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1. Mentioned In 97 Articles
2. Intelligent Detection of Glaucoma Using Ballistic Optical Imaging
  
  Explore ResearchGate May 11 2019 Ophthalmology
  
  Immense imaging strategies have been adept in sprouting investigative supports for glaucoma discovery. Ballistic optical imaging such as optical coherence tomography have been inspected for estimating the key constraints for glaucoma estimation such as disc area, cup area, cup volume, disc and rim area, cup to disc ratio and thickness of the retinal nerve fibre layer. This paper presents a scheme for glaucoma detection by ballistic optical imaging and machine ...
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  Mentions: Stanford University Harvard University Nanyang Technological University
3. Are nuclei in stratified squamous epithelium high scattering or low scattering?
  
  Explore arxiv.org Mar 23 2019
  
  Imaging nuclei of keratinocytes in the stratified squamous epithelium has been a subject of intense research since nucleus associated cellular atypia is the key criteria for the screening and diagnosis of epithelial cancers and their precursors. However, keratinocyte nuclei have been reported to be either low scattering or high scattering, so that these inconsistent reports might have led to misinterpretations of optical images, and more importantly, hindered the establishment of ...
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  Mentions: Nanyang Technological University Linbo Liu
4. Single input state polarization-sensitive optical coherence tomography with high resolution and polarization distortion correction
  
  Explore OSA | OSA Publishing Feb 28 2019
  
  Abstract: In single input state polarization-sensitive optical coherence tomography (PS-OCT) with high resolution, the imperfections of quarter-wave plate (QWP) and the sensitivity roll-off mismatch between the two detection channels cause unpredictable polarization distortion. We present a correction method based on the Jones matrix modeling of the system. In a single input PS-OCT system working at 840 nm with an axial resolution of ~2.3 m, the method yielded better estimation ...
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  Mentions: Nanyang Technological University Linbo Liu
5. Optical coherence tomography with gapped spectrum
  
  Explore IEEE Xplore Feb 19 2019
  
  The axial resolution of optical coherence tomography (OCT) is determined by the spectral shape and bandwidth of the detected light, which are limited by the gaps in the wavelength range of illumination, transmission, and detection. In this work, we demonstrate that the axial resolution deteriorated by gaps in OCT spectra can be restored by adopting the gapped amplitude and phase estimation (GAPES) method. GAPES estimates the missing parts between separated ...
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  Mentions: Nanyang Technological University Linbo Liu
6. Nondestructive Measurement of Conformal Coating Thickness on Printed Circuit Board with Ultra-high Resolution Optical Coherence Tomography
  
  Explore IEEE Xplore Feb 5 2019 NDE/NDT
  
  Conformal coating (CC) is widely used to protect printed circuit board (PCB) from corrosion, mould growth and electrical failures. To ensure an effective protection, the thickness of the conformal coating layer needs to be well controlled. However, to date, the coating thickness is usually measured in a destructive way under microscopes. In this study, we proposed to use optical coherence tomography (OCT) to measure the CC thickness nondestructively. Specifically, to ...
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  Mentions: Nanyang Technological University University of Iowa Linbo Liu
7. Cake formation of bidisperse suspensions in dead-end microfiltration
  
  Explore ScienceDirect Feb 3 2019 NDE/NDT
  
  The evolution of the cake during dead-end microfiltration of different compositions of bidisperse feeds was investigated using network modeling and three-dimensional (3D) optical coherence tomography (OCT) imaging. The foulant particles were latex of two different sizes (namely, 3 and 5 m) and the membrane was polycarbonate track-etched with nominal diameter of 2 m. The results from the network model indicate that (i) the deposition of the smaller particles on the ...
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  Mentions: Nanyang Technological University
8. Cellular resolution corneal imaging with extended imaging range
  
  Explore OSA | OSA Publishing Jan 31 2019 Ophthalmology
  
  Current optical coherence tomography (OCT) technology, which is used for imaging the eyes anterior segment, has been established as a clinical gold standard for the diagnosis of corneal diseases. However, the cellular resolution level information that is critical for many clinical applications is still not available. The major technical challenges toward cellular resolution OCT imaging are the limited ranging depth and depth of focus (DOF). In this work, we present ...
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  Mentions: Nanyang Technological University Linbo Liu
9. Development of cellular resolution optical coherence tomography (Thesis)
  
  Explore DR-NTU HOME Jan 28 2019 Student Theses
  
  Diagnosis of most mucosal diseases including epithelial cancers relies on white-light endoscopy/visual inspection followed by random biopsy and histologic examination. These current standard-of-care tools are associated with many issues such as sampling errors, tissue destruction, and processing artifacts. In addition, it is too traumatic to take a biopsy from tissues like eyes and coronary arteries. Being high resolution, high speed, and non-invasive, optical coherence tomography (OCT) has emerged as ...
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  Mentions: Nanyang Technological University
10. Imaging in myopia: potential biomarkers, current challenges and future developments
  
  Explore BJO Online Jan 12 2019 Ophthalmology
  
  Myopia is rapidly increasing in Asia and around the world, while it is recognised that complications from high myopia may cause significant visual impairment. Thus, imaging the myopic eye is important for the diagnosis of sight-threatening complications, monitoring of disease progression and evaluation of treatments. For example, recent advances in high-resolution imaging using optical coherence tomography may delineate early myopic macula pathology, optical coherence tomography angiography may aid early choroidal ...
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  Mentions: Columbia University Medical University of Vienna Singapore Eye Research Institute
11. Quantitative analysis of choriocapillaris in non-human primates using swept-source optical coherence tomography angiography (SS-OCTA)
  
  Explore OSA | OSA Publishing Dec 26 2018 Ophthalmology
  
  The choriocapillaris is a unique vascular plexus located posterior to the retinal pigment epithelium. In recent years, there is an increasing interest in the examination of the interrelationship between the choriocapillaris and eye diseases. We used several techniques to study choroidal perfusion, including laser Doppler flowmetry, laser speckle flowgraphy, and optical coherence tomography angiography (OCTA), but with the latter no standardized algorithm for quantitative analysis has been provided. We analyzed ...
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  Mentions: Medical University of Vienna Carl Zeiss Meditec Nanyang Technological University
12. Estimation of refractive index for biological tissue using micro-optical coherence tomography
  
  Explore IEEE Xplore Dec 12 2018
  
  $Estimation of refractive index for biological tissue using micro-optical coherence tomography$
  The refractive index of biological tissue is required for investigating the tissue's optical properties. Efforts have been made to characterize refractive indices of biological tissues at a single wavelength, but it is more convenient to know the Cauchy's coefficients, which provide refractive index over a wide range of wavelengths. We demonstrate a method to noninvasively provide the Cauchy's dispersion coefficients of biological tissues using micro-optical coherence tomography ...
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  Mentions: Nanyang Technological University Linbo Liu
13. Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples
  
  Explore arxiv.org Dec 11 2018
  
  Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in textural and geometric features of the OCT images which are used by human expertise to interpret and triage. However, it suffers delays due to long process of conventional diagnostic procedure and shortage of human expertise. Here, a custom ...
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  Mentions: Dalip Singh Mehta Indian Institute of Technology at Delhi Nanyang Technological University
14. Imaging cellular structures of atherosclerotic coronary arteries using circumferentially scanning micro-optical coherence tomography fiber probe ex vivo
  
  Explore IEEE Xplore Nov 6 2018 Cardiology
  
  Development and progression of coronary atherosclerotic lesions is mediated by a number of cellular components, which are not readily visualized using the current clinical investigation tools. Visualizing these cellular components in situ and in vivo may allow early detection of the vulnerable plaques, with implications for coronary artery disease (CAD) therapy and for the prevention of acute myocardial infarction (AMI). In this study, we have developed a fiber-optic micro-optical coherence ...
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  Mentions: Nanyang Technological University Linbo Liu Soochow University
15. Artificial intelligence and deep learning in ophthalmology
  
  Explore BJO Online Oct 25 2018 Ophthalmology
  
  Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global interest in recent years. DL has been widely adopted in image recognition, speech recognition and natural language processing, but is only beginning to impact on healthcare. In ophthalmology, DL has been applied to fundus photographs, optical coherence tomography and visual fields, achieving robust classification performance in the detection of diabetic retinopathy and retinopathy of prematurity, the glaucoma-like disc ...
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  Mentions: University College London Medical University of Vienna Oregon Health & Science University
16. Comparison of Optical Coherence Tomography Angiography to Indocyanine Green Angiography and Slit Lamp Photography for Corneal Vascularization in an Animal Model
  
  Explore Nature Publishing Group Aug 4 2018 Ophthalmology
  
  Corneal neovascularization (CoNV) could be treated by novel anti-angiogenic therapies, though reliable and objective imaging tools to evaluate corneal vasculature and treatment efficacy is still lacking. Optical coherence tomography angiography (OCTA) currently designed as a retinal vascular imaging system has been recently adapted for anterior-segment and showed good potential for successful imaging of CoNV. However, further development requires an animal model where parameters can be studied more carefully with histological ...
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  Mentions: Medical University of Vienna Nanyang Technological University Jodhbir S. Mehta
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