1. National University of Ireland, Galway

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    1. Mentioned In 116 Articles

    2. Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal

      Accessing depth-resolved high spatial frequency content from the optical coherence tomography signal
      Optical coherence tomography (OCT) is a rapidly evolving technology with a broad range of applications, including biomedical imaging and diagnosis. Conventional intensity-based OCT provides depth-resolved imaging with a typical resolution and sensitivity to structural alterations of about 510 microns. It would be desirable for functional biological imaging to detect smaller features in tissues due to the nature of pathological processes. In this article, we perform the analysis of the spatial ...
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    3. Optical Flow Ratio for Assessing Stenting Result and Physiological Significance of Residual Disease

      Optical Flow Ratio for Assessing Stenting Result and Physiological Significance of Residual Disease
      Background: Optical flow ratio (OFR) is a novel method for fast computation of fractional flow reserve (FFR) from optical coherence tomography (OCT) images. Aims: We aimed to evaluate the accuracy of OFR in predicting post-percutaneous coronary intervention (PCI) FFR and to evaluate the impact of stent expansion on within-stent OFR pressure drop (In-stent OFR). Methods: Post-PCI OFR was computed in patients with both OCT and FFR interrogation immediately after PCI ...
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    4. Multi-modality intravascular imaging for guiding coronary intervention and assessing coronary atheroma: the Novasight Hybrid IVUS-OCT system

      Multi-modality intravascular imaging for guiding coronary intervention and assessing coronary atheroma: the Novasight Hybrid IVUS-OCT system
      Intravascular imaging has evolved alongside interventional cardiology as an adjunctive tool for assessing plaque pathology and for guiding and optimising percutaneous coronary intervention (PCI) in challenging lesions. The two modalities which have dominated the field are intravascular ultrasound (IVUS), which relies on sound waves and optical coherence tomography (OCT), relying on light waves. These approaches however have limited efficacy in assessing plaque morphology and vulnerability that are essential for guiding ...
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    5. Automatic Characterisation of Human Atherosclerotic Plaque Composition from Intravascular Optical Coherence Tomography Using Artificial Intelligence

      Automatic Characterisation of Human Atherosclerotic Plaque Composition from Intravascular Optical Coherence Tomography Using Artificial Intelligence
      Background Intravascular optical coherence tomography (IVOCT) enables detailed plaque characterisation in-vivo, but visual assessment is time-consuming and subjective. Aims This study aims to develop and validate an automatic framework for IVOCT plaque characterisation using artificial intelligence (AI). Methods IVOCT pullbacks from 5 international centres were analysed in a corelab, annotating basic plaque components, inflammatory markers and other structures. A deep convolutional network with encoding-decoding architecture and pseudo-3D input was developed ...
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    6. Characterizing thrombus with multiple red blood cell compositions by optical coherence tomography attenuation coefficient

      Characterizing thrombus with multiple red blood cell compositions by optical coherence tomography attenuation coefficient
      Embolectomy is one of the emergency procedures performed to remove emboli. Assessing the composition of human blood clots is an important diagnostic factor and could provide guidance for an appropriate treatment strategy for interventional physicians. Immunostaining has been used to identity compositions of clots as a gold-standard procedure, but it is time-consuming and cannot be performed in situ. Here, we proposed that the optical attenuation coefficient of optical coherence tomography ...
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    7. Advances in IVUS/OCT and Future Clinical Perspective of Novel Hybrid Catheter System in Coronary Imaging

      Advances in IVUS/OCT and Future Clinical Perspective of Novel Hybrid Catheter System in Coronary Imaging
      Intravascular ultrasound (IVUS) and optical coherence tomography (OCT) have been developed and improved as both diagnostic and guidance tools for interventional procedures over the past three decades. IVUS has a resolution of 100 m with a high tissue penetration and capability of assessing the entire structure of a coronary artery including the external elastic membrane, whereas OCT has a higher resolution of 1020 m to assess endoluminal structures with a ...
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    8. Nanosensitive optical coherence tomography to assess wound healing within the cornea

      Nanosensitive optical coherence tomography to assess wound healing within the cornea
      Optical Coherence Tomography (OCT) is a non-invasive depth resolved optical imaging modality, that enables high resolution, cross-sectional imaging in biological tissues and materials at clinically relevant depths. Though OCT offers high resolution imaging, the best ultra-high-resolution OCT systems are limited to imaging structural changes with a resolution of one micron on a single B-scan within very limited depth. Nanosensitive OCT (nsOCT) is a recently developed technique that is capable of ...
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    9. Automatic stent reconstruction in optical coherence tomography based on a deep convolutional model

      Automatic stent reconstruction in optical coherence tomography based on a deep convolutional model
      Intravascular optical coherence tomography (IVOCT) can accurately assess stent apposition and expansion, thus enabling the optimisation of a stenting procedure to minimize the risk of device failure. This paper presents a deep convolutional based model for automatic detection and segmentation of stent struts. The input of pseudo-3D images aggregated the information from adjacent frames to refine the probability of strut detection. In addition, multi-scale shortcut connections were implemented to minimize ...
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    10. Biophotonics and Imaging Graduate Summer School to be held on August 2020 at National University of Ireland, Galway

      Biophotonics and  Imaging  Graduate  Summer  School to be held on August 2020 at National University of Ireland, Galway
      Dates: August 25th - 29th 2020 This is our eight Biophotonics and Imaging Graduate Summer School. It is an important opportunity for graduate students in 2020 to access the kind of close contact with leading professors that only this kind of environment facilitates. Tutors for BIGSS 2020 will include: Martin Booth (Oxford): Advanced Microscopy Steve Jacques (Washington): Tissue Optics Caroline Boudoux (Montreal): Endoscopy David Sampson (Surrey): OCT Sarah Bohndiek (Cambridge): Photoacoustics ...
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    11. Comparison of Diagnostic Performance of Intracoronary Optical Coherence Tomography-based and Angiography-based Fractional Flow Reserve for Evaluation of Coronary Stenosis

      Comparison of Diagnostic Performance of Intracoronary Optical Coherence Tomography-based and Angiography-based Fractional Flow Reserve for Evaluation of Coronary Stenosis
      Aims: To evaluate the diagnostic performance of OCT-based optical flow ratio (OFR) in unselected patients and compare it with angiography-based quantitative flow ratio (QFR), using wire-based FFR as reference standard. Methods and results: All patients with OCT and FFR assessment prior to revascularization were analyzed. OFR and QFR were computed in blinded fashion and compared with FFR, all applying same cut-off value of 0.80 to define ischemia. Paired comparison ...
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    12. Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization

      Spatial frequency domain correlation mapping optical coherence tomography for nanoscale structural characterization
      Most of the fundamental pathological processes in living tissues exhibit changes at the nanoscale. Noninvasive, label-free detection of structural changes in biological samples pose a significant challenge to both researchers and healthcare professionals. It is highly desirable to be able to resolve these structural changes, during physiological processes, both spatially and temporally. Modern nanoscopy largely requires labeling, is limited to superficial 2D imaging, and is generally not suitable for in ...
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    13. The multi-spectral signal properties of multiple reference optical coherence tomography (Thesis)

      The multi-spectral signal properties of multiple reference optical coherence tomography (Thesis)
      Efforts to reduce the size and costs of optical coherence tomography systems (OCT) for consumer applications, in general, focus on Fourier-domain OCT, due to its potential to be integrated on an optical chip, implementing the interferometer and the spectrometer together as a compact system. An alternative and near-term solution is multiple reference OCT. This technique utilizes a partial mirror in the reference arm to enhance the axial imaging depth of ...
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  2. About National University of Ireland, Galway

    National University of Ireland, Galway

    National University of Ireland, Galway is a constituent university of the National University of Ireland. It is a tertiary-level educational institution located in Galway, Ireland. With over 16,000 students and more than 2,200 staff, NUI Galway has a distinguished reputation for teaching and research excellence in the fields of arts, social science, and celtic studies; business, public policy and law; engineering and informatics; medicine, nursing and health sciences; and science.