1. Nanjing University of Science and Technology

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    1. Mentioned In 53 Articles

    2. Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study

      Superficial Calcification With Rotund Shape Is Associated With Carotid Plaque Rupture: An Optical Coherence Tomography Study
      Background: Plaque rupture is an important etiology for symptomatic carotid stenosis. The role of calcification in the plaque vulnerability has been controversial. We aimed to detect the geometric features of calcifications in carotid plaque and to examine its association with plaque rupture. Methods: Optical coherence tomography assessment of carotid plaque was performed in 88 patients. Calcification shape was evaluated through quantitative measurements of the long and short axis, area size ...
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    3. A theoretical model for the micron resolution spectral domain optical coherence tomography

      A theoretical model for the micron resolution spectral domain optical coherence tomography
      The resolution and effective imaging depth (EID) of spectral domain optical coherence tomography (OCT) are of great importance for visualizing the fine details of biological tissues. To this end, a theoretical model for the micron resolution spectral domain OCT was proposed with both the temporal coherence and the longitudinal spatial coherence considered. Based on the model, the parameters that influence the axial resolution, the signal intensity and the EID can ...
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    4. Fast and Automated Hyperreflective Foci Segmentation Based on Image Enhancement and Improved 3D U-Net in SD-OCT Volumes with Diabetic Retinopathy

      Fast and Automated Hyperreflective Foci Segmentation Based on Image Enhancement and Improved 3D U-Net in SD-OCT Volumes with Diabetic Retinopathy
      Purpose : To design a robust and automated hyperreflective foci (HRF) segmentation framework for spectral-domain optical coherence tomography (SD-OCT) volumes, especially volumes with low HRF-background contrast. Methods : HRF in retinal SD-OCT volumes appear with low-contrast characteristics that results in the difficulty of HRF segmentation. Therefore to effectively segment the HRF we proposed a fully automated method for HRF segmentation in SD-OCT volumes with diabetic retinopathy (DR). First, we generated the enhanced ...
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    5. Point spread function degradation model of a polarization imaging system for wide-field subwavelength nanoparticles

      Point spread function degradation model of a polarization imaging system for wide-field subwavelength nanoparticles
      We propose a comprehensive point spread function (PSF) degradation model, which considers multiple factors consisting of degradation of specimen retardant sampling and polarization angularly anamorphic sampling, to indicate the image degradation characteristics of polarization imaging systems. First, a one-layer optical coherence tomography (OCT) model was established to express the retardancy of medium-loading specimens. Then, a PSF degradation model of angularly anamorphic polarization sampling was deduced through the retrieval of Stokes ...
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    6. Cooperative low-rank models for removing stripe noise from OCTA images

      Cooperative low-rank models for removing stripe noise from OCTA images
      Optical coherence tomography angiography (OCTA) is an emerging non-invasive imaging technique for imaging the microvasculature of the eye based on phase variance or amplitude decorrelation derived from repeated OCT images of the same tissue area. Stripe noise occurs during the OCTA acquisition process due to the involuntary movement of the eye. To remove the stripe noise (or 'destriping') effectively, we propose two novel image decomposition models to simultaneously destripe all ...
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    7. Measurement of optic axis orientation with single-mode fiber-based polarization-sensitive optical coherence tomography

      Measurement of optic axis orientation with single-mode fiber-based polarization-sensitive optical coherence tomography
      An algorithm is presented that can be used to obtain accurate optic axis orientation of birefringent tissue samples. A single-mode fiber (SMF)-based polarization-sensitive optical coherence tomography with a single linearly polarized incident light was used in the measurements in which the light reflected from the sample and detected by the spectrometer is linearly polarized light at 45 deg with respect to the experimental horizontal axis. By employing polarization controllers ...
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    8. Ticagrelor versus clopidogrel for prevention of subclinical stent thrombosis detected by optical coherence tomography in patients with drug-eluting stent implantation—a multicenter and randomized study

      Ticagrelor versus clopidogrel for prevention of subclinical stent thrombosis detected by optical coherence tomography in patients with drug-eluting stent implantation—a multicenter and randomized study
      Introduction : This prospective, multicenter, randomized study was designed to analyze the benefits of ticagrelor over clopidogrel in reducing subclinical stent thrombosis (ST) in patients with coronary artery disease who underwent implantation of a second-generation drug-eluting stent (DES). Methods : About 352 patients with single de novo coronary stenosis were randomly assigne`d to either clopidogrel group (aspirin plus clopidogrel) or ticagrelor group (aspirin plus ticagrelor) after DES implantation for 1 year ...
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    9. Miniaturized precalibration-based Lissajous scanning fiber probe for high speed endoscopic optical coherence tomography

      Miniaturized precalibration-based Lissajous scanning fiber probe for high speed endoscopic optical coherence tomography
      We present a miniaturized precalibration-based forward-viewing Lissajous scanning fiber probe for high speed endoscopic optical coherence tomography (OCT). The probe is based on an asymmetric fiber cantilever driven by the piezoelectric bender to realize two-dimensional (2D) Lissajous scanning. The stability and repeatability of the Lissajous scanning trajectory of the probe is tested by a position sensitive detector (PSD)-based position calibration setup. The two orthogonal resonant frequencies of the cantilever ...
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    10. Optical coherence tomography evaluation of vertebrobasilar artery stenosis: case series and literature review

      Optical coherence tomography evaluation of vertebrobasilar artery stenosis: case series and literature review
      Background Intracranial vertebrobasilar artery stenosis is an important cause of ischemic stroke. With its high resolution, intravascular optical coherence tomography (OCT) provides detailed assessment of vessel wall features. It is widely applied to identify high-risk plaque in the cardiovascular system, but its use in the intracranial artery has been limited. Objective To explore, in this pilot study, the usefulness of OCT in imaging of the intracranial artery wall. Methods Between ...
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    11. FFOCT imaging based on compressed sensing

      FFOCT imaging based on compressed sensing
      With the demand for high-resolution images, the storage space occupied by the images of the full-field optical coherence tomography (FFOCT) system is becoming more and more intensified. How to reduce the data volume of high-resolution image systems has become a research hotspot in the image processing industry. In particular, precision medicine requires high-resolution images of organs and tissues, and this data storage system requires a large storage space. For this ...
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    12. Cholesterol Crystals are Associated with Carotid Plaque Vulnerability: An Optical Coherence Tomography Study

      Cholesterol Crystals are Associated with Carotid Plaque Vulnerability: An Optical Coherence Tomography Study
      Objective: Vulnerable carotid plaque is associated with cerebrovascular events. Cholesterol crystals are often seen in the atherosclerotic plaques. However, the potential role of cholesterol crystals in carotid plaques destabilization is unknown. We aimed to identify the association between cholesterol crystals and carotid plaque vulnerability. Methods: Optical coherence tomography assessment of carotid plaque was performed in 95 patients. Clinical characteristics and plaque morphology were examined. The differences in plaque characteristics (thrombus ...
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    13. Gabor optical coherence tomographic angiography (GOCTA) (Part II): theoretical basis of sensitivity improvement and optimization for processing speed

      Gabor optical coherence tomographic angiography (GOCTA) (Part II): theoretical basis of sensitivity improvement and optimization for processing speed
      We previously proposed a Gabor optical coherence tomography angiography (GOCTA) algorithm for spectral domain optical coherence tomography (SDOCT) to extract microvascular signals from spectral fringes directly, with speed improvement of 4 to 20 times over existing methods. In this manuscript, we explored the theoretical basis of GOCTA with comparison of experimental data using solid and liquid displacement sample targets, demonstrating that the majority of the GOCTA sensitivity advantage over speckle ...
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    14. Extended focus optical coherence tomography with Fresnel lens

      Extended focus optical coherence tomography with Fresnel lens
      We report a Fresnel lens based spectral domain optical coherence tomography (SDOCT) setup to overcome the trade-off between lateral resolution and focusing depth which is one of the main problems for OCT system. We demonstrated the feasibility of the Fresnel lens based SDOCT system by measuring the lateral resolution at different depth positions and compared these results with that obtained by conventional SDOCT illuminated with a light source of a ...
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    15. Geographic Atrophy Segmentation in SD-OCT Images Using Synthesized Fundus Autofluorescence Imaging

      Geographic Atrophy Segmentation in SD-OCT Images Using Synthesized Fundus Autofluorescence Imaging
      Background and Objective Accurate assessment of geographic atrophy (GA) is critical for diagnosis and therapy of non-exudative age-related macular degeneration (AMD). Herein, we propose a novel GA segmentation framework for spectral-domain optical coherence tomography (SD-OCT) images that employs synthesized fundus autofluorescence (FAF) images. Methods An en-face OCT image is created via the restricted sub-volume projection of three-dimensional OCT data. A GA region-aware conditional generative adversarial network is employed to generate ...
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    16. RETOUCH: The Retinal OCT Fluid Detection and Segmentation Benchmark and Challenge

      RETOUCH: The Retinal OCT Fluid Detection and Segmentation Benchmark and Challenge
      Retinal swelling due to the accumulation of fluid is associated with the most vision-threatening retinal diseases. Optical coherence tomography (OCT) is the current standard of care in assessing the presence and quantity of retinal fluid and image-guided treatment management. Deep learning methods have made their impact across medical imaging, and many retinal OCT analysis methods have been proposed. However, it is currently not clear how successful they are in interpreting ...
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  2. About Nanjing University of Science and Technology

    Nanjing University of Science and Technology

    Nanjing University of Science and Technology (NUST) is one of the national key universities under the guidance of the Ministry of Industry and Information Technology. The university has more than sixty years' experience in providing inspiring and broadened-horizon education. It has become a multi-disciplinary university comprising academic fields including: science, engineering, liberal arts, economics, business, management, law and education. In addition, NUST encompasses a wide array of centers, institutes, programs, and administrative support offices.