1. Massachusetts Institute of Technology

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    1. Mentioned In 544 Articles

    2. Development and translation of label-free functional microscopy based on optical coherence tomography (Thesis)

      Development and translation of label-free functional microscopy based on optical coherence tomography (Thesis)
      Optical coherence tomography (OCT), an imaging modality based on low coherence interferometry, can be extended to obtain various endogenous functional contrasts. This thesis focuses on the development and translation of angiographic and polarization sensitive (PS) OCT techniques for clinical and preclinical applications. This goal includes four specific aims. The first aim is to develop a clinical imaging system to image the anatomy and microvasculature of human skin. The second aim ...
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    3. Massachusetts Institute of Technology Receives NIH Grant for Optical Biopsy Using Optical Coherence Tomography

      Massachusetts Institute of Technology Receives  NIH Grant for Optical Biopsy Using Optical Coherence Tomography
      ...k.

      This is a multidisciplinary collaboration between investigators at the Massachusetts Institute of Technology and the VA Boston Healthcare System integrating imaging technology resea...

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    4. Finalists for the European Inventor Award 2017

      Finalists for the European Inventor Award 2017
      The European Patent Office (EPO) today announced that the team of U.S. Engineers James G. Fujimoto and Eric A. Swanson, and German Physicist Robert Huber, have been named finalists for the European Inventor Award 2017 in the category of Non-European countries" for medical imaging with optical coherence tomography (OCT). The winners of the 12th edition of the EPOs annual innovation prize will be announced at a ceremony held on ...
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    5. MIT Receives a 2017 NIH Grant for Novel Diagnostics with Optical Coherence Tomography

      MIT Receives a 2017 NIH Grant for Novel Diagnostics with Optical Coherence Tomography
      ...submission of a competing renewal application for an ongoing collaborative program among investigators at the Massachusetts Institute of Technology, New England Eye Center and University of Pittsburgh Medical Center Eye ...
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    6. QuaSI: Quantile Sparse Image Prior for Spatio-Temporal Denoising of Retinal OCT Data

      QuaSI: Quantile Sparse Image Prior for Spatio-Temporal Denoising of Retinal OCT Data
      Optical coherence tomography (OCT) enables high-resolution and non-invasive 3D imaging of the human retina but is inherently impaired by speckle noise. This paper introduces a spatio-temporal denoising algorithm for OCT data on a B-scan level using a novel quantile sparse image (QuaSI) prior. To remove speckle noise while preserving image structures of diagnostic relevance, we implement our QuaSI prior via median filter regularization coupled with a Huber data fidelity model ...
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    7. Integrated Local Binary Pattern Texture Features for Classification of Breast Tissue Imaged by Optical Coherence Microscopy

      Integrated Local Binary Pattern Texture Features for Classification of Breast Tissue Imaged by Optical Coherence Microscopy
      This paper proposes a texture analysis technique that can effectively classify different types of human breast tissue imaged by Optical Coherence Microscopy (OCM). OCM is an emerging imaging modality for rapid tissue screening and has the potential to provide high resolution microscopic images that approach those of histology. OCM images, acquired without tissue staining, however, pose unique challenges to image analysis and pattern classification. We examined multiple types of texture ...
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    8. Telecom tech continues to advance OCT

      Telecom tech continues to advance OCT
      Keep your ear to the ground for an increase in the repurposing for bio applications of technologies designed for non-bio applications, including telecom and automotive. Telecom we've already seenand are continuing to see. Optical coherence tomography ( OCT ) is a good example: This technique, which has substantially impacted ophthalmology and is emerging for many other applications, was enabled by technology developed decades ago for telecommunications. OCT generates volume images at ...
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    9. Fully automated lumen segmentation of intracoronary optical coherence tomography images

      Fully automated lumen segmentation of intracoronary optical coherence tomography images
      Optical coherence tomography (OCT) provides high-resolution cross-sectional images of arterial luminal morphology. Traditionally lumen segmentation of OCT images is performed manually by expert observers; a laborious, time consuming effort, sensitive to inter-observer variability process. Although several automated methods have been developed, the majority cannot be applied in real time because of processing demands. To address these limitations we propose a new method for rapid image segmentation of arterial lumen borders ...
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    10. The ecosystem that powered the translation of OCT from fundamental research to clinical and commercial impact [Invited]

      The ecosystem that powered the translation of OCT from fundamental research to clinical and commercial impact [Invited]
      25 years is a relatively short period of time for a medical technology to become a standard of care impacting the treatment of millions of people every year. Yet 25 years ago there were no OCT companies, no OCT products, no OCT markets, and only one journal article published using the term OCT (optical coherence tomography). OCT has had a tremendous scientific, clinical, and economic impact on society. Today, it ...
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    11. Endoscopic optical coherence tomography angiography microvascular features associated with dysplasia in Barrett's esophagus: a pilot study (with video)

      Endoscopic optical coherence tomography angiography microvascular features associated with dysplasia in Barrett's esophagus: a pilot study (with video)
      Background and Aims Angiogenesis is associated with neoplastic progression of Barretts esophagus (BE). Volumetric optical coherence tomography angiography (OCTA) visualizes subsurface microvasculature without exogenous contrast agents. We investigated the association of OCTA microvascular features with low-grade dysplasia (LGD) and high-grade dysplasia (HGD). Methods Fifty-two patients undergoing BE surveillance or endoscopic eradication therapies for dysplasia were imaged using volumetric OCTA and corresponding histological diagnoses obtained, to yield 97 data sets (non-dysplastic ...
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    12. Beth Isreal Deaconess Medical Center Receives Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology

      Beth Isreal Deaconess Medical Center Receives Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology
      ...esign — Dr. Gary Tearney (MGH), Dr. Peter Libby (Brigham and Women's Hospital), and Dr. Elazer Edelman (Massachusetts Institute of Technology) — and will help guide him scientifically and in his career develo...
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    13. "Nobel prize for engineering sciences" goes to MedUni Vienna researchers

      "Nobel prize for engineering sciences" goes to MedUni Vienna researchers
      Christoph Hitzenberger and Adolf Fercher from MedUni Vienna have been awarded this years Fritz J. and Dolores H. Russ Prize. The prize is awarded by the United States National Academy of Engineering (NAE) for technological developments that "have had a significant impact on society and have helped to improve human well-being". The two researchers from Vienna played a major role in the development of Optical Coherence Tomography (OCT), an examination ...
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    14. Eric Swanson Named 2017 IEEE Fellow for Contributions to Optical Coherence Tomography and Leadership in Optical Networking

      Eric Swanson Named 2017 IEEE Fellow for Contributions to Optical Coherence Tomography and Leadership in Optical Networking
      ...al Engineering from the University of Massachusetts at Amherst and an M.S. in Electrical Engineering from the Massachusetts Institute of Technology. The IEEE is the world’s leading professional association for advancing...
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  2. About Massachusetts Institute of Technology

    Massachusetts Institute of Technology

    Massachusetts Institute of Technology (MIT) is a private, coeducational research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing 32 academic departments, with a strong emphasis in theoretical, applied, and interdisciplinary scientific and technological research.  Laser Medicine and Medical Imaging Group at MIT.  The RLE Laser Medicine and Medical Imaging Group and its close collaborators were the originators of optical coherence tomography (OCT), a diagnostic technology now used in a growing number of medical fields. The group currently works to further understand and exploit the capabilities of OCT technology, with ongoing investigations in topics related to optical coherence microscopy development and optical biopsy using OCT.