1. Massachusetts Institute of Technology

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    1. Mentioned In 436 Articles

    2. All-fiber wavelength swept ring laser based on Fabry-Perot filter for optical frequency domain imaging

      All-fiber wavelength swept ring laser based on  Fabry-Perot filter for optical frequency domain  imaging

      Innovations in laser engineering have yielded several novel configurations for high repetition rate, broad sweep range, and long coherence length wavelength swept lasers. Although these lasers have enabled high performance frequency-domain optical coherence tomography, they are typically complicated and costly and many require access to proprietary materials or devices. Here, we demonstrate a simplified ring resonator configuration that is straightforward to construct from readily available materials at a low total cost. It was enabled by an insight regarding the significance of isolation against bidirectional operation and by configuring the sweep range of the intracavity filter to exceed its free spectral ...

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    3. Longitudinal necrotic shafts near TCFAs—A potential novel mechanism for plaque rupture to trigger ACS?

      Longitudinal necrotic shafts near TCFAs—A potential novel mechanism for plaque rupture to trigger ACS?
      ...Harvard Medical School, 25 Shattuck Street, Boston, MA 02115, USA * Department of Electrical Engineering, Massachusetts Institute of Technology, 77 MA Avenue, Cambridge, MA 02139, USA Correspondence * Correspondi...
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    4. Praevium Research Receives NIH Grant for VCSEL Technology for Ultrahigh Speed OCT Retinal and Anterior Eye Imaging.

      Praevium Research Receives NIH Grant for VCSEL Technology for Ultrahigh Speed OCT Retinal and Anterior Eye Imaging.
      ...ically pumped VCSELs for OCT at both 1310nm and 1050nm obtained by Praevium Research and collaborators at the Massachusetts Institute of Technology (MIT). This prior work has demonstrated numerous performance advantages ...
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    5. Quantitative technique for robust and noise-tolerant speed measurements based on speckle decorrelation in optical coherence tomography

      Quantitative technique for robust and noise-tolerant speed measurements based on speckle decorrelation in optical coherence tomography

      Intensity-based techniques in optical coherence tomography (OCT), such as those based on speckle decorrelation, have attracted great interest for biomedical and industrial applications requiring speed or flow information. In this work we present a rigorous analysis of the effects of noise on speckle decorrelation, demonstrate that these effects frustrate accurate speed quantitation, and propose new techniques that achieve quantitative and repeatable measurements. First, we derive the effect of background noise on the speckle autocorrelation function, finding two detrimental effects of noise. We propose a new autocorrelation function that is immune to the main effect of background noise and permits quantitative ...

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    6. Clinical Guide to Angio-OCT (Non Invasive, Dyeless OCT Angiography) (Textbook)

      Clinical Guide to Angio-OCT (Non Invasive, Dyeless OCT Angiography)  (Textbook)

      The book discusses the clinical possibilities of Angio-OCT. Most imaging in the book (77 figures in Chapters 5, 7.1 and 10) has been performed with XR-Avanti Optovue SD-OCT device using SSADA algorithm. A few figures in chapters 3, 7.2 and 8 have been performed with a swept source OCT prototype using SSADA algorithm. Another technique is described in chapter 11, using ultrahigh speed, SS-OCT and its applications to optical coherence tomography-angiography (OCTA). Key Features Angio-OCT (Dyeless OCT Angiography) is a new TECHNOLOGY that gives already useful results, that can be applied to day-to-day clinical ophthalmology. Several different OCT ...

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    7. Spectral-Domain and Swept-Source OCT Imaging of Asteroid Hyalosis: A Case Report

      Spectral-Domain and Swept-Source OCT Imaging of Asteroid Hyalosis: A Case Report

      A 72-year-old man with diabetes was referred to the retina clinic for diabetic retinopathy. Detailed funduscopic examination of the left eye was limited by prominent asteroid hyalosis. Spectral-domain (SD) and swept-source (SS) optical coherence tomography (OCT) were utilized to examine the vitreous, vitreoretinal interface, and the morphology of the retina. Asteroid hyalosis induced artifacts of the OCT images, which resolved when the appropriate imaging protocols were applied. SS-OCT may show superior diagnostic and preoperative capabilities when compared to SD-OCT in the settings of asteroid hyalosis-induced media opacity.

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    8. Endothelial Shear Stress and Coronary Plaque Characteristics in Humans: A Combined Frequency-Domain Optical Coherence Tomography and Computational Fluid Dynamics Study

      Endothelial Shear Stress and Coronary Plaque Characteristics in Humans: A Combined Frequency-Domain Optical Coherence Tomography and Computational Fluid Dynamics Study
      .... ^4Department of Electrical Engineering and Computer Science, and Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, MA 5. ^5Biostatistics Center, Massachusetts General Hosp...
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    9. Optical Coherence Tomography in Coronary Artery Disease: Toward Sub cellular Imaging

      Optical Coherence Tomography in Coronary Artery  Disease: Toward Sub cellular Imaging

      Intracoronary optical coherence tomography (OCT) is an interferometric imaging technology that uses near-infrared light to provide cross-sectional images with an axial resolution of 10 μm and a transverse of 20-40 μm in vivo. The imaging capabilities of OCT have enabled visualization of important features of coronary plaque, including thrombus, macrophage, neovascularization, stent implantation and stent strut coverage, which have provided new insights for better understanding of this disease. Frequency domain (FD)-OCT is secondgeneration form of OCT that is able to acquire OCT images at a much higher frame. The high-speed imaging capabilities of FD-OCT have made intravascular OCT practical ...

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    10. Computer-Aided Image Analysis Algorithm to Enhance In Vivo Diagnosis of Plaque Erosion by Intravascular Optical Coherence Tomography

      Computer-Aided Image Analysis Algorithm to Enhance In Vivo Diagnosis of Plaque Erosion by Intravascular Optical Coherence Tomography
      ...g3* 1. ^1Research Laboratory of Electronics, Department of Electrical Engineering and Computer Science, Massachusetts Institute of Technology, Cambridge, MA 2. ^2Department of Cardiology, The Second Affiliated ...
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    11. MIT Receives NIH Grant for Optical Biopsy Using Optical Coherence Tomography

      MIT Receives NIH Grant for Optical Biopsy Using Optical Coherence Tomography
      ...ow is a summary of the proposed work. This is a multidisciplinary collaboration between investigators at the Massachusetts Institute of Technology and the VA Boston Healthcare System integrating imaging technology resea...
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    12. 1-15 of 436 1 2 3 4 ... 27 28 29 »
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  2. About Massachusetts Institute of Technology

    Massachusetts Institute of Technology

    Massachusetts Institute of Technology (MIT) is a private, coeducational research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing 32 academic departments, with a strong emphasis in theoretical, applied, and interdisciplinary scientific and technological research.  Laser Medicine and Medical Imaging Group at MIT.  The RLE Laser Medicine and Medical Imaging Group and its close collaborators were the originators of optical coherence tomography (OCT), a diagnostic technology now used in a growing number of medical fields. The group currently works to further understand and exploit the capabilities of OCT technology, with ongoing investigations in topics related to optical coherence microscopy development and optical biopsy using OCT.