1. Michalina J. Góra

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    1. Mentioned In 28 Articles

    2. Postdoctoral Research Fellowship in Biomedical Optics at CNRS/Strasbourg University

      Postdoctoral Research Fellowship in Biomedical Optics at CNRS/Strasbourg University
      Applicants are invited to apply for a postdoctoral researcher position in optical imaging systems for biomedical applications. The project involves the development of the novel catheter-based OCT imaging system to enhance the robotized interventional endoscope for diagnosing and treatment of diseases in the digestive system. The successful candidate will work with the research group supported by the ATIP-Avenir grant awarded by the French National Center for Scientific Research (CNRS) and ...
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    3. PhD Position at University of Strasbourg in Optical coherence tomography (OCT) for guidance of robotized interventional endoscopy

      PhD Position at University of Strasbourg in Optical coherence tomography (OCT) for guidance of robotized interventional endoscopy
      The thesis is focused on combining two unique technologies: an optical diagnostic method using optical coherence tomography (OCT) and robotized flexible endoscopy to answer a clinical need for early detection and planning of minimally invasive treatment of early stage cancer. This research project will be conducted at the ICube Laboratory (a joint Strasbourg University/CNRS research unit) and will be focused on addressing scientific and engineering challenges related to robotically ...
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    4. Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy

      Automated segmentation and characterization of esophageal wall in vivo by tethered capsule optical coherence tomography endomicroscopy
      Optical coherence tomography (OCT) is an optical diagnostic modality that can acquire cross-sectional images of the microscopic structure of the esophagus, including Barretts esophagus (BE) and associated dysplasia. We developed a swallowable tethered capsule OCT endomicroscopy (TCE) device that acquires high-resolution images of entire gastrointestinal (GI) tract luminal organs. This device has a potential to become a screening method that identifies patients with an abnormal esophagus that should be further ...
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    5. Esophageal-guided biopsy with volumetric laser endomicroscopy and laser cautery marking: a pilot clinical study

      Esophageal-guided biopsy with volumetric laser endomicroscopy and laser cautery marking: a pilot clinical study
      Background Biopsy surveillance protocols for the assessment of Barrett's esophagus can be subject to sampling errors, resulting in diagnostic uncertainty. Optical coherence tomography is a cross-sectional imaging technique that can be used to conduct volumetric laser endomicroscopy (VLE) of the entire distal esophagus. We have developed a biopsy guidance platform that places endoscopically visible marks at VLE-determined biopsy sites. Objective The objective of this study was to demonstrate in ...
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    6. Static and dynamic crystalline lens accommodation evaluated using quantitative 3-D OCT

      Static and dynamic crystalline lens accommodation evaluated using quantitative 3-D OCT
      Custom high-resolution high-speed anterior segment spectral domain Optical Coherence Tomography (OCT) provided with automatic quantification and distortion correction algorithms was used to characterize three-dimensionally (3-D) the human crystalline lens in vivo in four subjects, for accommodative demands between 0 to 6 D in 1 D steps. Anterior and posterior lens radii of curvature decreased with accommodative demand at rates of 0.73 and 0.20 mm/D, resulting in an ...
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    7. Unsedated imaging of human upper GI tract using tethered capsule endomicroscopy

      Unsedated imaging of human upper GI tract using tethered capsule endomicroscopy
      Background and Aims In order to overcome limitations of endoscopy, we have integrated a microscopic imaging technology into a tethered capsule that can be swallowed. This new technology, which we term tethered capsule endomicroscopy, provides microscopic information from the entire of esophagus as the pill passes through gastrointestinal (GI) tract. Methods Our tethered capsule endomicroscope implements a second-generation, high-speed form of optical coherence tomography termed optical frequency domain imaging that ...
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    8. 3D imaging for faster diagnosis of esophageal disease

      3D imaging for faster diagnosis of esophageal disease
      A tethered capsule that is swallowed by the patient offers a quick and pain-free method of screening and diagnosing gastrointestinal diseases. Diagnosing gastrointestinal (GI) diseases usually involves endoscopy, combining an invasive probe and video imaging or other optical methods. While effective, this method often causes patient discomfort and typically requires anesthesia, making it costly and time-consuming. Here we describe a new option for screening using a swallowable optomechanically engineered pill ...
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    9. Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin

      Interobserver Agreement for the Detection of Barrett’s Esophagus with Optical Frequency Domain Imagin
      Background Optical frequency domain imaging (OFDI) is a second-generation form of optical coherence tomography (OCT) providing comprehensive cross-sectional views of the distal esophagus at a resolution of ~7 m. Aim Using validated OCT criteria for squamous mucosa, gastric cardia mucosa, and Barretts esophagus (BE), the objective of this study was to determine the inter- and intra-observer agreements by a large number of OFDI readers for differentiating these tissues. Methods OFDI ...
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    10. Pill-sized device rivals endoscopy: Novel imaging system screens for Barrett’s esophagus in minutes

      Pill-sized device rivals endoscopy: Novel imaging system screens for Barrett’s esophagus in minutes
      P hysicians may soon have a new way to screen patients for Barretts esophagus, a precancerous condition usually caused by chronic exposure to stomach acid. Researchers at the Wellman Center for Photomedicine at Massachusetts General Hospital (MGH) have developed an imaging system enclosed in a capsule about the size of a multivitamin pill that creates detailed, microscopic images of the esophageal wall. The system has several advantages over traditional endoscopy ...
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    11. Tethered capsule endomicroscopy enables less invasive imaging of gastrointestinal tract microstructure

      Tethered capsule endomicroscopy enables less invasive imaging of gastrointestinal tract microstructure
      Here we introduce tethered capsule endomicroscopy, which involves swallowing an optomechanically engineered pill that captures cross-sectional microscopic images of the gut wall at 30 m (lateral) 7 m (axial) resolution as it travels through the digestive tract. Results in human subjects show that this technique rapidly provides three-dimensional, microstructural images of the upper gastrointestinal tract in a simple and painless procedure, opening up new opportunities for screening for internal diseases.
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    12. Corneal topography with high-speed swept source OCT in clinical examination

      Corneal topography with high-speed swept source OCT in clinical examination
      We present the applicability of high-speed swept source (SS) optical coherence tomography (OCT) for quantitative evaluation of the corneal topography. A high-speed OCT device of 108,000 lines/s permits dense 3D imaging of the anterior segment within a time period of less than one fourth of second, minimizing the influence of motion artifacts on final images and topographic analysis. The swept laser performance was specially adapted to meet imaging ...
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    13. Imaging of the lens capsule with an ultrahigh-resolution spectral optical coherence tomography prototype based on a femtosecond laser

      Aim To demonstrate the applicability of ultrahigh-speed, ultrahigh-resolution spectral optical coherence tomography (SOCT) to cross-sectional imaging of the capsular bag in vivo. Methods The ultrahigh-speed and ultrahigh-resolution SOCT prototype was designed and constructed at Nicolaus Copernicus University (Torun, Poland). To obtain an ultrahigh speed up to 100 000 lines/s a new spectrometer with fast CMOS line-scan camera was built. A femtosecond laser with a central wavelength of 780 nm ...
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    14. Applicability of Optical Coherence Tomography at 1.55 μm to the Examination of Oil Paintings

      Applicability of Optical Coherence Tomography at 1.55 μm to the Examination of Oil Paintings
      With 47 samples of commercially available oil paints, the applicability of Optical coherence tomography to noninvasive tomography of paint layers was examined. Two different instruments, utilizing near-infrared light with central wavelength of 823nm and, for the first time, 1.55 μm, were used to obtain cross-sectional images. Example tomograms are given; a ray tracing correction of images is also discussed. The tests revealed that applicability of OCT is limited to ...
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    15. Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range

      Ultra high-speed swept source OCT imaging of the anterior segment of human eye at 200 kHz with adjustable imaging range
      We present an application of in vivo anterior segment imaging of the human eye with an ultrahigh speed swept source OCT instrument. For this purpose, a dedicated OCT system was designed and constructed. This instrument enables axial zooming by automatic reconfiguration of spectral sweep range; an enhanced imaging range mode enables imaging of the entire anterior segment while a high axial resolution mode provides detailed morphological information of the chamber ...
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  2. About Michalina J. Góra

    Michalina J. Góra

    Michalina Gora is a tenure researcher at the French National Center for Scientific Research (CNRS). She is leading a research group in the ICube Laboratory in Strasbourg focused on combining optical methods with robotics for comprehensive diagnosis and improved minimally invasive treatment of diseases. Her group is currently working on the integration of optical coherence tomography into a robotized flexible endoscope to improve colorectal cancer management. She graduated from the Nicolaus Copernicus University in Poland, in 2010. Subsequently, she was a postdoctoral researcher and later a junior faculty in the team of Prof. Guillermo Tearney at the Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School in Boston.