1. Melissa J. Suter

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    1. Mentioned In 56 Articles

    2. Distinguishing Tumor from Associated Fibrosis to Increase Diagnostic Biopsy Yield with Polarization-Sensitive Optical Coherence Tomography

      Explore Clinical Cancer Research
      Distinguishing Tumor from Associated Fibrosis to Increase Diagnostic Biopsy Yield with Polarization-Sensitive Optical Coherence Tomography
      Purpose: With recent advancements in personalized medicine, biopsies must contain sufficient tumor for histologic diagnosis and molecular testing. However, inadvertent biopsy of tumor-associated fibrosis compromises tumor yield, resulting in delayed diagnoses and/or repeat procedures when additional tumor is needed. The ability to differentiate tumor from fibrosis intraprocedurally during biopsy could significantly increase tumor yield. Polarization-sensitive optical coherence tomography (PS-OCT) is an imaging modality that is endoscope- and/or needle-compatible ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    3. Processing-based approach for resolving the sample optic axis in endoscopic polarization-sensitive optical coherence tomography

      Explore OSA | OSA Publishing Probes
      Processing-based approach for resolving the sample optic axis in endoscopic polarization-sensitive optical coherence tomography
      Fiber-based polarization-sensitive optical coherence tomography (PS-OCT) that utilizes a rotationally-scanning catheter has a variety of potential biomedical applications in luminal organ systems due to its ability to provide intrinsic contrast for birefringent tissue. Incorporating the optic axis (OA) of the tissue greatly enhances this potential by also permitting information about the orientation of the tissue to be extracted; however, measurement distortion that occurs has up to this point made it ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    4. Nano-optic endoscope for high-resolution optical coherence tomography in vivo

      Explore Nature Publishing Group Gastroenterology , Probes
      Nano-optic endoscope for high-resolution optical coherence tomography in vivo
      Acquisition of high-resolution images from within internal organs using endoscopic optical imaging has numerous clinical applications. However, difficulties associated with optical aberrations and the trade-off between transverse resolution and depth of focus significantly limit the scope of applications. Here, we integrate a metalens, with the ability to modify the phase of incident light at subwavelength level, into the design of an endoscopic optical coherence tomography catheter (termed nano-optic endoscope) to ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    5. Needle-based Optical Coherence Tomography to Guide Transbronchial Lymph Node Biopsy

      Explore LWW Online Pulmonology
      Needle-based Optical Coherence Tomography to Guide Transbronchial Lymph Node Biopsy
      Background: Transbronchial needle aspiration (TBNA), often used to sample lymph nodes for lung cancer staging , is subject to sampling error even when performed with endobronchial ultrasound. Optical coherence tomography (OCT) is a high-resolution imaging modality that rapidly generates helical cross-sectional images. We aim to determine if needle-based OCT can provide microstructural information in lymph nodes that may be used to guide TBNA, and improve sampling error. Methods: We performed ex ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    6. Optical coherence tomography (OCT) imaging of dynamic airway behavior in an asthma model

      Explore SPIE Digital Library Pulmonology
      Optical coherence tomography (OCT) imaging of dynamic airway behavior in an asthma model
      To better understand bronchoconstriction in asthma, it is critical to dynamically visualize airway behavior in vivo. However, currently available imaging techniques do not have sufficient temporal and spatial resolution to investigate airway dynamics. We propose to use endobronchial Optical Coherence Tomography (OCT) to provide real-time cross-sectional images of airway dynamics with a high spatial resolution. Our aim was to study the structure and function of spatially distinct airways during tidal ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    7. Automated segmentation and quantification of airway mucus with endobronchial optical coherence tomography

      Explore OSA | OSA Publishing Pulmonology
      Automated segmentation and quantification of airway mucus with endobronchial optical coherence tomography
      We propose a novel suite of algorithms for automatically segmenting the airway lumen and mucus in endobronchial optical coherence tomography (OCT) data sets, as well as a novel approach for quantifying the contents of the mucus. Mucus and lumen were segmented using a robust, multi-stage algorithm that requires only minimal input regarding sheath geometry. The algorithm performance was highly accurate in a wide range of airway and noise conditions. Mucus ...
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      Mentions: Massachusetts General Hospital Harvard University University of North Carolina

    9. Massachusetts General Hospital Receives NIH Grant for Low Risk In VIvo Optical Diagnosis of IPF with Optical Imaging

      Explore Optical Coherence Tomography News Pulmonology , Funding
      Massachusetts General Hospital Receives NIH Grant for Low Risk In VIvo Optical Diagnosis of IPF with Optical Imaging
      ...aborative opportunities, and access to all the necessary resources to conduct her research. Her mentors, Drs. Melissa Suter and Andrew Tager, are luminaries in their respective fields of clinical optical imaging and pulm...
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      Mentions: Brett E. Bouma National Institutes of Health Massachusetts General Hospital

    10. Apparatus and method to compensate for input polarization mode variation

      Explore uspto.gov Patents
      Apparatus and method to compensate for input polarization mode variation
      Exemplary apparatus and method can be provided. For example, with at least one first arrangement, it is possible to provide at least one first radiation, which can impact at least one second arrangement that is provided in an optical path between the at least one first arrangement(s) and at least sample. The second arrangement can have at least one birefringent property, In addition, with at least one detector third ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    11. Endoscopic biopsy apparatus, system and method

      Explore uspto.gov Patents , Probes
      Endoscopic biopsy apparatus, system and method
      Exemplary embodiments of apparatus, method and system for determining a position on or in a biological tissue can be provided. For example, using such exemplary embodiment, it is possible to control the focus of an optical imaging probe. In another exemplary embodiment, it is possible to implement a marking apparatus together with or into an optical imaging probe. According to one exemplary embodiment, it is possible (using one or more ...
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      Mentions: Guillermo J. Tearney Brett E. Bouma Massachusetts General Hospital

    12. Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo

      Explore Science Translational Medicine Pulmonology
      Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo
      The inability to visualize airway smooth muscle (ASM) cells in vivo is a major obstacle in understanding their role in normal physiology and diseases. At present, there is no imaging modality available to assess ASM in vivo. Confocal endomicroscopy lacks the penetration depth and field of view, and conventional optical coherence tomography (OCT) does not have sufficient contrast to differentiate ASM from surrounding tissues. We have developed a birefringence microscopy ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    13. Mass. General studies identify differences underlying the airway responses of patients with asthma

      Explore Massachusetts General Hospital Home Pulmonology
      Mass. General studies identify differences underlying the airway responses of patients with asthma
      ...uring an asthma attack. This was made possible by a novel imaging technique develop by the other team, led by Melissa Suter, PhD, of the MGH Division of Pulmonary and Critical Care Medicine. They developed an advanced ve...
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      Mentions: National Institutes of Health Massachusetts General Hospital Harvard University

    16. Multi-laboratory inter-institute reproducibility study of IVOCT and IVUS assessments using published consensus document definitions

      Explore ehjcimaging.oxfordjournals.org Cardiology
      Multi-laboratory inter-institute reproducibility study of IVOCT and IVUS assessments using published consensus document definitions
      Aims The aim of this study was to investigate the reproducibility of intravascular optical coherence tomography (IVOCT) assessments, including a comparison to intravascular ultrasound (IVUS). Intra-observer and inter-observer variabilities of IVOCT have been previously described, whereas inter-institute reliability in multiple laboratories has never been systematically studied. Methods and results In 2 independent laboratories with intravascular imaging expertise, 100 randomized matched data sets of IVOCT and IVUS images were analysed by ...
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      Mentions: Guillermo J. Tearney Brett E. Bouma Columbia University
    17. 1-15 of 56 1 2 3 4 »
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  4. About Melissa J. Suter

    Melissa J. Suter

    Melissa J. Suter is a Assistant Professor of Medicine in the, Department Medicine in the Pulmonary and Critical Care Unit at Massachusetts General Hospital.

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