Articles that mention National University of Singapore -Optical Coherence Tomography News

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1. Mentioned In 134 Articles
2. Artificial intelligence and deep learning in ophthalmology
  
  Explore BJO Online Oct 25 2018 Ophthalmology
  
  Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global interest in recent years. DL has been widely adopted in image recognition, speech recognition and natural language processing, but is only beginning to impact on healthcare. In ophthalmology, DL has been applied to fundus photographs, optical coherence tomography and visual fields, achieving robust classification performance in the detection of diabetic retinopathy and retinopathy of prematurity, the glaucoma-like disc ...
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  Mentions: University College London Medical University of Vienna Oregon Health & Science University
3. Comparison Of Optical Coherence Tomography Angiographic Changes After Anti–Vascular Endothelial Growth Factor Therapy Alone Or In Combination With Photodynamic Therapy In Polypoidal Choroidal Vasculopathy
  
  Explore LWW Online Aug 22 2018 Ophthalmology
  
  Purpose: To compare changes in optical coherence tomography angiography in eyes with polypoidal choroidal vasculopathy after treatment with antivascular endothelial growth factor monotherapy or combined with photodynamic therapy . Methods: This is a longitudinal case-controlled study. The authors performed optical coherence tomography angiography at baseline and Month 3 in patients with treatment-naive polypoidal choroidal vasculopathy undergoing monotherapy (n = 10) or combination therapy (n = 13). We analyzed flow signal within the outer ...
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  Mentions: Singapore Eye Research Institute National University of Singapore Tien Yin Wong
4. Spectral Domain-Optical Coherence Tomography Measurements in Alzheimer’s Disease: A Systematic Review and Meta-analysis
  
  Explore ScienceDirect Aug 16 2018 Neurology , Ophthalmology
  
  Topic Optical coherence tomography (OCT) is a non-invasive tool to measure specific retinal layers in the eye. The relationship of retinal spectral domain-OCT (SD-OCT) measurements with Alzheimers Disease (AD) and mild cognitive impairment (MCI) remains unclear. Hence, we conducted a systematic review and meta-analysis to examine the SD-OCT measurements in AD and MCI. Clinical Relevance Current methods of diagnosing early AD are expensive and invasive. Retinal measurements of SD-OCT, which ...
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  Mentions: Singapore Eye Research Institute National University of Singapore The Chinese University of Hong Kong
5. DRUNET: a dilated-residual U-Net deep learning network to segment optic nerve head tissues in optical coherence tomography images
  
  Explore OSA | OSA Publishing Jul 1 2018 Ophthalmology
  
  Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images may be of great interest for the clinical diagnosis and management of this pathology. A deep learning algorithm (custom U-NET) was designed and trained to segment 6 ONH tissue layers by capturing both the local (tissue texture ...
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  Mentions: University College London Singapore Eye Research Institute National University of Singapore
6. Clinical Use of Optical Coherence Tomography Angiography in Diabetic Retinopathy Treatment Ready for Showtime?
  
  Explore The JAMA Network May 29 2018 Ophthalmology
  
  Diabetic macular edema (DME) and proliferative diabetic retinopathy (PDR) are the 2 advanced stages of diabetic retinopathy (DR) that are the main causes for visual loss in patients with diabetes. Both DME and PDR can be readily diagnosed with clinical examination and, increasingly, by the noninvasive use of optical coherence tomography. However, another, less commonly recognized cause of visual loss in patients with diabetes is diabetic macular ischemia (DMI) in ...
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  Mentions: Duke University Singapore Eye Research Institute National University of Singapore
7. DRUNET: A Dilated-Residual U-Net Deep Learning Network to Digitally Stain Optic Nerve Head Tissues in Optical Coherence Tomography Images
  
  Explore arxiv.org Mar 8 2018 Ophthalmology
  
  Given that the neural and connective tissues of the optic nerve head (ONH) exhibit complex morphological changes with the development and progression of glaucoma, their simultaneous isolation from optical coherence tomography (OCT) images may be of great interest for the clinical diagnosis and management of this pathology. A deep learning algorithm was designed and trained to digitally stain (i.e. highlight) 6 ONH tissue layers by capturing both the local ...
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  Mentions: University College London Singapore Eye Research Institute National University of Singapore
8. Imaging of the lamina cribrosa and its role in glaucoma: a review
  
  Explore Wiley Online Library Dec 7 2017 Ophthalmology
  
  The lamina cribrosa of the optic nerve head serves two contrasting roles; it must be porous to allow retinal ganglion cell axons to pass through, and yet at the same time, it must also provide adequate structural support to withstand the stresses and strains across it. Improvements in imaging such as optical coherence tomography image capture and image processing have allowed detailed in vivo studies of lamina cribrosa macro- and ...
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  Mentions: Singapore Eye Research Institute National University of Singapore Michaël J. A. Girard
9. Plateau Iris Distribution Across Anterior Segment Optical Coherence Tomography Defined Subgroups of Subjects With Primary Angle Closure Glaucoma
  
  Explore IOVS Journal Oct 8 2017 Ophthalmology
  
  Purpose : We previously identified three distinct subgroups of patients with primary angle closure glaucoma (PACG) based on anterior segment optical coherence tomography (ASOCT) imaging. Group 1 was characterized by a large iris area with deepest anterior chambers, group 2 by a large lens vault (LV) and shallow anterior chamber depth (ACD), and group 3 displayed intermediate values across iris area, LV, and ACD. The purpose of the present study was ...
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  Mentions: Singapore Eye Research Institute National University of Singapore Tin Aung
10. Comparison of anterior segment optical coherence tomography angiography systems for corneal vascularisation
  
  Explore BJO Online Sep 28 2017 Ophthalmology
  
  Aim To newly describe a spectral-domain (SD) optical coherence tomography angiography (OCTA) for the cornea and directly compare two OCTA system scans of the same eyes with corneal vascularisation. Methods Cross-sectional, observational, comparative case series. We performed sequential OCTA scans (10 eyes of 10 subjects with corneal vascularisation,4 scans each eye) repeated using split-spectrum amplitude decorrelation algorithm angiography system (SSADA, AngioVue; Optovue Inc, USA) and SD OCTA (Angioscan; Nidek ...
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  Mentions: Optovue Nidek Medical University of Vienna
11. Identification of imaging features that determine quality and repeatability of retinal capillary plexus density measurements in OCT angiography
  
  Explore BJO Online Sep 2 2017 Ophthalmology
  
  Purpose Optical coherence tomography angiography (OCT-A) potentially allows for rapid and non-invasive quantification of retinal capillary plexus density in various disease states. This study aims to identify the key features that influenced the repeatability of OCT-A measurements. Methods We obtained OCT-A images on two separate visits in 44 healthy eyes from 44 subjects, each imaged with using the Topcon DRI OCT Triton imaging system. The parafoveal vessel density within a ...
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  Mentions: Topcon Medical Systems Singapore Eye Research Institute National University of Singapore
12. Segmentation and Quantification for Angle-Closure Glaucoma Assessment in Anterior Segment OCT
  
  Explore IEEE Xplore Aug 31 2017 Ophthalmology
  
  Angle-closure glaucoma is a major cause of irreversible visual impairment and can be identified by measuring the anterior chamber angle (ACA) of the eye. The ACA can be viewed clearly through anterior segment optical coherence tomography (AS-OCT), but the imaging characteristics and the shapes and locations of major ocular structures can vary significantly among different AS-OCT modalities, thus complicating image analysis. To address this problem, we propose a data-driven approach ...
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  Mentions: Singapore Eye Research Institute National University of Singapore Mani Baskaran
13. A Deep Learning Approach to Digitally Stain Optical Coherence Tomography Images of the Optic Nerve Head
  
  Explore arxiv.org Aug 7 2017 Ophthalmology
  
  Purpose. To develop a deep learning approach to digitally-stain optical coherence tomography (OCT) images of the optic nerve head (ONH). Methods. A horizontal B-scan was acquired through the center of the ONH using OCT (Spectralis) for 1 eye of each of 100 subjects (40 normal 60 glaucoma). All images were enhanced using adaptive compensation. A custom deep learning network was then designed and trained with the compensated images to digitally ...
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  Mentions: Heidelberg Engineering Singapore Eye Research Institute National University of Singapore
14. Repeatability and Reproducibility of Retinal Neuronal and Axonal Measures on Spectral-domain Optical Coherence Tomography in Patients with Cognitive Impairment
  
  Explore journal.frontiersin.org Aug 7 2017 Neurology , Ophthalmology
  
  Background: With increasing interest in determining if measurement of retinal neuronal structure with spectral-domain optical coherence tomography (SD-OCT) is useful in accessing neurodegenerative process in cognitive decline and development of dementia, it is important to evaluate whether the SD-OCT measurements are repeatable and reproducible in patients with Alzheimers disease (AD) or mild cognitive impairment (MCI). Methods: This is a retrospective cohort study. Patients with AD or MCI with no change ...
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  Mentions: Singapore Eye Research Institute Carl Zeiss Meditec University of Melbourne
15. Macular Ganglion Cell and Retinal Nerve Fiber Layer Thickness in Children With Refractive Errors—An Optical Coherence Tomography Study
  
  Explore LWW Online Jun 30 2017 Ophthalmology
  
  $Macular Ganglion Cell and Retinal Nerve Fiber Layer Thickness in Children With Refractive Errors—An Optical Coherence Tomography Study$
  Purpose: To study the distribution of macular ganglion cell-inner plexiform layer (GC-IPL) thickness and peripapillary retinal nerve fiber layer (RNFL) thickness in children with refractive errors. Materials and Methods: Two hundred forty-three healthy eyes from 139 children with refractive error ranging from 10.00 to +5.00 D were recruited from the National University Hospital Eye Surgery outpatient clinic. After a comprehensive ocular examination, refraction, and axial length (AL) measurement ...
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  Mentions: Carl Zeiss Meditec National University of Singapore
16. Feature Of The Week 05/28/2017: In Vivo 3-Dimensional Strain Mapping Confirms Large Optic Nerve Head Deformations Following Horizontal Eye Movements
  
  Explore Optical Coherence Tomography News May 28 2017 Ophthalmology
  
  ...ic neuropathies. For more information see recent Article . Courtesy Xiaofei Wang and Michal J. A. Girard from National University of Singapore . Glaucoma is characterized by an irreversible damage of retinal ganglion cel...
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  Mentions: Duke University University College London National University of Singapore
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