1. Massachusetts General Hospital

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    1. Mentioned In 879 Articles

    2. Coronary plaque and clinical characteristics of South Asian (Indian) patients with acute coronary syndromes: An optical coherence tomography study

      Coronary plaque and clinical characteristics of South Asian (Indian) patients with acute coronary syndromes: An optical coherence tomography study
      Background South Asians, and Indians in particular, are known to have a higher incidence of premature atherosclerosis and acute coronary syndromes (ACS) with worse clinical outcomes, compared to populations with different ethnic backgrounds. However, the underlying pathobiology accounting for these differences has not been fully elucidated. Methods ACS patients who had culprit lesion optical coherence tomography (OCT) imaging were enrolled. Culprit plaque characteristics were evaluated using OCT. Results Among 1315 ...
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    3. Diagnostic Accuracy of Endobronchial Optical Coherence Tomography for the Microscopic Diagnosis of Usual Interstitial Pneumonia

      Diagnostic Accuracy of Endobronchial Optical Coherence Tomography for the Microscopic Diagnosis of Usual Interstitial Pneumonia
      Rationale: Early, accurate diagnosis of interstitial lung disease (ILD) informs prognosis and therapy, especially in idiopathic pulmonary fibrosis (IPF). Current diagnostic methods are imperfect. HRCT resolution is limited while surgical lung biopsy (SLB) carries risks of morbidity/mortality. Endobronchial optical coherence tomography (EB-OCT) is a low-risk, bronchoscope-compatible modality that images large lung volumes in vivo with microscopic resolution, including subpleural lung, and has the potential to improve the diagnostic accuracy ...
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    4. MGH Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobronchial Optical Coherence Tomography

      MGH Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobronchial Optical Coherence Tomography
      ...sis on optics and signal processing. Since beginning postdoctoral research at Massachusetts General Hospital (MGH), he has worked on developing novel data processing techniques to maximize the utilization of data obtaine...
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    5. Robust and easy-to-operate stretched-pulse mode-locked wavelength-swept laser with an all-polarization-maintaining fiber cavity for 10 MHz A-line rate optical coherence tomography

      Robust and easy-to-operate stretched-pulse mode-locked wavelength-swept laser with an all-polarization-maintaining fiber cavity for 10 MHz A-line rate optical coherence tomography
      We demonstrate robust and easy-to-operate stretched-pulse mode-locked laser (SPML) architectures using all-polarization-maintaining fiber laser cavities. Because of the polarization-maintaining construction, the laser performance is unaffected by mechanical perturbation on the cavity fibers. The lasers automatically initiate linear-in-wavenumber sweeps across 100 nm centered at 1290 nm with a 10 MHz repetition rate. OCT imaging with a sensitivity of 98 dB and a single-sided 6 dB coherence length of 2.5 mm ...
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    6. Clinical outcomes of low-intensity area without attenuation and cholesterol crystals in non-culprit lesions assessed by optical coherence tomography

      Clinical outcomes of low-intensity area without attenuation and cholesterol crystals in non-culprit lesions assessed by optical coherence tomography
      Background and aims Pathologists have shown that intraplaque hemorrhage contributes to plaque destabilization and is frequently co-located with cholesterol crystals (CC). Optical coherence tomography (OCT)-detected low-intensity area without attenuation (LIA) may represent intraplaque hemorrhage. We aimed to examine the prevalence and impact of OCT-detected LIA + CC in untreated non-culprit lesions (NCLs) on subsequent major adverse cardiac events (MACE). Methods OCT imaged NCLs in the culprit vessel in the patients ...
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    7. Layer-based, depth-resolved computation of attenuation coefficients and backscattering fractions in tissue using optical coherence tomography

      Layer-based, depth-resolved computation of attenuation coefficients and backscattering fractions in tissue using optical coherence tomography
      Structural optical coherence tomography (OCT) images of tissue stand to benefit from greater functionalization and quantitative interpretation. The OCT attenuation coefficient , an analogue of the imaged samples scattering coefficient, offers potential functional contrast based on the relationship of to sub-resolution physical properties of the sample. Attenuation coefficients are computed either by fitting a representative over several depth-wise pixels of a samples intensity decay, or by using previously-developed depth-resolved attenuation algorithms ...
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    8. Massachusetts General Hospital Receives NIH Grant for Less Invasive Assessment of Inflammation and Subepithelial Remodeling in Eosinophilic Esophagitis Patients.

      Massachusetts General Hospital Receives NIH Grant for Less Invasive Assessment of Inflammation and Subepithelial Remodeling in Eosinophilic Esophagitis Patients.
      ...ze food re-introduction intervals during dietary exclusion protocols (Aim 3).

      Massachusetts General Hospital Receives a 2021 NIH Grant for $716,240 for Less Invasive Assessment of Inflamma...

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    9. Dual-modality optical coherence tomography and fluorescence tethered capsule endomicroscopy

      Dual-modality optical coherence tomography and fluorescence tethered capsule endomicroscopy
      OCT tethered capsule endomicroscopy (TCE) is an emerging noninvasive diagnostic imaging technology for gastrointestinal (GI) tract disorders. OCT measures tissue reflectivity that provides morphologic image contrast, and thus is incapable of ascertaining molecular information that can be useful for improving diagnostic accuracy. Here, we introduce an extension to OCT TCE that includes a fluorescence (FL) imaging channel for attaining complementary, co-registered molecular contrast. We present the development of an OCT-FL ...
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    10. Massachusetts General Hospital Receives NIH Grant for Imaging and Analysis Techniques to Construct a Cell census Atlas of the Human Brain Admin Supplement

      Massachusetts General Hospital Receives NIH Grant for Imaging and Analysis Techniques to Construct a Cell census Atlas of the Human Brain Admin Supplement
      ...ese labelings including the assessment of intra- and inter-rater reliability.

      Massachusetts General Hospital Receives a 2021 NIH Grant for $99,916 for Imaging and Analysis Techniques to Co...

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    11. 46-60 of 879 « 1 2 3 4 5 6 7 ... 57 58 59 »
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  2. About Massachusetts General Hospital

    Massachusetts General Hospital

    Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center).

  3. Quotes about Massachusetts General Hospital

    1. We are excited to see the publication of this data from our collaborators at Massachusetts General Hospital that clearly demonstrate the imaging technology can produce valuable images of esophageal tissue...We look forward to moving ahead with continued development of this exciting new technology.
      In NinePoint Medical Imaging Technology Highlighted in Nature Medicine