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    1. Mentioned In 93 Articles

    2. Optical coherence tomography with gapped spectrum

      Optical coherence tomography with gapped spectrum
      The axial resolution of optical coherence tomography (OCT) is determined by the spectral shape and bandwidth of the detected light, which are limited by the gaps in the wavelength range of illumination, transmission, and detection. In this work, we demonstrate that the axial resolution deteriorated by gaps in OCT spectra can be restored by adopting the gapped amplitude and phase estimation (GAPES) method. GAPES estimates the missing parts between separated ...
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    3. Nondestructive Measurement of Conformal Coating Thickness on Printed Circuit Board with Ultra-high Resolution Optical Coherence Tomography

      Nondestructive Measurement of Conformal Coating Thickness on Printed Circuit Board with Ultra-high Resolution Optical Coherence Tomography
      Conformal coating (CC) is widely used to protect printed circuit board (PCB) from corrosion, mould growth and electrical failures. To ensure an effective protection, the thickness of the conformal coating layer needs to be well controlled. However, to date, the coating thickness is usually measured in a destructive way under microscopes. In this study, we proposed to use optical coherence tomography (OCT) to measure the CC thickness nondestructively. Specifically, to ...
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    4. Cake formation of bidisperse suspensions in dead-end microfiltration

      Cake formation of bidisperse suspensions in dead-end microfiltration
      The evolution of the cake during dead-end microfiltration of different compositions of bidisperse feeds was investigated using network modeling and three-dimensional (3D) optical coherence tomography (OCT) imaging. The foulant particles were latex of two different sizes (namely, 3 and 5 m) and the membrane was polycarbonate track-etched with nominal diameter of 2 m. The results from the network model indicate that (i) the deposition of the smaller particles on the ...
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    5. Cellular resolution corneal imaging with extended imaging range

      Cellular resolution corneal imaging with extended imaging range
      Current optical coherence tomography (OCT) technology, which is used for imaging the eyes anterior segment, has been established as a clinical gold standard for the diagnosis of corneal diseases. However, the cellular resolution level information that is critical for many clinical applications is still not available. The major technical challenges toward cellular resolution OCT imaging are the limited ranging depth and depth of focus (DOF). In this work, we present ...
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    6. Development of cellular resolution optical coherence tomography (Thesis)

      Development of cellular resolution optical coherence tomography (Thesis)
      Diagnosis of most mucosal diseases including epithelial cancers relies on white-light endoscopy/visual inspection followed by random biopsy and histologic examination. These current standard-of-care tools are associated with many issues such as sampling errors, tissue destruction, and processing artifacts. In addition, it is too traumatic to take a biopsy from tissues like eyes and coronary arteries. Being high resolution, high speed, and non-invasive, optical coherence tomography (OCT) has emerged as ...
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    7. Quantitative analysis of choriocapillaris in non-human primates using swept-source optical coherence tomography angiography (SS-OCTA)

      Quantitative analysis of choriocapillaris in non-human primates using swept-source optical coherence tomography angiography (SS-OCTA)
      The choriocapillaris is a unique vascular plexus located posterior to the retinal pigment epithelium. In recent years, there is an increasing interest in the examination of the interrelationship between the choriocapillaris and eye diseases. We used several techniques to study choroidal perfusion, including laser Doppler flowmetry, laser speckle flowgraphy, and optical coherence tomography angiography (OCTA), but with the latter no standardized algorithm for quantitative analysis has been provided. We analyzed ...
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    8. Estimation of refractive index for biological tissue using micro-optical coherence tomography

      Estimation of refractive index for biological tissue using micro-optical coherence tomography
      The refractive index of biological tissue is required for investigating the tissue's optical properties. Efforts have been made to characterize refractive indices of biological tissues at a single wavelength, but it is more convenient to know the Cauchy's coefficients, which provide refractive index over a wide range of wavelengths. We demonstrate a method to noninvasively provide the Cauchy's dispersion coefficients of biological tissues using micro-optical coherence tomography ...
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    9. Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples

      Deep learning architecture “LightOCT” for diagnostic decision support using optical coherence tomography images of biological samples
      Optical coherence tomography (OCT) is being increasingly adopted as a label-free and non-invasive technique for biomedical applications such as cancer and ocular disease diagnosis. Diagnostic information for these tissues is manifest in textural and geometric features of the OCT images which are used by human expertise to interpret and triage. However, it suffers delays due to long process of conventional diagnostic procedure and shortage of human expertise. Here, a custom ...
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    10. Imaging cellular structures of atherosclerotic coronary arteries using circumferentially scanning micro-optical coherence tomography fiber probe ex vivo

      Imaging cellular structures of atherosclerotic coronary arteries using circumferentially scanning micro-optical coherence tomography fiber probe ex vivo
      Development and progression of coronary atherosclerotic lesions is mediated by a number of cellular components, which are not readily visualized using the current clinical investigation tools. Visualizing these cellular components in situ and in vivo may allow early detection of the vulnerable plaques, with implications for coronary artery disease (CAD) therapy and for the prevention of acute myocardial infarction (AMI). In this study, we have developed a fiber-optic micro-optical coherence ...
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    11. Artificial intelligence and deep learning in ophthalmology

      Artificial intelligence and deep learning in ophthalmology
      Artificial intelligence (AI) based on deep learning (DL) has sparked tremendous global interest in recent years. DL has been widely adopted in image recognition, speech recognition and natural language processing, but is only beginning to impact on healthcare. In ophthalmology, DL has been applied to fundus photographs, optical coherence tomography and visual fields, achieving robust classification performance in the detection of diabetic retinopathy and retinopathy of prematurity, the glaucoma-like disc ...
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    12. Comparison of Optical Coherence Tomography Angiography to Indocyanine Green Angiography and Slit Lamp Photography for Corneal Vascularization in an Animal Model

      Comparison of Optical Coherence Tomography Angiography to Indocyanine Green Angiography and Slit Lamp Photography for Corneal Vascularization in an Animal Model
      Corneal neovascularization (CoNV) could be treated by novel anti-angiogenic therapies, though reliable and objective imaging tools to evaluate corneal vasculature and treatment efficacy is still lacking. Optical coherence tomography angiography (OCTA) currently designed as a retinal vascular imaging system has been recently adapted for anterior-segment and showed good potential for successful imaging of CoNV. However, further development requires an animal model where parameters can be studied more carefully with histological ...
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    13. Novel application of In Vivo Micro-Optical Coherence Tomography to assess Cornea scarring in an Animal Model

      Novel application of In Vivo Micro-Optical Coherence Tomography to assess Cornea scarring in an Animal Model
      This pilot study uses a micro-optical coherence tomography (micro-OCT) system with ~1m axial resolution specifically to image the cornea and corneal scars in vivo . We used an established murine corneal scar model by irregular phototherapeutic keratectomy in ten C57BL/6 mice, with serial imaging using the micro-OCT and compared to anterior segment (AS-OCT) (RTvue, Optovue, Fremont, CA) before and after scar induction. Main outcome was agreement between the AS-OCT and ...
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    14. Extending the depth of focus of fiber-optic optical coherence tomography using a chromatic dual-focus design

      Extending the depth of focus of fiber-optic optical coherence tomography using a chromatic dual-focus design
      We report a dual-focus fiber-optic probe designed to extend depth of focus (DOF) in high-resolution endoscopic optical coherence tomography. We exploited the broad spectral bandwidth of a supercontinuum source and, in the fiber probe, the foci of the 7501000 nm and 11001450 nm inputs were axially chromatically shifted. The interference signals from the two spectral bands were measured with a Si camera-based spectrometer and an InGaAs camera-based spectrometer, respectively. We ...
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    15. Postdoctoral Research Fellow Position in the Ocular Imaging Program at the Singapore Eye Research Institute

      Postdoctoral Research Fellow Position in the Ocular Imaging Program at the Singapore Eye Research Institute
      ... research programmes for eye diseases. Recently SERI has established an ocular imaging program together with Nanyang Technological University (NTU) under the directorship of Prof. Leopold Schmetterer. SERI is seeking a ...
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    16. 1-15 of 93 1 2 3 4 5 6 7 »
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  2. About Nanyang Technological University

    Nanyang Technological University

    Nanyang Technological University (NTU is an internationally reputed research-intensive tertiary institution. Our broad-based education covers science and technology, business and the arts, entrepreneurial and leadership skills to prepare students for the global working world.