1. Massachusetts General Hospital

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    1. Mentioned In 682 Articles

    2. OCT-guided laser therapy shows promise

      OCT-guided laser therapy shows promise
      Advances in optical-coherence tomography may lead to a new class of endoscopic, image-guided therapies that target disease with microscopic precision. Nearly 15 years of technical innovation, robust engineering, and cross-disciplinary collaboration have advanced endoscopic optical-coherence tomography1 (OCT) from a promising laboratory tool to clinically deployed instrumentation. The latest OCT technologies are being studied at research hospitals throughout the world for applications such as heart disease and cancer.2 One of ...
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    3. Optical Coherence Tomography (OCT) Reveals Depth-Resolved Dynamics during Functional Brain Activation

      Optical intrinsic signal imaging (OISI) provides two-dimensional, depth-integrated activation maps of brain activity. Optical coherence tomography (OCT) provides depth-resolved, cross-sectional images of functional brain activation. Co-registered OCT and OISI imaging was performed simultaneously on the rat somatosensory cortex through a thinned skull during forepaw electrical stimulation. Fractional signal change measurements made by OCT revealed a functional signal that correlates well with that of the intrinsic hemodynamic signals and provides depth-resolved ...
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    4. Long-wavelength optical coherence tomography at 1.7 μm for enhanced imaging depth

      Long-wavelength optical coherence tomography at 1.7 μm for enhanced imaging depth
      Multiple scattering in a sample presents a significant limitation to achieve meaningful structural information at deeper penetration depths in optical coherence tomography (OCT). Previous studies suggest that the spectral region around 1.7 m may exhibit reduced scattering coefficients in ... [Opt. Express 16, 19712-19723 (2008)]
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    5. Distance From the Coronary Ostium as a Predictor of Vulnerable Plaque Morphology; An In-vivo Optical Coherence Tomography Study

      Distance From the Coronary Ostium as a Predictor of Vulnerable Plaque Morphology; An In-vivo Optical Coherence Tomography Study
      Background: Plaque morphology predicts its vulnerability to cause acute coronary events; most of which occur due to disruption of lipid-rich thin-cap fibroatheroma (TCFA). Observational studies show that lesions causing acute events are clustered in the proximal coronary artery segments. Aim: To evaluate whether the location of plaque in the coronary vessel is predictive of vulnerable plaque morphology identified by optical coherence tomography (OCT). Methods: OCT was performed in patients undergoing ...
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    6. Imaging system and related techniques

      BACKGROUND OF THE INVENTION As is known in the art, fiber optic endoscopy is typically conducted by transmitting an image through an array of fibers often referred to as a fiber bundle. While successful for a variety of medical and non-medical applications, utilization of an array of fibers to form the image imposes constraints on the cost, diameter, and flexibility of the imaging device. In an attempt to overcome these ...
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    7. Application of maximum likelihood estimator in nano-scale optical path length measurement using spectral-domain optical coherence phase microscopy

      S. M. Motaghian Nezam, C. Joo, G. J. Tearney, J. F. de Boer Spectral-domain optical coherence phase microscopy (SD-OCPM) measures minute phase changes in transparent biological specimens using a common path interferometer and a spectrometer based optical coherence tomography system. The Fourier transform of the acquired interference spectrum in ... [Opt. Express 16, 17186-17195 (2008)]
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    8. Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging

      Comprehensive microscopy of the esophagus in human patients with optical frequency domain imaging
      ...al microscopy of the entire distal esophagus (∼6.0 cm) in patients. Design A pilot feasibility study. Setting Massachusetts General Hospital. Patients Twelve patients undergoing routine EGD. Results Comprehensive microsc...
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  2. About Massachusetts General Hospital

    Massachusetts General Hospital

    Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center).

  3. Quotes about Massachusetts General Hospital

    1. We are excited to see the publication of this data from our collaborators at Massachusetts General Hospital that clearly demonstrate the imaging technology can produce valuable images of esophageal tissue...We look forward to moving ahead with continued development of this exciting new technology.
      Charles Carignan in NinePoint Medical Imaging Technology Highlighted in Nature Medicine