1. Matti Kinnunen

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    1. Mentioned In 9 Articles

    2. Optical clearing of articular cartilage: a comparison of clearing agents

      Optical clearing of articular cartilage: a comparison of clearing agents
      Optical clearing technique was applied to the problem of OCT imaging of articular cartilage and subchondral bone. We show that optical clearing significantly enhances visualization of articular cartilage and cartilage-bone interface. The effect of different clearing agents was analyzed. For the clearing, iohexol solution and propylene glycol (PG) were used. Clearing was performed in vitro at room temperature by immersion method. Cylindrical osteochondral samples (d=4.8mm) were drilled from ...
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    3. Imaging of subchondral bone by optical coherence tomography upon optical clearing of articular cartilage

      Imaging of subchondral bone by optical coherence tomography upon optical clearing of articular cartilage
      Optical clearing is an effective method to reduce light scattering of biological tissues that provides significant enhancement of light penetration into the biological tissues making non-invasive diagnosis more feasible. In current report Optical Coherence Tomography (OCT) in conjunction with optical clearing is applied for assessment of deep cartilage layers and cartilage-bone interface. The solution of Iohexol in water has been used as an optical clearing agent. The cartilage-bone boundary becomes ...
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    4. Glucose sensing in flowing blood and Intralipid by laser pulse time-of-flight and optical coherence tomography techniques

      Glucose sensing in flowing blood and Intralipid by laser pulse time-of-flight and optical coherence tomography techniques
      In this paper, we compare the sensitivities of the two optical modalities, laser pulse time-of-flight (TOF) and optical coherence tomography (OCT), in regard to glucose sensing within the range of 0-1000 mg/dl in flowing blood and tissue-mimicking liquid (Intralipid). We show that TOF technique is about twice more sensitive than OCT, as well for blood as for Intralipid measurements. In case of TOF technique, glucose sensitivity in Intralipid is ...
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    5. Detecting glucose-induced changes in in vitro and in vivo experiments with optical coherence tomography.

      Related Articles Detecting glucose-induced changes in in vitro and in vivo experiments with optical coherence tomography. J Biomed Opt. 2008 Mar-Apr;13(2):021111 Authors: Kinnunen M, Myllylä R, Vainio S Optical clearing is a well-known phenomenon. It is based on the matching of refractive indices of a bulk material and scattering particles. The same principle is also used in scattering-based optical measurements of different constituents, such as glucose. By ...
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    6. Application of optical coherence tomography, pulsed photoacoustic technique, and time-of-flight technique to detect changes in the scattering properties of a tissue-simulating phantom

      ...Matti Kinnunen and Risto Myllyla Intralipid is a well-known emulsion used as a tissue-simulating phantom in developing optical imaging and diagnostic techniques for medical applications. The optical coherence ...
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    7. Comparison of optical coherence tomography, the pulsed photoacoustic technique, and the time-of-flight technique in glucose measurements in vitro (Thesis)

      Comparison of optical coherence tomography, the pulsed photoacoustic technique, and the time-of-flight technique in glucose measurements in vitro (Thesis)
      The development of a non-invasive glucose monitoring technique is very important because it would tremendously diminish the need to puncture the skin when taking blood samples and help diabetic patients in controlling their blood glucose levels and in treating Diabetes Mellitus. The focus of this thesis is on measuring the effect of glucose on the light scattering properties of a tissue-simulating phantom and biological tissues in vitro. Optical coherence tomography ...
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  2. About Matti Kinnunen

    Matti Kinnunen is a Senior Technical Assistant at the University of Oulu, Optoelectronics and Measurement Techniques Laboratory and Infotech Oulu.