1. Massachusetts Institute of Technology

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    1. Mentioned In 642 Articles

    2. Multiscale correlation of microvascular changes on optical coherence tomography angiography with retinal sensitivity in diabetic retinopathy

      Explore LWW Online Ophthalmology
      Multiscale correlation of microvascular changes on optical coherence tomography angiography with retinal sensitivity in diabetic retinopathy
      Purpose: To assess global, zonal, and local correlations between vessel density changes measured by optical coherence tomography angiography (OCTA) and retinal sensitivity measured by microperimetry across diabetic retinopathy severity. Methods: Diabetic patients and non-diabetic controls underwent OCTA imaging and microperimetry testing. Pearson's correlation was used to assess associations between average sensitivity and skeletonized vessel density (SVD) or FAZ area centrally. Linear mixed effects modeling was used to assess relationships ...
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      Mentions: Massachusetts Institute of Technology Tufts University

    3. Analysis of correlations between local geographic atrophy growth rates and local OCT angiography-measured choriocapillaris flow deficits

      Explore OSA | OSA Publishing Ophthalmology
      Analysis of correlations between local geographic atrophy growth rates and local OCT angiography-measured choriocapillaris flow deficits
      The purpose of this study is to quantitatively assess correlations between local geographic atrophy (GA) growth rates and local optical coherence tomography angiography (OCTA)-measured choriocapillaris (CC) flow deficits. Thirty-eight eyes from 27 patients with GA secondary to age-related macular degeneration (AMD) were imaged with a commercial 1050 nm swept-source OCTA instrument at 3 visits, each separated by 6 months. Pearson correlations were computed between local GA growth rates, estimated ...
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      Mentions: Massachusetts Institute of Technology University of Washington University of Miami

    4. Layer-based, depth-resolved computation of attenuation coefficients and backscattering fractions in tissue using optical coherence tomography

      Explore OSA | OSA Publishing
      Layer-based, depth-resolved computation of attenuation coefficients and backscattering fractions in tissue using optical coherence tomography
      Structural optical coherence tomography (OCT) images of tissue stand to benefit from greater functionalization and quantitative interpretation. The OCT attenuation coefficient , an analogue of the imaged samples scattering coefficient, offers potential functional contrast based on the relationship of to sub-resolution physical properties of the sample. Attenuation coefficients are computed either by fitting a representative over several depth-wise pixels of a samples intensity decay, or by using previously-developed depth-resolved attenuation algorithms ...
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      Mentions: Massachusetts Institute of Technology Massachusetts General Hospital Harvard University

    5. Massachusetts Institute of Technology Receives NIH Grant for Novel Optical Diagnostics with Optical Coherence Tomography

      Explore Optical Coherence Tomography News Funding
      Massachusetts Institute of Technology Receives NIH Grant for Novel Optical Diagnostics with Optical Coherence Tomography
      ...xt-align: justify;">This proposal is a renewal of an ongoing collaborative program among investigators at the Massachusetts Institute of Technology (MIT) and New England Eye Center (NEEC). The program focuses on the deve...
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      Mentions: Massachusetts Institute of Technology National Institutes of Health

    6. Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility

      Explore Nature Publishing Group Cardiology
      Three dimensional reconstruction of coronary artery stents from optical coherence tomography: experimental validation and clinical feasibility
      The structural morphology of coronary stents (e.g. stent expansion, lumen scaffolding, strut apposition, tissue protrusion, side branch jailing, strut fracture), and the local hemodynamic environment after stent deployment are key determinants of procedural success and subsequent clinical outcomes. High-resolution intracoronary imaging has the potential to enable the geometrically accurate three-dimensional (3D) reconstruction of coronary stents. The aim of this work was to present a novel algorithm for 3D stent ...
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      Mentions: Massachusetts Institute of Technology Emory University Mount Sinai School of Medicine

    7. Post-doctoral Associate Positions in Biophotonics at Washington University in St. Louis

      Explore Optical Coherence Tomography News Jobs & Studentships
      Post-doctoral Associate Positions in Biophotonics at Washington University in St. Louis
      ...sp; After graduation, he joined Professor James G. Fujimoto's Laser Medicine and Medical Imaging Group at the Massachusetts Institute of Technology (MIT) as a postdoctoral associate. In 2012, Dr. Zhou joined the faculty ...
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      Mentions: Massachusetts Institute of Technology National Institutes of Health Lehigh University

    9. Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural and angiographic imaging with miniaturized brushless motor probes
      Swept source optical coherence tomography (SS-OCT) enables volumetric imaging of subsurface structure. However, applications requiring wide fields of view (FOV), rapid imaging, and higher resolutions have been challenging because multi-MHz axial scan (A-scan) rates are needed. We describe a microelectromechanical systems vertical cavity surface-emitting laser (MEMS-VCSEL) SS-OCT technology for A-scan rates of 2.4 and 3.0 MHz. Sweep to sweep calibration and resampling are performed using dual channel acquisition ...
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      Mentions: Brigham and Women’s Hospital Massachusetts Institute of Technology Thorlabs

    10. Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural ...

      Explore OSA | OSA Publishing Gastroenterology , Probes , Tunable Sources
      Multi-MHz MEMS-VCSEL swept-source optical coherence tomography for endoscopic structural ...
      Swept source optical coherence tomography (SS-OCT) enables volumetric imaging of subsurface structure. However, applications requiring wide fields of view (FOV), rapid imaging, and higher resolutions have been challenging because multi-MHz axial scan (A-scan) rates are needed. We describe a microelectromechanical systems vertical cavity surface-emitting laser (MEMS-VCSEL) SS-OCT technology for A-scan rates of 2.4 and 3.0 MHz. Sweep to sweep calibration and resampling are performed using dual channel acquisition ...
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      Mentions: Massachusetts Institute of Technology National Institutes of Health Thorlabs

    12. Full Thickness Macular Hole Size by Hypertransmission Signal on Spectral-Domain Optical Coherence Tomography

      Explore LWW Online Ophthalmology
      Full Thickness Macular Hole Size by Hypertransmission Signal on Spectral-Domain Optical Coherence Tomography
      Purpose: To assess the full thickness macular hole (FTMH) size using the choroidal hypertransmission signal on spectral domain optical coherence tomography (SD-OCT), and to compare this method to the standard aperture measurement of the minimum aperture size at the level of the neurosensory retina. Design: Cross-sectional study of retrospective data. Methods: Eyes with FTMH imaged on SD-OCT were included. Two independent masked graders used the device's built-in caliper tool ...
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      Mentions: Massachusetts Institute of Technology Tufts University

    13. 3D Reconstruction of Coronary Artery Stents From Optical Coherence Tomography: Experimental Validation and Clinical Feasibility

      Explore Home | Research Square Cardiology
      3D Reconstruction of Coronary Artery Stents From Optical Coherence Tomography: Experimental Validation and Clinical Feasibility
      The structural morphology of stents (e.g. expansion, lumen scaffolding, strut apposition, tissue protrusion, side branch jailing, strut fracture), and the local hemodynamic environment after stent deployment in coronary arteries are key determinants of procedural success and subsequent clinical outcomes. High-resolution intracoronary imaging has the potential to enable the geometrically correct 3D reconstruction of coronary stents. The aim of this work was to present a novel algorithm for 3D stent ...
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      Mentions: Massachusetts Institute of Technology

    14. Deliberations of an International Panel of Experts on OCTA Nomenclature of nAMD

      Explore Ophthalmology Ophthalmology
      Deliberations of an International Panel of Experts on OCTA Nomenclature of nAMD
      A panel of imaging experts was assembled to review neovascular age-related macular degeneration optical coherence tomography angiography descriptors published to date, and test agreement on use of these terms, which was found to be low. Optical coherence tomography angiography (OCTA) has been used to identify and characterize macular neovascularization (MNV) secondary to age-related macular degeneration (AMD). 1-4 Many studies have explored OCTA morphological features of MNV that might serve as ...
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      Mentions: Massachusetts Institute of Technology Medical University of Vienna Tufts University

    15. Efficient and high accuracy 3-D OCT angiography motion correction in pathology

      Explore OSA | OSA Publishing Ophthalmology
      Efficient and high accuracy 3-D OCT angiography motion correction in pathology
      We describe a novel method for non-rigid 3-D motion correction of orthogonally raster-scanned optical coherence tomography angiography volumes. This is the first approach that aligns predominantly axial structural features such as retinal layers as well as transverse angiographic vascular features in a joint optimization. Combined with orthogonal scanning and favorization of kinematically more plausible displacements, subpixel alignment and micrometer-scale distortion correction is achieved in all 3 dimensions. As no specific ...
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      Mentions: Massachusetts Institute of Technology Tufts University University of Erlangen

    16. Correction of circumferential and longitudinal motion distortion in high-speed catheter/endoscope-based optical coherence tomography

      Explore OSA | OSA Publishing Gastroenterology
      Correction of circumferential and longitudinal motion distortion in high-speed catheter/endoscope-based optical coherence tomography
      ... performed under an IRB protocol approved by VA Boston Healthcare System (VABHS), Harvard Medical School, and Massachusetts Institute of Technology. Written informed consent was obtained before imaging. Data was obtained...
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      Mentions: Massachusetts Institute of Technology Harvard University
    17. 1-15 of 642 1 2 3 4 ... 41 42 43 »
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  4. About Massachusetts Institute of Technology

    Massachusetts Institute of Technology

    Massachusetts Institute of Technology (MIT) is a private, coeducational research university located in Cambridge, Massachusetts. MIT has five schools and one college, containing 32 academic departments, with a strong emphasis in theoretical, applied, and interdisciplinary scientific and technological research.  Laser Medicine and Medical Imaging Group at MIT.  The RLE Laser Medicine and Medical Imaging Group and its close collaborators were the originators of optical coherence tomography (OCT), a diagnostic technology now used in a growing number of medical fields. The group currently works to further understand and exploit the capabilities of OCT technology, with ongoing investigations in topics related to optical coherence microscopy development and optical biopsy using OCT.

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