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    1. Mentioned In 138 Articles

    2. Anterior segment optical coherence tomography angiography for iris vasculature in pigmented eyes

      Explore BJO Online Ophthalmology
      Anterior segment optical coherence tomography angiography for iris vasculature in pigmented eyes
      Purpose To compare anterior segment optical coherence tomography angiography (AS-OCTA) systems in delineating normal iris vessels and iris neovascularisation (NVI) in eyes with pigmented irides. Methods Prospective study from January 2019 to June 2019 of 10 consecutive patients with normal pigmented iris, had AS-OCTA scans with a described illumination technique, before using the same protocol in five eyes with NVI (clinical stages 13). All scans were sequentially performed using a ...
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      Mentions: Medical University of Vienna Singapore Eye Research Institute Nanyang Technological University

    3. Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease

      Explore MDPI Open Access Journals Platform Ophthalmology
      Novel Approaches for Imaging-Based Diagnosis of Ocular Surface Disease
      Imaging has become indispensable in the diagnosis and management of diseases in the posterior part of the eye. In recent years, imaging techniques for the anterior segment are also gaining importance and are nowadays routinely used in clinical practice. Ocular surface disease is often synonymous with dry eye disease, but also refers to other conditions of the ocular surface, such as Meibomian gland dysfunction or keratitis and conjunctivitis with different ...
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      Mentions: Medical University of Vienna Singapore Eye Research Institute Nanyang Technological University

    4. Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples

      Explore OSA | OSA Publishing
      Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples
      Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in textural and geometric features of the OCT images, which are used by human expertise to interpret and triage. However, it suffers delays due to the long process of the conventional diagnostic procedure and shortage of human expertise. Here ...
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      Mentions: Dalip Singh Mehta Indian Institute of Technology at Delhi Nanyang Technological University

    5. Methods to improve axial resolution in optical coherence tomography

      Explore uspto.gov Patents
      Methods to improve axial resolution in optical coherence tomography
      Methods are proposed to improve axial resolution in optical coherence tomography (OCT). In one aspect, the method comprises: obtaining a k-space interferogram of an OCT spectral image; uniformly reshaping the k-space interferogram to a quasi-stationary interferogram by extracting a source envelope; fitting a spectral estimation model to the quasi-stationary interferogram; and calculating an axial depth profile using the fitted spectral estimation model.
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      Mentions: Nanyang Technological University Linbo Liu

    6. Stable complex conjugate artifact removal in OCT using circularly polarized light as reference

      Explore OSA | OSA Publishing
      Stable complex conjugate artifact removal in OCT using circularly polarized light as reference
      In Fourier domain optical coherence tomography (FDOCT), the depth profile is mirrored about the zero delay between the sample and reference optical paths, limiting the imaging depth to half of the entire ranging space and undermining the optimal sensitivity window. We present a new method, to the best of our knowledge, to remove the complex conjugate artifact by using circularly polarized light as reference. Quadrature detection of the complex fringe ...
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      Mentions: Medical University of Vienna Singapore Eye Research Institute Nanyang Technological University

    7. Are choriocapillaris flow void features robust to diurnal variations? A swept-source optical coherence tomography angiography (OCTA) study

      Explore Nature Publishing Group Ophthalmology
      Are choriocapillaris flow void features robust to diurnal variations? A swept-source optical coherence tomography angiography (OCTA) study
      We evaluated the impact of diurnal variation on choroidal and retinal microvasculature and structural measurements using a swept-source optical coherence tomography angiography machine (SS-OCTA; PLEX Elite 9,000, Carl Zeiss Meditec, Inc., Dublin, USA). Fourteen participants who were without ocular diseases underwent SS-OCTA imaging using 33-mm 2 macular scan pattern on two separate days at five time points. Choriocapillaris flow voids were generated to determine its density (percentage), size (m ...
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      Mentions: Medical University of Vienna Singapore Eye Research Institute Carl Zeiss Meditec

    8. Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy

      Explore MDPI Open Access Journals Platform
      Optical Coherence Tomography Angiography in Diabetes and Diabetic Retinopathy
      Diabetic retinopathy (DR) is a common complication of diabetes mellitus that disrupts the retinal microvasculature and is a leading cause of vision loss globally. Recently, optical coherence tomography angiography (OCTA) has been developed to image the retinal microvasculature, by generating 3-dimensional images based on the motion contrast of circulating blood cells. OCTA offers numerous benefits over traditional fluorescein angiography in visualizing the retinal vasculature in that it is non-invasive and ...
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      Mentions: Medical University of Vienna Singapore Eye Research Institute Nanyang Technological University

    9. Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope

      Explore BJO Online Ophthalmology
      Comparison of retinal vessel diameter measurements from swept-source OCT angiography and adaptive optics ophthalmoscope
      Background/ims To compare the retinal vessel diameter measurements obtained from the swept-source optical coherence tomography angiography (OCTA; Plex Elite 9000, Carl Zeiss Meditec, USA) and adaptive optics ophthalmoscope (AOO; RTX1, Imagine Eyes, France). Methods Fifteen healthy subjects, 67% women, mean age (SD) 30.87 (6.19) years, were imaged using OCTA and AOO by a single experienced operator on the same day. Each eye was scanned using two OCTA ...
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      Mentions: Medical University of Vienna Singapore Eye Research Institute Carl Zeiss Meditec

    10. Towards Indicating Human Skin State In Vivo Using Geometry-Dependent Spectroscopic Contrast Imaging

      Explore IEEE Xplore Dermatology
      Towards Indicating Human Skin State In Vivo Using Geometry-Dependent Spectroscopic Contrast Imaging
      Skin plays a significant role in human body function and its collagen states change during the human skin ageing process, which affects skin function. We previously reported on geometry-dependent spectroscopic contrast achieved by spectroscopic micro-optical coherence tomography ( S OCT), which discovered that transversely oriented and regularly arranged nano-cylinders selectively backscatter the long-wavelength lights and generate spectral centroid (SC) shifts towards the long wavelengths within a spectral window of 700 950 ...
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      Mentions: Nanyang Technological University Linbo Liu

    11. Real-time en-face Gabor optical coherence tomographic angiography on human skin using CUDA GPU

      Explore OSA | OSA Publishing
      Real-time en-face Gabor optical coherence tomographic angiography on human skin using CUDA GPU
      We recently proposed an optical coherence tomographic angiography (OCTA) algorithm, Gabor optical coherence tomographic angiography (GOCTA), which can extract microvascular signals from a spectral domain directly with lower computational complexity compared to other algorithms. In this manuscript, we combine a programmable swept source, an OCT complex signal detecting unit, and graphics process units (GPU) to achieve a real-time en-face GOCTA system for human skin microvascular imaging. The programmable swept source ...
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      Mentions: University of Toronto University of Washington Sunnybrook Health Sciences Centre

    12. Automatic differentiation of nonkeratinized stratified squamous epithelia and columnar epithelia through feature structure extraction using OCT

      Explore ScienceDirect Gastroenterology
      Automatic differentiation of nonkeratinized stratified squamous epithelia and columnar epithelia through feature structure extraction using OCT
      As a type of precancerous lesion, metaplasia is usually considered to be associated with developing cancer. In clinical practice, surveillance of metaplastic cases usually relies on excisional biopsy followed by histological processing and analysis. As it is an invasive method accompanied by other complications, non-invasive imaging methods such as optical coherence tomography (OCT) can complement the existing method by enabling large area scanning. However, because it takes time to review ...
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      Mentions: Nanyang Technological University Linbo Liu

    13. Postdoctoral Research Fellow In Ocular Imaging Program at the Singapore Eye Research Institute

      Explore Optical Coherence Tomography News Ophthalmology , Jobs & Studentships
      Postdoctoral Research Fellow In Ocular Imaging Program at the Singapore Eye Research Institute
      ... research programmes for eye diseases. Recently SERI has established an ocular imaging program together with Nanyang Technological University (NTU) under the directorship of Prof. Leopold Schmetterer. SERI is seeking a ...
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      Mentions: Singapore Eye Research Institute Nanyang Technological University

    15. Extending depth range of optical coherence tomography (Thesis)

      Explore DR-NTU HOME Student Theses
      Extending depth range of optical coherence tomography (Thesis)
      Optical coherence tomography (OCT) is a noninvasive diagnostic imaging tool that has been established in various clinical fields. One of the most cited issue of OCT in clinical practices is the shortage of image depth range. This thesis proposes four novel techniques to significantly extend the depth range without compromising other imaging performances. The OCT depth range is fundamentally limited by two main factors, which are the axial field of ...
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      Mentions: Nanyang Technological University

    16. Resolution enhancement and realistic speckle recovery with generative adversarial modeling of micro-optical coherence tomography

      Explore arxiv.org
      Resolution enhancement and realistic speckle recovery with generative adversarial modeling of micro-optical coherence tomography
      A resolution enhancement technique for optical coherence tomography (OCT), based on Generative Adversarial Networks (GANs), was developed and investigated. GANs have been previously used for resolution enhancement of photography and optical microscopy images. We have adapted and improved this technique for OCT image generation. Conditional GANs (cGANs) were trained on a novel set of ultrahigh resolution spectral domain OCT volumes, termed micro-OCT, as the high-resolution ground truth (1 m isotropic ...
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      Mentions: Nanyang Technological University Linbo Liu
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  4. About Nanyang Technological University

    Nanyang Technological University

    Nanyang Technological University (NTU is an internationally reputed research-intensive tertiary institution. Our broad-based education covers science and technology, business and the arts, entrepreneurial and leadership skills to prepare students for the global working world.

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