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    1. Mentioned In 517 Articles

    2. AN AUTOMATIC, INTERCAPILLARY AREA-BASED ALGORITHM FOR QUANTIFYING DIABETES-RELATED CAPILLARY DROPOUT USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Explore LWW Online Ophthalmology
      AN AUTOMATIC, INTERCAPILLARY AREA-BASED ALGORITHM FOR QUANTIFYING DIABETES-RELATED CAPILLARY DROPOUT USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To develop a robust, sensitive, and fully automatic algorithm to quantify diabetes-related capillary dropout using optical coherence tomography (OCT) angiography (OCTA). Methods: A 1,050-nm wavelength, 400 kHz A-scan rate swept-source optical coherence tomography prototype was used to perform volumetric optical coherence tomography angiography imaging over 3 mm x 3 mm fields in normal controls (n = 5), patients with diabetes without diabetic retinopathy (DR) (n = 7), patients with nonproliferative ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Jay S. Duker

    3. OSA Centennial Snapshots: OCT and the Flowering of Biophotonics

      Explore OSA | OSA Publishing
      OSA Centennial Snapshots: OCT and the Flowering of Biophotonics
      The birth, commercialization and ultimate impact of OCT stand out as landmark accomplishments even amid the abundant advances in biophotonics during the 1980s and 1990s. Twenty-five years ago this month, the editors of Science accepted for publication a research paper titled Optical Coherence Tomography. That three-word phrase (and its punchier abbreviation, OCT) heralded a revolution in ophthalmologyone that would spawn a billion-dollar-a-year market, and affect millions of people.
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      Mentions: Adolf F. Fercher Massachusetts Institute of Technology James G. Fujimoto

    4. Visualizing the Choriocapillaris Under Drusen: Comparing 1050-nm Swept-Source Versus 840-nm Spectral-Domain Optical Coherence Tomography Angiography

      Explore IOVS Journal Ophthalmology
      Visualizing the Choriocapillaris Under Drusen: Comparing 1050-nm Swept-Source Versus 840-nm Spectral-Domain Optical Coherence Tomography Angiography
      Purpose : To investigate the appearance of choriocapillaris (CC) flow under drusen by comparing long-wavelength (1050 nm) swept-source optical coherence tomography (SS-OCT) angiography with shorter-wavelength (840 nm) spectral-domain (SD) OCT angiography. Methods : Patients with drusen imaged on both devices on the same day were selected and graded. Ambiguous OCT angiography (OCTA) signal loss was defined as low OCTA signal on the en face OCTA CC image that also had low OCT ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Duke University

    5. ULTRAHIGH SPEED SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF RETINAL AND CHORIOCAPILLARIS ALTERATIONS IN DIABETIC PATIENTS WITH AND WITHOUT RETINOPATHY

      Explore LWW Online Ophthalmology
      ULTRAHIGH SPEED SWEPT SOURCE OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF RETINAL AND CHORIOCAPILLARIS ALTERATIONS IN DIABETIC PATIENTS WITH AND WITHOUT RETINOPATHY
      Purpose: To investigate the utility of ultrahigh speed, swept source optical coherence tomography angiography in visualizing retinal microvascular and choriocapillaris (CC) changes in diabetic patients. Methods: The study was prospective and cross-sectional. A 1,050 nm wavelength, 400 kHz A-scan rate swept source optical coherence tomography prototype was used to perform volumetric optical coherence tomography angiography of the retinal and CC vasculatures in diabetic patients and normal subjects. Sixty-three eyes ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Jay S. Duker

    6. Choroidal Neovascularization Analyzed on Ultrahigh-Speed Swept-Source Optical Coherence Tomography Angiography Compared to Spectral-Domain Optical Coherence Tomography Angiography

      Explore Elsevier Health Ophthalmology
      Choroidal Neovascularization Analyzed on Ultrahigh-Speed Swept-Source Optical Coherence Tomography Angiography Compared to Spectral-Domain Optical Coherence Tomography Angiography
      Purpose To compare visualization of choroidal neovascularization (CNV) secondary to age-related macular degeneration (AMD) using an ultrahigh-speed swept-source (SS) optical coherence tomography angiography (OCTA) prototype vs a spectral-domain (SD) OCTA device. Design Comparative analysis of diagnostic instruments. Methods Patients were prospectively recruited to be imaged on SD OCT and SS OCT devices on the same day. The SD OCT device employed is the RTVue Avanti (Optovue, Inc, Fremont, California, USA ...
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      Mentions: Universidade Federal de São Paulo Massachusetts Institute of Technology James G. Fujimoto

    8. Diagnosis and Follow-Up of Nonexudative Choroidal Neovascularization With Multiple Optical Coherence Tomography Angiography Devices: A Case Report

      Explore Healio.com Ophthalmology
      Diagnosis and Follow-Up of Nonexudative Choroidal Neovascularization With Multiple Optical Coherence Tomography Angiography Devices: A Case Report
      Nonexudative choroidal neovascularization (CNV) is a new phenomenon that has only recently been described in the literature with the advent of optical coherence tomography angiography (OCTA) imaging. The authors present a 1-year longitudinal follow-up of a nonexudative CNV lesion secondary to age-related macular degeneration. This report describes the appearance of the lesion on two commercially available spectral-domain OCTA devices and one prototype swept-source OCTA device. Management of these cases is ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Tufts University

    9. Foreword: 25 Years of Optical Coherence Tomography

      Explore IOVS Journal Ophthalmology
      Foreword: 25 Years of Optical Coherence Tomography
      This special issue commemorates the 25th anniversary of the development of optical coherence tomography (OCT). OCT has had a transformative impact in the field of ophthalmology and vision research, contributing to fundamental understanding of disease pathogenesis, drug discovery and development, and everyday clinical decision making in all ophthalmic subspecialties. The role of OCT in research and clinical care continues to accelerate, as judged by the cumulative number of publications in ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto David Huang

    10. The Development, Commercialization, and Impact of Optical Coherence Tomography

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      The Development, Commercialization, and Impact of Optical Coherence Tomography
      This review was written for the special issue of IOVS to describe the history of optical coherence tomography (OCT) and its evolution from a nonscientific, historic perspective. Optical coherence tomography has become a standard of care in ophthalmology, providing real-time information on structure and function diagnosing disease, evaluating progression, and assessing response to therapy, as well as helping to understand disease pathogenesis and create new therapies. Optical coherence tomography also ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Eric A. Swanson

    11. A Comparison Between Optical Coherence Tomography Angiography and Fluorescein Angiography for the Imaging of Type 1 Neovascularization

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      A Comparison Between Optical Coherence Tomography Angiography and Fluorescein Angiography for the Imaging of Type 1 Neovascularization
      Purpose : To determine the sensitivity of the combination of optical coherence tomography angiography (OCTA) and structural optical coherence tomography (OCT) for detecting type 1 neovascularization (NV) and to determine significant factors that preclude visualization of type 1 NV using OCTA. Methods : Multicenter, retrospective cohort study of 115 eyes from 100 patients with type 1 NV. A retrospective review of fluorescein (FA), OCT, and OCTA imaging was performed on a consecutive ...
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      Mentions: Massachusetts Institute of Technology Jay S. Duker LuEsther T. Mertz Retinal Research Center

    13. In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography

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      In vivo label-free measurement of lymph flow velocity and volumetric flow rates using Doppler optical coherence tomography
      Direct in vivo imaging of lymph flow is key to understanding lymphatic system function in normal and disease states. Optical microscopy techniques provide the resolution required for these measurements, but existing optical techniques for measuring lymph flow require complex protocols and provide limited temporal resolution. Here, we describe a Doppler optical coherence tomography platform that allows direct, label-free quantification of lymph velocity and volumetric flow rates. We overcome the challenge ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    14. Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Circumferential optical coherence tomography angiography imaging of the swine esophagus using a micromotor balloon catheter
      We demonstrate a micromotor balloon imaging catheter for ultrahigh speed endoscopic optical coherence tomography (OCT) which provides wide area, circumferential structural and angiographic imaging of the esophagus without contrast agents. Using a 1310 nm MEMS tunable wavelength swept VCSEL light source, the system has a 1.2 MHz A-scan rate and ~8.5 m axial resolution in tissue. The micromotor balloon catheter enables circumferential imaging of the esophagus at 240 ...
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      Mentions: Brigham and Women’s Hospital Massachusetts Institute of Technology James G. Fujimoto

    15. An Elastic Second Skin

      Explore Nature Publishing Group Dermatology
      An Elastic Second Skin
      We report the synthesis and application of an elastic, wearable crosslinked polymer layer (XPL) that mimics the properties of normal, youthful skin. XPL is made of a tunable polysiloxane-based material that can be engineered with specific elasticity, contractility, adhesion, tensile strength and occlusivity. XPL can be topically applied, rapidly curing at the skin interface without the need for heat- or light-mediated activation. In a pilot human study, we examined the ...
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      Mentions: Massachusetts Institute of Technology Massachusetts General Hospital Harvard University

    16. Massachusetts Institute of Technology Receives Grant for Optical Biopsy Using Optical Coherence Tomography

      Explore Optical Coherence Tomography News Gastroenterology , Funding
      Massachusetts Institute of Technology Receives Grant for Optical Biopsy Using Optical Coherence Tomography
      ...ow is a summary of the proposed work. This is a multidisciplinary collaboration between investigators at the Massachusetts Institute of Technology and the VA Boston Healthcare System integrating imaging technology resea...
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      Mentions: Massachusetts Institute of Technology National Institutes of Health James G. Fujimoto
    17. 1-15 of 517 1 2 3 4 ... 33 34 35 »
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  4. About Massachusetts Institute of Technology

    Massachusetts Institute of Technology

    Massachusetts Institute of Technology (MIT) is a private, coeducational research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing 32 academic departments, with a strong emphasis in theoretical, applied, and interdisciplinary scientific and technological research.  Laser Medicine and Medical Imaging Group at MIT.  The RLE Laser Medicine and Medical Imaging Group and its close collaborators were the originators of optical coherence tomography (OCT), a diagnostic technology now used in a growing number of medical fields. The group currently works to further understand and exploit the capabilities of OCT technology, with ongoing investigations in topics related to optical coherence microscopy development and optical biopsy using OCT.

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