1. Melissa J. Suter

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    1. Mentioned In 52 Articles

    2. Needle-based Optical Coherence Tomography to Guide Transbronchial Lymph Node Biopsy

      Explore LWW Online Pulmonology
      Needle-based Optical Coherence Tomography to Guide Transbronchial Lymph Node Biopsy
      Background: Transbronchial needle aspiration (TBNA), often used to sample lymph nodes for lung cancer staging , is subject to sampling error even when performed with endobronchial ultrasound. Optical coherence tomography (OCT) is a high-resolution imaging modality that rapidly generates helical cross-sectional images. We aim to determine if needle-based OCT can provide microstructural information in lymph nodes that may be used to guide TBNA, and improve sampling error. Methods: We performed ex ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    3. Optical coherence tomography (OCT) imaging of dynamic airway behavior in an asthma model

      Explore SPIE Digital Library Pulmonology
      Optical coherence tomography (OCT) imaging of dynamic airway behavior in an asthma model
      To better understand bronchoconstriction in asthma, it is critical to dynamically visualize airway behavior in vivo. However, currently available imaging techniques do not have sufficient temporal and spatial resolution to investigate airway dynamics. We propose to use endobronchial Optical Coherence Tomography (OCT) to provide real-time cross-sectional images of airway dynamics with a high spatial resolution. Our aim was to study the structure and function of spatially distinct airways during tidal ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    4. Automated segmentation and quantification of airway mucus with endobronchial optical coherence tomography

      Explore OSA | OSA Publishing Pulmonology
      Automated segmentation and quantification of airway mucus with endobronchial optical coherence tomography
      We propose a novel suite of algorithms for automatically segmenting the airway lumen and mucus in endobronchial optical coherence tomography (OCT) data sets, as well as a novel approach for quantifying the contents of the mucus. Mucus and lumen were segmented using a robust, multi-stage algorithm that requires only minimal input regarding sheath geometry. The algorithm performance was highly accurate in a wide range of airway and noise conditions. Mucus ...
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      Mentions: Massachusetts General Hospital Harvard University University of North Carolina

    6. Massachusetts General Hospital Receives NIH Grant for Low Risk In VIvo Optical Diagnosis of IPF with Optical Imaging

      Explore Optical Coherence Tomography News Pulmonology , Funding
      Massachusetts General Hospital Receives NIH Grant for Low Risk In VIvo Optical Diagnosis of IPF with Optical Imaging
      ...aborative opportunities, and access to all the necessary resources to conduct her research. Her mentors, Drs. Melissa Suter and Andrew Tager, are luminaries in their respective fields of clinical optical imaging and pulm...
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      Mentions: Brett E. Bouma National Institutes of Health Massachusetts General Hospital

    7. Apparatus and method to compensate for input polarization mode variation

      Explore uspto.gov Patents
      Apparatus and method to compensate for input polarization mode variation
      Exemplary apparatus and method can be provided. For example, with at least one first arrangement, it is possible to provide at least one first radiation, which can impact at least one second arrangement that is provided in an optical path between the at least one first arrangement(s) and at least sample. The second arrangement can have at least one birefringent property, In addition, with at least one detector third ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    8. Endoscopic biopsy apparatus, system and method

      Explore uspto.gov Patents , Probes
      Endoscopic biopsy apparatus, system and method
      Exemplary embodiments of apparatus, method and system for determining a position on or in a biological tissue can be provided. For example, using such exemplary embodiment, it is possible to control the focus of an optical imaging probe. In another exemplary embodiment, it is possible to implement a marking apparatus together with or into an optical imaging probe. According to one exemplary embodiment, it is possible (using one or more ...
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      Mentions: Guillermo J. Tearney Brett E. Bouma Massachusetts General Hospital

    9. Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo

      Explore Science Translational Medicine Pulmonology
      Birefringence microscopy platform for assessing airway smooth muscle structure and function in vivo
      The inability to visualize airway smooth muscle (ASM) cells in vivo is a major obstacle in understanding their role in normal physiology and diseases. At present, there is no imaging modality available to assess ASM in vivo. Confocal endomicroscopy lacks the penetration depth and field of view, and conventional optical coherence tomography (OCT) does not have sufficient contrast to differentiate ASM from surrounding tissues. We have developed a birefringence microscopy ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    10. Mass. General studies identify differences underlying the airway responses of patients with asthma

      Explore Massachusetts General Hospital Home Pulmonology
      Mass. General studies identify differences underlying the airway responses of patients with asthma
      ...uring an asthma attack. This was made possible by a novel imaging technique develop by the other team, led by Melissa Suter, PhD, of the MGH Division of Pulmonary and Critical Care Medicine. They developed an advanced ve...
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      Mentions: National Institutes of Health Massachusetts General Hospital Harvard University

    13. Multi-laboratory inter-institute reproducibility study of IVOCT and IVUS assessments using published consensus document definitions

      Explore ehjcimaging.oxfordjournals.org Cardiology
      Multi-laboratory inter-institute reproducibility study of IVOCT and IVUS assessments using published consensus document definitions
      Aims The aim of this study was to investigate the reproducibility of intravascular optical coherence tomography (IVOCT) assessments, including a comparison to intravascular ultrasound (IVUS). Intra-observer and inter-observer variabilities of IVOCT have been previously described, whereas inter-institute reliability in multiple laboratories has never been systematically studied. Methods and results In 2 independent laboratories with intravascular imaging expertise, 100 randomized matched data sets of IVOCT and IVUS images were analysed by ...
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      Mentions: Guillermo J. Tearney Brett E. Bouma Columbia University

    14. Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study

      Explore Home - Springer Cardiology
      Optimizing flushing parameters in intracoronary optical coherence tomography: an in vivo swine study
      Intracoronary optical frequency domain imaging (OFDI), requires the displacement of blood for clear visualization of the artery wall. Radiographic contrast agents are highly effective at displacing blood however, may increase the risk of contrast-induced nephropathy. Flushing media viscosity, flow rate, and flush duration influence the efficiency of blood displacement necessary for obtaining diagnostic quality OFDI images. The aim of this work was to determine the optimal flushing parameters necessary to ...
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      Mentions: Guillermo J. Tearney Brett E. Bouma Massachusetts General Hospital

    15. Diagnosing Lung Carcinomas with Optical Coherence Tomography

      Explore Home (thoracic) Pulmonology
      Diagnosing Lung Carcinomas with Optical Coherence Tomography
      Rationale: Lung carcinoma diagnosis on tissue biopsy can be challenging due to insufficient tumor and lack of architectural information. Optical coherence tomography (OCT) is a high-resolution imaging modality that visualizes tissue microarchitecture in volumes orders of magnitude larger than biopsy. It has been proposed that OCT could potentially replace tissue biopsy. Objectives: We aim to determine if OCT could replace histology in diagnosing lung carcinomas . We develop and validate OCT ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    16. Postdoctoral Research Fellow Opening in Pulmonary and Critical Care Unit at Massachusetts General Hospital

      Explore Optical Coherence Tomography News Pulmonology , Jobs & Studentships
      Postdoctoral Research Fellow Opening in Pulmonary and Critical Care Unit at Massachusetts General Hospital
      ...ing relevant training and research experience, and the names and contact information of three referees to Dr. Melissa Suter, PhD, msuter@mgh.harvard.edu

      A postdoctoral research opportunity in biomedical optics is avai...

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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter
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  4. About Melissa J. Suter

    Melissa J. Suter

    Melissa J. Suter is a Assistant Professor of Medicine in the, Department Medicine in the Pulmonary and Critical Care Unit at Massachusetts General Hospital.

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