1. Massachusetts General Hospital

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    1. Mentioned In 669 Articles

    2. Application of maximum likelihood estimator in nano-scale optical path length measurement using spectral-domain optical coherence phase microscopy

      S. M. Motaghian Nezam, C. Joo, G. J. Tearney, J. F. de Boer Spectral-domain optical coherence phase microscopy (SD-OCPM) measures minute phase changes in transparent biological specimens using a common path interferometer and a spectrometer based optical coherence tomography system. The Fourier transform of the acquired interference spectrum in ... [Opt. Express 16, 17186-17195 (2008)]
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    3. Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging

      Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging
      ...al microscopy of the entire distal esophagus (∼6.0 cm) in patients. Design A pilot feasibility study. Setting Massachusetts General Hospital. Patients Twelve patients undergoing routine EGD. Results Comprehensive microsc...
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    4. Doppler imaging using spectrally-encoded endoscopy

      Doppler imaging using spectrally-encoded endoscopy
      Dvir Yelin, B. E. Bouma, J. J. Rosowsky, G. J. TearneyThe capability to image tissue motion such as blood flow through an endoscope could have many applications in medicine. Spectrally encoded endoscopy (SEE) is a recently introduced technique that utilizes a single optical fiber and miniature diffractive optics to obtain endoscopic images through ... [Opt. Express 16, 14836-14844 (2008)]
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    5. Apparatus for controlling at least one of at least two sections of at least one fiber

      An apparatus for controlling at least one of at least two sections of at least one fiber can be provided. The apparatus can include an arrangement which may be provided between the first and second sections of a particular continuous fiber of the fibers. A particular one of the first and second sections may be provided in a particular orientation that is perpendicular to an extension of the particular fiber ...
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    6. Comparison of coronary plaque characteristics between diabetic and non-diabetic subjects: An in vivo optical coherence tomography study

      Aims Postmortem series have reported that subjects with diabetes mellitus have coronary plaques with larger necrotic cores and increased macrophage infiltration. Optical coherence tomography (OCT) is a high-resolution imaging modality that allows in vivo characterization of atherosclerotic plaques. Using OCT imaging, we compared in vivo plaque characteristics between diabetic and non-diabetic subjects. Methods Sixty-three patients undergoing cardiac catheterization were enrolled. OCT imaging was performed in culprit coronary arteries. Assessment of ...
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    7. Cardiac Optical Coherence Tomography

      Acute coronary syndromes (ACS) are a major cause of morbidity and mortality in the developed world. The risk of future acute coronary events appears to be largely dependent on the presence of morphologically distinct, atherosclerotic plaques,1 rather than the presence of severely stenotic lesions as assessed by angiography.2 Angiography, however, cannot provide details of the vascular wall and identify these so-called "vulnerable plaques". To identify, study and potentially ...
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    8. Spectral Domain Optical Coherence Tomography for Quantitative Evaluation of Drusen and Associated Structural Changes in Non-Neovascular Age Related Macular Degeneration

      ...public of ^2 Physical Sciences Inc., Andover, Massachusetts, United States ^3 Massachusetts General Hospital, Wellman Center for Photomedicine, Boston, Massachusetts, United States ^4 Boston University, Department of Phy...
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    9. Apparatus And Method For Simultaneous Inspection At Different Depths Based On The Principle Of Frequency Domain Optical Coherence Tomography (Wo 2008/089406)

      Apparatus And Method For Simultaneous Inspection At Different Depths Based On The Principle Of Frequency Domain Optical Coherence Tomography (Wo 2008/089406)
      Exemplary embodiments of an apparatus are provided. For example, the exemplary apparatus can include at least one first arrangement providing at least one first electro- magnetic radiation to a sample, at least one second electro-magnetic radiation to a first reference and at least one third electro-magnetic radiation to a second reference. A frequency of radiation provided by the first arrangement generally varies over time. The exemplary apparatus may also include ...
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    10. In vivo association between positive coronary artery remodelling and coronary plaque characteristics assessed by intravascular optical coherence tomography

      ... Massachusetts General Hospital and Harvard Medical School, 55 Fruit Street, GRB 800, Boston, MA 02114, USA 2 Wellman Center for Photomedicine, Massachusetts General Hospital and Harvard Medical School, Boston, MA, USA 3...
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    11. Single-detector polarization-sensitive optical frequency domain imaging using high-speed intra A-line polarization modulation

      We demonstrate a novel high-speed polarization-sensitive optical frequency domain imaging system employing high-speed polarization modulation. Rapid and continuous polarization modulation of light prior to illumination of the sample is accomplished by shifting the frequency of one polarization ... [Opt. Lett. 33, 1330-1332 (2008)]
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    12. Fiber-optic rotational device, optical system and method for imaging a sample

      A device, system and method for transmitting electro-magnetic radiation between at least two separate fibers (as well as for imaging a sample) are provided. For example, a first optical fiber and a second optical fiber may be provided, such that the first and/or second fibers is/are rotatable. At least one first optical arrangement may also be included which communicates with at least one end of the first optical ...
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    13. Association of statin therapy with reduced coronary plaque rupture: an optical coherence tomography study.

      Coronary Artery Disease. 19(4):237-242, June 2008. Chia, Stanley a; Raffel, Owen Christopher a; Takano, Masamichi c; Tearney, Guillermo J. b; Bouma, Brett E. b; Jang, Ik-Kyung a Abstract: Objective: Statin therapy induces plaque regression and may stabilize atheromatous plaques. Optical coherence tomography (OCT) is a high-resolution in-vivo imaging modality that allows characterization of atherosclerotic plaques. We aimed to demonstrate the potential utility of OCT in evaluating coronary plaque
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    14. System and method for optical coherence imaging

      A system and method for imaging of a sample, e.g., biological sample, are provided. In particular, at least one source electro-magnetic radiation forwarded to the sample and a reference may be generated. A plurality of detectors may be used, at least one of the detectors capable of detecting a signal associated with a combination of at least one first electro-magnetic radiation received from the sample and at least one ...
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    15. System and method for optical coherence imaging

      Apparatus and method are provided for transmitting at least one electro-magnetic radiation is provided. In particular, at least one optical fiber having at least one end extending along a first axis may be provided. Further, a light transmissive optical arrangement may be provided in optical cooperation with the optical fiber. The optical arrangement may have a first surface having a portion that is perpendicular to a second axis, and a ...
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    16. 616-630 of 669 « 1 2 ... 39 40 41 42 43 44 45 »
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  2. About Massachusetts General Hospital

    Massachusetts General Hospital

    Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center).

  3. Quotes about Massachusetts General Hospital

    1. We are excited to see the publication of this data from our collaborators at Massachusetts General Hospital that clearly demonstrate the imaging technology can produce valuable images of esophageal tissue...We look forward to moving ahead with continued development of this exciting new technology.
      Charles Carignan in NinePoint Medical Imaging Technology Highlighted in Nature Medicine