1. Michel Pâques

    0 Comments Leave a Comment

    1-15 of 15
    1. Mentioned In 15 Articles

    2. Cell Motility as Contrast Agent in Retinal Explant Imaging With Full-Field Optical Coherence Tomography

      Cell Motility as Contrast Agent in Retinal Explant Imaging With Full-Field Optical Coherence Tomography
      Purpose : To use cell motility as a contrast agent in retinal explants. Methods : Macaque and mouse retinal explants were imaged with high resolution full field optical coherence tomography (FFOCT) and dynamic FFOCT, coupled with fluorescence imaging. Results : Static and dynamic FFOCT create complementary contrast from different structures within a cell. When imaging in vitro samples, static FFOCT detects steep refractive index gradients to reveal stationary structures including fibers, vessels, collagen ...
      Read Full Article
    3. Appearance of the Retina With Full-Field Optical Coherence Tomography

      Appearance of the Retina With Full-Field Optical Coherence Tomography
      Purpose : To interpret full-field optical coherence tomography (FFOCT) images of ex vivo retina. Methods : Flatmounted retinas of human, primate, pig, sheep, rat, and mouse were imaged using FFOCT. To identify retinal ganglion and amacrine cells, fixed samples immunolabeled against Tuj1 and Brn3a or live samples labeled in vitro with green fluorescent protein (GFP) were analyzed by combining FFOCT, fluorescence confocal microscopy (FCM), and fluorescence-FFOCT. To investigate postmortem tissue changes, time ...
      Read Full Article
    4. NEW INSIGHT INTO THE MACULAR DEEP VASCULAR PLEXUS IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.

      NEW INSIGHT INTO THE MACULAR DEEP VASCULAR PLEXUS IMAGED BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY.
      Purpose: To describe the macular deep capillary plexus (DCP) in normal eyes using optical coherence tomography angiography. Methods: Retrospective study including 41 consecutive normal eyes imaged using optical coherence tomography angiography (RTVue XR Avanti; Optovue Inc). Default autosegmentation of the superficial capillary plexus (SCP) and DCP, and manual adjustments of "deep settings" were used to analyze the organization of the normal macular microvascularization and to investigate in vivo the connection ...
      Read Full Article
    5. Functional and high-resolution retinal imaging monitoring photoreceptor damage in acute macular neuroretinopathy

      Functional and high-resolution retinal imaging monitoring photoreceptor damage in acute macular neuroretinopathy
      Background To report functional and high-resolution retinal imaging abnormalities, including adaptive optics (AO) throughout the course of acute macular neuroretinopathy (AMNR). Methods Two female patients (four eyes) with a diagnosis of AMNR were observed at the Clinical Investigation Center, CHNO des Quinze-Vingts, Paris, France. The patients underwent detailed ophthalmic examination including best-corrected visual acuity, slit-lamp examination, kinetic and static perimetry, full-field and multifocal electroretinogram, infrared reflectance, autofluorescence imaging and spectral-domain ...
      Read Full Article
      Mentions: Michel Pâques
    6. Full-Field Optical Coherence Tomography of Human Donor and Pathological Corneas

      Full-Field Optical Coherence Tomography of Human Donor and Pathological Corneas
      Purpose : To evaluate the performance of a full-field optical coherence tomography (FF-OCT) system in the study of human donor and pathological corneas and assess its suitability for use in eye banks. Methods : Our study was carried out using an FF-OCT system developed for non-invasive imaging of tissue structures in depth with ultrahigh resolution (1m in all directions). Images were acquired from eight stored human donor corneas (either edematous or after ...
      Read Full Article
    7. Spectral-Domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology

      Spectral-Domain Optical Coherence Tomography of the Rodent Eye: Highlighting Layers of the Outer Retina Using Signal Averaging and Comparison with Histology
      Spectral-Domain Optical Coherence Tomography (SD-OCT) is a widely used method to observe retinal layers and follow pathological events in human. Recently, this technique has been adapted for animal imaging. This non-invasive technology brings a cross-sectional visualization of the retina, which permits to observe precisely each layer. There is a clear expansion of the use of this imaging modality in rodents, thus, a precise characterization of the different outer retinal layers ...
      Read Full Article
      Mentions: Michel Pâques
    8. Recognition of Henle's Fiber Layer on OCT Images

      Recognition of Henle's Fiber Layer on OCT Images
      Mons et al made an important observation about how important is to recognize the normal anatomy of the Henle's fiber layer in the optical coherence tomography images (OCT). Spectral-domain (SD) OCT offers the possibility of evaluating retinal architecture at near-histologic levels of resolution. However, clinicians should be aware that optical variations induced by examination conditions might alter the reflectivity of the retinal layers. This consideration is particularly true when ...
      Read Full Article
    9. Using Spectral-Domain Optical Coherence Tomography Imaging to Identify the Presence of Retinal Silicone Oil Emulsification After Silicone Oil Tamponade

      Using Spectral-Domain Optical Coherence Tomography Imaging to Identify the Presence of Retinal Silicone Oil Emulsification After Silicone Oil Tamponade
      Purpose: To describe small hyperreflective areas using spectral-domain optical coherence tomography (SD-OCT) imaging in eyes that have had silicone oil tamponade. Methods: Retrospective case series of 11 eyes of 11 patients. The authors retrospectively identified patients who underwent vitrectomy and silicone oil tamponade secondary to a rhegmatogenous retinal detachment (nine patients), panuveitis with retinal necrosis (one patient), or recurrent full-thickness macular hole surgery (one patient) who had manifestations of silicone ...
      Read Full Article
    10. Device For Assisting In Detecting Anatomical Features Of At Least A Portion Of A Tissue And Method For Assisting In Detecting Anatomical Features Of At Least A Portion Of A Tissue

      Device For Assisting In Detecting Anatomical Features Of At Least A Portion Of A Tissue And Method For Assisting In Detecting Anatomical Features Of At Least A Portion Of A Tissue
      The invention relates to a device for assisting in detecting anatomical features of at least a portion of a tissue, in particular a retinal tissue, the device comprising means for acquiring images of said portion using optical coherence tomography (OCT), which are taken at separate angles of incidence, and detection means for detecting, in a single area of the portion studied, at least one pattern having at least one feature ...
      Read Full Article
    11. Subretinal lymphomatous infiltration in primary intraocular lymphoma revealed by optical coherence tomography

      Subretinal lymphomatous infiltration in primary intraocular lymphoma revealed by optical coherence tomography
      Accounting for less than 1% of primary intracranial tumors, primary intraocular lymphoma (PIOL) is a subtype of primary central nervous system lymphoma [1–4]. Frequently masqueraded as chronic posterior uveitis, PIOL may involve the vitreous, retina, and/or the optic nerve. To our knowledge, there is no report of the interest of high-resolution optical coherence tomography (OCT) in PIOL. Here, we describe the case of a patient with PIOL in ...
      Read Full Article
    12. Topography of patchy retinal whitening during acute perfused retinal vein occlusion by optical coherence tomography and adaptive optics fundus imaging

      Topography of patchy retinal whitening during acute perfused retinal vein occlusion by optical coherence tomography and adaptive optics fundus imaging
      Purpose. During perfused retinal vein occlusions, patchy retinal opacification due to acute neuronal swelling may be present. This may be difficult to document using conventional imaging techniques. Methods. Three-dimensional topography of focal retinal opacification was documented in a patient with hemiretinal vein occlusion by combining en face adaptive optics (AO) imaging with high-resolution optical coherence tomography (OCT). Results. Patchy retinal opacification in the macula was faintly visible by color fundus ...
      Read Full Article
      Mentions: Michel Pâques
    13. Party 'Popper' Drugs Damage Eyes

      Party 'Popper' Drugs Damage Eyes
      Experimenting with "poppers" -- inhaled alkyl nitrates used as recreational drugs -- can cause lasting retinal damage, ophthalmologists warned. Four cases over a three-month period in France were reported in a letter to the editors appearing in the Oct. 14 issue of the New England Journal of Medicine. The prolonged visual loss likely resulted from damage to foveal photoreceptors by the acute, massive release of nitric oxide from the drugs, Michel Paques ...
      Read Full Article
      Mentions: Michel Pâques
    14. Retinal thickness measurement and evaluation of natural history of the diabetic macular edema through optical coherence tomography

      Retinal thickness measurement and evaluation of natural history of the diabetic macular edema through optical coherence tomography
      PURPOSE: 1) Diagnose, through optical coherence tomography (OCT) exam, the occurrence of diabetic macular edema in patients with diabetic retinopathy and visual acuity of 20/40 or better, by measuring the foveal center point thickness, during one year. 2) Evaluate the edema natural history, during this period, associating the center point thickness with hemoglobin A1c and changes in visual acuity. 3) Correlate the obtained results with the control group. METHODS ...
      Read Full Article
    15. Imaging of macroaneurysms occurring during retinal vein occlusion and diabetic retinopathy by indocyanine green angiography and high resolution optical coherence tomography

      Background Macular edema occurring after retinal vein occlusion (RVO) or diabetic retinopathy (DR) may be due to the development of capillary and/or venous macroaneurysms (MAs). Here, we investigated the respective contribution of fluorescein angiography (FA), of indocyanine green angiography (ICGA) and of high-resolution optical coherence tomography (HR-OCT) to their detection. Methods Review of the charts of six consecutive patients with MAs secondary to RVO (n = 4) or DR (n ...
      Read Full Article
    16. First steps toward 3D high resolution imaging using adaptive optics and full-field optical coherence tomography

      We describe here two parts of our future 3D fundus camera coupling Adaptive Optics and full-field Optical Coherence Tomography. The first part is an Adaptive Optics flood imager installed at the Quinze-Vingts Hospital, regularly used on healthy and pathological eyes. A posteriori image reconstructio ... [Proc. SPIE 7139, 713913 (2008)] published Tue Dec 30, 2008.
      Read Full Article
    17. 1-15 of 15
  1. Categories

    1. Applications:

      Art, Cardiology, Dentistry, Dermatology, Developmental Biology, Gastroenterology, Gynecology, Microscopy, NDE/NDT, Neurology, Oncology, Ophthalmology, Other Non-Medical, Otolaryngology, Pulmonology, Urology
    2. Business News:

      Acquisition, Clinical Trials, Funding, Other Business News, Partnership, Patents
    3. Technology:

      Broadband Sources, Probes, Tunable Sources
    4. Miscellaneous:

      Jobs & Studentships, Student Theses, Textbooks
  2. About Michel Pâques

    Michel Pâques is with the Centre d’Investigations Cliniques du CHNO des Quinze-Vingts, Université Paris VI.