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    1. Mentioned In 614 Articles

    2. Analyzing Relative Flow Speeds in Diabetic Retinopathy Using Variable Interscan Time Analysis Optical Coherence Tomography Angiography

      Explore ScienceDirect Ophthalmology
      Analyzing Relative Flow Speeds in Diabetic Retinopathy Using Variable Interscan Time Analysis Optical Coherence Tomography Angiography
      Objective Further insight into the flow characteristics of the vascular features associated with diabetic retinopathy (DR) may improve assessment and treatment of disease progression. The variable interscan time analysis (VISTA) algorithm is an extension of optical coherence tomography angiography (OCTA) that detects relative blood flow speeds which can then be depicted on a color-coded map. This study utilized VISTA to analyze relative blood flow speeds in the microvascular changes associated ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Andre J. Witkin

    3. Macular and Peripapillary OCTA Metrics Predict Progression in Diabetic Retinopathy: A Sub-analysis of TIME-2b Study Data

      Explore American Journal of Ophthalmology Ophthalmology
      Macular and Peripapillary OCTA Metrics Predict Progression in Diabetic Retinopathy: A Sub-analysis of TIME-2b Study Data
      Purpose To identify optical coherence tomography angiography (OCTA) derived vessel metrics of the macula and optic nerve head (ONH) that predict diabetic retinopathy (DR) disease progression. Design Secondary analysis of clinical trial data Methods This was a sub-analysis of prospectively collected data from 73 subjects that participated in the TIME-2b Study (Aerpio Pharmaceuticals), a multi-center clinical trial for patients with moderate to severe DR treated with AKB-9778 and followed over ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Optovue

    4. Tethered capsule en face optical coherence tomography for imaging Barrett’s esophagus in unsedated patients

      Explore arxiv.org Gastroenterology
      Tethered capsule en face optical coherence tomography for imaging Barrett’s esophagus in unsedated patients
      Objective Detection of Barretts esophagus (BE) at points of care outside the endoscopy suite may improve screening access and reduce esophageal adenocarcinoma mortality. Tethered capsule optical coherence tomography (OCT) can volumetrically image esophageal mucosa and detect BE in unsedated patients. We investigated ultrahigh-speed tethered capsule, swept-source OCT (SS-OCT) in unsedated patients, improved device design, developed procedural techniques, measured how capsule contact and longitudinal pullback non-uniformity affect coverage, and assessed patient ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Thorlabs

    5. Machine Leaning Model Comparison for Automatic Segmentation of Intracoronary Optical Coherence Tomography and Plaque Cap Thickness Quantification

      Explore Open Journal Systems Cardiology
      Machine Leaning Model Comparison for Automatic Segmentation of Intracoronary Optical Coherence Tomography and Plaque Cap Thickness Quantification
      Optical coherence tomography (OCT) is a new intravascular imaging technique with high resolution and could provide accurate morphological information for plaques in coronary arteries. However, its segmentation is still commonly performed manually by experts which is time consuming. The aim of this study was to develop automatic techniques to characterize plaque components and quantify plaque cap thickness using 3 machine learning methods including convolutional neural network (CNN) with U-Net architecture ...
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      Mentions: Massachusetts Institute of Technology Emory University Georgia Institute of Technology

    6. Correction propagation for user-assisted optical coherence tomography segmentation: general framework and application to Bruch’s membrane segmentation

      Explore OSA | OSA Publishing
      Correction propagation for user-assisted optical coherence tomography segmentation: general framework and application to Bruch’s membrane segmentation
      Optical coherence tomography (OCT) is a commonly used ophthalmic imaging modality. While OCT has traditionally been viewed cross-sectionally (i.e., as a sequence of B-scans), higher A-scan rates have increased interest in en face OCT visualization and analysis. The recent clinical introduction of OCT angiography (OCTA) has further spurred this interest, with chorioretinal OCTA being predominantly displayed via en face projections. Although en face visualization and quantitation are natural for ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Tufts University

    7. Imaging intracellular motion with dynamic micro-optical coherence tomography

      Explore OSA | OSA Publishing
      Imaging intracellular motion with dynamic micro-optical coherence tomography
      This paper describes a new technology that uses 1-m-resolution optical coherence tomography (OCT) to obtain cross-sectional images of intracellular dynamics with dramatically enhanced image contrast. This so-called dynamic OCT (d-OCT) is accomplished by acquiring a time series of OCT images and conducting power frequency analysis of the temporal fluctuations that arise from intracellular motion on a pixel-per-pixel basis. Here, we demonstrate d-OCT imaging of freshly excised human esophageal and cervical ...
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      Mentions: Guillermo J. Tearney Massachusetts Institute of Technology Massachusetts General Hospital

    8. Massachusetts Institute of Technology Receives NIH Grant for Novel Optical Diagnostics with Optical Coherence Tomography

      Explore Optical Coherence Tomography News Funding
      Massachusetts Institute of Technology Receives NIH Grant for Novel Optical Diagnostics with Optical Coherence Tomography
      ...ext-align: justify;">his proposal is a renewal of an ongoing collaborative program among investigators at the Massachusetts Institute of Technology (MIT) and New England Eye Center (NEEC). The program focuses on the deve...
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      Mentions: Massachusetts Institute of Technology National Institutes of Health James G. Fujimoto

    9. Topographic analysis of macular choriocapillaris flow deficits in diabetic retinopathy using swept–source optical coherence tomography angiography

      Explore journalretinavitreous.biomedcentral.com Ophthalmology
      Topographic analysis of macular choriocapillaris flow deficits in diabetic retinopathy using swept–source optical coherence tomography angiography
      Background The purpose of this study was to investigate the association between diabetic retinopathy (DR) severity and macular choriocapillaris (CC) flow deficit percentage (FD %) in different macular regions using swept-source optical coherence tomography angiography (SS-OCTA). Methods Diabetic patients with SS-OCTA images were graded by severity and retrospectively assessed. CC FD % was calculated in four different regions of the OCTA image: inner, middle, outer, and full-field region. The generalized estimating equations ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto Yale University

    10. Noise and bias in optical coherence tomography intensity signal decorrelation

      Explore OSA | OSA Publishing
      Noise and bias in optical coherence tomography intensity signal decorrelation
      Functional optical coherence tomography (OCT) imaging based on the decorrelation of the intensity signal has been used extensively in angiography and is finding use in flowmetry and therapy monitoring. In this work, we present a rigorous analysis of the autocorrelation function, introduce the concepts of contrast bias, statistical bias and variability, and identify the optimal definition of the second-order autocorrelation function (ACF) g (2) to improve its estimation from limited ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    11. Forward multiple scattering dominates speckle decorrelation in whole-blood flowmetry using optical coherence tomography

      Explore OSA | OSA Publishing
      Forward multiple scattering dominates speckle decorrelation in whole-blood flowmetry using optical coherence tomography
      Quantitative blood flow measurements using optical coherence tomography (OCT) have a wide potential range of medical research and clinical applications. Flowmetry based on the temporal dynamics of the OCT signal may have the ability to measure three-dimensional flow profiles regardless of the flow direction. State-of-the-art models describing the OCT signal temporal statistics are based on dynamic light scattering (DLS), a model which is inherently limited to single scattering regimes. DLS ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    12. Post-doctoral Associate Positions in Biophotonics / Biomedical Optical Imaging at Washington University in St. Louis

      Explore Optical Coherence Tomography News Jobs & Studentships
      Post-doctoral Associate Positions in Biophotonics / Biomedical Optical Imaging at Washington University in St. Louis
      ...h.  After graduation, he joined Professor James G. Fujimoto's Laser Medicine and Medical Imaging Group at the Massachusetts Institute of Technology (MIT) as a postdoctoral associate. In 2012, Dr. Zhou joined the faculty ...
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      Mentions: Massachusetts Institute of Technology National Institutes of Health James G. Fujimoto

    13. SPATIAL DISTRIBUTION OF CHORIOCAPILLARIS IMPAIRMENT IN EYES WITH CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Quantitative OCT Angiography Study

      Explore LWW Online Ophthalmology
      SPATIAL DISTRIBUTION OF CHORIOCAPILLARIS IMPAIRMENT IN EYES WITH CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Quantitative OCT Angiography Study
      ...ent response. *Department of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts; §Department of Ophthalmology, Bascom Palmer E...
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      Mentions: Philip J. Rosenfeld Massachusetts Institute of Technology James G. Fujimoto

    14. Compressed Sensing for Optical Coherence Tomography Angiography Volume Generation

      Explore Home - Springer Ophthalmology
      Compressed Sensing for Optical Coherence Tomography Angiography Volume Generation
      Optical coherence tomography angiography (OCTA) is an increasingly popular modality for imaging of the retinal vasculature. Repeated optical coherence tomography (OCT) scans of the retina allow the computation of motion contrast to display the retinal vasculature. To the best of our knowledge, we present the first application of compressed sensing for the generation of OCTA volumes. Using a probabilistic signal model for the computation of OCTA volumes and a 3D ...
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      Mentions: Massachusetts Institute of Technology James G. Fujimoto University of Erlangen

    15. Application and Evaluation of Highly Automated Software for Comprehensive Stent Analysis in Intravascular Optical Coherence Tomography

      Explore Nature Publishing Group Cardiology
      Application and Evaluation of Highly Automated Software for Comprehensive Stent Analysis in Intravascular Optical Coherence Tomography
      Intravascular optical coherence tomography (IVOCT) is used to assess stent tissue coverage and malapposition in stent evaluation trials. We developed the OCT Image Visualization and Analysis Toolkit for Stent (OCTivat-Stent), for highly automated analysis of IVOCT pullbacks. Algorithms automatically detected the guidewire, lumen boundary, and stent struts; determined the presence of tissue coverage for each strut; and estimated the stent contour for comparison of stent and lumen area. Strut-level tissue ...
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      Mentions: Massachusetts Institute of Technology Case Western Reserve University Zhao Wang

    16. Acucela Meets with NASA and TRISH for Phase 1 Update for SS-OCT Project

      Explore Optical Coherence Tomography News Ophthalmology , Other Business News
      Acucela Meets with NASA and TRISH for Phase 1 Update for SS-OCT Project
      ...academic consortium led by Baylor College of Medicine and includes the California Institute of Technology and Massachusetts Institute of Technology. The mission of TRISH is to lead a natural effort in translating cutting...
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      Mentions: Massachusetts Institute of Technology California Institute of Technology Baylor College of Medicine
    17. 1-15 of 614 1 2 3 4 ... 39 40 41 »
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  4. About Massachusetts Institute of Technology

    Massachusetts Institute of Technology

    Massachusetts Institute of Technology (MIT) is a private, coeducational research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing 32 academic departments, with a strong emphasis in theoretical, applied, and interdisciplinary scientific and technological research.  Laser Medicine and Medical Imaging Group at MIT.  The RLE Laser Medicine and Medical Imaging Group and its close collaborators were the originators of optical coherence tomography (OCT), a diagnostic technology now used in a growing number of medical fields. The group currently works to further understand and exploit the capabilities of OCT technology, with ongoing investigations in topics related to optical coherence microscopy development and optical biopsy using OCT.

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