1. National Taiwan University

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    1. Mentioned In 108 Articles

    2. Optical coherence tomography/angiography-guided tumor ablation with a continuous-wave laser diode

      Optical coherence tomography/angiography-guided tumor ablation with a continuous-wave laser diode
      Laser ablation can be an effective modality for treatment, but it is complicated to apply continuous-wave (CW) light sources for laser ablation because of the unpredictable photothermal damage. In this study, an integrated theranostic system combining a low-cost CW laser diode with optical coherence tomography (OCT)/angiography (OCTA) was utilized for the in vivo ablation of tumor tissues. To examine the effect of laser exposure on tissue scattering characteristics, the ...
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    3. Tandem Mach Zehnder Directional Coupler Design and Simulation on Silicon Platform for Optical Coherence Tomography Applications

      Tandem Mach Zehnder Directional Coupler Design and Simulation on Silicon Platform for Optical Coherence Tomography Applications
      We design and compare the splitting ratio wavelength flatness of directional coupler (DC), Mach-Zehnder directional coupler (MZDC), and tandem MZDC. All coupler responses are analyzed, and tandem MZDC performance is the best in the wavelength insensitivity compared with the other two. An MZDC with any coupling ratio could be utilized to match the maximum flatness in a 40-nm wavelength range. To extend a broad flatness range, the tandem MZDC is ...
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    4. Early detection of enamel demineralization by optical coherence tomography

      Early detection of enamel demineralization by optical coherence tomography
      Enamel is the outermost layer of the tooth that protects it from invasion. In general, an acidic environment accelerates tooth demineralization, leading to the formation of cavities. Scanning electron microscopy (SEM) is conventionally used as an in vitro tool for the observation of tooth morphology changes with acid attacks. Yet, SEM has intrinsic limitations for the potential application of in vivo detection in the early demineralization process. In this study ...
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    5. Ultrahigh-resolution optical coherence tomography/angiography with an economic and compact supercontinuum laser

      Ultrahigh-resolution optical coherence tomography/angiography with an economic and compact supercontinuum laser
      In this study, a Q-switch pumped supercontinuum laser (QS-SCL) is used as a light source for in vivo imaging via ultrahigh-resolution optical coherence tomography and angiography (UHR-OCT/OCTA). For this purpose, an OCT system based on a spectral-domain detection scheme is constructed, and a spectrometer with a spectral range of 635875 nm is designed. The effective full-width at half maximum of spectrum covers 150 nm, and the corresponding axial and ...
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    6. OCT-Based Tooth Scan and Reconstruction

      OCT-Based Tooth Scan and Reconstruction
      Digital dental reconstruction can be a more efficient and effective mechanism for artificial crown construction and period inspection. However, optical methods cannot reconstruct those portions under gums, and X-ray-based methods have high radiation to limit their applied frequency. Optical coherence tomography (OCT) can harmlessly penetrate gums using low-coherence infrared rays, and thus, this work designs an OCT-based framework for dental reconstruction using optical rectification, fast Fourier transform, volumetric boundary detection ...
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    7. Correlations between visual acuity and macular microvasculature quantified with optical coherence tomography angiography in diabetic macular oedema

      Correlations between visual acuity and macular microvasculature quantified with optical coherence tomography angiography in diabetic macular oedema
      Purpose To explore the impact of macular ischaemia on vision in diabetic macular oedema (DMO) by analysing the correlations between visual acuity and macular microvascular parameters using optical coherence tomography angiography (OCTA). Methods OCTA was performed in 81 eyes of 48 patients with DMO, and 33-mm 2 en face OCTA images of the superficial capillary plexus and deep capillary plexus in the central macula were retrospectively collected. Microvascular parameters including ...
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    8. Myopic traction maculopathy biomarkers on optical coherence tomography angiography—An overlooked mechanism of visual acuity correction in myopic eyes

      Myopic traction maculopathy biomarkers on optical coherence tomography angiography—An overlooked mechanism of visual acuity correction in myopic eyes
      Background/objectives Myopic traction maculopathy of the retinoschisis type is a unique entity that has been frequently overlooked in refraction correction in daily practice in myopic eyes. The objective of this study was to describe the imaging characteristics of myopic traction maculopathy (MTM) seen on optical coherence tomography angiography (OCTA) and to detect biomarkers of the associated functional changes. Subjects/methods We performed OCTA on eyes with MTM and retinoschisis ...
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    9. Biomarkers of optical coherence tomography in evaluating the treatment outcomes of neovascular age-related macular degeneration: a real-world study

      Biomarkers of optical coherence tomography in evaluating the treatment outcomes of neovascular age-related macular degeneration: a real-world study
      This study evaluated the characteristic changes in optical coherence tomography (OCT) biomarkers in neovascular age-related macular degeneration (nAMD) treated with anti-vascular endothelial growth factor drugs and their relationship with visual outcomes at 1-year follow-up in a real-world setting. We retrospectively reviewed the medical records of 126 eyes with nAMD treated with either intravitreal ranibizumab or aflibercept, including ophthalmologic examinations and spectral-domain OCT at baseline and months 3, 6, and 12 ...
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    10. Characterizing Branching Vascular Network Morphology in Polypoidal Choroidal Vasculopathy by Optical Coherence Tomography Angiography

      Characterizing Branching Vascular Network Morphology in Polypoidal Choroidal Vasculopathy by Optical Coherence Tomography Angiography
      This study analyze the morphological characteristics of branching vascular networks (BVN) in polypoidal choroidal vasculopathy (PCV) using optical coherence tomography angiography (OCTA), and correlate imaging characteristics with clinical presentations. We presented a retrospective observational case series for fifty cases of PCV confirmed by indocyanine green angiography. Macular OCTA were done by the AngioVue. The PCV cases were classified by distinct morphologic patterns of BVN by two retina specialists and clinical ...
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    11. En Face and Cross-sectional Corneal Tomograms Using Sub-micron spatial resolution Optical Coherence Tomography

      En Face and Cross-sectional Corneal Tomograms Using Sub-micron spatial resolution Optical Coherence Tomography
      Accurate diagnosis of corneal pathology and morphological identification of different corneal layers require clear delineation of corneal three-dimensional structures and en face or cross-sectional imaging of palisade of Vogt (POV), neovascularization (NV) or corneal nerves. Here we report a prototype of full-field optical coherence tomography (FF-OCT) system with isotropic sub-micron spatial resolution in the en face and cross-sectional views. It can also provide three-dimensional reconstructed images and a large field ...
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    12. Feature Of The Week 08/31/2018: Spectroscopic Characterization of Si/Mo Thin-film Stack at Extreme Ultraviolet Range

      Feature Of The Week 08/31/2018: Spectroscopic Characterization of Si/Mo Thin-film Stack at Extreme Ultraviolet Range
      ...imaging on organelles in the future. For more information see recent Article . Courtesy Sheng-Lung Huang from National Taiwan University . Using extreme ultraviolet (EUV) radiation for nanoscale imaging has recently seen...
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    13. Quantifying scattering coefficient for multiple scattering effect by combining optical coherence tomography with finite-difference time-domain simulation method

      Quantifying scattering coefficient for multiple scattering effect by combining optical coherence tomography with finite-difference time-domain simulation method
      In optical coherence tomography (OCT) systems, to precisely obtain the scattering properties of samples is an essential issue in diagnostic applications. Especially with a higher density turbid medium, the light interferes among the adjacent scatters. Combining an OCT experiment with the finite-difference time-domain simulation method, the multiple scattering effect is shown to affect the scattering properties of medium depending on the interparticle spacing. The far-field scattering phase function of scatters ...
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    14. In vivo detection of UV-induced acute skin effects using optical coherence tomography

      In vivo detection of UV-induced acute skin effects using optical coherence tomography
      Ultraviolet (UV) rays have been identified as a carcinogen with long-term irradiation and are an important risk factor for skin cancer. Here, we report the use of optical coherence tomography/optical coherence tomography angiography (OCT/OCTA) to study acute UV-induced effects on skin in vivo . To understand the relationship between the acute effects and irradiated UV power density, three groups were irradiated with different power densities in our experiments. Furthermore ...
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  2. About National Taiwan University

    National Taiwan University

    National Taiwan University main campus is set upon 1,086,167 square meters in Taipei's Daan District. In addition, the university has 6 other campuses in Taiwan, occupying a total of 345,830,000 square meters. NTU is the top ranking University by scientific paper performance in Taiwan and ranked the 102nd in the world. Currently the University consists of 11 colleges, 54 departments, 96 graduate institutes and 4 research centers and offers diplomas in over 100 fields of study. NTU was founded in 1928 by the Japanese during the Japanese colonial era and was then known as the Taihoku (Taipei) Imperial University. After World War II and Taiwan's retrocession to Chinese sovereignty, the Taiwan government resumed the admnistration of Taihoku University and reorganized and renamed it National Taiwan University on November 15, 1945.