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    1. Mentioned In 67 Articles

    2. Ability of Swept-source OCT and OCT-angiography to detect neuroretinal and vasculature changes in patients with Parkinson disease and essential tremor

      Ability of Swept-source OCT and OCT-angiography to detect neuroretinal and vasculature changes in patients with Parkinson disease and essential tremor
      Background/Objectives To evaluate the ability of swept-source optical coherence tomography (SS-OCT) implemented with angiography analysis (SS-OCTA) to detect neuro-retinal and vasculature changes in patients with Parkinsons disease (PD) and essential tremor (ET), and to distinguish between both pathologies. Subjects/Methods A total 42 PD and 26 ET patients and 146 controls underwent retinal evaluation using SS-OCT plus OCT-Angio. The macular (m) and peripapillary (p) retinal nerve fiber layer (RNFL ...
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    3. Comparison of Machine Learning Methods Using Spectralis OCT for Diagnosis and Disability Progression Prognosis in Multiple Sclerosis

      Comparison of Machine Learning Methods Using Spectralis OCT for Diagnosis and Disability Progression Prognosis in Multiple Sclerosis
      Machine learning approaches in diagnosis and prognosis of multiple sclerosis (MS) were analysed using retinal nerve fiber layer (RNFL) thickness, measured by optical coherence tomography (OCT). A cross-sectional study (72 MS patients and 30 healthy controls) was used for diagnosis. These 72 MS patients were involved in a 10-year longitudinal follow-up study for prognostic purposes. Structural measurements of RNFL thickness were performed using different Spectralis OCT protocols: fast macular thickness ...
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    4. Retinal Vascularization Abnormalities Studied by Optical Coherence Tomography Angiography (OCTA) in Type 2 Diabetic Patients with Moderate Diabetic Retinopathy

      Retinal Vascularization Abnormalities Studied by Optical Coherence Tomography Angiography (OCTA) in Type 2 Diabetic Patients with Moderate Diabetic Retinopathy
      Diabetic retinopathy (DR) is the most severe and frequent retinal vascular disease that causes significant visual loss on a global scale. The purpose of our study was to evaluate retinal vascularization in the superficial capillary plexus (SCP), the deep capillary plexus (DCP) and the choriocapillaris (CC) and changes in the foveal avascular zone (FAZ) by optical tomography angiography (OCTA) in patients with type 2 diabetes mellitus (DM2) with moderate DR ...
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    5. Retina analysis with optical coherence tomography in patients with fibromyalgia

      Retina analysis with optical coherence tomography in patients with fibromyalgia
      Purpose To evaluate the inner layers of the retina in patients with fibromyalgia (FM) compared to healthy subjects using a posterior pole protocol analysis in optical coherence tomography (OCT) and the relationship of structural measures with quality of life. Methods Seventy-four eyes of healthy subjects and 55 eyes of FM patients were analyzed. FM group was divided into three subgroups depending on the phenotype of the disease (group 1, biologic ...
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    6. Automatic Diagnosis of Bipolar Disorder Using Optical Coherence Tomography Data and Artificial Intelligence

      Automatic Diagnosis of Bipolar Disorder Using Optical Coherence Tomography Data and Artificial Intelligence
      Background: The aim of this study is to explore an objective approach that aids the diagnosis of bipolar disorder (BD), based on optical coherence tomography (OCT) data which are analyzed using artificial intelligence. Methods: Structural analyses of nine layers of the retina were analyzed in 17 type I BD patients and 42 controls, according to the areas defined by the Early Treatment Diabetic Retinopathy Study (ETDRS) chart. The most discriminating ...
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    7. Changes in retinal layers in type 1 diabetes mellitus without retinopathy measured by spectral domain and swept source OCTs

      Changes in retinal layers in type 1 diabetes mellitus without retinopathy measured by spectral domain and swept source OCTs
      To evaluate changes in inner retinal layer (IRL) thicknesses in patients with type 1 diabetes mellitus (DM1) with no diabetic retinopathy (DR) using two different optical coherence tomography (OCT) devices. Ninety DM1 and 60 healthy eyes were evaluated using spectral domain (SD)-OCT and swept source (SS)-OCT to measure changes in the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL) and inner nuclear layer ...
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    8. Machine learning in diagnosis and disability prediction of multiple sclerosis using optical coherence tomography

      Machine learning in diagnosis and disability prediction of multiple sclerosis using optical coherence tomography
      Background Multiple sclerosis (MS) is a neurodegenerative disease that affects the central nervous system, especially the brain, spinal cord, and optic nerve. Diagnosis of this disease is a very complex process and generally requires a lot of time. In addition, treatments are applied without any information on the disability course in each MS patient. For these two reasons, the objective of this study was to improve the MS diagnosis and ...
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    9. Microperimetry and Optical Coherence Tomography Changes in Type-1 Diabetes Mellitus without Retinopathy

      Microperimetry and Optical Coherence Tomography Changes in Type-1 Diabetes Mellitus without Retinopathy
      Background: We aimed to measure and correlate inner retinal layer (IRL) thickness and macular sensitivity by optical coherence tomography (OCT) and by microperimetry, respectively, in type 1 diabetes mellitus patients (DM1) without diabetic retinopathy (DR). Methods: Fifty-one DM1 patients and 81 age-matched healthy subjects underwent measurement of the axial length (AL), retinal thickness in the macular ETDRS areas by swept source (SS)-OCT and macular sensitivity by microperimeter. Results: The ...
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    10. Angiography with optical coherence tomography as a biomarker in multiple sclerosis

      Angiography with optical coherence tomography as a biomarker in multiple sclerosis
      Purpose To investigate superficial retinal microvascular plexuses detected by optical coherence tomography angiography (OCT-A) in multiple sclerosis (MS) subjects and compare them with healthy controls. Methods A total of 92 eyes from 92 patients with relapsing-remitting MS and 149 control eyes were included in this prospective observational study. OCT-A imaging was performed using Triton Swept-Source OCT (Topcon Corporation, Japan). The vessel density (VD) percentage in the superficial retinal plexus and ...
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    11. Early diagnosis of multiple sclerosis by OCT analysis using Cohen's d method and a neural network as classifier

      Early diagnosis of multiple sclerosis by OCT analysis using Cohen's d method and a neural network as classifier
      Background The consequences of inflammation, demyelination, axonal degeneration and neuronal loss in the central nervous system, typical of the development of multiple sclerosis (MS), are manifested in thinning of the retina and optic nerve. The purpose of this work is to diagnose early-stage MS patients based on analysis of retinal layer thickness obtained by swept-source optical coherence tomography (SS-OCT). Method OCT (Triton SS-OCT device -Topcon, Tokyo, Japan-) recordings were obtained ...
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    12. Use of the new MultiColour SPECTRALIS® software for identifying retinal nerve fibre layer defects

      Use of the new MultiColour SPECTRALIS® software for identifying retinal nerve fibre layer defects
      The classical fibre photography traditionally used to identify defects in the retinal nerve fibre layer (RNFL), has been partially discontinued due to poor availability. The new MultiColour module of SPECTRALIS Optical Coherence Tomography (OCT), using three different laser wavelengths simultaneously, can provide images that identify the structures of the retina in different colours according to their depth. A small concordance study was conducted to determine the usefulness of the new ...
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    13. Relationship between vascular densities of choriocapillaris and the whole choroid using OCTA

      Relationship between vascular densities of choriocapillaris and the whole choroid using OCTA
      Purpose To study the vascular density (VD) of choriocapillaris and the whole choroid using optical coherence tomography-angiography (OCTA). Methods Cross-sectional study enrolling healthy individuals between 18 and 35 years old and with an axial length (AL) lower than 26 mm, who were examined with swept-source OCTA Triton DRI (Topcon). Color pictures of both VD were obtained from a fovea-centered 66 mm macular exam, which were divided into 900 squares and ...
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    14. Diagnostic capability of a linear discriminant function applied to a novel Spectralis OCT glaucoma-detection protocol

      Diagnostic capability of a linear discriminant function applied to a novel Spectralis OCT glaucoma-detection protocol
      Background Bruch membrane openingminimum rim width (BMOMRW) assessment offers a new diagnostic use in glaucoma patients of the Glaucoma Module Premium Edition (GMPE) available for the Spectralis optical coherence tomography (OCT) system. The objective of our research was to evaluate the diagnostic benefits of examining BMOMRW and peripapillary retinal nerve fibre layer (pRNFL) readings acquired with Spectralis OCT to distinguish between healthy and mild glaucoma patients, comparing those readings with ...
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    15. Reproducibility of retinal and choroidal measurements using swept-source optical coherence tomography in patients with Parkinson’s disease

      Reproducibility of retinal and choroidal measurements using swept-source optical coherence tomography in patients with Parkinson’s disease
      Purpose: To assess the reproducibility of retinal and choroidal measurements in the macular and peripapillary areas using swept-source optical coherence tomography in patients with Parkinsons disease. Methods: A total of 63 eyes of 63 patients with idiopathic Parkinsons disease were evaluated using a three-dimensional protocol of swept-source optical coherence tomography. The following layers were analyzed: full retinal thickness, retinal nerve fiber layer, ganglion cell layer, and choroid. The coefficient of ...
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    16. Ability of Swept-Source Optical Coherence Tomography to Detect Retinal and Choroidal Changes in Patients with Multiple Sclerosis

      Ability of Swept-Source Optical Coherence Tomography to Detect Retinal and Choroidal Changes in Patients with Multiple Sclerosis
      Purpose . To evaluate the ability of new swept-source (SS) optical coherence tomography (OCT) technology to detect changes in retinal and choroidal thickness in patients with multiple sclerosis (MS). Methods . A total of 101 healthy and 97 MS eyes underwent retinal and choroidal assessment using SS Triton OCT (Topcon). Macular thickness and peripapillary data (retinal, ganglion cell layer (GCL+, GCL++) and retinal nerve fiber layer (RNFL) thickness) were analyzed, including choroidal ...
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  2. About Miguel Servet University Hospital

    Miguel Servet University Hospital

    Miguel Servet University Hospital