1. Nankai University

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    1. Mentioned In 31 Articles

    2. Digital refocusing based on deep learning in optical coherence tomography

      Digital refocusing based on deep learning in optical coherence tomography
      We present a deep learning-based digital refocusing approach to extend depth of focus for optical coherence tomography (OCT) in this paper. We built pixel-level registered pairs of en face low-resolution (LR) and high-resolution (HR) OCT images based on experimental data and introduced the receptive field block into the generative adversarial networks to learn the complex mapping relationship between LR-HR image pairs. It was demonstrated by results of phantom and biological ...
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    3. Detection of retinal changes with optical coherence tomography angiography in mild cognitive impairment and Alzheimer's disease patients: A meta-analysis

      Detection of retinal changes with optical coherence tomography angiography in mild cognitive impairment and Alzheimer's disease patients: A meta-analysis
      Objective To assess retinal microvascular network impairments in the eyes of mild cognitive impairment (MCI) and Alzheimers disease (AD) patients with optical coherence tomography angiography (OCTA). Design Systematic review and meta-analysis. Methods A literature search was conducted in the PubMed and EMBASE databases to identify relevant studies detecting retinal microvascular attenuation among AD, MCI patients and cognitively healthy controls (HCs) by OCTA. Data were extracted by Review Manager V.5 ...
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    4. Identification of oral precancerous and cancerous tissue by swept source optical coherence tomography

      Identification of oral precancerous and cancerous tissue by swept source optical coherence tomography
      Background and objectives: Distinguishing cancer from precancerous lesions is critical and challenging in oral medicine. As a noninvasive method, optical coherence tomography (OCT) has the advantages of real-time, in vivo, and large-depth imaging. Texture information hidden in OCT images can provide an important auxiliary effect for improving diagnostic accuracy. The aim of this study is to explore a reliable and accurate OCT-based method for the screening and diagnosis of human ...
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    5. Classification of oral salivary gland tumors based on texture features in optical coherence tomography images

      Classification of oral salivary gland tumors based on texture features in optical coherence tomography images
      Currently, the diagnoses of oral diseases primarily depend on the visual recognition of experienced clinicians. It has been proven that automatic recognition based on images can support clinical decision-making by extracting and analyzing objective hidden information. In recent years, optical coherence tomography (OCT) has become a powerful optical imaging technique with the advantages of high resolution and non-invasion. In our study, a dataset composed of four kinds of oral salivary ...
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    6. A spatial resolution evaluation method of endoscopic optical coherence tomography system using the annular phantom

      A spatial resolution evaluation method of endoscopic optical coherence tomography system using the annular phantom
      As an important biomedical imaging method, endoscopic optical coherence tomography (OCT) is necessary to check its performance regularly. The ordinary plane phantoms are only able to evaluate part of image tangent to the probe. In this research, a spatial resolution estimate method of the endoscope OCT system is proposed. The annular phantom, made by uniformly distributing golden scattered microparticles in polydimethylsiloxane (PDMS), can provide dynamic scanning imaging evaluation of endoscopic ...
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    7. Perinatal risk factors associated with central retinal changes in former preterm children on optical coherence tomography angiography

      Perinatal risk factors associated with central retinal changes in former preterm children on optical coherence tomography angiography
      To analyze the relationships between the fixation location and the visual function of idiopathic macular hole (IMH) patients with macular integrity assessment (MAIA) examination preoperatively and 3 months postoperatively. This was a retrospective case analysis. Forty-three eyes of 43 patients diagnosed with IMH were included in this study. The best corrected visual acuity (BCVA) assessments, optical coherence tomography (OCT) and MAIA examinations were performed before surgery and 1 week, 1 ...
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    8. Classification of Salivary Gland Tumors Based on Quantitative Optical Coherence Tomography

      Classification of Salivary Gland Tumors Based on Quantitative Optical Coherence Tomography
      Background and Objectives Visual inspection is the primary diagnostic method for oral diseases, and its accuracy of diagnosis mainly depends on surgeons experience. Histological examination is still the golden standard, but it is invasive and time‐consuming. In order to address these issues, as a noninvasive imaging technique, optical coherence tomography (OCT) can differentiate oral tissue with advantages of real‐time, in situ , and high resolution. The aim of this ...
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    9. Identifying Diabetic Macular Edema and Other Retinal Diseases by Optical Coherence Tomography Image and Multiscale Deep Learning

      Identifying Diabetic Macular Edema and Other Retinal Diseases by Optical Coherence Tomography Image and Multiscale Deep Learning
      ... People’s Republic of China; 2Tianjin Key Laboratory of Optoelectronic Sensor and Sensing Network Technology, Nankai University, Tianjin 300350, People’s Republic of China; 3College of Computer Science, Nankai University...
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    10. High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging

      High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging
      Zebrafish are an important animal model, whose structure and function information can be used to study development, pathologic changes and genetic mutations. However, limited by the penetration depth, the available optical methods are difficult to image the whole-body zebrafish in juvenile and adult stages. Based on a home-made high-resolution polarization-sensitive optical coherence tomography (PS-OCT) system, we finished in vivo volumetric imaging for zebrafish, and various muscles can be clearly discerned ...
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    11. Multimodal imaging with integrated auto-fluorescence and optical coherence tomography for identification of neck tissues

      Multimodal imaging with integrated auto-fluorescence and optical coherence tomography for identification of neck tissues
      We report a multimodal optical system by combining OCT with autofluorescence imaging for identifying neck tissues, which can use the advantages of large field of view and high sensitivity for identifying parathyroid glands of fluorescence imaging, and high-resolution structural imaging of OCT to confirm them and identify lymph nodes and metastatic lymph nodes at the same time. It is proven that this multimodal optical system can be used to identify ...
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    12. Identification of oral cancer in OCT images based on an optical attenuation model

      Identification of oral cancer in OCT images based on an optical attenuation model
      Surgery is still the first choice to treat oral cancer, where it is important to detect surgical margins in order to reduce cancer recurrence and maintain oral-maxillofacial function simultaneously. As a non-invasive and in situ imaging technique, optical coherence tomography (OCT) can obtain images close to the resolution of histopathology, which makes it have great potential in intraoperative diagnosis. However, it is not enough to find surgical margins accurately just ...
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    13. Low-cost, ultracompact handheld optical coherence tomography probe for in vivo oral maxillofacial tissue imaging

      Low-cost, ultracompact handheld optical coherence tomography probe for in vivo oral maxillofacial tissue imaging
      Significance: Optical coherence tomography (OCT) has proven useful for detecting various oral maxillofacial abnormalities. To apply it to clinical applications including biopsy guidance and routine screening, a handheld imaging probe is indispensable. OCT probes reported for oral maxillofacial imaging were either based on a bulky galvanometric mirror pair (not compact or long enough) or a distal-end microelectromechanical systems (MEMS) scanner (raised safety concerns), or adapted from fiber-optic catheters (ill-suited for ...
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    14. Robust, accurate depth-resolved attenuation characterization in optical coherence tomography

      Robust, accurate depth-resolved attenuation characterization in optical coherence tomography
      Depth-resolved optical attenuation coefficient is a valuable tissue parameter that complements the intensity-based structural information in optical coherent tomography (OCT) imaging. Herein we systematically analyzed the under- and over-estimation bias of existing depth-resolved methods when applied to real biological tissues, and then proposed a new algorithm that remedies these issues and accommodates general OCT data that contain incomplete decay and noise floor, thereby affording consistent estimation accuracy for practical biological ...
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    15. Detection of laser-induced bulk damage in optical crystals by swept-source optical coherence tomography

      Detection of laser-induced bulk damage in optical crystals by swept-source optical coherence tomography
      An approach to characterize laser-induced bulk damage in optical crystal materials was demonstrated. With a homemade swept-source optical coherence tomography (SS-OCT) system, we obtained three-dimensional images of the bulk damage produced by laser pulses with wavelength of 351 nm, pulse width of 5 ns, beam diameter of 5.5 mm and fluences from 4.56 J/cm 2 to 9.95 J/cm 2 in Potassium Dihydrogen Phosphate (KDP) crystal ...
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    16. Ultrafast Wavenumber Linear-step-swept source Based on Synchronous Lightwave Synthesized Frequency Sweeper

      Ultrafast Wavenumber Linear-step-swept source Based on Synchronous Lightwave Synthesized Frequency Sweeper
      An ultrafast wavenumber linear-step-swept source based on a synchronous lightwave synthesized frequency sweeper (SLSFS) is demonstrated. A multi-wavelength source is used as a seed source. In SLSFS, the swept range of different wavelength components is precisely controlled by a stable programmable radio frequency (RF) signal applied on a dual-parallel Mach-Zehnder modulator (DP-MZM) instead of a conventional wavelength filter. The identical frequency shifting step of all the wavelength components promises high ...
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  2. About Nankai University

    Nankai University

    Nankai University is a key multidisciplinary and research-oriented university directly under the jurisdiction of the Ministry of Education, Nankai University,located in Tianjin on the border of the sea of Bohai, is also the alma mater of our beloved late Premier Zhou Enlai. Nankai University was founded in 1919 by the famous patriotic educators, Mr. Zhang Boling and Mr. Yan Xiu. During the Anti-Japanese war (1937-1945), Nankai University, Peking University (Beijng University) and Tsinghua University (Qinghua University) united in Kunming to form the renowned Southwest Associated University.