1. National University of Singapore

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    1. Mentioned In 176 Articles

    2. Utility of Bleb Imaging With Anterior Segment Optical Coherence Tomography in Clinical Decision-making After Trabeculectomy

      Aim: To determine if imaging of blebs with anterior segment optical coherence tomography (ASOCT) affects clinical decision-making with regard to laser suture lysis (LSL) after trabeculectomy. Method: In this prospective observational case series, we included patients with poorly controlled intraocular pressure (IOP) after standardized trabeculectomy from May to November 2006. One observer assessed IOP, anterior chamber depth and bleb formation, and recorded a decision of whether or not to undertake ...
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    3. Dark Room Provocative Test and Extent of Angle Closure: An Anterior Segment OCT Study

      Purpose: To clarify the risk parameters measured by anterior segment optical coherence tomography (AS-OCT) for elevated intraocular pressures (IOP) provoked by the darkroom test and to provide recommendations for its clinical usage.Methods: Subjects aged 40 years and whose peripheral anterior chambers were =8 mm Hg after the test. Statistical analyses included: (1) the difference in parameters between positive and negative eyes; (2) the association between posttest IOP and the ...
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    4. Macular and Nerve Fiber Layer Thickness in Amblyopia: The Sydney Childhood Eye Study

      Purpose: To examine macular and peripapillary retinal nerve fiber layer (RNFL) thickness in amblyopia.Design: Population-based cross-sectional study.Participants: Of 4118 children examined in the Sydney Childhood Eye Study (incorporating the Sydney Myopia Study) from 34 randomly selected primary schools and 21 secondary schools from 2003 to 2005, 3529 (85.7%) were included in this analysis. The median age of the 2 samples was 6 years (n = 1395) and 12 ...
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    5. Comparison of Visante and slit-lamp anterior segment optical coherence tomography in imaging the anterior chamber angle

      Aims To compare the diagnostic performance of two anterior segment optical coherence tomography (AS-OCT) devices in assessing the anterior chamber angle (ACA). Methods Visante-OCT and slit-lamp-OCT (SL-OCT) were performed on 101 patients by a single operator. The AS-OCT images were processed by customised 'dewarping' software and assessed by two glaucoma specialists masked to clinical findings. A closed ACA was defined by the presence of contact between the iris and angle ...
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    6. Optical scanning using vibratory diffraction gratings

      An optical scanning apparatus includes an in-plane vibratory mass platform having at least one diffraction grating formed thereon as the scanning element, at least one flexure structure that connects the mass platform to at least one fixed support, and at least one driving actuator that drives the mass platform into an in-plane vibratory motion which can be rotational and/or translational. The apparatus may also be formed by a mass ...
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    7. Relationship of Retinal Vascular Caliber with Optic Disc and Macular Structure

      Purpose To examine the relationships of retinal vascular caliber with optic disc, macular, and retinal nerve fiber layer (RNFL) characteristics as measured with optical coherence tomography (OCT). Design Observational cross-sectional study. Methods This study included a subset of healthy children enrolled in the Singapore Cohort Study of the Risk Factors of Myopia (SCORM). Optic disc, macular, and RNFL morphology were measured with Stratus OCT 3. Digital retinal photography was performed ...
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    8. Imaging of the anterior segment in glaucoma

      Although constituting only about a quarter of all glaucoma, angle closure glaucoma causes a disproportionate amount of visual morbidity and is predicted to be responsible for almost half of bilateral blindness by 2020. Early detection and treatment of angle closure significantly improves visual prognosis. Identification of eyes at risk of angle closure currently relies on opportunistic case detection, often by gonioscopy. However, gonioscopy is a highly subjective technique and often ...
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    9. Comparison of Slitlamp Optical Coherence Tomography and Scanning Peripheral Anterior Chamber Depth Analyzer to Evaluate Angle Closure in Asian Eyes

      Objective To evaluate the effectiveness of slitlamp optical coherence tomography (SL-OCT) and Scanning Peripheral Anterior Chamber depth analyzer (SPAC) in detecting angle closure, using gonioscopy as the reference standard. Methods A total of 153 subjects underwent gonioscopy, SL-OCT, and SPAC. The anterior chamber angle (ACA) was classified as closed on gonioscopy if the posterior trabecular meshwork could not be seen; with SL-OCT, closure was determined by contact between the iris ...
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    10. High-definition imaging of trabeculectomy blebs using spectral domain optical coherence tomography adapted for the anterior segment

      Background: The aim of this work was to image trabeculectomy blebs using spectral domain optical coherence tomography (SDOCT).Methods: In this prospective cross-sectional study, patients who had undergone trabeculectomy with at least 3 months of follow up were included. Blebs were imaged using an adapted SDOCT system (Cirrus HD-OCT, Carl Zeiss Meditec Inc., Dublin, CA, USA) and time domain anterior segment optical coherence tomography (ASOCT) (Visante OCT, Carl Zeiss Meditec ...
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    11. High-Definition Optical Coherence Tomography Imaging of the Iridocorneal Angle of the Eye

      Objective To assess the ability of high-definition optical coherence tomography (HD-OCT) to image the anterior chamber angle. Methods Forty-five consecutive subjects with phakic eyes underwent gonioscopy and anterior chamber angle imaging with HD-OCT adapted with a 60-diopter aspheric lens mounted over the imaging aperture. The patients' fixation was directed to the side using an external fixation light, and scans were taken of the temporal and nasal quadrants. The visibility of ...
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    12. Variation of Angle Parameters in Asians: An Anterior Segment Optical Coherence Tomography Study in a Population of Singapore Malays

      ...zhou, China ^6 Singapore Eye Research Institute, Singapore, Sierra Leone ^7 Community, Occup. & Family Med., National University of Singapore, Singapore, Singapore ^8 Singapore National Eye Centre, 11 Third Hospital Ave...
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    13. Comparison between confocal scanning laser tomography, scanning laser polarimetry and optical coherence tomography on the ability to detect localised retinal nerve fibre layer defects in glaucoma patients

      ...ova Scotia, Canada ^2 Ophthalmology Research Unit, Maisonneuve-Rosemont Hospital, Montreal, Quebec, Canada ^3 National University Hospital, Singapore Correspondence to: Dr M T Nicolela, Eye Care Centre, 1278 Tower Road, ...
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    14. Use of Anterior Segment Optical Coherence Tomography to Assess Secondary Glaucoma After Penetrating Keratoplasty.

      Purpose: To describe the use of anterior segment optical coherence tomography (AS-OCT) in the evaluation of a patient with raised intraocular pressures after penetrating keratoplasty. Methods: A 52-year-old Indian male with bilateral keratoconus underwent multiple penetrating keratoplasties because of repeated episodes of endothelial rejection and graft failure. He also had secondary glaucoma bilaterally for which he underwent bilateral posterior implantation of glaucoma drainage device. During the early postoperative period after ...
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    15. Screening for Narrow Angles in the Singapore Population: Evaluation of New Noncontact Screening Methods

      Purpose: To assess the screening effectiveness of 3 new noncontact devices, the scanning peripheral anterior chamber depth analyzer (SPAC) (Takagi, Nagano, Japan), which measures peripheral anterior chamber depth (ACD); IOLMaster (Carl Zeiss Meditec, Jena, Germany), which measures central ACD; and Visante anterior segment optical coherence tomography (AS-OCT) (Visante, Carl Zeiss Meditec, Dublin, CA), which images the angles, and to compare these instruments with gonioscopy in identifying people with narrow angles ...
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    16. 151-165 of 176 « 1 2 ... 8 9 10 11 12 »
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  2. About National University of Singapore

    National University of Singapore

    National University of Singapore (NUS) is Singapore's oldest university. It is the largest university in the country in terms of student enrollment and curriculum offered. National University Health System (NUHS) was incorporated in January 2008, to bring the National University Hospital (NUH), and the National University of Singapore's (NUS) Yong Loo Lin School of Medicine and the Faculty of Dentistry under a common governance structure and develop academic medicine in Singapore. NUH is on the campus of NUS.