1. Nanjing University of Science and Technology

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    1. Mentioned In 48 Articles

    2. Measurement of optic axis orientation with single-mode fiber-based polarization-sensitive optical coherence tomography

      Measurement of optic axis orientation with single-mode fiber-based polarization-sensitive optical coherence tomography
      An algorithm is presented that can be used to obtain accurate optic axis orientation of birefringent tissue samples. A single-mode fiber (SMF)-based polarization-sensitive optical coherence tomography with a single linearly polarized incident light was used in the measurements in which the light reflected from the sample and detected by the spectrometer is linearly polarized light at 45 deg with respect to the experimental horizontal axis. By employing polarization controllers ...
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    3. Ticagrelor versus clopidogrel for prevention of subclinical stent thrombosis detected by optical coherence tomography in patients with drug-eluting stent implantation—a multicenter and randomized study

      Ticagrelor versus clopidogrel for prevention of subclinical stent thrombosis detected by optical coherence tomography in patients with drug-eluting stent implantation—a multicenter and randomized study
      Introduction : This prospective, multicenter, randomized study was designed to analyze the benefits of ticagrelor over clopidogrel in reducing subclinical stent thrombosis (ST) in patients with coronary artery disease who underwent implantation of a second-generation drug-eluting stent (DES). Methods : About 352 patients with single de novo coronary stenosis were randomly assigne`d to either clopidogrel group (aspirin plus clopidogrel) or ticagrelor group (aspirin plus ticagrelor) after DES implantation for 1 year ...
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    4. Miniaturized precalibration-based Lissajous scanning fiber probe for high speed endoscopic optical coherence tomography

      Miniaturized precalibration-based Lissajous scanning fiber probe for high speed endoscopic optical coherence tomography
      We present a miniaturized precalibration-based forward-viewing Lissajous scanning fiber probe for high speed endoscopic optical coherence tomography (OCT). The probe is based on an asymmetric fiber cantilever driven by the piezoelectric bender to realize two-dimensional (2D) Lissajous scanning. The stability and repeatability of the Lissajous scanning trajectory of the probe is tested by a position sensitive detector (PSD)-based position calibration setup. The two orthogonal resonant frequencies of the cantilever ...
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    5. Optical coherence tomography evaluation of vertebrobasilar artery stenosis: case series and literature review

      Optical coherence tomography evaluation of vertebrobasilar artery stenosis: case series and literature review
      Background Intracranial vertebrobasilar artery stenosis is an important cause of ischemic stroke. With its high resolution, intravascular optical coherence tomography (OCT) provides detailed assessment of vessel wall features. It is widely applied to identify high-risk plaque in the cardiovascular system, but its use in the intracranial artery has been limited. Objective To explore, in this pilot study, the usefulness of OCT in imaging of the intracranial artery wall. Methods Between ...
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    6. FFOCT imaging based on compressed sensing

      FFOCT imaging based on compressed sensing
      With the demand for high-resolution images, the storage space occupied by the images of the full-field optical coherence tomography (FFOCT) system is becoming more and more intensified. How to reduce the data volume of high-resolution image systems has become a research hotspot in the image processing industry. In particular, precision medicine requires high-resolution images of organs and tissues, and this data storage system requires a large storage space. For this ...
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    7. Cholesterol Crystals are Associated with Carotid Plaque Vulnerability: An Optical Coherence Tomography Study

      Cholesterol Crystals are Associated with Carotid Plaque Vulnerability: An Optical Coherence Tomography Study
      Objective: Vulnerable carotid plaque is associated with cerebrovascular events. Cholesterol crystals are often seen in the atherosclerotic plaques. However, the potential role of cholesterol crystals in carotid plaques destabilization is unknown. We aimed to identify the association between cholesterol crystals and carotid plaque vulnerability. Methods: Optical coherence tomography assessment of carotid plaque was performed in 95 patients. Clinical characteristics and plaque morphology were examined. The differences in plaque characteristics (thrombus ...
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    8. Gabor optical coherence tomographic angiography (GOCTA) (Part II): theoretical basis of sensitivity improvement and optimization for processing speed

      Gabor optical coherence tomographic angiography (GOCTA) (Part II): theoretical basis of sensitivity improvement and optimization for processing speed
      We previously proposed a Gabor optical coherence tomography angiography (GOCTA) algorithm for spectral domain optical coherence tomography (SDOCT) to extract microvascular signals from spectral fringes directly, with speed improvement of 4 to 20 times over existing methods. In this manuscript, we explored the theoretical basis of GOCTA with comparison of experimental data using solid and liquid displacement sample targets, demonstrating that the majority of the GOCTA sensitivity advantage over speckle ...
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    9. Extended focus optical coherence tomography with Fresnel lens

      Extended focus optical coherence tomography with Fresnel lens
      We report a Fresnel lens based spectral domain optical coherence tomography (SDOCT) setup to overcome the trade-off between lateral resolution and focusing depth which is one of the main problems for OCT system. We demonstrated the feasibility of the Fresnel lens based SDOCT system by measuring the lateral resolution at different depth positions and compared these results with that obtained by conventional SDOCT illuminated with a light source of a ...
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    10. Geographic Atrophy Segmentation in SD-OCT Images Using Synthesized Fundus Autofluorescence Imaging

      Geographic Atrophy Segmentation in SD-OCT Images Using Synthesized Fundus Autofluorescence Imaging
      Background and Objective Accurate assessment of geographic atrophy (GA) is critical for diagnosis and therapy of non-exudative age-related macular degeneration (AMD). Herein, we propose a novel GA segmentation framework for spectral-domain optical coherence tomography (SD-OCT) images that employs synthesized fundus autofluorescence (FAF) images. Methods An en-face OCT image is created via the restricted sub-volume projection of three-dimensional OCT data. A GA region-aware conditional generative adversarial network is employed to generate ...
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    11. RETOUCH: The Retinal OCT Fluid Detection and Segmentation Benchmark and Challenge

      RETOUCH: The Retinal OCT Fluid Detection and Segmentation Benchmark and Challenge
      Retinal swelling due to the accumulation of fluid is associated with the most vision-threatening retinal diseases. Optical coherence tomography (OCT) is the current standard of care in assessing the presence and quantity of retinal fluid and image-guided treatment management. Deep learning methods have made their impact across medical imaging, and many retinal OCT analysis methods have been proposed. However, it is currently not clear how successful they are in interpreting ...
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    12. Image contrast correction method in full-field optical coherence tomography

      Image contrast correction method in full-field optical coherence tomography
      An image contrast correction method is proposed for en face images obtained with full-field optical coherence tomography (FFOCT). First, the mechanism of image contrast decrease in FFOCT is considered and the theoretical models of main parameters that degrade image contrast are analyzed. Second, changes of contrast with depth are calculated under various conditions, from which the main parameters that affect contrast in tissue are identified. Then based on the analysis ...
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    13. The Comparison of Morphologic Characteristics of Type 1 and Type 2 Choroidal Neovascularization in Eyes with Neovascular Age-Related Macular Degeneration using Optical Coherence Tomography Angiography

      The Comparison of Morphologic Characteristics of Type 1 and Type 2 Choroidal Neovascularization in Eyes with Neovascular Age-Related Macular Degeneration using Optical Coherence Tomography Angiography
      Purpose: The purpose of this study was to use optical coherence tomography angiography (OCTA) to compare the morphology characteristics of type 1 and 2 choroidal neovascularization (CNV) in neovascular age-related macular degeneration (nAMD) patients. Materials and Methods: This is a retrospective, observational study of 51 eyes with nAMD using OCTA from July 2016 through March 2017. Results: In total, 51 eyes of 50 patients were included in the analysis. According ...
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    14. Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity

      Diagnostic accuracy of intracoronary optical coherence tomography-derived fractional flow reserve for assessment of coronary stenosis severity
      ims: A novel method for computation of fractional flow reserve (FFR) from optical coherence tomography (OCT) was developed recently. This study aimed to evaluate the diagnostic accuracy of a new OCT-based FFR (OFR) computational approach, using wire-based FFR as the reference standard. Methods and results: Patients who underwent both OCT and FFR prior to intervention were analysed. The lumen of the interrogated vessel and the ostia of the side branches ...
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    15. OCT angiography-based monitoring of neovascular regression on fibrovascular membrane after preoperative intravitreal conbercept injection

      OCT angiography-based monitoring of neovascular regression on fibrovascular membrane after preoperative intravitreal conbercept injection
      Purpose To quantify the preoperative neovascular change pattern on the fibrovascular membrane (FVM) within 7 days after intravitreal injection of conbercept (IVC) using optical coherence tomography angiography (OCTA) in proliferative diabetic retinopathy (PDR). Methods Prospective, observational study of PDR patients with visible FVM receiving or not receiving IVC. Neovascular changes were assessed by OCTA pre-IVC and 1, 3, 5, and 7 days post-IVC. Vessel skeleton density (SD) and vessel density ...
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    16. 2D MEMS-based high-speed beam-shifting technique for speckle noise reduction and flow rate measurement in optical coherence tomography

      2D MEMS-based high-speed beam-shifting technique for speckle noise reduction and flow rate measurement in optical coherence tomography
      In this manuscript, a two-dimensional (2D) micro-electro-mechanical system (MEMS)-based, high-speed beam-shifting spectral domain optical coherence tomography (MHB-SDOCT) is proposed for speckle noise reduction and absolute flow rate measurement. By combining a zigzag scanning protocol, the frame rates of 45.2 Hz for speckle reduction and 25.6 Hz for flow rate measurement are achieved for in-vivo tissue imaging. Phantom experimental results have shown that by setting the incident beam ...
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  2. About Nanjing University of Science and Technology

    Nanjing University of Science and Technology

    Nanjing University of Science and Technology (NUST) is one of the national key universities under the guidance of the Ministry of Industry and Information Technology. The university has more than sixty years' experience in providing inspiring and broadened-horizon education. It has become a multi-disciplinary university comprising academic fields including: science, engineering, liberal arts, economics, business, management, law and education. In addition, NUST encompasses a wide array of centers, institutes, programs, and administrative support offices.