1. Nanyang Technological University

    0 Comments Leave a Comment

    1-15 of 141 1 2 3 4 5 6 7 8 9 10 »
    1. Mentioned In 141 Articles

    2. Effect of spectral leakage on the image formation of Fourier-domain optical coherence tomography

      Effect of spectral leakage on the image formation of Fourier-domain optical coherence tomography
      We report on the investigation of spectral leakages impact on the reconstruction of Fourier-domain optical coherence tomography (FD-OCT). We discuss the shift-variant nature introduced by the spectral leakage and develop a novel spatial-domain FD-OCT image formation model. A proof-of-concept phantom experiment is conducted to validate our model. Compared with previous models, the proposed framework could better describe the image formation process, especially when the fineness of the axial structure approaches ...
      Read Full Article
    3. Comparison of two different optical coherence tomography angiography devices in detecting healthy versus glaucomatous eyes - an observational cross-sectional study

      Comparison of two different optical coherence tomography angiography devices in detecting healthy versus glaucomatous eyes - an observational cross-sectional study
      Background: To understand the differences between two different optical coherence tomography angiography (OCTA) devices in detecting glaucomatous from healthy eyes by comparing their vascular parameters, diagnostic accuracy and test-retest reliability. Methods: A cross-sectional observational study was performed on healthy and glaucoma subjects, on whom two sets of OCTA images of optic disc and macula were acquired using both AngioVue (Optovue, USA) and Swept Source (Topcon, Japan) OCTA devices during one ...
      Read Full Article
    4. Evaluation of ultrahigh-resolution optical coherence tomography for basal cell carcinoma, seborrheic keratosis, and nevus

      Evaluation of ultrahigh-resolution optical coherence tomography for basal cell carcinoma, seborrheic keratosis, and nevus
      Background: Basal cell carcinoma, seborrheic keratosis, and nevus are common skin conditions. Though most of the skin diseases can be distinguished from each other by physician's naked eyes, the diagnostic accuracy is not 100%. The accurate diagnosis and assessment of three diseases make a big difference on the clinical management. Nowadays, biopsy is still the gold standard for diagnosis even it is invasive, time-consuming, and painful. Ultrahigh-resolution optical coherence ...
      Read Full Article
    5. Anterior segment optical coherence tomography angiography for iris vasculature in pigmented eyes

      Anterior segment optical coherence tomography angiography for iris vasculature in pigmented eyes
      Purpose To compare anterior segment optical coherence tomography angiography (AS-OCTA) systems in delineating normal iris vessels and iris neovascularisation (NVI) in eyes with pigmented irides. Methods Prospective study from January 2019 to June 2019 of 10 consecutive patients with normal pigmented iris, had AS-OCTA scans with a described illumination technique, before using the same protocol in five eyes with NVI (clinical stages 13). All scans were sequentially performed using a ...
      Read Full Article
    6. Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease

      Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease
      Imaging has become indispensable in the diagnosis and management of diseases in the posterior part of the eye. In recent years, imaging techniques for the anterior segment are also gaining importance and are nowadays routinely used in clinical practice. Ocular surface disease is often synonymous with dry eye disease, but also refers to other conditions of the ocular surface, such as Meibomian gland dysfunction or keratitis and conjunctivitis with different ...
      Read Full Article
    7. Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples

      Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples
      Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in textural and geometric features of the OCT images, which are used by human expertise to interpret and triage. However, it suffers delays due to the long process of the conventional diagnostic procedure and shortage of human expertise. Here ...
      Read Full Article
    8. Methods to improve axial resolution in optical coherence tomography

      Methods to improve axial resolution in optical coherence tomography
      Methods are proposed to improve axial resolution in optical coherence tomography (OCT). In one aspect, the method comprises: obtaining a k-space interferogram of an OCT spectral image; uniformly reshaping the k-space interferogram to a quasi-stationary interferogram by extracting a source envelope; fitting a spectral estimation model to the quasi-stationary interferogram; and calculating an axial depth profile using the fitted spectral estimation model.
      Read Full Article
    9. Stable complex conjugate artifact removal in OCT using circularly polarized light as reference

      Stable complex conjugate artifact removal in OCT using circularly polarized light as reference
      In Fourier domain optical coherence tomography (FDOCT), the depth profile is mirrored about the zero delay between the sample and reference optical paths, limiting the imaging depth to half of the entire ranging space and undermining the optimal sensitivity window. We present a new method, to the best of our knowledge, to remove the complex conjugate artifact by using circularly polarized light as reference. Quadrature detection of the complex fringe ...
      Read Full Article
    10. Are choriocapillaris flow void features robust to diurnal variations? A swept-source optical coherence tomography angiography (OCTA) study

      Are choriocapillaris flow void features robust to diurnal variations? A swept-source optical coherence tomography angiography (OCTA) study
      We evaluated the impact of diurnal variation on choroidal and retinal microvasculature and structural measurements using a swept-source optical coherence tomography angiography machine (SS-OCTA; PLEX Elite 9,000, Carl Zeiss Meditec, Inc., Dublin, USA). Fourteen participants who were without ocular diseases underwent SS-OCTA imaging using 33-mm 2 macular scan pattern on two separate days at five time points. Choriocapillaris flow voids were generated to determine its density (percentage), size (m ...
      Read Full Article
    11. Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy

      Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy
      Diabetic retinopathy (DR) is a common complication of diabetes mellitus that disrupts the retinal microvasculature and is a leading cause of vision loss globally. Recently, optical coherence tomography angiography (OCTA) has been developed to image the retinal microvasculature, by generating 3-dimensional images based on the motion contrast of circulating blood cells. OCTA offers numerous benefits over traditional fluorescein angiography in visualizing the retinal vasculature in that it is non-invasive and ...
      Read Full Article
    12. Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope

      Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope
      Background/ims To compare the retinal vessel diameter measurements obtained from the swept-source optical coherence tomography angiography (OCTA; Plex Elite 9000, Carl Zeiss Meditec, USA) and adaptive optics ophthalmoscope (AOO; RTX1, Imagine Eyes, France). Methods Fifteen healthy subjects, 67% women, mean age (SD) 30.87 (6.19) years, were imaged using OCTA and AOO by a single experienced operator on the same day. Each eye was scanned using two OCTA ...
      Read Full Article
    13. Towards Indicating Human Skin State In Vivo Using Geometry-Dependent Spectroscopic Contrast Imaging

      Towards Indicating Human Skin State In Vivo Using Geometry-Dependent Spectroscopic Contrast Imaging
      Skin plays a significant role in human body function and its collagen states change during the human skin ageing process, which affects skin function. We previously reported on geometry-dependent spectroscopic contrast achieved by spectroscopic micro-optical coherence tomography ( S OCT), which discovered that transversely oriented and regularly arranged nano-cylinders selectively backscatter the long-wavelength lights and generate spectral centroid (SC) shifts towards the long wavelengths within a spectral window of 700 950 ...
      Read Full Article
    14. Real-time en-face Gabor optical coherence tomographic angiography on human skin using CUDA GPU

      Real-time en-face Gabor optical coherence tomographic angiography on human skin using CUDA GPU
      We recently proposed an optical coherence tomographic angiography (OCTA) algorithm, Gabor optical coherence tomographic angiography (GOCTA), which can extract microvascular signals from a spectral domain directly with lower computational complexity compared to other algorithms. In this manuscript, we combine a programmable swept source, an OCT complex signal detecting unit, and graphics process units (GPU) to achieve a real-time en-face GOCTA system for human skin microvascular imaging. The programmable swept source ...
      Read Full Article
    15. Automatic differentiation of nonkeratinized stratified squamous epithelia and columnar epithelia through feature structure extraction using OCT

      Automatic differentiation of nonkeratinized stratified squamous epithelia and columnar epithelia through feature structure extraction using OCT
      As a type of precancerous lesion, metaplasia is usually considered to be associated with developing cancer. In clinical practice, surveillance of metaplastic cases usually relies on excisional biopsy followed by histological processing and analysis. As it is an invasive method accompanied by other complications, non-invasive imaging methods such as optical coherence tomography (OCT) can complement the existing method by enabling large area scanning. However, because it takes time to review ...
      Read Full Article
    16. Postdoctoral Research Fellow In Ocular Imaging Program at the Singapore Eye Research Institute

      Postdoctoral Research Fellow In Ocular Imaging Program at the Singapore Eye Research Institute
      ... research programmes for eye diseases. Recently SERI has established an ocular imaging program together with Nanyang Technological University (NTU) under the directorship of Prof. Leopold Schmetterer. SERI is seeking a ...
      Read Full Article
    17. 1-15 of 141 1 2 3 4 5 6 7 8 9 10 »
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Nanyang Technological University

    Nanyang Technological University

    Nanyang Technological University (NTU is an internationally reputed research-intensive tertiary institution. Our broad-based education covers science and technology, business and the arts, entrepreneurial and leadership skills to prepare students for the global working world.