1. University of Miami

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    1. Mentioned In 456 Articles

    2. Quantifying lipofuscin in retinal pigment epithelium in vivo by visible-light optical coherence tomography-based multimodal imaging

      Quantifying lipofuscin in retinal pigment epithelium in vivo by visible-light optical coherence tomography-based multimodal imaging
      Lipofuscin in the retinal pigment epithelium (RPE) is the major source of fundus autofluorescence (FAF). A technical challenge to accurately quantify the FAF intensities, thus the lipofuscin concentration, is to compensate the light attenuation of RPE melanin. We developed the VIS-OCT-FAF technology to accomplish optical coherence tomography (OCT) and FAF simultaneously with a single broadband visible light source. We demonstrated that light attenuation by RPE melanin can be assessed and ...
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    3. SPATIAL DISTRIBUTION OF CHORIOCAPILLARIS IMPAIRMENT IN EYES WITH CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Quantitative OCT Angiography Study

      SPATIAL DISTRIBUTION OF CHORIOCAPILLARIS IMPAIRMENT IN EYES WITH CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Quantitative OCT Angiography Study
      ...Institute of Technology, Cambridge, Massachusetts; §Department of Ophthalmology, Bascom Palmer Eye Institute, University of Miami Miller School of Medicine, Miami, Florida. Reprint requests: James G. Fujimoto, PhD, Depar...
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    4. University of Miami Receives NIH Grant for Endothelium/Descemet's Membrane Complex Optical Tomography

      University of Miami Receives NIH Grant for Endothelium/Descemet's Membrane Complex Optical Tomography
      ...d accurately diagnose graft rejection. This project is led by Mohamed Abou Shousha, M.D., FRCS, Ph.D., of the Bascom Palmer Eye Institute (BPEI). He is a highly trained cornea specialist with broad experience in corneal ...
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    5. Estimating Visual Field Mean Deviation using Optical Coherence Tomographic Nerve Fiber Layer Measurements in Glaucoma Patients

      Estimating Visual Field Mean Deviation using Optical Coherence Tomographic Nerve Fiber Layer Measurements in Glaucoma Patients
      To construct an optical coherence tomography (OCT) nerve fiber layer (NFL) parameter that has maximal correlation and agreement with visual field (VF) mean deviation (MD). The NFL_MD parameter in dB scale was calculated from the peripapillary NFL thickness profile nonlinear transformation and VF area-weighted averaging. From the Advanced Imaging for Glaucoma study, 245 normal, 420 pre-perimetric glaucoma (PPG), and 289 perimetric glaucoma (PG) eyes were selected. NFL_MD had significantly higher ...
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    6. The Bruno Lumbroso Lecture at the 7th International Congress on OCT Angiography

      The Bruno Lumbroso Lecture at the 7th International Congress on OCT Angiography
      Dear Colleagues: As you know, the International Congress on OCT Angiography, En Face OCT and Advances in OCT that Professor Bruno Lumbroso initiated few years ago will be in its 7th Year this December 2019 in Rome. Certainly, this global Congress has become one of the most successful, most-attended, and most educational meetings in the field of retinal imaging. Every December during the past six years, more than 1,000 ...
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    7. Correlations between Different Choriocapillaris Flow Deficit Parameters in Normal Eyes using Swept Source OCT Angiography

      Correlations between Different Choriocapillaris Flow Deficit Parameters in Normal Eyes using Swept Source OCT Angiography
      Purpose Choriocapillaris (CC) imaging of normal eyes with swept-source optical coherence tomography SS-OCTA was performed, and the percentage of CC flow deficits (FD%) and the average area of CC flow deficits (FDa) were compared within given macular regions. Design A prospective, cross-sectional study. Methods Subjects with normal eyes ranging in age from their 20s through their 80s were imaged with SS-OCTA (PLEX Elite 9000, Carl Zeiss Meditec, Dublin, CA) using ...
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    8. Are Dilated Fundus Exams Needed for Optical Coherence Tomography–Guided Re-treatment of Exudative Age-Related Macular Degeneration?

      Are Dilated Fundus Exams Needed for Optical Coherence Tomography–Guided Re-treatment of Exudative Age-Related Macular Degeneration?
      Purpose To determine whether presence of macular hemorrhage on dilated fundus exam (DFE) or fundus photography influences vision outcomes with optical coherence tomography (OCT)-guided pro re nata (PRN) ranibizumab (RBZ) re-treatment in patients with neovascular age-related macular degeneration (nAMD), we investigated whether hemorrhage without OCT-detectable fluid impacted vision outcomes. Design Post hoc analysis of prospectively collected data from the 24-month phase III HARBOR trial (NCT00891735). Participants This post hoc ...
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    9. Optical Coherence Tomography as a Predictor of Visual Outcomes after Phacoemulsification in Eyes with Preexisting Epiretinal Membranes

      Optical Coherence Tomography as a Predictor of Visual Outcomes after Phacoemulsification in Eyes with Preexisting Epiretinal Membranes
      Purpose: To elucidate optical coherence tomography features that may be predictive of visual outcomes after phacoemulsification in eyes with a primary and secondary Epiretinal Membrane (ERM). Patients and methods: Retrospective consecutive case series. Visual Acuity (VA) and Spectral-Domain Optical Coherence Tomography (SD-OCT) characteristics at pre-operative and post-operative visits in eyes with pre- existing ERM that underwent uncomplicated phacoemulsification were analyzed. Results: In the 57 eyes, median VA improved significantly from ...
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    10. Two-Year Risk of Exudation in Eyes with Nonexudative Age-Related Macular Degeneration and Subclinical Neovascularization Detected with Swept Source Optical Coherence Tomography Angiography

      Two-Year Risk of Exudation in Eyes with Nonexudative Age-Related Macular Degeneration and Subclinical Neovascularization Detected with Swept Source Optical Coherence Tomography Angiography
      Purpose Swept source optical coherence tomography angiography (SS-OCTA) was used to study the prevalence, incidence, and natural history of subclinical macular neovascularization (MNV) in eyes with unilateral nonexudative age-related macular degeneration. Design Prospective cohort study. Methods Patients were imaged using 3- 3-mm and 6- 6-mm SS-OCTA scan patterns. MNV was detected using the outer retina to choriocapillaris en face slab. Prevalence and incidence of subclinical MNV, KaplanMeier cumulative estimates for ...
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    11. Widefield Swept-Source Optical Coherence Tomography Angiography of Proliferative Diabetic Retinopathy

      Widefield Swept-Source Optical Coherence Tomography Angiography of Proliferative Diabetic Retinopathy
      BACKGROUND AND OBJECTIVE: To demonstrate the utility of widefield swept-source optical coherence tomography angiography (SS-OCTA) for the diagnosis and management of proliferative diabetic retinopathy (PDR). PATIENTS AND METHODS: Consecutive patients with vision-threatening diabetic retinopathy were imaged with widefield SS-OCTA using the 12 mm 12 mm scan pattern. RESULTS: Twenty-four eyes of 12 patients underwent SS-OCTA imaging. In all 24 eyes, the en face total retinal flow images detected areas of ...
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    12. Computational Methods to Quantify Human Lens Shape and Optical Properties Using Laser Ray Tracing and Optical Coherence Tomography (Thesis)

      Computational Methods to Quantify Human Lens Shape and Optical Properties Using Laser Ray Tracing and Optical Coherence Tomography (Thesis)
      Vision is worsening on a global scale. Myopia, a visual condition where distant objects appear blurry, is increasing in prevalence at an alarming rate. This condition typically starts during childhood and progressively worsens, potentially leading to more severe visual conditions if left unchecked. Currently, the best treatment method to slow myopic progression is heavily debated as the etiology of myopia is not fully understood. The development of effective long-term solutions ...
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    13. Widefield optical coherence tomography of foveal dragging in retinopathy of prematurity

      Widefield optical coherence tomography of foveal dragging in retinopathy of prematurity
      Dear Editor, Despite substantial advances in neonatal medicine, retinopathy of prematurity (ROP) continues to be a serious therapeutic challenge[1]. Visual acuity loss in patients with ROP has been associated with structural retinal abnormalities (including retinal detachment, retinal folds, and pigmentary retinopathy), cataract, glaucoma, and amblyopia due to refractive error or strabismus[2]. A subset of patients with ROP, either treated or untreated may develop temporal dragging of the fovea ...
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    14. Lessons Learned From Avastin and OCT–The Great, the Good, the Bad, and the Ugly

      Lessons Learned From Avastin and OCT–The Great, the Good, the Bad, and the Ugly
      Purpose: To describe the synergistic benefits and cost savings from the use of optical coherence tomography (OCT) and vascular endothelial growth factor (VEGF) inhibitors, particularly intravitreal bevacizumab, in the treatment of exudative age-related macular degeneration (AMD). Design: Retrospective literature review and personal perspective. Methods: Retrospective literature review and personal perspective. Results: The introduction of the first clinically useful OCT instrument coincided with early-phase clinical trials of a drug that would ...
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  2. About University of Miami

    University of Miami

    University of Miami has more than 15,400 undergraduate and graduate students from around the world that call UM home during the academic semesters. The Leonard M. Miller School of Medicine is the school of medical education at the University of Miami and serves as its major teaching facility, and is one of the largest hospitals in the United States, having more than 1550 beds. Bascom Palmer Eye Institute  is committed to the protection and preservation of the treasured gift of sight. The Institute's full-time faculty of internationally-respected physicians and scientists are skilled in every ophthalmic subspecialty. Bascom Palmer Eye Institute, which serves as the Department of Ophthalmology for the University of Miami Miller School of Medicine in Miami, Florida, is recognized as one of the world's finest and most progressive centers for ophthalmic care, research and education.