1. National University of Singapore

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    1. Mentioned In 127 Articles

    2. Plateau Iris Distribution Across Anterior Segment Optical Coherence Tomography Defined Subgroups of Subjects With Primary Angle Closure Glaucoma

      Explore IOVS Journal Ophthalmology
      Plateau Iris Distribution Across Anterior Segment Optical Coherence Tomography Defined Subgroups of Subjects With Primary Angle Closure Glaucoma
      Purpose : We previously identified three distinct subgroups of patients with primary angle closure glaucoma (PACG) based on anterior segment optical coherence tomography (ASOCT) imaging. Group 1 was characterized by a large iris area with deepest anterior chambers, group 2 by a large lens vault (LV) and shallow anterior chamber depth (ACD), and group 3 displayed intermediate values across iris area, LV, and ACD. The purpose of the present study was ...
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      Mentions: Singapore Eye Research Institute National University of Singapore Tin Aung

    3. Comparison of anterior segment optical coherence tomography angiography systems for corneal vascularisation

      Explore BJO Online Ophthalmology
      Comparison of anterior segment optical coherence tomography angiography systems for corneal vascularisation
      Aim To newly describe a spectral-domain (SD) optical coherence tomography angiography (OCTA) for the cornea and directly compare two OCTA system scans of the same eyes with corneal vascularisation. Methods Cross-sectional, observational, comparative case series. We performed sequential OCTA scans (10 eyes of 10 subjects with corneal vascularisation,4 scans each eye) repeated using split-spectrum amplitude decorrelation algorithm angiography system (SSADA, AngioVue; Optovue Inc, USA) and SD OCTA (Angioscan; Nidek ...
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      Mentions: Optovue Nidek Medical University of Vienna

    4. Identification of imaging features that determine quality and repeatability of retinal capillary plexus density measurements in OCT angiography

      Explore BJO Online Ophthalmology
      Identification of imaging features that determine quality and repeatability of retinal capillary plexus density measurements in OCT angiography
      Purpose Optical coherence tomography angiography (OCT-A) potentially allows for rapid and non-invasive quantification of retinal capillary plexus density in various disease states. This study aims to identify the key features that influenced the repeatability of OCT-A measurements. Methods We obtained OCT-A images on two separate visits in 44 healthy eyes from 44 subjects, each imaged with using the Topcon DRI OCT Triton imaging system. The parafoveal vessel density within a ...
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      Mentions: Topcon Medical Systems Singapore Eye Research Institute National University of Singapore

    5. Segmentation and Quantification for Angle-Closure Glaucoma Assessment in Anterior Segment OCT

      Explore IEEE Xplore Ophthalmology
      Segmentation and Quantification for Angle-Closure Glaucoma Assessment in Anterior Segment OCT
      Angle-closure glaucoma is a major cause of irreversible visual impairment and can be identified by measuring the anterior chamber angle (ACA) of the eye. The ACA can be viewed clearly through anterior segment optical coherence tomography (AS-OCT), but the imaging characteristics and the shapes and locations of major ocular structures can vary significantly among different AS-OCT modalities, thus complicating image analysis. To address this problem, we propose a data-driven approach ...
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      Mentions: Singapore Eye Research Institute National University of Singapore Mani Baskaran

    6. A Deep Learning Approach to Digitally Stain Optical Coherence Tomography Images of the Optic Nerve Head

      Explore arxiv.org Ophthalmology
      A Deep Learning Approach to Digitally Stain Optical Coherence Tomography Images of the Optic Nerve Head
      Purpose. To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods. A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1 eye of each of 100 subjects (40 normal 60 glaucoma). All images were enhanced using adaptive compensation. A custom deep learning network was then designed and trained with the compensated images to digitally ...
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      Mentions: Heidelberg Engineering Singapore Eye Research Institute National University of Singapore

    7. Repeatability and Reproducibility of Retinal Neuronal and Axonal Measures on Spectral-domain Optical Coherence Tomography in Patients with Cognitive Impairment

      Explore journal.frontiersin.org Neurology , Ophthalmology
      Repeatability and Reproducibility of Retinal Neuronal and Axonal Measures on Spectral-domain Optical Coherence Tomography in Patients with Cognitive Impairment
      Background: With increasing interest in determining if measurement of retinal neuronal structure with spectral-domain optical coherence tomography (SD-OCT) is useful in accessing neurodegenerative process in cognitive decline and development of dementia, it is important to evaluate whether the SD-OCT measurements are repeatable and reproducible in patients with Alzheimers disease (AD) or mild cognitive impairment (MCI). Methods: This is a retrospective cohort study. Patients with AD or MCI with no change ...
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      Mentions: Singapore Eye Research Institute Carl Zeiss Meditec University of Melbourne

    8. Macular Ganglion Cell and Retinal Nerve Fiber Layer Thickness in Children With Refractive Errors—An Optical Coherence Tomography Study

      Explore LWW Online Ophthalmology
      Macular Ganglion Cell and Retinal Nerve Fiber Layer Thickness in Children With Refractive Errors—An Optical Coherence Tomography Study
      Purpose: To study the distribution of macular ganglion cell-inner plexiform layer (GC-IPL) thickness and peripapillary retinal nerve fiber layer (RNFL) thickness in children with refractive errors. Materials and Methods: Two hundred forty-three healthy eyes from 139 children with refractive error ranging from 10.00 to +5.00 D were recruited from the National University Hospital Eye Surgery outpatient clinic. After a comprehensive ocular examination, refraction, and axial length (AL) measurement ...
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      Mentions: Carl Zeiss Meditec National University of Singapore

    9. Feature Of The Week 05/28/2017: In Vivo 3-Dimensional Strain Mapping Confirms Large Optic Nerve Head Deformations Following Horizontal Eye Movements

      Explore Optical Coherence Tomography News Ophthalmology
      Feature Of The Week 05/28/2017: In Vivo 3-Dimensional Strain Mapping Confirms Large Optic Nerve Head Deformations Following Horizontal Eye Movements
      ...ic neuropathies. For more information see recent Article . Courtesy Xiaofei Wang and Michal J. A. Girard from National University of Singapore . Glaucoma is characterized by an irreversible damage of retinal ganglion cel...
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      Mentions: Duke University University College London National University of Singapore

    10. A Digital Staining Algorithm for Optical Coherence Tomography Images of the Optic Nerve Head

      Explore TVST Journal Ophthalmology
      A Digital Staining Algorithm for Optical Coherence Tomography Images of the Optic Nerve Head
      Purpose : To digitally stain spectral-domain optical coherence tomography (OCT) images of the optic nerve head (ONH), and highlight either connective or neural tissues. Methods : OCT volumes of the ONH were acquired from one eye of 10 healthy subjects. We processed all volumes with adaptive compensation to remove shadows and enhance deep tissue visibility. For each ONH, we identified the four most dissimilar pixel-intensity histograms, each of which was assumed to ...
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      Mentions: Singapore Eye Research Institute National University of Singapore Tin Aung

    11. Investigation of the variability of anterior chamber scan protocol with Cirrus high definition optical coherence tomography

      Explore Wiley Online Library Ophthalmology
      Investigation of the variability of anterior chamber scan protocol with Cirrus high definition optical coherence tomography
      Importance The evaluation of anterior chamber scan (ACS) of Cirrus optical coherence tomography (OCT) for routine clinical use Background To assess the variability of anterior chamber angle (ACA) measurements using the ACS Design Cross-sectional observational study Participants Forty subjects aged 40-80 years Methods One randomly selected eye from 40 subjects was imaged with Cirrus OCT (model 5000, Carl Zeiss Meditec, Dublin, CA) by two different operators (expert vs non-expert) with ...
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      Mentions: National Institutes of Health Singapore Eye Research Institute Carl Zeiss Meditec

    12. Evaluation of the Anterior Segment Angle-to-Angle Scan of Cirrus High-Definition Optical Coherence Tomography and Comparison With Gonioscopy and With the Visante OCT

      Explore IOVS Journal Ophthalmology
      Evaluation of the Anterior Segment Angle-to-Angle Scan of Cirrus High-Definition Optical Coherence Tomography and Comparison With Gonioscopy and With the Visante OCT
      Purpose : To evaluate the diagnostic performance of the anterior segment angle-to-angle scan of the Cirrus high-definition optical coherence tomography (HD-OCT) in detecting eyes with closed angles. Methods : All subjects underwent dark-room gonioscopy by an ophthalmologist. A technician performed anterior segment imaging with Cirrus ( n = 202) and Visante OCT ( n = 85) under dark-room conditions. All eyes were categorized by two masked graders as per number of closed quadrants. Each quadrant of ...
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      Mentions: Singapore Eye Research Institute National University of Singapore Mani Baskaran

    13. Artificial Intelligence With Deep Learning Technology Looks Into Diabetic Retinopathy Screening

      Explore The JAMA Network Ophthalmology
      Artificial Intelligence With Deep Learning Technology Looks Into Diabetic Retinopathy Screening
      D iabetic retinopathy is a leading cause of vision loss in the United States and globally, particularly among working-aged individuals. Diabetic retinopathy meets all the criteria for screening: first, the condition (diabetic retinopathy) is an important public health care problem; second, the epidemiology and natural history of the condition, including development from asymptomatic latent to severe disease, are adequately understood; third, the screening test (retinal photography) is simple, safe, validated ...
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      Mentions: Johns Hopkins University Singapore Eye Research Institute National University of Singapore

    14. A method to study the hemodynamics of chicken embryo's aortic arches using optical coherence tomography

      Explore Wiley Online Library Developmental Biology
      A method to study the hemodynamics of chicken embryo's aortic arches using optical coherence tomography
      Congenital cardiovascular defects are the leading cause of birth defect related death. It has been hypothesized that fluid mechanical forces of embryonic blood flow affect cardiovascular development and play a role in congenital malformations. Studies in small animal embryos can improve our understanding of congenital malformations and can lead to better treatment. We present a feasibility study in which high-resolution optical coherence tomography (OCT) and computational fluid dynamics (CFD) are ...
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      Mentions: National University of Singapore

    15. In Vivo 3-Dimensional Strain Mapping Confirms Large Optic Nerve Head Deformations Following Horizontal Eye Movements

      Explore IOVS Journal Ophthalmology
      In Vivo 3-Dimensional Strain Mapping Confirms Large Optic Nerve Head Deformations Following Horizontal Eye Movements
      Purpose : To measure lamina cribrosa (LC) strains (deformations) following abduction and adduction in healthy subjects and to compare them with those resulting from a relatively high acute intraocular pressure (IOP) elevation. Methods : A total of 16 eyes from 8 healthy subjects were included. Among the 16 eyes, 11 had peripapillary atrophy (PPA). For each subject, both optic nerve heads (ONHs) were imaged using optical coherence tomography (OCT) at baseline (twice ...
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      Mentions: National University of Singapore Mani Baskaran Tin Aung

    16. Enhancement of Corneal Visibility in Optical Coherence Tomography Images with Corneal Opacification

      Explore TVST Journal Ophthalmology
      Enhancement of Corneal Visibility in Optical Coherence Tomography Images with Corneal Opacification
      Purpose : To establish and to rank the performance of a corneal adaptive compensation (CAC) algorithm in enhancing corneal images with scars acquired from three commercially available anterior segment optical coherence tomography (ASOCT) devices. Methods : Horizontal B-scans of the cornea were acquired from 10 patients using three ASOCT devices (Spectralis, RTVue, and Cirrus). We compared ASOCT image quality (with and without CAC) by computing the intralayer contrast (a measure of shadow ...
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      Mentions: Singapore Eye Research Institute National University of Singapore Jodhbir S. Mehta
    17. 1-15 of 127 1 2 3 4 5 6 7 8 9 »
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  4. About National University of Singapore

    National University of Singapore

    National University of Singapore (NUS) is Singapore's oldest university. It is the largest university in the country in terms of student enrollment and curriculum offered. National University Health System (NUHS) was incorporated in January 2008, to bring the National University Hospital (NUH), and the National University of Singapore's (NUS) Yong Loo Lin School of Medicine and the Faculty of Dentistry under a common governance structure and develop academic medicine in Singapore. NUH is on the campus of NUS.

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    3. Diagnostic Performance of Anterior Chamber Angle Measurements for Detecting Eyes With Narrow Angles: An Anterior Segment OCT Study: An Anterior Segment OCT Study
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