1. Melinda Sanders

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    1. Mentioned In 9 Articles

    2. Classification of human ovarian tissue using full field optical coherence tomography

      Classification of human ovarian tissue using full field optical coherence tomography
      The feasibility of a full-field optical coherence tomography (FFOCT) system for rapid wide field optical analysis of normal and malignant human ovarian tissue pathologies was demonstrated. Five features were extracted from the normalized image histogram from 56 FFOCT images, based on the differences in the morphology of the normal and malignant tissue samples.
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    3. Classification and analysis of human ovarian tissue using full field optical coherence tomography

      Classification and analysis of human ovarian tissue using full field optical coherence tomography
      In this study, a full field optical coherence tomography (FFOCT) system was used to analyze and classify normal and malignant human ovarian tissue. 14 ovarian tissue samples (7 normal, 7 malignant) were imaged with the FFOCT system and five features were extracted by analyzing the normalized image histogram from 56 FFOCT images, based on the differences in the morphology of the normal and malignant tissue samples. A generalized linear model ...
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    4. Correlating optical coherence elastography based strain measurements with collagen content of the human ovarian tissue

      Correlating optical coherence elastography based strain measurements with collagen content of the human ovarian tissue
      In this manuscript, the initial feasibility of a catheter based phase stabilized swept source optical coherence tomography (OCT) system was studied for characterization of the strain inside different human ovarian tissue groups. The ovarian tissue samples were periodically compressed with 500 Hz square wave signal along the axial direction between the surface of an unfocused transducer and a glass cover slide. The displacement and corresponding strain were calculated during loading ...
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    5. Assessment of collagen changes in ovarian tissue by extracting optical scattering coefficient from OCT images

      Assessment of collagen changes in ovarian tissue by extracting optical scattering coefficient from OCT images
      Optical scattering coefficient from ex-vivo unfixed normal and malignant ovarian tissue was quantitatively extracted by fitting optical coherence tomography (OCT) A-line signals to a single scattering model. 1097 average A-line measurements at a wavelength of 1310nm were performed at 108 sites obtained from 18 ovaries. The average scattering coefficient obtained from normal group consisted of 833 measurements from 88 sites was 2.41 mm-1 (±0.59), while the average coefficient ...
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    6. Feature Of The Week 10/23/11: Hybrid Intraoperative Probe Based on OCT and Positron Detection for Ovarian Cancer Detection

      Feature Of The Week 10/23/11: Hybrid Intraoperative Probe Based on OCT and Positron Detection for Ovarian Cancer Detection
      Multi-modality imaging involving OCT and one or more additional imaging technologies continues to show very promising results for increasing the diagnostic and interventional guidance capability of biomedical imaging probes. These synergistic effects have been published in numerous papers over the past year. This includes OCT in combination with fluorescence, Raman, NIR, ultrasound, and other technologies. Such approaches have the obvious disadvantage of increasing the cost and complexity of the imaging ...
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    7. Potential role of a hybrid intraoperative probe based on OCT and positron detection for ovarian cancer detection and characterization

      Potential role of a hybrid intraoperative probe based on OCT and positron detection for ovarian cancer detection and characterization
      ...itation Yi Yang, Nrusingh C. Biswal, Tianheng Wang, Patrick D. Kumavor, Mozafareddin Karimeddini, John Vento, Melinda Sanders, Molly Brewer, and Quing Zhu, "Potential role of a hybrid intraoperative probe based on OCT an...
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  2. About Melinda Sanders

    Melinda Sanders

    Melinda Sanders is a professor and chair of the pathology and laboratory medicine department at the University of Connecticut Health Center.