1. Mikael Timo Erkkilä

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    1. Mentioned In 6 Articles

    2. Feature Of The Week 03/31/2019: Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue

      Feature Of The Week 03/31/2019: Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue
      We have developed a multimodal laser scanning microscope (LSM) platform combining optical coherence tomography (OCT), spectral focusing coherent anti-Stokes Raman scattering (SF-CARS), second harmonic generation (SHG) and two-photon excited fluorescence (TPF). Morphological, molecular and biochemical information from tissues can be collected in a non-invasive and label-free manner by merging ultra-fast Ti:sapphire lasers with well-developed optical imaging techniques. The combination of the proposed imaging modalities enables increased sensitivity and specificity ...
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    3. Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue

      Depth resolved label-free multimodal optical imaging platform to study morpho-molecular composition of tissue
      Multimodal imaging platforms offer a vast array of tissue information in a single image acquisition by combining complementary imaging techniques. By merging different systems, better tissue characterization can be achieved than is possible by the constituent imaging modalities alone. The combination of optical coherence tomography (OCT) with non-linear optical imaging (NLOI) techniques such as two-photon excited fluorescence (TPEF), second harmonic generation (SHG) and coherent anti-Stokes Raman scattering (CARS) provides access ...
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    4. Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane

      Endoscopic optical coherence tomography with wide field-of-view for the morphological and functional assessment of the human tympanic membrane
      An endoscopic optical coherence tomography (OCT) system with a wide field-of-view of 8 mm is presented, which combines the image capability of endoscopic imaging at the middle ear with the advantages of functional OCT imaging, allowing a morphological and functional assessment of the human tympanic membrane. The endoscopic tube has a diameter of 3.5 mm and contains gradient-index optics for simultaneous forward-viewing OCT and video endoscopy. The endoscope allows ...
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    5. Combination of High-Resolution Optical Coherence Tomography and Raman Spectroscopy for Improved Staging and Grading in Bladder Cancer

      Combination of High-Resolution Optical Coherence Tomography and Raman Spectroscopy for Improved Staging and Grading in Bladder Cancer
      We present a combination of optical coherence tomography (OCT) and Raman spectroscopy (RS) for improved diagnosis and discrimination of different stages and grades of bladder cancer ex vivo by linking the complementary information provided by these two techniques. Bladder samples were obtained from biopsies dissected via transurethral resection of the bladder tumor (TURBT). As OCT provides structural information rapidly, it was used as a red-flag technology to scan the bladder ...
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    6. A System for Clinical Use of Endoscopic Optical Coherence Tomography

      A System for Clinical Use of Endoscopic Optical Coherence Tomography
      Introduction: Optical Coherence Tomography (OCT) allows non-invasive high-resolution imaging of tissues. With a penetration depth of a few millimeters it's possible to image the tympanic membrane and the close-by part of the tympanum, e.g. for diagnostics of otitis media and middle ear effusion. In the field of in vivo examination there are difficulties in access to the human tympanic membrane due to the narrow and curved external ear ...
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    7. Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear

      Doppler optical coherence tomography as a promising tool for detecting fluid in the human middle ear
      The treatment of otitis media requires classifying the effusion in the tympanic cavity for choosing appropriate therapeutic strategies. Otoscopic examination of the middle ear depends on the expertise of the physician and is often hampered in case of inflammatory alterations of the tympanic membrane. In otologic research, optical coherence tomography is an innovative non-invasive imaging technique utilized for visualizing the tympanic membrane. This ex vivo study presents the possibility of ...
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  2. About Mikael Timo Erkkilä

    Mikael Timo Erkkilä

    Mikael Timo Erkkilä received his B-Sc. in Physics from the Friedrich Schiller University Jena, Germany in 2013 and his M.Sc. form the Technical University and Universitätsklinikum Dresden, Gemany, in 2016. Since 2016 he works at the Center for Medical Physics and Biomedical Engineering at the Medical University of Vienna as PhD student where is research is focused on the translation of OCT and FLIM into the surgical environment.