1. Mircea Mujat

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    1. Mentioned In 29 Articles

    2. Combined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue

      Combined reflectance confocal microscopy-optical coherence tomography system for imaging of biological tissue
      A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at ...
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    3. Physical Sciences ReceivesNIH Grant for Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes

      Physical Sciences ReceivesNIH Grant  for Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes
      ...Measurement of Retinal Nerves and Blood Vessels as Markers for Type 1 Diabetes. The principal investigator is Mircea Mujat. The program began in 2017 and ends in 2018. Below is a summary of the proposed work.

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    4. Combined Reflectance Confocal Microscopy-Optical Coherence Tomography System for Imaging of Biological Tissue

      Combined Reflectance Confocal Microscopy-Optical Coherence Tomography System for Imaging of Biological Tissue
      A dual-modality apparatus for imaging of biological tissue includes a reflectance confocal microscopy (RCM) imaging apparatus and an optical coherence tomography (OCT) imaging apparatus. A first optical component reflects a first beam of light provided by a RCM imaging apparatus towards a sample and passes a second beam of light provided by an OCT imaging apparatus towards the sample, such that the first and second beam of lights share at ...
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    5. Physical Sciences Receives NIH Grant for Optical Coherence Tomography Based on Freeze Drying Microscopy

      Physical Sciences Receives NIH Grant for Optical Coherence Tomography Based on Freeze Drying Microscopy
      ...or $538,335 for Optical Coherence Tomography Based on Freeze Drying Microscopy. The principal investigator is Mircea Mujat. The program began in 2009 and ends in 2015. Below is a summary of the proposed work. Physical S...
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    6. Physical Sciences Incorporated Receives NIH Grant for Optical Coherence Tomography Based Freeze Drying Microscopy

      Physical Sciences Incorporated Receives NIH Grant for Optical Coherence Tomography Based Freeze Drying Microscopy
      ... for $569,045 for Optical Coherence Tomography Based Freeze Drying Microscopy.  The principal investigator is Mircea Mujat. The program started in 2009 and lends in 2015. A summary of the program is given below. Physica...
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    7. Accurate prediction of collapse temperature using optical coherence tomography-based freeze-drying microscopy

      Accurate prediction of collapse temperature using optical coherence tomography-based freeze-drying microscopy
      The objective of this study was to assess the feasibility of developing and applying a laboratory tool that can provide three-dimensional product structural information during freeze-drying and which can accurately characterize the collapse temperature ( T c ) of pharmaceutical formulations designed for freeze-drying. A single-vial freeze dryer coupled with optical coherence tomography freeze-drying microscopy (OCTFDM) was developed to investigate the structure and T c of formulations in pharmaceutically relevant products containers ...
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    8. Combined reflectance confocal microscopy/optical coherence tomography imaging for skin burn assessment

      Combined reflectance confocal microscopy/optical coherence tomography imaging for skin burn assessment
      A combined high-resolution reflectance confocal microscopy (RCM)/optical coherence tomography (OCT) instrument for assessing skin burn gravity has been built and tested. This instruments allows for visualizing skin intracellular details with submicron resolution in the RCM mode and morphological and birefringence modifications to depths on the order of 1.2 mm in the OCT mode. Preliminary testing of the dual modality imaging approach has been performed on the skin of ...
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    9. Optical Coherence Tomography (OCT) Freeze Drying Microscopy

      Optical Coherence Tomography (OCT) Freeze Drying Microscopy
      A product critical temperature during freeze drying is determined. The product is imaged using optical coherence tomography ("OCT"). The product is freeze dried while the temperature of the product is measured. The product critical temperature is the temperature at which a product structure event occurs during freeze drying.
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    10. Adaptive optics line scanning ophthalmoscope

      Adaptive optics line scanning ophthalmoscope
      A first optical module scans a portion of an eye with a line of light, descans reflected light from the scanned portion of the eye and confocally provides output light in a line focus configuration. A detection device detects the output light and images the portion of the eye. A second optical module detects an optical distortion and corrects the optical distortion in the line of light scanned on the ...
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    11. Optical coherence tomography-based freeze-drying microscopy

      Optical coherence tomography-based freeze-drying microscopy
      A new type of freeze-drying microscope based upon time-domain optical coherence tomography is presented here (OCT-FDM). The microscope allows for real-time, in situ 3D imaging of pharmaceutical formulations in vials relevant for manufacturing processes with a lateral resolution of 7 m and an axial resolution of 5 m. Correlation of volumetric structural imaging with product temperature measured during the freeze-drying cycle allowed investigation of structural changes in the product and ...
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  2. About Mircea Mujat

    Mircea Mujat

    Mircea Mujat is a Principal Research Scientist at Physical Sciences Inc.