1. Medical University of Vienna

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    1. Mentioned In 553 Articles

    2. MHz Swept Source Optical Coherence Tomography of the Choriocapillaris

      MHz Swept Source Optical Coherence Tomography of the Choriocapillaris
      Purpose : Resolving individual capillaries of the choriocapillaris with swept source optical coherence tomography (SS-OCT) angiography is challenging and has so far been limited to very small field of views (FOV). We present a MHz SS-OCT prototype, which provides high-contrast choriocapillaris (CC) images. Methods : We developed a 1060 nm SS-OCT prototype, capable of A-scan rates up to 1.7 MHz. Its lateral resolution was 7.8 m and its axial resolution ...
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    3. New imaging system to detect bowel cancer at the earliest stages using photonics

      New imaging system to detect bowel cancer at the earliest stages using photonics
      ...isease," said Andersen. Concluding in 2024, the PROSCOPE project will conduct future trials at clinics at the Medical University of Vienna. The four-year PROSCOPE project received a grant of €5,999,383.75 from Horizon 20...
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    4. Role of anterior segment optical coherence tomography angiography in the assessment of acute chemical ocular injury: a pilot animal model study

      Role of anterior segment optical coherence tomography angiography in the assessment of acute chemical ocular injury: a pilot animal model study
      To examine the use of anterior segment-optical coherence tomography angiography (AS-OCTA) in the assessment of limbal ischemia in an animal model chemical ocular injury. We conducted a prospective study using an established chemical ocular injury model in 6 rabbits (12 eyes), dividing the cornea limbus into 4 quadrants. Chemical injury grade was induced based on extent of limbal injury (0 to 360 degrees) and all eyes underwent serial slit-lamp with ...
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    5. Fundus autofluorescence and optical coherence tomography biomarkers associated with the progression of geographic atrophy secondary to age-related macular degeneration

      Fundus autofluorescence and optical coherence tomography biomarkers associated with the progression of geographic atrophy secondary to age-related macular degeneration
      Objectives To investigate the impact of qualitatively graded and deep learning quantified imaging biomarkers on growth of geographic atrophy (GA) secondary to age-related macular degeneration. Methods This prospective study included 1062 visits of 181 eyes of 100 patients with GA. Spectral-domain optical coherence tomography (SD-OCT) and fundus autofluorescence (FAF) images were acquired at each visit. Hyperreflective foci (HRF) were quantitatively assessed in SD-OCT volumes using a validated deep learning algorithm ...
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    6. Developing a normative database for retinal perfusion using optical coherence tomography angiography

      Developing a normative database for retinal perfusion using optical coherence tomography angiography
      Visualizing and characterizing microvascular abnormalities with optical coherence tomography angiography (OCTA) has deepened our understanding of ocular diseases, such as glaucoma, diabetic retinopathy, and age-related macular degeneration. Two types of microvascular defects can be detected by OCTA: focal decrease because of localized absence and collapse of retinal capillaries, which is referred to as the non-perfusion area in OCTA, and diffuse perfusion decrease usually detected by comparing with healthy case-control groups ...
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    7. Optical coherence tomography-measured retinal nerve fiber layer thickness values compensated with a multivariate model and discrimination between stable and progressing glaucoma suspects

      Optical coherence tomography-measured retinal nerve fiber layer thickness values compensated with a multivariate model and discrimination between stable and progressing glaucoma suspects
      Purpose Our previously introduced multivariate model, compensating for intersubject variability, was applied to circumpapillary retinal nerve fiber layer (RNFL) values measured with optical coherence tomography in glaucoma suspects with or without prior progressive optic disc (OD) change in a series of confocal scanning laser tomography (CSLT, HRT III) measurements. Methods In this prospective study, OD change during CSLT follow-up was determined with strict, moderate, and liberal criteria of the topographic ...
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    8. Impact of large choroidal vessels on choriocapillaris flow deficit analyses in optical coherence tomography angiography

      Impact of large choroidal vessels on choriocapillaris flow deficit analyses in optical coherence tomography angiography
      Purpose To investigate the impact of large choroidal vessels (LCV) on Choriocapillaris (CC) flow deficit (FD) analyses with swept-source optical coherence tomography angiography (SS-OCTA) Design Prospective, cross-sectional study. Methods Macular 6x6mm SS-OCTA scans were obtained from intermediate age-related macular degeneration (iAMD) and healthy eyes. Images were captured and processed according to most common standards and analyzed for percentage of flow-deficits (FD%) within four 1x1mm squares at the corners of each ...
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    9. Framework for quantitative three-dimensional choroidal vasculature analysis using optical coherence tomography

      Framework for quantitative three-dimensional choroidal vasculature analysis using optical coherence tomography
      Choroidal vasculature plays an important role in the pathogenesis of retinal diseases, such as myopic maculopathy, age-related macular degeneration, diabetic retinopathy, central serous chorioretinopathy, and ocular inflammatory diseases. Current optical coherence tomography (OCT) technology provides three-dimensional visualization of the choroidal angioarchitecture; however, quantitative measures remain challenging. Here, we propose and validate a framework to segment and quantify the choroidal vasculature from a prototype swept-source OCT (PLEX Elite 9000, Carl Zeiss ...
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    10. Navigated, Robot-Driven Laser Craniotomy for SEEG Application Using Optical Coherence Tomography in an Animal Model

      Navigated, Robot-Driven Laser Craniotomy for SEEG Application Using Optical Coherence Tomography in an Animal Model
      Objectives: We recently introduced a navigated, robot-driven laser beam craniotomy for use with stereoelectroencephalography (SEEG) applications. This method was intended to substitute the hand-held electric power drill in an ex vivo study. The purpose of this in vivo non-recovery pilot study was to acquire data for the depth control unit of this laser device, to test the feasibility of cutting bone channels, and to assess dura perforation and possible cortex ...
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    11. Deep Learning–Based Automated Optical Coherence Tomography Segmentation in Clinical Routine: Getting Closer

      Deep Learning–Based Automated Optical Coherence Tomography Segmentation in Clinical Routine: Getting Closer
      Recently, many ophthalmologists have heard the keywords artificial intelligence , machine learning , deep learning , and automatization at every conference and keynote lecture and seen them in every ophthalmology journal. 1 Many studies 1 have evaluated the use of such algorithms on large retrospective data setsprimarily on color fundus photographs at first, then on optical coherence tomography (OCT) images as well. Most of these have been study data sets with standardized and ...
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    12. Segregation of neuronal-vascular components in a retinal nerve fiber layer for thickness measurement using OCT and OCT angiography

      Segregation of neuronal-vascular components in a retinal nerve fiber layer for thickness measurement using OCT and OCT angiography
      Assessment of the circumpapillary retinal nerve fiber layer (RNFL) provides crucial knowledge on the status of the optic nerve. Current circumpapillary RNFL measurements consider only thickness, but an accurate evaluation should also consider blood vessel contribution. Previous studies considered the presence of major vessels in RNFL thickness measurements from optical coherence tomography (OCT). However, such quantitative measurements do not account for smaller vessels, which could also affect circumpapillary RNFL measurements ...
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    13. Morpho-Molecular Metabolic Analysis and Classification of Human Pituitary Gland and Adenoma Biopsies Based on Multimodal Optical Imaging

      Morpho-Molecular Metabolic Analysis and Classification of Human Pituitary Gland and Adenoma Biopsies Based on Multimodal Optical Imaging
      Pituitary adenomas count among the most common intracranial tumors. During pituitary oncogenesis structural, textural, metabolic and molecular changes occur which can be revealed with our integrated ultrahigh-resolution multimodal imaging approach including optical coherence tomography (OCT), multiphoton microscopy (MPM) and line scan Raman microspectroscopy (LSRM) on an unprecedented cellular level in a label-free manner. We investigated 5 pituitary gland and 25 adenoma biopsies, including lactotroph, null cell, gonadotroph, somatotroph and mammosomatotroph ...
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    14. Adaptive compounding speckle-noise-reduction filter for optical coherence tomography images

      Adaptive compounding speckle-noise-reduction filter for optical coherence tomography images
      Significance: Speckle noise limits the diagnostic capabilities of optical coherence tomography (OCT) images, causing both a reduction in contrast and a less accurate assessment of the microstructural morphology of the tissue. Aim: We present a speckle-noise reduction method for OCT volumes that exploits the advantages of adaptive-noise wavelet thresholding with a wavelet compounding method applied to several frames acquired from consecutive positions. The method takes advantage of the wavelet representation ...
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    15. Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Des

      Effects of the PCSK9 Antibody Alirocumab on Coronary Atherosclerosis in Patients with Acute Myocardial Infarction: A Serial, Multivessel, Intravascular Ultrasound, Near-Infrared Spectroscopy and Optical Coherence Tomography Imaging Study Rationale and Des
      Background: The risk for cardiovascular adverse events after acute myocardial infarction (AMI) remains high despite potent medical treatment including low-density lipoprotein cholesterol (LDL-C) lowering with statins. Proprotein convertase subtilisin/kexin type 9 (PCSK9) antibodies substantially reduce LDL-C when added to statin. Alirocumab, a momoclonal antibody to PCSK9, reduces major adverse cardiovascular events after AMI. The effects of alirocumab on coronary atherosclerosis including plaque burden, plaque composition and fibrous cap thickness ...
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    16. 1-15 of 553 1 2 3 4 ... 35 36 37 »
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  2. About Medical University of Vienna

    Medical University of Vienna

    Medical University of Vienna.  In its structuring and alignment the Medical University of Vienna relies on the "triple track" strategy. Research, education and patient care represent the three cornerstones of the university's system. Center for Biomedical Engineering and Physics, Medical University of Vienna, Austria.  The Biomedical Engineering Group at the Department of Biomedical Engineering of the Medical School, University of Vienna, is situated in the University Hospital of Vienna, which is the biggest hospital of Austria, and one of the biggest in Europe. The Biomedical Engineering Group was concentrated here to promote medical research with modern technical means.