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National University of Ireland, Galway
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Mentioned In 105 Articles
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Comparison of Diagnostic Performance of Intracoronary Optical Coherence Tomography-based and Angiography-based Fractional Flow Reserve for Evaluation of Coronary Stenosis
Aims: To evaluate the diagnostic performance of OCT-based optical flow ratio (OFR) in unselected patients and compare it with angiography-based quantitative flow ratio (QFR), using wire-based FFR as reference standard. Methods and results: All patients with OCT and FFR assessment prior to revascularization were analyzed. OFR and QFR were computed in blinded fashion and compared with FFR, all applying same cut-off value of 0.80 to define ischemia. Paired comparison ...Read Full Article -
Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization
Most of the fundamental pathological processes in living tissues exhibit changes at the nanoscale. Noninvasive, label-free detection of structural changes in biological samples pose a significant challenge to both researchers and healthcare professionals. It is highly desirable to be able to resolve these structural changes, during physiological processes, both spatially and temporally. Modern nanoscopy largely requires labeling, is limited to superficial 2D imaging, and is generally not suitable for in ...Read Full Article -
The multi-spectral signal properties of multiple reference optical coherence tomography (Thesis)
Efforts to reduce the size and costs of optical coherence tomography systems (OCT) for consumer applications, in general, focus on Fourier-domain OCT, due to its potential to be integrated on an optical chip, implementing the interferometer and the spectrometer together as a compact system. An alternative and near-term solution is multiple reference OCT. This technique utilizes a partial mirror in the reference arm to enhance the axial imaging depth of ...Read Full ArticleMentions: National University of Ireland, Galway -
Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity
ims: A novel method for computation of fractional flow reserve (FFR) from optical coherence tomography (OCT) was developed recently. This study aimed to evaluate the diagnostic accuracy of a new OCT-based FFR (OFR) computational approach, using wire-based FFR as the reference standard. Methods and results: Patients who underwent both OCT and FFR prior to intervention were analysed. The lumen of the interrogated vessel and the ostia of the side branches ...Read Full Article -
Optical coherence tomography substudy of a prospective multicentre randomised post-market trial to assess the safety and effectiveness of the Firehawk cobalt-chromium coronary stent (rapamycin target-eluting) system for the treatment of atherosclerotic le
Aims: Durable polymer drug-eluting stents (DP-DES) may contribute to persistent inflammation, delayed endothelial healing and subsequent late DES thrombosis. The aim of this optical coherence tomography (OCT) substudy was to compare healing and neointimal coverage of a novel bioabsorbable polymer sirolimus-eluting stent (Firehawk ) (BP-DES) versus the DP-DES (XIENCE) at 90 days in an all-comers patient population. Methods and results: The TARGET All Comers study is a prospective multicentre randomised post-market ...Read Full Article -
New Volumetric Analysis Method for Stent Expansion and its Correlation With Final Fractional Flow Reserve and Clinical Outcome An ILUMIEN I Substudy
Download figure Open in new tab Download powerpoint Abstract Objectives This study sought to compare conventional methodology (CM) with a newly described optical coherence tomography (OCT)-derived volumetric stent expansion analysis in terms of fractional flow reserve (FFR)-derived physiology and device-oriented composite endpoints (DoCE). Background The analysis of coronary stent expansion with intracoronary imaging has used CM that relies on the analysis of selected single cross-sections for several decades ...Read Full Article -
Feasibility of correlation mapping optical coherence tomography angiographic technique using a 200 kHz vertical-cavity surface-emitting laser source for in vivo microcirculation imaging applications
Optical coherence tomography (OCT) angiography is a well-established in vivo imaging technique to assess the overall vascular morphology of tissues and is an emerging field of research for the assessment of blood flow dynamics and functional parameters such as oxygen saturation. In this study, we present a modified scanning-based correlation mapping OCT using a 200 kHz high-speed swept-source OCT system operating at 1300 nm and demonstrate its wide field-imaging capability ...Read Full Article -
Characterization of an amplified piezoelectric actuator for multiple-reference optical coherence tomography
The characterization of an amplified piezoelectric actuator (APA) as a new axial scanning method for multiple-reference optical coherence tomography (MR-OCT) is described. MR-OCT is a compact optical imaging device based on a recirculating reference-arm-scanning optical delay using a partial mirror that can enhance the imaging depth range by more than 10 times the reference mirrors scanning amplitude. The scanning amplitude of the used APA was varied between 30 m and ...Read Full Article -
Nano-sensitive fourier-domain optical coherence tomography inspection system
An OCT imaging system (100) comprising a radiation emitter (SLD), a radiation receiver CCD), an interferometer (FC, PC, X-Scan, Y-Scan), a controller (COMP) which controls the emitter and processes received radiation data according to OCT to provide an output image. The controller (COMP) forms a spectrum of spatial frequencies along the depth direction. It calculates from the spectrum local spectra of spatial frequencies or periods along the depth direction for ...Read Full Article -
Optical Coherence Tomography Substudy of A Prospective Multicenter Randomized Post-Market Trial to Assess the Safety and Effectiveness of the Firehawk™ Rapamycin Target Eluting Cobalt Chromium Coronary Stent System for the Treatment of Atherosclerotic Les
Aims: Durable polymer drug-eluting stents (DP DES) may contribute to persistent inflammation, delayed endothelial healing and subsequent late DES thrombosis. The aim of this Optical Coherence Tomography (OCT) sub-study was to compare healing and neointimal coverage of a novel bioabsorbable polymer sirolimus-eluting stent (FIREHAWK) (BP DES) versus the DP DES (XIENCE) at 90 days in an all comers patient population. Methods and results: The TARGET All Comers study is a ...Read Full Article -
Biophotonics and Imaging Graduate Summer School (BIGSS`18) AUGUST 28 - SEPTEMBER 1, 2018 at The Burren and NUI Galway
...Biological and translational applications. Hands on training: (Saturday in NUI Galway) Photoacoustic Imaging NUI Galway and iThera Optical Coherence Tomography NUI Galway and Thorlabs Updates here: http://tomi.nuigalwa...Read Full Article -
Postdoctoral Researcher - in Imaging Software and Algorithm Development, National University of Ireland, Galway
...s designed to support their personal career development plans. Further information on research and working at NUI Galway is available on Research at NUI Galway For information on moving to Ireland please see www.euraxess...Read Full Article -
In-stent fractional flow reserve variations and related optical coherence tomography findings: the FFR–OCT co-registration study
We sought to assess in-stent variations in fractional flow reserve (FFR) in patients with previous percutaneous coronary intervention (PCI) and to associate any drop in FFR with findings by optical coherence tomography (OCT) imaging. Suboptimal post-PCI FFR values were previously associated with poor outcomes. It is not known to which extent in-stent pressure loss contributes to reduced FFR. In this single-arm observational study, 26 patients who previously underwent PCI with ...Read Full Article -
PhD Studentships Optical Coherence Tomography / Tissue Optics / Photoacoustics: National University of Ireland, Galway
...artin.leahy@nuigalway.ie . Please put reference number NUIG-PhD-TOMI 01 -1 7 in subject line of application. National University of Ireland, Galway is an equal opportunity employer Sunday Times University of The Year;...Read Full Article
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About National University of Ireland, Galway
National University of Ireland, Galway is a constituent university of the National University of Ireland. It is a tertiary-level educational institution located in Galway, Ireland. With over 16,000 students and more than 2,200 staff, NUI Galway has a distinguished reputation for teaching and research excellence in the fields of arts, social science, and celtic studies; business, public policy and law; engineering and informatics; medicine, nursing and health sciences; and science.