1. Michael W. Jenkins

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    1. Mentioned In 40 Articles

    2. Complex decorrelation averaging in optical coherence tomography: a way to reduce the effect of multiple scattering and improve image contrast in a dynamic scattering medium

      Complex decorrelation averaging in optical coherence tomography: a way to reduce the effect of multiple scattering and improve image contrast in a dynamic scattering medium
      We demonstrate that complex decorrelation averaging can reduce the effect of multiple scattering and improve optical coherence tomography (OCT) imaging contrast. Complex decorrelation averaging calculates the product of an A-scan and the complex conjugate of a subsequent A-scan. The resultant signal is the product of the amplitudes and the phase difference. All these resulting complex signals at a particular location are then averaged. We take advantage of the fact that ...
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    3. Case Western Reserve University Receives 2016 NIH Grant for Optical Tools to Assess the Role of Hemodynamics in the Development of Congenital Heart Defects

      Case Western Reserve University Receives 2016 NIH Grant for Optical Tools to Assess the Role of Hemodynamics in the Development of Congenital Heart Defects
      ...Assess the Role of Hemodynamics in the Development of Congenital Heart Defects. The principal investigator is Michael Jenkins. The program began in 2015 and ends in 2020. Below is a summary of the proposed work.

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    4. Measurement Of Biomechanical Properties In An OCT Image

      Measurement Of Biomechanical Properties In An OCT Image
      Systems and method are provided for evaluating a biomechanical property of tissue. A shear wave generator is configured to induce a shear wave in the tissue. An optical coherence tomography (OCT) imager is configured to capture a B-scan frame of the tissue. An image processing component is configured to determine a frequency of the shear wave in the tissue from the B-scan frame of the tissue at each of a ...
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    5. Mapping conduction velocity of early embryonic hearts with a robust fitting algorithm

      Mapping conduction velocity of early embryonic hearts with a robust fitting algorithm
      Cardiac conduction maturation is an important and integral component of heart development. Optical mapping with voltage-sensitive dyes allows sensitive measurements of electrophysiological signals over the entire heart. However, accurate measurements of conduction velocity during early cardiac development is typically hindered by low signal-to-noise ratio (SNR) measurements of action potentials. Here, we present a novel image processing approach based on least squares optimizations, which enables high-resolution, low-noise conduction velocity mapping of ...
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    6. 3-D Stent Detection in Intravascular OCT Using a Bayesian Network and Graph Search

      3-D Stent Detection in Intravascular OCT Using a Bayesian Network and Graph Search
      Worldwide, many hundreds of thousands of stents are implanted each year to revascularize occlusions in coronary arteries. Intravascular optical coherence tomography (OCT) is an important emerging imaging technique, which has the resolution and contrast necessary to quantitatively analyze stent deployment and tissue coverage following stent implantation. Automation is needed, as current, it takes up to 16 hours to manually analyze hundreds of images and thousands of stent struts from a ...
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    7. Feature Of The Week 02/22/15: Case Western Reserve University Demostrates Using OCT to Rapidly Phenotype and Quantify Congenital Heart Defects Associated with Prenatal Alcohol Exposure

      Feature Of The Week 02/22/15:  Case Western Reserve University Demostrates Using OCT to Rapidly Phenotype and Quantify Congenital Heart Defects Associated with Prenatal Alcohol Exposure
      The most commonly used method to analyze congenital heart defects involves serial sectioning and histology. However, this is often a time-consuming process where the quantification of cardiac defects can be difficult due to problems with accurate section registration. Here we demonstrate the advantages of using optical coherence tomography, a comparatively new and rising technology, to phenotype avian embryo hearts in a model of Fetal Alcohol Syndrome where a binge-like quantity ...
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    8. Using optical coherence tomography to rapidly phenotype and quantify congenital heart defects associated with prenatal alcohol exposure

      Using optical coherence tomography to rapidly phenotype and quantify congenital heart defects associated with prenatal alcohol exposure
      Background : The most commonly used method to analyze congenital heart defects involves serial sectioning and histology. However, this is often a time-consuming process where the quantification of cardiac defects can be difficult due to problems with accurate section registration. Here we demonstrate the advantages of using optical coherence tomography, a comparatively new and rising technology, to phenotype avian embryo hearts in a model of Fetal Alcohol Syndrome where a binge-like ...
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    9. Optical coherence tomography imaging of the patent ductus arteriosus: First known uses in congenital heart disease

      Optical coherence tomography imaging of the patent ductus arteriosus: First known uses in congenital heart disease
      Background: Angiography is used to assess ductal morphology and caliber during interventional closure of the ductus arteriosus. We are evaluating the use of optical coherence tomography (OCT) to evaluate ductal anatomy given the potential benefit of superior resolution and lower radiation. Methods: Standard angiograms were performed on two patients with patent ductus arteriosus prior to device occlusion. OCT was then used to obtain high-resolution three-dimensional vessel reconstructions. Devices were chosen ...
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    10. Gated optical coherence tomography (OCT)

      Gated optical coherence tomography (OCT)
      Systems, methods, and other embodiments associated with gated optical coherence tomography (OCT) are described. One example method includes generating an image control signal to control an OCT apparatus to acquire an image of an embryonic heart at a specified point in time during a cardiac cycle of the embryonic heart. The method may also include controlling the OCT apparatus to acquire the image based on the image control signal. In ...
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    11. Three-dimensional correction of conduction velocity in the embryonic heart using integrated optical mapping and optical coherence tomography

      Three-dimensional correction of conduction velocity in the embryonic heart using integrated optical mapping and optical coherence tomography
      ...hereby improving our understanding of heart development. Pei Ma ; Yves T. Wang ; Shi Gu ; Michiko Watanabe ; Michael W. Jenkins, et al. "Three-dimensional correction of conduction velocity in the embryonic heart using ...
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  2. About Michael W. Jenkins

    Michael W. Jenkins

    Michael Jenkins received his PhD in Biomedical Engineering from Case Western Reserve University. Since 2014, he has been an Assistant Professor in the Department of Pediatrics & Biomedical Engineering, Case Western Reserve University