Here, the proposed lymphatic segmentation method combines U-Net-based CNN, a Hessian vesselness filter, and a modified intensity-thresholding to search the nearby pixels based on the binarized Hessian mask ...
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    4. Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography Angiography in Open-Angle and Angle-Closure Glaucoma

      Optic Disc and Macular Vessel Density Measured by Optical Coherence Tomography Angiography in Open-Angle and Angle-Closure Glaucoma
      There is distinct pathogenesis between primary open-angle glaucoma (POAG) and primary angle-closure glaucoma (PACG). Although elevated intraocular pressure (IOP) is the major risk factor for glaucoma, non-IOP risk factors such as vascular abnormalities and lower systolic/diastolic perfusion pressure may play a role in the pathogenic process. This study aimed to compare the vessel density (VD) in the optic disc and macula using optical coherence tomography angiography (OCTA) between POAG ...
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    5. Correlation of corneal pigmented arc with wide epithelial thickness map in orthokeratology-treated children using optical coherence tomography measurements

      Correlation of corneal pigmented arc with wide epithelial thickness map in orthokeratology-treated children using optical coherence tomography measurements
      Purpose To determine the intensity of corneal pigmented arc in orthokeratology (ortho-k)-treated children and its correlation with wide epithelial thickness map (ETM) obtained through anterior segment optical coherent tomography (AS-OCT). Methods This retrospective case series reviews medical records of children who received ortho-k treatment for myopia control. Intensity of ortho-k-associated pigmented arc after wearing ortho-k lens more than 12 months and its correlation with each sector/zone of wide ...
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    6. Quantification of structural and microvascular changes for diagnosing early-stage oral cancer

      Quantification of structural and microvascular changes for diagnosing early-stage oral cancer
      Changes in mucosal microvascular networks, called intraepithelial papillary capillary loops (IPCL), are an important key factor for diagnosing early-stage oral cancer in vivo. Nevertheless, there are a lack of tools to quantify these changes objectively. This is the first study to quantify the IPCL changes in vivo to differentiate benign or malignant oral lesions by the optical coherence tomography (OCT) technique. K14-EGFP-miR-211-GFP transgenic mice were inducted by 4-Nitroquinoline-1-oxide to produce ...
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    7. Diagnostic Utility of Neuroretinal Rim Thickness, Measured in Clock-Hour Sectors with HD Optical Coherence Tomography, in Preperimetric Glaucoma

      Diagnostic Utility of Neuroretinal Rim Thickness, Measured in Clock-Hour Sectors with HD Optical Coherence Tomography, in Preperimetric Glaucoma
      Background: We evaluated the usefulness of neuroretinal rim (NRR) thicknesses, measured in clock-hour sectors with Cirrus HD- optical coherence tomography (OCT), for diagnosing preperimetric glaucoma (PPG). Methods: This prospective study included 39 eyes of 39 patients with PPG and 39 eyes of 39 controls that were matched to patients for age and refractive error. We measured the circumpapillary retinal nerve fiber layer (cpRNFL) thickness, macular ganglion cellinner plexiform layer (GCIPL ...
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    8. Glaucoma assessment in high myopic eyes using optical coherence tomography with long axial length normative database

      Glaucoma assessment in high myopic eyes using optical coherence tomography with long axial length normative database
      Background: We investigated the performance of glaucoma assessment using RS-3000 spectral domain optical coherence tomography (SD-OCT) with a long axial length normative database (LAND) versus Cirrus HD-OCT in eyes with high myopia . Methods: This is a prospective case-control study. Eyes with axial length 26 mm were enrolled, including 40 control eyes and 41 eyes with primary open angle glaucoma . Each participant received OCT imaging with both devices at the same ...
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    9. OCT-Based Periodontal Inspection Framework

      OCT-Based Periodontal Inspection Framework
      Periodontal diagnosis requires discovery of the relations among teeth, gingiva (i.e., gums), and alveolar bones, but alveolar bones are inside gingiva and not visible for inspection. Traditional probe examination causes pain, and X-ray based examination is not suited for frequent inspection. This work develops an automatic non-invasive periodontal inspection framework based on gum penetrative Optical Coherence Tomography (OCT), which can be frequently applied without high radiation. We sum up ...
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    10. Optical tomography digital impression imaging system and method for use thereof

      Optical tomography digital impression imaging system and method for use thereof
      Provided are an optical tomography digital-impression imaging system and a method for use thereof, said system including: an optical coherence tomography scanner, used for obtaining tomographic slice thicknesses of a plurality of tissue areas of each optical tomography digital image; an information analysis and processing component electrically connected to the optical coherence tomography scanner. The information analysis and processing component has a refractive index compensation and optical path correction functions ...
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    11. OCT-Based Tooth Scan and Reconstruction

      OCT-Based Tooth Scan and Reconstruction
      Digital dental reconstruction can be a more efficient and effective mechanism for artificial crown construction and period inspection. However, optical methods cannot reconstruct those portions under gums, and X-ray-based methods have high radiation to limit their applied frequency. Optical coherence tomography (OCT) can harmlessly penetrate gums using low-coherence infrared rays, and thus, this work designs an OCT-based framework for dental reconstruction using optical rectification, fast Fourier transform, volumetric boundary detection ...
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    12. Imaging analysis with optical coherence tomography angiography after primary repair of macula-off rhegmatogenous retinal detachment

      Imaging analysis with optical coherence tomography angiography after primary repair of macula-off rhegmatogenous retinal detachment
      Purpose To evaluate changes in the microcirculation of various retinal layers and choroid following successful repair of macula-off rhegmatogenous retinal detachment (RRD) using optical coherence tomography angiography (OCTA). Methods Twenty-eight patients (28 eyes) who underwent successful repair of macula-off RRD were prospectively investigated. Differences in OCTA characteristics between retinal detachment (RD) and fellow eyes were compared. Quantitative measurements of the retinal capillary and choriocapillary associated with the preoperative and intraoperative ...
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    13. Supercontinuum source-based multi-contrast optical coherence tomography for rat retina imaging

      Supercontinuum source-based multi-contrast optical coherence tomography for rat retina imaging
      This study proposed an ultrahigh-resolution multi-contrast optical coherence tomography system integrated with fundus photography for in vivo retinal imaging of rodents. A supercontinuum light source was used in the system, providing an axial resolution of less than 3 m within 1.8 mm (in the tissue). Three types of tissue contrast based on backscattered intensity, phase retardation, and microvasculature at a capillary level can be simultaneously obtained using the proposed ...
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    14. Intelligent epidural needle placement using fiber-probe optical coherence tomography in a piglet model

      Intelligent epidural needle placement using fiber-probe optical coherence tomography in a piglet model
      Incorrect needle placement during an epidural block causes medical complications such as dural puncture or spinal cord injury. We propose a system combining an optical coherence tomography imaging probe with an automatic identification algorithm to objectively identify the epidural needle-tip position and thus reduce complications during epidural needle insertion. Eight quantitative features were extracted from each two-dimensional optical coherence tomography image during insertion of the needle tip from the skin ...
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    15. Review: Optical Scanning Probe for Optical Coherence Tomography

      Review: Optical Scanning Probe for Optical Coherence Tomography
      Optical coherence tomography (OCT) has become an important medical imaging modality. However, low penetration depth limits its application. Therefore, the optical scanning probe plays an important role in OCT systems for clinical applications. This article reviews OCT methodology and the mechanisms of an optical scanning probe. Recent developments of OCT probe and related clinical applications are summerized. Various OCT probe techniques (e.g., side imaging and forward imaging) have been ...
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    16. 1-15 of 39 1 2 3 »
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  2. About National Yang-Ming University

    National Yang-Ming University

    National Yang Ming University. It is known for its medical studies. The university was founded in 1975 as The National Yang-Ming Medical College to cultivate first-class medical professionals and biomedical scientists. In 1994 it was granted university status by the Ministry of Education and became the first university in Taiwan dedicated to biomedical education and research. Along with its original mission, the University now is devoted to excelling in biomedical research, and to promoting intercollegiate and international collaboration. In the 30 years since its founding, Yang-Ming has enjoyed a robust growth. By the end of the 2005 academic year, Yang-Ming became a medium-sized university with 5 schools - Medicine, Dentistry, Medical Technology and Biomedical Engineering, Life Sciences and Nursing, and a Center for General Education. Additionally, the Veterans General Hospitals, three leading medical centers with a total of more than 5,500 beds and more than 1,600 physicians , serve as the teaching hospitals for medical and paramedical students. Yang-Ming also established 15 research centers with a wide spectrum of emphases including Genomic Medicine, Brain Research, Cognitive Neuroscience, Immunology, Cellular and Molecular Biology, Biomedical Engineering, Medical Imaging, Biophoptonics, Bioinformatics, Health Informatics, AIDS, Community Medicine, and Community Nursing. The University currently has 7 departments and 28 graduate institutes with 1853 undergraduate students, 1736 graduate students, 296 full-time faculty members, and 1066 adjunct faculty members.