1. Nankai University

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    1. Mentioned In 23 Articles

    2. High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging

      High-resolution polarization-sensitive optical coherence tomography for zebrafish muscle imaging
      Zebrafish are an important animal model, whose structure and function information can be used to study development, pathologic changes and genetic mutations. However, limited by the penetration depth, the available optical methods are difficult to image the whole-body zebrafish in juvenile and adult stages. Based on a home-made high-resolution polarization-sensitive optical coherence tomography (PS-OCT) system, we finished in vivo volumetric imaging for zebrafish, and various muscles can be clearly discerned ...
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    3. Multimodal imaging with integrated auto-fluorescence and optical coherence tomography for identification of neck tissues

      Multimodal imaging with integrated auto-fluorescence and optical coherence tomography for identification of neck tissues
      We report a multimodal optical system by combining OCT with autofluorescence imaging for identifying neck tissues, which can use the advantages of large field of view and high sensitivity for identifying parathyroid glands of fluorescence imaging, and high-resolution structural imaging of OCT to confirm them and identify lymph nodes and metastatic lymph nodes at the same time. It is proven that this multimodal optical system can be used to identify ...
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    4. Identification of oral cancer in OCT images based on an optical attenuation model

      Identification of oral cancer in OCT images based on an optical attenuation model
      Surgery is still the first choice to treat oral cancer, where it is important to detect surgical margins in order to reduce cancer recurrence and maintain oral-maxillofacial function simultaneously. As a non-invasive and in situ imaging technique, optical coherence tomography (OCT) can obtain images close to the resolution of histopathology, which makes it have great potential in intraoperative diagnosis. However, it is not enough to find surgical margins accurately just ...
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    5. Low-cost, ultracompact handheld optical coherence tomography probe for in vivo oral maxillofacial tissue imaging

      Low-cost, ultracompact handheld optical coherence tomography probe for in vivo oral maxillofacial tissue imaging
      Significance: Optical coherence tomography (OCT) has proven useful for detecting various oral maxillofacial abnormalities. To apply it to clinical applications including biopsy guidance and routine screening, a handheld imaging probe is indispensable. OCT probes reported for oral maxillofacial imaging were either based on a bulky galvanometric mirror pair (not compact or long enough) or a distal-end microelectromechanical systems (MEMS) scanner (raised safety concerns), or adapted from fiber-optic catheters (ill-suited for ...
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    6. Robust, accurate depth-resolved attenuation characterization in optical coherence tomography

      Robust, accurate depth-resolved attenuation characterization in optical coherence tomography
      Depth-resolved optical attenuation coefficient is a valuable tissue parameter that complements the intensity-based structural information in optical coherent tomography (OCT) imaging. Herein we systematically analyzed the under- and over-estimation bias of existing depth-resolved methods when applied to real biological tissues, and then proposed a new algorithm that remedies these issues and accommodates general OCT data that contain incomplete decay and noise floor, thereby affording consistent estimation accuracy for practical biological ...
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    7. Detection of laser-induced bulk damage in optical crystals by swept-source optical coherence tomography

      Detection of laser-induced bulk damage in optical crystals by swept-source optical coherence tomography
      An approach to characterize laser-induced bulk damage in optical crystal materials was demonstrated. With a homemade swept-source optical coherence tomography (SS-OCT) system, we obtained three-dimensional images of the bulk damage produced by laser pulses with wavelength of 351 nm, pulse width of 5 ns, beam diameter of 5.5 mm and fluences from 4.56 J/cm 2 to 9.95 J/cm 2 in Potassium Dihydrogen Phosphate (KDP) crystal ...
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    8. Ultrafast Wavenumber Linear-step-swept source Based on Synchronous Lightwave Synthesized Frequency Sweeper

      Ultrafast Wavenumber Linear-step-swept source Based on Synchronous Lightwave Synthesized Frequency Sweeper
      An ultrafast wavenumber linear-step-swept source based on a synchronous lightwave synthesized frequency sweeper (SLSFS) is demonstrated. A multi-wavelength source is used as a seed source. In SLSFS, the swept range of different wavelength components is precisely controlled by a stable programmable radio frequency (RF) signal applied on a dual-parallel Mach-Zehnder modulator (DP-MZM) instead of a conventional wavelength filter. The identical frequency shifting step of all the wavelength components promises high ...
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    9. Optical clearing for luminal organ imaging with ultrahigh-resolution optical coherence tomography

      Optical clearing for luminal organ imaging with ultrahigh-resolution optical coherence tomography
      The imaging depth of optical coherence tomography (OCT) in highly scattering biological tissues (such as luminal organs) is limited, particularly for OCT operating at shorter wavelength regions (such as around 800nm). For the first time, the optical clearing effect of the mixture of liquid paraffin and glycerol on luminal organs was explored with ultrahigh-resolution spectral domain OCT at 800nm.Ex vivostudies were performed on pig esophagus and bronchus, and guinea ...
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    10. Scattering coefficients of mice organs categorized pathologically by spectral domain optical coherence tomography

      Scattering coefficients of mice organs categorized pathologically by spectral domain optical coherence tomography
      Differences in tissue density cause a variety of scattering coefficients. To quantify optical coherence tomography (OCT) images for diagnosis, the tissue's scattering coefficient is estimated by curve fitting the OCT signals to a confocal single backscattering mode. The results from a group of 30 mice show that the scattering coefficients of bone, skin, liver, brain, testis, and spleen can be categorized into three groups: a scattering coefficient between 1 ...
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    11. Quantitative Diagnosis of Colorectal Polyps by Spectral Domain Optical Coherence Tomography

      Quantitative Diagnosis of Colorectal Polyps by Spectral Domain Optical Coherence Tomography
      The principal aim of this study is to investigate the scattering coefficient of colorectal polyp tissues using an optical coherence tomography (OCT) technique. It combines the existing scattering coefficient model and spectral domain OCT to achieve method of early diagnosis of colorectal polyp in hospitals. Seventeen patients were studied, and a total of 1456 data points were extracted by curve-fitting the OCT signals into a confocal single-backscattering model. The results ...
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    12. 1-15 of 23 1 2 »
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  2. About Nankai University

    Nankai University

    Nankai University is a key multidisciplinary and research-oriented university directly under the jurisdiction of the Ministry of Education, Nankai University,located in Tianjin on the border of the sea of Bohai, is also the alma mater of our beloved late Premier Zhou Enlai. Nankai University was founded in 1919 by the famous patriotic educators, Mr. Zhang Boling and Mr. Yan Xiu. During the Anti-Japanese war (1937-1945), Nankai University, Peking University (Beijng University) and Tsinghua University (Qinghua University) united in Kunming to form the renowned Southwest Associated University.