1. Nagoya University

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    1. Mentioned In 61 Articles

    2. Automated Detection of Macular Diseases by Optical Coherence Tomography and Artificial Intelligence Machine Learning of Optical Coherence Tomography Images

      Automated Detection of Macular Diseases by Optical Coherence Tomography and Artificial Intelligence Machine Learning of Optical Coherence Tomography Images
      Purpose . Although optical coherence tomography (OCT) is essential for ophthalmologists, reading of findings requires expertise. The purpose of this study is to test deep learning with image augmentation for automated detection of chorioretinal diseases. Methods . A retina specialist diagnosed 1,200 OCT images. The diagnoses involved normal eyes ( ) and those with wet age-related macular degeneration (AMD) ( ), diabetic retinopathy (DR) ( ), epiretinal membranes (ERMs) ( ), and another 19 diseases. Among them, 1,100 ...
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    3. Collateral vessels on optical coherence tomography angiography in eyes with branch retinal vein occlusion

      Collateral vessels on optical coherence tomography angiography in eyes with branch retinal vein occlusion
      Aims To detect collateral vessels using optical coherence tomography angiography (OCTA) in eyes with branch retinal vein occlusion (BRVO) and to investigate the associations with visual outcomes and macular oedema. Methods Eyes with macular oedema secondary to BRVO that underwent OCTA at baseline and were followed up for more than 6 months were enrolled. The presence of collaterals, whether the collaterals were leaky or not, and the associations with visual ...
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    4. Changes in choriocapillaris and retinal morphology after laser photocoagulation by OCT angiography

      Changes in choriocapillaris and retinal morphology after laser photocoagulation by OCT angiography
      Rationale: Earlier studies have shown that laser photocoagulation treatments are associated with good long-term visual acuity in most patients with severe nonproliferative diabetic retinopathy (S-NPDR). Histopathologic studies of autopsied eyes have demonstrated defects in the choriocapillaris beneath the retinal laser lesions secondary to photocoagulation for S-NPDR. These lesions have been observed to expand centrifugally over time especially in the posterior pole, and the atrophy of the retinal pigment epithelium (RPE ...
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    5. CHARACTERISTICS AND CLASSIFICATION OF TYPE 3 NEOVASCULARIZATION WITH B-SCAN FLOW OVERLAY AND EN FACE FLOW IMAGES OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      CHARACTERISTICS AND CLASSIFICATION OF TYPE 3 NEOVASCULARIZATION WITH B-SCAN FLOW OVERLAY AND EN FACE FLOW IMAGES OF OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To study B-scan flow overlay and en face flow optical coherence tomography angiography (OCT-A) images of Type 3 neovascularization (NV) and to characterize a staging system for Type 3 NV based on the OCT-A findings. Methods: We retrospectively collected data on consecutive treatment-naive eyes with Type 3 NV. All eyes underwent fluorescein angiography, indocyanine green angiography, structural spectral domain OCT, and OCT-A (AngioPlex). Localization and extension of abnormal flows ...
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    6. Association of Foveal Avascular Zone Enlargement and Diabetic Retinopathy Progression Using Optical Coherence Tomography Angiography

      Association of Foveal Avascular Zone Enlargement and Diabetic Retinopathy Progression Using Optical Coherence Tomography Angiography
      Purpose: The purpose of this article is to evaluate long-term change of the foveal avascular zone (FAZ) area in diabetic eyes using optical coherence tomography angiography (OCTA) (AngioVue, Avanti OCT, Optovue). Methods: A retrospective chart review was conducted of patients who had undergone OCTA fundus examinations with at least 12 months of follow-up. Eyes with previous laser photocoagulation and antivascular endothelial growth factor treatments were excluded. ImageJ software was used ...
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    7. Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging

      Wavelength Dependence of Ultrahigh-Resolution Optical Coherence Tomography Using Supercontinuum for Biomedical Imaging
      Optical coherence tomography (OCT) is a noninvasive cross-sectional imaging technique with micrometer resolution. The theoretical axial resolution is determined by the center wavelength and bandwidth of the light source, and the wider the bandwidth, the higher the axial resolution. The characteristics of OCT imaging depend on the optical wavelength used. In this paper, we investigated the wavelength dependence of ultrahigh-resolution (UHR) OCT using a supercontinuum for biomedical imaging. Wideband, high-power ...
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    8. Macular displacement after vitrectomy in eyes with idiopathic macular hole determined by optical coherence tomography angiography

      Macular displacement after vitrectomy in eyes with idiopathic macular hole determined by optical coherence tomography angiography
      Purpose To determine whether the macula is displaced after vitrectomy with internal limiting membrane (ILM) peeling in eyes with an idiopathic macular hole. Design A retrospective, observational case series Methods Optical coherence tomography angiography (OCTA) was used to obtain 3 mm 3 mm en face images before and 2, 4, and 8 weeks after the vitrectomy with ILM peeling for 20 eyes of 20 patients with an idiopathic macular hole ...
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    9. Quantification of Macular Microvascular Changes in Patients With Retinitis Pigmentosa Using Optical Coherence Tomography Angiography

      Quantification of Macular Microvascular Changes in Patients With Retinitis Pigmentosa Using Optical Coherence Tomography Angiography
      Purpose : To evaluate the microvascular changes in eyes with RP quantitatively using optical coherence tomography angiography (OCTA) and to determine whether the correlations between these indices and the severity of RP are significant. Methods : This was a retrospective, observational study. The medical records of 53 RP patients and 46 controls were reviewed. The OCTA images were obtained with the Cirrus 5000 with Angioplex, and an automated program was used to ...
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    10. The combination assessment of lipid pool and thrombus by optical coherence tomography can predict the filter no-reflow in primary PCI for ST elevated myocardial infarction

      The combination assessment of lipid pool and thrombus by optical coherence tomography can predict the filter no-reflow in primary PCI for ST elevated myocardial infarction
      The usefulness of distal protection devices is still controversial. Moreover, there is no report on thrombus evaluation by using optical coherence tomography (OCT) for determining whether to use a distal protection device. The aim of the present study was to investigate the predictor of filter no-reflow (FNR) by using OCT in primary percutaneous coronary intervention (PCI) for ST-elevated acute myocardial infarction (STEMI). We performed preinterventional OCT in 25 patients with ...
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    11. OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF THE FOVEAL AVASCULAR ZONE IN CHILDREN WITH A HISTORY OF TREATMENT-REQUIRING RETINOPATHY OF PREMATURITY

      OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF THE FOVEAL AVASCULAR ZONE IN CHILDREN WITH A HISTORY OF TREATMENT-REQUIRING RETINOPATHY OF PREMATURITY
      Purpose: To examine the characteristics of the foveal vascular structure of patients with retinopathy of prematurity (ROP) by optical coherence tomography angiography. Methods: Ten patients with a history of laser photocoagulation or cryopexy treatment for Stage 3 (Zone II) ROP and 10 normal subjects (controls) were included. Foveal avascular zone, vessel density, vessel length, and vascular diameter index were measured by optical coherence tomography angiography using the 3 3-mm Early ...
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    12. Axial resolution and signal-to-noise ratio in deep-tissue imaging with 1.7-μm high-resolution optical coherence tomography with an ultrabroadband laser source

      Axial resolution and signal-to-noise ratio in deep-tissue imaging with 1.7-μm high-resolution optical coherence tomography with an ultrabroadband laser source
      We investigated the axial resolution and signal-to-noise ratio (SNR) characteristics in deep-tissue imaging by 1.7 - m 1.7-m optical coherence tomography (OCT) with the axial resolution of 4.3 m 4.3m in tissue. Because 1.7 - m 1.7-m OCT requires a light source with a spectral width of more than 300 nm full-width at half maximum to achieve such high resolution, the axial resolution in the tissue ...
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    13. Extraction of membrane structure in eyeball from MR volumes

      Extraction of membrane structure in eyeball from MR volumes
      This paper presents an accurate extraction method of spherical shaped membrane structures in the eyeball from MR volumes. In ophthalmic surgery, operation field is limited to a small region. Patient specific surgical simulation is useful to reduce complications. Understanding of tissue structure in the eyeball of a patient is required to achieve patient specific surgical simulations. Previous extraction methods of tissue structure in the eyeball use optical coherence tomography (OCT ...
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    14. Full-range ultrahigh-resolution spectral-domain optical coherence tomography in 1.7 µm wavelength region for deep-penetration and high-resolution imaging of turbid tissues

      Full-range ultrahigh-resolution spectral-domain optical coherence tomography in 1.7 µm wavelength region for deep-penetration and high-resolution imaging of turbid tissues
      For the first time, we developed a full-range ultrahigh-resolution (UHR) spectral-domain optical coherence tomography (SD-OCT) technique working in the 1.7 m wavelength region. This technique allowed high-resolution, deep-tissue imaging. By using a supercontinuum source operating at a wavelength of 1.7 m, an axial resolution of 3.6 m in a tissue specimen was achieved. To enhance the imaging depth of UHR-SD-OCT, we performed full-range OCT imaging based on ...
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    15. Preoperative optical coherence tomography visualization of epiretinal membranes enhances surgical strategies

      Preoperative optical coherence tomography visualization of epiretinal membranes enhances surgical strategies
      Purpose: The aim of this study was to evaluate the usefulness of preoperative optical coherence tomography (OCT) findings in patients with macular epiretinal membrane (ERM) for the planning of surgical strategy. Patients and methods: One hundred twenty-three eyes of 121 patients (49 men, 72 women; mean age, 66 years) with an idiopathic ERM were enrolled. All patients underwent an ophthalmic examination including indirect ophthalmoscopy and OCT (Cirrus HD-OCT 4000 and ...
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  2. About Nagoya University

    Nagoya University

    Nagoya University is a Japanese national university headquartered in Chikusa-ku, Nagoya. It is one of the former 9 imperial universities. Nagoya University began its history in 1871 with its temporary hospital standing on a site where the conference chamber for the former Nagoya clan once stood, and the temporary medical school standing on a site where the magistrate's office for the former Nagoya clan once stood. Thereafter, many transitions took place, and the Aichi Medical College was established in 1920. In 1931, the management of the Aichi Medical College was transferred to the national government and the Nagoya Medical College was newly established in the same year. In 1939, the Nagoya Imperial University was established with the addition of the School of Science and Engineering and the School of Medicine, thus absorbing the Nagoya Medical College.