1. Massachusetts Institute of Technology

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    1. Mentioned In 568 Articles

    2. A Quantum Field Approach for Advancing Optical Coherence Tomography Part I: First Order Correlations, Single Photon Interference, and Quantum Noise

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      A Quantum Field Approach for Advancing Optical Coherence Tomography Part I: First Order Correlations, Single Photon Interference, and Quantum Noise
      Optical coherence tomography has become an important imaging technology in cardiology and ophthalmology, with other applications under investigations. Major advances in optical coherence tomography (OCT) imaging are likely to occur through a quantum field approach to the technology. In this paper, which is the first part in a series on the topic, the quantum basis of OCT first order correlations is expressed in terms of full field quantization. Specifically first ...
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      Mentions: Brigham and Women’s Hospital Massachusetts Institute of Technology Mark E. Brezinski

    4. Robust wavenumber and dispersion calibration for Fourier-domain optical coherence tomography

      Explore OSA | OSA Publishing
      Robust wavenumber and dispersion calibration for Fourier-domain optical coherence tomography
      Many Fourier-domain optical coherence tomography (FD-OCT) systems sample the interference fringes with a non-uniform wavenumber ( k ) interval, introducing a chirp to the signal that depends on the path length difference underlying each fringe. A dispersion imbalance between sample and reference arms also generates a chirp in the fringe signal which, in contrast, is independent of depth. Fringe interpolation to obtain a signal linear in k and compensate dispersion imbalance is ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    5. Polymeric endovascular strut and lumen detection algorithm for intracoronary optical coherence tomography images

      Explore SPIE Digital Library Cardiology
      Polymeric endovascular strut and lumen detection algorithm for intracoronary optical coherence tomography images
      Polymeric endovascular implants are the next step in minimally invasive vascular interventions. As an alternative to traditional metallic drug-eluting stents, these often-erodible scaffolds present opportunities and challenges for patients and clinicians. Theoretically, as they resorb and are absorbed over time, they obviate the long-term complications of permanent implants, but in the short-term visualization and therefore positioning is problematic. Polymeric scaffolds can only be fully imaged using optical coherence tomography (OCT ...
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      Mentions: Massachusetts Institute of Technology California Institute of Technology

    7. A Joint Probabilistic Model for Speckle Variance, Amplitude Decorrelation and Interframe Variance (IFV) Optical Coherence Tomography Angiography

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      A Joint Probabilistic Model for Speckle Variance, Amplitude Decorrelation and Interframe Variance (IFV) Optical Coherence Tomography Angiography
      Optical Coherence Tomography Angiography (OCTA) is a general method to visualize blood flow in biological tissue. Despite its good results in practice, the commonly used Amplitude Decorrelation OCTA (AD-OCTA) measure suffers from a well-understood objective function, which makes it challenging to mathematically model post processing tasks like, e.g., denoising. In this paper, a probabilistic model is developed for the three OCTA measures Speckle Variance OCTA, ADOCTA and the newly ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Tufts University

    8. Microscope-Integrated Intraoperative Ultrahigh-Speed Swept-Source Optical Coherence Tomography for Widefield Retinal and Anterior Segment Imaging

      Explore Healio.com Ophthalmology
      Microscope-Integrated Intraoperative Ultrahigh-Speed Swept-Source Optical Coherence Tomography for Widefield Retinal and Anterior Segment Imaging
      ...the cover slip was 84%. The study was approved by the Tufts Medical Center institutional review board and the Massachusetts Institute of Technology Committee on the Use of Humans as Experimental Subjects. The research pr...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    9. Temporal and Volumetric Denoising via Quantile Sparse Image (QuaSI) Prior in Optical Coherence Tomography and Beyond

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      Temporal and Volumetric Denoising via Quantile Sparse Image (QuaSI) Prior in Optical Coherence Tomography and Beyond
      This paper introduces an universal and structure-preserving regularization term, called quantile sparse image (QuaSI) prior. The prior is suitable for denoising images from various medical image modalities. We demonstrate its effectivness on volumetric optical coherence tomography (OCT) and computed tomography (CT) data, which show differnt noise and image characteristics. OCT offers high-resolution scans of the human retina but is inherently impaired by speckle noise. CT on the other hand has ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto University of Erlangen

    10. Radiometric model for coaxial single- and multimode optical emission from double-clad fiber

      Explore OSA | OSA Publishing
      Radiometric model for coaxial single- and multimode optical emission from double-clad fiber
      Double-clad fibers (DCFs) are versatile waveguides supporting a single-mode core surrounded by a multimode inner cladding. DCFs are increasingly used for multimodal biomedical applications, such as imaging or therapy, for which the core is typically used for coherent illumination and the inner cladding, to support a concurrent modality. Proper optimization is, however, critical to ensure high optical performance and requires accurate modeling of coaxial single- and multimode output beams. In ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    12. Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University

      Explore Optical Coherence Tomography News Jobs & Studentships
      Post-doctoral Associate Position in Biophotonics / Biomedical Optical Imaging at Lehigh University
      ...In August 2007, Dr. Zhou joined Professor James G. Fujimoto’s Laser Medicine and Medical Imaging Group at the Massachusetts Institute of Technology (MIT) as a postdoctoral associate. Since then, he has been working on th...
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      Mentions: Massachusetts Institute of Technology National Institutes of Health James G. Fujimoto

    13. Cycloid scanning for wide field optical coherence tomography endomicroscopy and angiography in vivo

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Cycloid scanning for wide field optical coherence tomography endomicroscopy and angiography in vivo
      Devices that perform wide field-of-view (FOV) precision optical scanning are important for endoscopic assessment and diagnosis of luminal organ disease such as in gastroenterology. Optical scanning for in vivo endoscopic imaging has traditionally relied on one or more proximal mechanical actuators, limiting scan accuracy and imaging speed. There is a need for rapid and precise two-dimensional (2D) microscanning technologies to enable the translation of benchtop scanning microscopies to in vivo ...
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      Mentions: Johns Hopkins University Massachusetts Institute of Technology James G. Fujimoto

    14. Complex differential variance angiography with noise-bias correction for optical coherence tomography of the retina

      Explore OSA | OSA Publishing Ophthalmology
      Complex differential variance angiography with noise-bias correction for optical coherence tomography of the retina
      Complex differential variance (CDV) provides phase-sensitive angiographic imaging for optical coherence tomography (OCT) with immunity to phase-instabilities of the imaging system and small-scale axial bulk motion. However, like all angiographic methods, measurement noise can result in erroneous indications of blood flow that confuse the interpretation of angiographic images. In this paper, a modified CDV algorithm that corrects for this noise-bias is presented. This is achieved by normalizing the CDV signal ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Heidelberg Engineering

    15. Ultrahigh-speed endoscopic optical coherence tomography and angiography enables delineation of lateral margins of endoscopic mucosal resection: a case report

      Explore SAGE Journals Gastroenterology
      Ultrahigh-speed endoscopic optical coherence tomography and angiography enables delineation of lateral margins of endoscopic mucosal resection: a case report
      Endoscopic mucosal resection (EMR) is a common technique for resecting dysplastic lesions in Barretts esophagus (BE), stomach, and colon, 1 but precise delineation of dysplastic margins before resection and verification of complete removal after resection remain challenging. 2 , 3 Endoscopic optical coherence tomography (OCT) enables three-dimensional visualization of tissue microstructure and is commercially available as Volumetric Laser Endomicroscopy (NinePoint Medical, Bedford, MA, USA). 4 , 5 We recently developed an ultrahigh-speed ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    16. Optimized computer-aided segmentation and 3D reconstruction using intracoronary optical coherence tomography

      Explore IEEE Xplore Cardiology
      Optimized computer-aided segmentation and 3D reconstruction using intracoronary optical coherence tomography
      We present a novel and time-efficient method for intracoronary lumen detection which produces three-dimensional (3D) coronary arteries using Optical Coherence Tomographic (OCT) images. OCT images are acquired for multiple patients and longitudinal cross-section (LOCS) images are reconstructed using different acquisition angles. The lumen contours for each LOCS image are extracted and translated to 2D cross-sectional images. Using two angiographic projections the centerline of the coronary vessel is reconstructed in 3D ...
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      Mentions: Massachusetts Institute of Technology University of São Paulo
    17. 1-15 of 568 1 2 3 4 ... 36 37 38 »
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  4. About Massachusetts Institute of Technology

    Massachusetts Institute of Technology

    Massachusetts Institute of Technology (MIT) is a private, coeducational research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing 32 academic departments, with a strong emphasis in theoretical, applied, and interdisciplinary scientific and technological research.  Laser Medicine and Medical Imaging Group at MIT.  The RLE Laser Medicine and Medical Imaging Group and its close collaborators were the originators of optical coherence tomography (OCT), a diagnostic technology now used in a growing number of medical fields. The group currently works to further understand and exploit the capabilities of OCT technology, with ongoing investigations in topics related to optical coherence microscopy development and optical biopsy using OCT.

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