1. Medical University of Vienna

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    1. Mentioned In 593 Articles

    2. Multi-modal and multi-scale clinical retinal imaging system with pupil and retinal tracking

      Multi-modal and multi-scale clinical retinal imaging system with pupil and retinal tracking
      We present a compact multi-modal and multi-scale retinal imaging instrument with an angiographic functional extension for clinical use. The system integrates scanning laser ophthalmoscopy (SLO), optical coherence tomography (OCT) and OCT angiography (OCTA) imaging modalities and provides multi-scale fields of view. For high resolution, and high lateral resolution in particular, cellular imaging correction of aberrations by adaptive optics (AO) is employed. The entire instrument has a compact design and the ...
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    3. The effect of pegcetacoplan treatment on photoreceptor maintenance in geographic atrophy monitored by AI-based OCT analysis

      The effect of pegcetacoplan treatment on photoreceptor maintenance in geographic atrophy monitored by AI-based OCT analysis
      Purpose: To investigate the therapeutic effect of intravitreal pegcetacoplan on the inhibition of photoreceptor (PR) loss and thinning in geographic atrophy (GA) on conventional spectral domain-optical coherence tomography (SD-OCT) imaging by deep learning-based automated PR quantification. Design: Post-hoc analysis of a prospective, multicenter, randomized, sham-controlled, masked phase II trial investigating the safety and efficacy of pegcetacoplan for the treatment of GA due to age-related macular degeneration. Participants: Study eyes of ...
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    4. Special Issue "Biomedical Applications of Optical Coherence Tomography" in the journal of Bioengineering

      Special Issue "Biomedical Applications of Optical Coherence Tomography" in the journal of Bioengineering
      Dear Colleagues, Since its invention in 1991, optical coherence tomography (OCT) has rapidly become one of the most important clinical tools in the field of ophthalmology. In recent years, applications of this inherently non-invasive and label-free three-dimensional imaging technique have extended far beyond retinal and corneal imaging. OCT applications are being increasingly used in medicine in fields including dermatology, endoscopy and neurology, and advances in system technology and image processing ...
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    5. The New Era of Retinal Imaging in Hypertensive Patients

      The New Era of Retinal Imaging in Hypertensive Patients
      Structural and functional alterations in the microcirculation by systemic hypertension can cause significant organ damage at the eye, heart, brain, and kidneys. As the retina is the only tissue in the body that allows direct imaging of small vessels, the relationship of hypertensive retinopathy signs with development of disease states in other organs have been extensively studied; large-scale epidemiological studies using fundus photography and advanced semi-automated analysis software have reported ...
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    6. A multi-regression approach to improve optical coherence tomography diagnostic accuracy in multiple sclerosis patients without previous optic neuritis

      A multi-regression approach to improve optical coherence tomography diagnostic accuracy in multiple sclerosis patients without previous optic neuritis
      Background: Optical coherence tomography (OCT) is a retinal imaging system that may improve the diagnosis of multiple sclerosis (MS) persons, but the evidence is currently equivocal. To assess whether compensating the peripapillary retinal nerve fiber layer (pRNFL) thickness for ocular anatomical features as well as the combination with macular layers can improve the capability of OCT in differentiating non-optic neuritis eyes of relapsing-remitting MS patients from healthy controls. Methods: 74 ...
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    7. Evaluation of neuroretinal integrity in optical coherence tomography-graded eyes with partial-thickness macular holes

      Evaluation of neuroretinal integrity in optical coherence tomography-graded eyes with partial-thickness macular holes
      Purpose: To evaluate neuroretinal integrity in different subtypes of optical coherence tomography (OCT)-graded partial-thickness macular holes. Methods: Fovea-centred SD-OCT images (Cirrus, Carl Zeiss Meditec AG; Spectralis, Heidelberg Engineering GmbH) and visual acuity (VA) acquired at every visit were analysed by two retina specialists retrospectively in 71 eyes of 65 patients. Partial-thickness macular holes were classified as lamellar macular hole (LMH), epiretinal membrane foveoschisis (ERMF) or macular pseudohole (MPH). Results ...
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    8. New Imaging Procedures and Therapeutic Approach in Basal Cell Carcinoma Management

      New Imaging Procedures and Therapeutic Approach in Basal Cell Carcinoma Management
      The aim of this study is to show that the Nd:YAG laser could be a promising alternative treatment option in the management of low-risk basal cell carcinomas with similar high efficacy rates to surgery, and low recurrence rates evaluated over a time period of one year. Reflectance confocal microscopy, optical coherence tomography and clinical examination are used prior to confirm the clinical diagnosis of the basal cell carcinoma and ...
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    9. Robust Fovea Detection in Retinal OCT Imaging using Deep Learning

      Robust Fovea Detection in Retinal OCT Imaging using Deep Learning
      The fovea centralis is an essential landmark in the retina where the photoreceptor layer is entirely composed of cones responsible for sharp, central vision. The localization of this anatomical landmark in optical coherence tomography (OCT) volumes is important for assessing visual function correlates and treatment guidance in macular disease. In this study, the "PRE U-net" is introduced as a novel approach for a fully automated fovea centralis detection, addressing the ...
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    10. Non-destructive characterization of adult zebrafish models using Jones matrix optical coherence tomography

      Non-destructive characterization of adult zebrafish models using Jones matrix optical coherence tomography
      The zebrafish is a valuable vertebrate animal model in pre-clinical cancer research. A Jones matrix optical coherence tomography (JM-OCT) prototype operating at 1310 nm and an intensity-based spectral-domain OCT setup at 840 nm were utilized to investigate adult wildtype and a tumor-developing zebrafish model. Various anatomical features were characterized based on their inherent scattering and polarization signature. A motorized translation stage in combination with the JM-OCT prototype enabled large field-of-view ...
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    11. A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer’s disease

      A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer’s disease
      Background Diagnostic performance of optical coherence tomography (OCT) to detect Alzheimers disease (AD) and mild cognitive impairment (MCI) remains limited. We assessed whether compensating the circumpapillary retinal nerve fiber layer (cpRNFL) thickness for multiple demographic and anatomical factors as well as the combination of macular layers improves the detection of MCI and AD. Methods This cross-sectional study of 62 AD ( n =92 eyes), 108 MCI ( n =158 eyes), and 55 ...
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    12. Automatic segmentation of intraocular lens, the retrolental space and Berger's space using deep learning

      Automatic segmentation of intraocular lens, the retrolental space and Berger's space using deep learning
      Purpose To develop and validate a deep learning model to automatically segment three structures using an anterior segment optical coherence tomography (AS-OCT): The intraocular lens (IOL), the retrolental space (IOL to the posterior lens capsule) and Berger's space (BS; posterior capsule to the anterior hyaloid membrane). Methods An artificial intelligence (AI) approach based on a deep learning model to automatically segment the IOL, the retrolental space, and BS in ...
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    13. Anterior Segment Optical Coherence Tomography Angiography Following Trabecular Bypass Minimally Invasive Glaucoma Surgery

      Anterior Segment Optical Coherence Tomography Angiography Following Trabecular Bypass Minimally Invasive Glaucoma Surgery
      Objective: To assess anterior segment optical coherence tomography angiography (AS-OCTA) imaging of the episcleral vessels before and after trabecular bypass minimally invasive glaucoma surgery (MIGS). Design: A prospective, clinical, single-centre, single-arm pilot feasibility study conducted at National University Hospital, Singapore. Subjects: Patients with primary glaucomatous optic neuropathy undergoing Hydrus Microstent (Ivantis Inc., Irvine, CA, USA) implantation, who require at least one intra-ocular pressure-lowering medication. One or two eyes per patient ...
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    14. A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer’s disease

      A multi-regression framework to improve diagnostic ability of optical coherence tomography retinal biomarkers to discriminate mild cognitive impairment and Alzheimer’s disease
      Background: Diagnostic performance of optical coherence tomography (OCT) to detect Alzheimer's disease (AD) and mild cognitive impairment (MCI) remains limited. We assessed whether compensating the circumpapillary retinal nerve fiber layer (cpRNFL) thickness for multiple demographic and anatomical factors as well as the combination of macular layers improves the detection of MCI and AD. Methods: This cross-sectional study of 62 AD (n = 92 eyes), 108 MCI (n = 158 eyes), and ...
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    15. 1-15 of 593 1 2 3 4 ... 38 39 40 »
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  2. About Medical University of Vienna

    Medical University of Vienna

    Medical University of Vienna.  In its structuring and alignment the Medical University of Vienna relies on the "triple track" strategy. Research, education and patient care represent the three cornerstones of the university's system. Center for Biomedical Engineering and Physics, Medical University of Vienna, Austria.  The Biomedical Engineering Group at the Department of Biomedical Engineering of the Medical School, University of Vienna, is situated in the University Hospital of Vienna, which is the biggest hospital of Austria, and one of the biggest in Europe. The Biomedical Engineering Group was concentrated here to promote medical research with modern technical means.