1. Nanjing University of Science and Technology

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    1. Mentioned In 36 Articles

    2. Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity

      Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity
      ims: A novel method for computation of fractional flow reserve (FFR) from optical coherence tomography (OCT) was developed recently. This study aimed to evaluate the diagnostic accuracy of a new OCT-based FFR (OFR) computational approach, using wire-based FFR as the reference standard. Methods and results: Patients who underwent both OCT and FFR prior to intervention were analysed. The lumen of the interrogated vessel and the ostia of the side branches ...
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    3. OCT angiography-based monitoring of neovascular regression on fibrovascular membrane after preoperative intravitreal conbercept injection

      OCT angiography-based monitoring of neovascular regression on fibrovascular membrane after preoperative intravitreal conbercept injection
      Purpose To quantify the preoperative neovascular change pattern on the fibrovascular membrane (FVM) within 7 days after intravitreal injection of conbercept (IVC) using optical coherence tomography angiography (OCTA) in proliferative diabetic retinopathy (PDR). Methods Prospective, observational study of PDR patients with visible FVM receiving or not receiving IVC. Neovascular changes were assessed by OCTA pre-IVC and 1, 3, 5, and 7 days post-IVC. Vessel skeleton density (SD) and vessel density ...
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    4. 2D MEMS-based high-speed beam-shifting technique for speckle noise reduction and flow rate measurement in optical coherence tomography

      2D MEMS-based high-speed beam-shifting technique for speckle noise reduction and flow rate measurement in optical coherence tomography
      In this manuscript, a two-dimensional (2D) micro-electro-mechanical system (MEMS)-based, high-speed beam-shifting spectral domain optical coherence tomography (MHB-SDOCT) is proposed for speckle noise reduction and absolute flow rate measurement. By combining a zigzag scanning protocol, the frame rates of 45.2 Hz for speckle reduction and 25.6 Hz for flow rate measurement are achieved for in-vivo tissue imaging. Phantom experimental results have shown that by setting the incident beam ...
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    5. Measurement and compensation of motion artifacts in spectral domain optical coherence tomography

      Measurement and compensation of motion artifacts in spectral domain optical coherence tomography
      Spectral domain optical coherence tomography (SDOCT) has the capability of generating optical sectioning images at high depth resolution in vivo, which is helpful for the diagnosis of various disease. But when the voluntary and involuntary movement of the sample occurs during the acquisition time, the real structure of the sample will be distorted. So it is valuable to compensate the motion artifacts in SDOCT imaging to obtain high quality images ...
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    6. All single-mode fiber-based polarization-sensitive spectral domain optical coherence tomography system

      All single-mode fiber-based polarization-sensitive spectral domain optical coherence tomography system
      We reported an all single-mode fiber (SMF)-based polarization sensitive spectral domain optical coherence tomography (PSSDOCT) system with single input polarization state (IPS). In our design, polarization state was modulated only by four polarization controllers (PC) and a polarization beam splitter. To extract the phase retardance and optical axis orientation of sample, the Mueller matrix of the fiber system and sample is transferred to a new retardar by employing PCs ...
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    7. Single-shot wavelength-independent phase-shifting method for full-field optical coherence tomography

      Single-shot wavelength-independent phase-shifting method for full-field optical coherence tomography
      One limitation of a piezoelectric translator-based phase-shifting method in full-field optical coherence tomography (FF-OCT) is that there exist interference residuals because a light source with broadband is used. In this work, an achromatic phase-shifting method was proposed in which a linear polarizer and a quarter-wave plate were employed to generate the circularly polarized light in the reference arm of a basic Linnik interferometer. The light field reflected from the reference ...
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    8. Diagnosis and treatment evaluation of in-stent restenosis of carotid artery stenting using optical coherence tomography

      Diagnosis and treatment evaluation of in-stent restenosis of carotid artery stenting using optical coherence tomography
      A 65-year-old man underwent balloon angioplasty and repeat carotid artery stenting (CAS) due to in-stent restenosis (ISR). Intravascular optical coherence tomography (OCT) showed a severe ISR with fibrotic neointimal growth ( figure 1 ). Post 6.0 30 mm balloon angioplasty, OCT showed intimal disruption and artery dissection ( figure 2 ). After the 8 40 mm stent fully expanded, OCT showed stent struts well apposed, but tissue protrusion from the spaces between stent ...
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    9. Beam-shifting technique for speckle reduction and flow rate measurement in optical coherence tomography

      Beam-shifting technique for speckle reduction and flow rate measurement in optical coherence tomography
      In this Letter, we propose a beam-shifting optical coherence tomography scheme for speckle reduction and blood flow rate calculation, where variations of the speckle pattern and Doppler angle were generated by parallel shifting of the sample beam incident on the objective lens. The resultant optical coherent tomography images could then be averaged for speckle noise reduction and simultaneously analyzed for flow rate measurement. The performance of the proposed technique was ...
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    10. Buffer-averaging super-continuum source based spectral domain optical coherence tomography for high speed imaging

      Buffer-averaging super-continuum source based spectral domain optical coherence tomography for high speed imaging
      In super-continuum (SC) source based spectral domain optical coherence tomography (SC-SDOCT), the stability of the power spectral density (PSD) has a significant impact on OCT system sensitivity and image signal to noise ratio (SNR). High speed imaging decreases the camera's exposure time, thus each A-scan contained fewer laser pulse excited SC wideband emissions, resulting in a decrease of SNR. In this manuscript, we present a buffer-averaging SC-SDOCT (BASC-SDOCT) to ...
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    11. Automated segmentation of hyperreflective foci in spectral domain optical coherence tomography with diabetic retinopathy

      Automated segmentation of hyperreflective foci in spectral domain optical coherence tomography with diabetic retinopathy
      We propose an automated segmentation method to detect, segment, and quantify hyperreflective foci (HFs) in three-dimensional (3-D) spectral domain optical coherence tomography (SD-OCT). The algorithm is divided into three stages: preprocessing, layer segmentation, and HF segmentation. In this paper, a supervised classifier (random forest) was used to produce the set of boundary probabilities in which an optimal graph search method was then applied to identify and produce the layer segmentation ...
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    12. Automatic Subretinal Fluid Segmentation of Retinal SD-OCT Images With Neurosensory Retinal Detachment Guided by Enface Fundus Imaging

      Automatic Subretinal Fluid Segmentation of Retinal SD-OCT Images With Neurosensory Retinal Detachment Guided by Enface Fundus Imaging
      Objective: Accurate segmentation of neurosensory retinal detachment (NRD) associated subretinal fluid in spectral domain optical coherence tomography (SD-OCT) is vital for the assessment of central serous chorioretinopathy (CSC). A novel two-stage segmentation algorithm was proposed, guided by Enface fundus imaging. Methods: In the first stage, Enface fundus image was segmented using thickness map prior to detecting the fluid-associated abnormalities with diffuse boundaries. In the second stage, the locations of the ...
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    13. Quantitative measurement of subsurface damage with self-referenced spectral domain optical coherence tomography

      Quantitative measurement of subsurface damage with self-referenced spectral domain optical coherence tomography
      In this work, we present the three-dimensional reconstruction of the subsurface damage (SSD) within the optical components at the level of several microns with a self-referenced spectral domain optical coherence tomography (SDOCT) system, from which the quantitative information, including the maximum depth, the cluster depth, the shape, the size and the damage density, can be acquired. First, to compare the actual maximum depths with the ones computed by the formulas ...
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    14. In vivo assessment of macula in eyes of healthy children 8 to 16 years old using optical coherence tomography angiography

      In vivo assessment of macula in eyes of healthy children 8 to 16 years old using optical coherence tomography angiography
      The purpose of the present study was to investigate the vascular flow density (VD) of macular superficial (SCP), deep capillary plexus (DCP), and choriocapillaris and the size of the foveal avascular zone (FAZ) area in healthy children using optical coherence tomography angiography (OCTA). The potential associations of age, sex, intraocular pressure, body mass index, spherical equivalent, and axial length with OCTA parameters were also investigated. A total of 75 eyes ...
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    15. Optimization of linear-wavenumber spectrometer for high-resolution spectral domain optical coherence tomography

      Optimization of linear-wavenumber spectrometer for high-resolution spectral domain optical coherence tomography
      Nonlinear detection of the spectral interferograms in wavenumber ( k ) space degrades the depth-dependent signal sensitivity in conventional linear-in- spectrometer based spectral domain optical coherence tomography (SDOCT). Linear- k spectrometer enables high sensitivity SDOCT imaging without the need of resampling the digitized non-linear-in- k data. Here we report an effective optimization method for linear- k spectrometer used in a high-resolution SDOCT system. The design parameters of the linear- k spectrometer, including ...
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    16. Quantitative depth resolved microcirculation imaging with optical coherence tomography angiography (Part Ι): Blood flow velocity imaging

      Quantitative depth resolved microcirculation imaging with optical coherence tomography angiography (Part Ι): Blood flow velocity imaging
      The research goal of the microvascular network imaging with optical coherence tomography (OCT) angiography is to achieve depth resolved blood flow and vessel imaging in vivo in the clinical management of patents. In this review, we review the main phenomena that have been explored in OCT to image the blood flow velocity vector and the vessels of the microcirculation within living tissues. Parameters that limit the accurate measurements of blood ...
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    17. 1-15 of 36 1 2 3 »
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  2. About Nanjing University of Science and Technology

    Nanjing University of Science and Technology

    Nanjing University of Science and Technology (NUST) is one of the national key universities under the guidance of the Ministry of Industry and Information Technology. The university has more than sixty years' experience in providing inspiring and broadened-horizon education. It has become a multi-disciplinary university comprising academic fields including: science, engineering, liberal arts, economics, business, management, law and education. In addition, NUST encompasses a wide array of centers, institutes, programs, and administrative support offices.