Articles that mention Massachusetts Institute of Technology -Optical Coherence Tomography News

Massachusetts Institute of Technology

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1. Mentioned In 607 Articles
2. Topographic analysis of macular choriocapillaris flow deficits in diabetic retinopathy using swept–source optical coherence tomography angiography
  
  Explore journalretinavitreous.biomedcentral.com Mar 24 2020 Ophthalmology
  
  Background The purpose of this study was to investigate the association between diabetic retinopathy (DR) severity and macular choriocapillaris (CC) flow deficit percentage (FD %) in different macular regions using swept-source optical coherence tomography angiography (SS-OCTA). Methods Diabetic patients with SS-OCTA images were graded by severity and retrospectively assessed. CC FD % was calculated in four different regions of the OCTA image: inner, middle, outer, and full-field region. The generalized estimating equations ...
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  Mentions: Massachusetts Institute of Technology James G. Fujimoto Yale University
3. Noise and bias in optical coherence tomography intensity signal decorrelation
  
  Explore OSA | OSA Publishing Mar 22 2020
  
  Functional optical coherence tomography (OCT) imaging based on the decorrelation of the intensity signal has been used extensively in angiography and is finding use in flowmetry and therapy monitoring. In this work, we present a rigorous analysis of the autocorrelation function, introduce the concepts of contrast bias, statistical bias and variability, and identify the optimal definition of the second-order autocorrelation function (ACF) g (2) to improve its estimation from limited ...
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  Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital
4. Forward multiple scattering dominates speckle decorrelation in whole-blood flowmetry using optical coherence tomography
  
  Explore OSA | OSA Publishing Mar 17 2020
  
  Quantitative blood flow measurements using optical coherence tomography (OCT) have a wide potential range of medical research and clinical applications. Flowmetry based on the temporal dynamics of the OCT signal may have the ability to measure three-dimensional flow profiles regardless of the flow direction. State-of-the-art models describing the OCT signal temporal statistics are based on dynamic light scattering (DLS), a model which is inherently limited to single scattering regimes. DLS ...
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  Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital
5. Post-doctoral Associate Positions in Biophotonics / Biomedical Optical Imaging at Washington University in St. Louis
  
  Explore Optical Coherence Tomography News Feb 26 2020 Jobs & Studentships
  
  ...h. After graduation, he joined Professor James G. Fujimoto's Laser Medicine and Medical Imaging Group at the Massachusetts Institute of Technology (MIT) as a postdoctoral associate. In 2012, Dr. Zhou joined the faculty ...
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  Mentions: Massachusetts Institute of Technology National Institutes of Health James G. Fujimoto
6. SPATIAL DISTRIBUTION OF CHORIOCAPILLARIS IMPAIRMENT IN EYES WITH CHOROIDAL NEOVASCULARIZATION SECONDARY TO AGE-RELATED MACULAR DEGENERATION: A Quantitative OCT Angiography Study
  
  Explore LWW Online Feb 21 2020 Ophthalmology
  
  ...ent response. *Department of Electrical Engineering and Computer Science, Research Laboratory of Electronics, Massachusetts Institute of Technology, Cambridge, Massachusetts; §Department of Ophthalmology, Bascom Palmer E...
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  Mentions: Philip J. Rosenfeld Massachusetts Institute of Technology James G. Fujimoto
7. Compressed Sensing for Optical Coherence Tomography Angiography Volume Generation
  
  Explore Home - Springer Feb 18 2020 Ophthalmology
  
  Optical coherence tomography angiography (OCTA) is an increasingly popular modality for imaging of the retinal vasculature. Repeated optical coherence tomography (OCT) scans of the retina allow the computation of motion contrast to display the retinal vasculature. To the best of our knowledge, we present the first application of compressed sensing for the generation of OCTA volumes. Using a probabilistic signal model for the computation of OCTA volumes and a 3D ...
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  Mentions: Massachusetts Institute of Technology James G. Fujimoto University of Erlangen
8. Application and Evaluation of Highly Automated Software for Comprehensive Stent Analysis in Intravascular Optical Coherence Tomography
  
  Explore Nature Publishing Group Feb 12 2020 Cardiology
  
  Intravascular optical coherence tomography (IVOCT) is used to assess stent tissue coverage and malapposition in stent evaluation trials. We developed the OCT Image Visualization and Analysis Toolkit for Stent (OCTivat-Stent), for highly automated analysis of IVOCT pullbacks. Algorithms automatically detected the guidewire, lumen boundary, and stent struts; determined the presence of tissue coverage for each strut; and estimated the stent contour for comparison of stent and lumen area. Strut-level tissue ...
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  Mentions: Massachusetts Institute of Technology Case Western Reserve University Zhao Wang
9. Acucela Meets with NASA and TRISH for Phase 1 Update for SS-OCT Project
  
  Explore Optical Coherence Tomography News Feb 3 2020 Ophthalmology , Other Business News
  
  ...academic consortium led by Baylor College of Medicine and includes the California Institute of Technology and Massachusetts Institute of Technology. The mission of TRISH is to lead a natural effort in translating cutting...
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  Mentions: Massachusetts Institute of Technology California Institute of Technology Baylor College of Medicine
10. Deep OCT Angiography Image Generation for Motion Artifact Suppression
  
  Explore arxiv.org Jan 14 2020 Ophthalmology
  
  Eye movements, blinking and other motion during the acquisition of optical coherence tomography (OCT) can lead to artifacts, when processed to OCT angiography (OCTA) images. Affected scans emerge as high intensity (white) or missing (black) regions, resulting in lost information. The aim of this research is to fill these gaps using a deep generative model for OCT to OCTA image translation relying on a single intact OCT scan. Therefore, a ...
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  Mentions: Massachusetts Institute of Technology James G. Fujimoto Siemens
11. Measuring coronary artery flow rates using intravascular optical coherence tomography to improve the assessment of percutaneous coronary intervention (Thesis)
  
  Explore DSpace@MIT Jan 14 2020 Cardiology , Student Theses
  
  In this project, a blood flow quantification technique was developed based on a novel backscattering indicator-dilution approach for intravascular optical coherence tomography (IV-OCT). It achieved the goal of obtaining the flow velocity in a coronary artery of interest by analyzing the backscattering signal from blood after passage of a bolus of Ringer's lactate or another transparent injectate, in parallel to thermodilution coronary flow reserve (CFR). In contrast to thermodilution ...
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  Mentions: Massachusetts Institute of Technology
12. Beth Israel Deaconess Medical Center Receives NIH Grant for Intravascular Molecular-Structural Imaging of Coronary Stent Pathobiology
  
  Explore Optical Coherence Tomography News Jan 7 2020 Cardiology , Funding
  
  ...tent design — Dr. Gary Tearney (MGH), Dr. Peter Libby (Brigham and Women's Hospital), and Dr. Elazer Edelman (Massachusetts Institute of Technology) — and will help guide him scientifically and in his career development ...
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  Mentions: Guillermo J. Tearney Beth Israel Deaconess Medical Center Massachusetts Institute of Technology
13. Application of Corneal Optical Coherence Tomography Angiography for Assessment of Vessel Depth in Corneal Neovascularization
  
  Explore LWW Online Dec 28 2019 Ophthalmology
  
  Purpose: To map and measure the depths of corneal neovascularization (NV) using 3-dimensional optical coherence tomography angiography (OCTA) at 2 different wavelengths. Methods: Corneal NV of varying severity, distribution, and underlying etiology was examined. Average NV depth and vessel density were measured using 840-nm spectral-domain OCTA and 1050-nm swept-source OCTA. The OCTA results were compared with clinical slit-lamp estimation of NV depth. Results: Twelve eyes with corneal NV from 12 ...
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  Mentions: Massachusetts Institute of Technology James G. Fujimoto David Huang
14. A Framework for Multiscale Quantitation of Relationships Between Choriocapillaris Flow Impairment and Geographic Atrophy Growth
  
  Explore American Journal of Ophthalmology Dec 13 2019 Ophthalmology
  
  Purpose To develop a multiscale analysis framework for investigating the relationships between geographic atrophy (GA) growth rate and choriocapillaris (CC) blood flow impairment using optical coherence tomography (OCT) and OCT angiography (OCTA). Design Retrospective case series. Methods We developed an OCT/OCTA analysis framework that quantitatively measures GA growth rates at global and local scales, and CC impairment at global, zonal, and local scales. A geometric GA growth model was ...
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  Mentions: Massachusetts Institute of Technology James G. Fujimoto Jay S. Duker
15. Global Analysis of Macular Choriocapillaris Perfusion in Dry Age-Related Macular Degeneration using Swept-Source Optical Coherence Tomography Angiography
  
  Explore IOVS Journal Dec 8 2019 Ophthalmology
  
  Purpose : Swept-source optical coherence tomography angiography (SS-OCTA) was used to investigate if the clinical stage of dry age-related macular degeneration (AMD) was correlated with global and regional macular choriocapillaris (CC) perfusion. Methods : In this retrospective, cross-sectional study, 6 6-mm SS-OCTA images from eyes with early, intermediate, and advanced dry AMD (56 eyes, 41 patients) were analyzed using algorithms described in the literature to assess regional flow deficit percentage (FD%) and ...
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  Mentions: Massachusetts Institute of Technology James G. Fujimoto Andre J. Witkin
16. Intravascular Polarimetry in Patients With Coronary Artery Disease
  
  Explore ScienceDirect Nov 22 2019 Cardiology
  
  Objectives The aims of this first-in-human pilot study of intravascular polarimetry were to investigate polarization properties of coronary plaques in patients and to examine the relationship of these features with established structural characteristics available to conventional optical frequency domain imaging (OFDI) and with clinical presentation. Background Polarization-sensitive OFDI measures birefringence and depolarization of tissue together with conventional cross-sectional optical frequency domain images of subsurface microstructure. Methods Thirty patients undergoing polarization-sensitive ...
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  Mentions: Brett E. Bouma Massachusetts Institute of Technology Leiden University
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