1. Nagahisa Yoshimura

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    1. Mentioned In 79 Articles

    2. PREVALENCE AND SPATIAL DISTRIBUTION OF CYSTOID SPACES IN RETINITIS PIGMENTOSA: Investigation With Spectral Domain Optical Coherence Tomography

      PREVALENCE AND SPATIAL DISTRIBUTION OF CYSTOID SPACES IN RETINITIS PIGMENTOSA: Investigation With Spectral Domain Optical Coherence Tomography

      Purpose: To investigate the prevalence and spatial distribution of cystoid spaces (CS) in retinitis pigmentosa patients with spectral domain optical coherence tomography. Methods: A total of 529 eyes of 275 patients with retinitis pigmentosa were examined with spectral domain optical coherence tomography. The presence or absence of CS was judged for each eye. Retinal layer and outer retinal status where the CS existed were also investigated. Statistical analysis was performed using 1 eye per 1 patient. Results: Cystoid spaces were present in 119 of 529 eyes (22.5%) of 74 of 275 patients (26.9%). There were no significant differences ...

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    3. Three-dimensional Optical Coherence Tomography Evaluation of Vascular Changes at Arteriovenous Crossings

      Three-dimensional Optical Coherence Tomography Evaluation of Vascular Changes at Arteriovenous Crossings

      Purpose:To study the three-dimensional morphological features of retinal arteriovenous crossings with optical coherence tomography (OCT) and elucidate the vascular changes associated with crossing phenomena as seen on fundus photographs. Methods: We examined 150 consecutive eyes with no ocular disease. In each eye, fundus photographs were taken, and one randomly selected arteriovenous crossing was examined by OCT. The OCT analysis was performed using sequential thin sections along and perpendicular to the retinal vessels. Results:OCT analysis of these arteriovenous crossings showed that the veins abruptly changed their directions to pass the artery and frequently displayed focal luminal narrowing with no ...

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    4. Macular Choroidal Thickness and Volume of Eyes with Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography

      Macular Choroidal Thickness and Volume of Eyes with Reticular Pseudodrusen Using Swept-Source Optical Coherence Tomography

      Purpose To investigate the choroidal thickness/volume of eyes with reticular pseudodrusen using high-penetration swept-source optical coherence tomography (SS-OCT) and to evaluate the choroidal vasculature changes using en face images. Design Prospective cross sectional study. Methods Thirty-eight eyes with reticular pseudodrusen and 14 normal eyes were studied with prototype SS-OCT. Eyes with reticular pseudodrusen were classified into 3 subgroups: eyes without late age-related macular degeneration (AMD) (group1), eyes with neovascular AMD (group2), and eyes with geographic atrophy (group3). Mean regional choroidal thickness/volume measurements were obtained by three-dimensional (3D) raster scanning. The choroidal vascular area was measured using en face ...

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    5. Association between cystoid spaces on indocyanine green hyperfluorescence and optical coherence tomography after vitrectomy for diabetic macular oedema

      Association between cystoid spaces on indocyanine green hyperfluorescence and optical coherence tomography after vitrectomy for diabetic macular oedema

      Purpose To study retrospectively the characteristics of residual indocyanine green (ICG) fluorescence after ICG-assisted vitrectomy and the association with spectral-domain optical coherence tomography (SD-OCT) findings in diabetic macular oedema (DMO). Methods Thirteen consecutive eyes of 12 patients for whom fundus near-infrared fluorescence and 20° retinal sectional images were obtained using HRA2 and Spectralis OCT, respectively, 5 days after vitrectomy combined with ICG-assisted inner limiting membrane peeling for DMO. The relationship between the characteristics of the ICG hyperfluorescence and the cystoid spaces in the outer plexiform layer (OPL) on SD-OCT images was evaluated. Results A total of 390 well-demarcated areas of ...

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    6. Alterations in the Neural and Connective Tissue Components of Glaucomatous Cupping after Glaucoma Surgery using Swept Source Optical Coherence Tomography

      Alterations in the Neural and Connective Tissue Components of Glaucomatous Cupping after Glaucoma Surgery using Swept Source Optical Coherence Tomography

      Purpose: To visualize changes in deep optic nerve head (ONH) structures following glaucoma surgery using (3-dimensional (3D)) swept-source optical coherence tomography (SS-OCT) and to determine the clinical and structural factors associated with postoperative lamina cribrosa (LC) and prelaminar neural tissue (PLT) changes. Methods: In this prospective observational case series, SS-OCT thin-sliced datasets of the ONH covering a 3×3-mm area comprised of 256 B-scans (interval between scans = ∼12µm) were obtained before and 3 months after the surgery and evaluated in 73 eyes of 73 patients with glaucoma. Bruch's membrane opening (BMO) and anterior LC boundary were manually delineated ...

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    7. Measurement of retinal nerve fiber layer thickness in eyes with optic disc swelling by using scanning laser polarimetry and optical coherence tomography

      Measurement of retinal nerve fiber layer thickness in eyes with optic disc swelling by using scanning laser polarimetry and optical coherence tomography
      ...hemic axonal loss. Masayuki Hata, Kazuaki Miyamoto, Akio Oishi, Yugo Kimura, Satoko Nakagawa, Takahiro Horii, Nagahisa Yoshimura Department of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medic...
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    8. Retinal Vessel Tortuosity Associated with Central Retinal Vein Occlusion: An Optical Coherence Tomography Study

      Retinal Vessel Tortuosity Associated with Central Retinal Vein Occlusion: An Optical Coherence Tomography Study

      PURPOSE: To study morphological changes of the retinal vasculature in eyes with central retinal vein occlusion (CRVO) through the use of optical coherence tomography (OCT). METHODS: Major retinal vessels in eyes from 35 consecutive patients (35 eyes) with acute CRVO were prospectively and longitudinally examined with sequential thin sectioning and circumpapillary scanning. Anteroposterior venous tortuosity associated with CRVO was quantified on longitudinal OCT images of a randomly selected major temporal vein. On OCT sections of a given vein, we identified the innermost and the outermost points of the vessel wall. The degree of anteroposterior venous tortuosity was defined as the ...

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    9. Parallelism as a Novel Marker for Structural Integrity of Retinal Layers in Optical Coherence Tomographic Images in Eyes With Epiretinal Membrane

      Parallelism as a Novel Marker for Structural Integrity of Retinal Layers in Optical Coherence Tomographic Images in Eyes With Epiretinal Membrane
      ...ss , * Tomoaki Murakami, * Noriyuki Unoki, * Ken Ogino, * Kazuaki Nishijima, * Shin Yoshitake, * Yoko Dodo, * Nagahisa Yoshimura Accepted 3 September 2013. published online 17 October 2013. Corrected Proof * Abstract *...
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    10. Age- and Hypertension-Dependent Changes in Retinal Vessel Diameter and Wall Thickness: An Optical Coherence Tomography Study

      Age- and Hypertension-Dependent Changes in Retinal Vessel Diameter and Wall Thickness: An Optical Coherence Tomography Study
      ...partment of Ophthalmology and Visual Sciences, Kyoto University Graduate School of Medicine, Kyoto, Japan , * Nagahisa Yoshimura Affiliations + Department of Ophthalmology and Visual Sciences, Kyoto University Graduate S...
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    11. Three-Dimensional Imaging of Lamina Cribrosa Defects in Glaucoma Using Swept-Source Optical Coherence Tomography

      Three-Dimensional Imaging of Lamina Cribrosa Defects in Glaucoma Using Swept-Source Optical Coherence Tomography

      Purpose. To visualize lamina cribrosa defects using three-dimensional (3D) swept-source optical coherence tomography (SS-OCT), and to determine the factors associated with this feature. Methods. All subjects were examined using an SS-OCT prototype system, which uses a tunable laser as a light source, operated at 100,000 Hz A-scan repetition rate in the 1050-nm wavelength. A 3D raster scan protocol consisting of 256 × 256 A-scans was acquired over a square area of 3 mm × 3 mm centered on the optic disc. En face sectioned volume and serial en face images and orthogonal (horizontal and vertical) serial B-scans were evaluated. Results. A ...

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    12. Three Dimensional Imaging of the Lamina Cribrosa Defects in Glaucoma Using Swept-source Optical Coherence Tomography

      Three Dimensional Imaging of the Lamina Cribrosa Defects in Glaucoma Using Swept-source Optical Coherence Tomography

      Purpose: To visualize and analyze focal lamina cribrosa defects using 3-dimensional (3D) swept-source optical coherence tomography (SS-OCT). Methods: All the subjects were examined using an SS-OCT prototype system, which employs a tunable laser as a light source operated at 100,000 Hz A-scan repetition rate in the 1,050 nm wavelength. Three-dimensional raster scan protocol comprising 256 × 256 A-scans was acquired over a square area of 3 mm × 3 mm centered at the optic disc. En face sectioned volume and serial en face images, which were reconstructed from the 3D data set, and orthogonal (horizontal and vertical) serial B-scan were ...

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    13. Circle and Grid-wise Analyses of Peripapillary Nerve Fiber Layers by Spectral Domain Optical Coherence Tomography in Early Stage Glaucoma

      Circle and Grid-wise Analyses of Peripapillary Nerve Fiber Layers by Spectral Domain Optical Coherence Tomography in Early Stage Glaucoma

      PURPOSE. To study diagnostic performances of circle and grid-wise analyses of peripapillary retinal nerve fiber layer thickness (RNFLT) using spectral domain optical coherence tomography (SD-OCT) in early stage glaucoma. METHODS. Eighty-nine open-angle glaucoma (OAG) eyes (mean deviation, -2.5 ± 1.8 dB) and 89 age-matched normal eyes were studied. Peripapillary RNFLT was analyzed using SD-OCT raster scan in a 6.0 × 6.0 mm area. Averaged RNFLT was calculated over 0.1 × 0.1, 0.21 × 0.21, or 0.42 × 0.42 mm grids in the peripapillary area (grid method), or arcuate sector areas between 2.8 and 4 ...

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    14. High-Penetration Optical Coherence Tomography and Enhanced Depth Imaging in Presumed Retinal Pigment Epithelial Hamartoma

      High-Penetration Optical Coherence Tomography and Enhanced Depth Imaging in Presumed Retinal Pigment Epithelial Hamartoma

      Purpose: To report on high-penetrating swept source optical coherence tomography (SS-OCT) imaging and enhanced depth imaging in an eye with presumed retinal pigment epithelial hamartoma . Methods and Patients: A 60-year-old man with presumed retinal pigment epithelial hamartoma underwent complete ophthalmologic examination, including fluorescein angiography, indocyanine green angiography, enhanced depth imaging OCT, and SS-OCT. Results: In the left eye, there were six darkly pigmented, nodular, circumscribed lesions in the macular area. The margins were well defined and were not associated with changes such as edema, exudation, or hemorrhage. Fluorescein angiography revealed a minimally dilated feeding artery and draining vein in each ...

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    15. 1-15 of 79 1 2 3 4 5 6 »
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  2. About Nagahisa Yoshimura

    Nagahisa Yoshimura

    Nagahisa Yoshimura, MD, is with Department of Ophthalmology, Shinshu University School of Medicine, Matsumoto, Japan.