1. Massachusetts General Hospital

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    1. Mentioned In 689 Articles

    2. Processing-based approach for resolving the sample optic axis in endoscopic polarization-sensitive optical coherence tomography

      Explore OSA | OSA Publishing Probes
      Processing-based approach for resolving the sample optic axis in endoscopic polarization-sensitive optical coherence tomography
      Fiber-based polarization-sensitive optical coherence tomography (PS-OCT) that utilizes a rotationally-scanning catheter has a variety of potential biomedical applications in luminal organ systems due to its ability to provide intrinsic contrast for birefringent tissue. Incorporating the optic axis (OA) of the tissue greatly enhances this potential by also permitting information about the orientation of the tissue to be extracted; however, measurement distortion that occurs has up to this point made it ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    3. Nano-optic endoscope for high-resolution optical coherence tomography in vivo

      Explore Nature Publishing Group Gastroenterology , Probes
      Nano-optic endoscope for high-resolution optical coherence tomography in vivo
      Acquisition of high-resolution images from within internal organs using endoscopic optical imaging has numerous clinical applications. However, difficulties associated with optical aberrations and the trade-off between transverse resolution and depth of focus significantly limit the scope of applications. Here, we integrate a metalens, with the ability to modify the phase of incident light at subwavelength level, into the design of an endoscopic optical coherence tomography catheter (termed nano-optic endoscope) to ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    4. Differences in coronary plaque morphology between East Asian and Western White patients: an optical coherence tomography study

      Explore LWW Online Cardiology
      Differences in coronary plaque morphology between East Asian and Western White patients: an optical coherence tomography study
      Aims Prevalence of coronary artery disease as well as cardiac mortality varies between Asian and White patients. However, the link between race and plaque characteristics in patients with coronary artery disease remains largely unexplored. Thus, we aimed to investigate the detailed culprit plaque characteristics between East Asian and White patients using optical coherence tomography . Patients and methods A total of 101 East Asians were matched to 101 White patients. Matching ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University

    5. Quantitative depolarization measurements for fiber‐based polarization‐sensitive optical frequency domain imaging of the retinal pigment epithelium

      Explore Wiley Online Library Ophthalmology
      Quantitative depolarization measurements for fiber‐based polarization‐sensitive optical frequency domain imaging of the retinal pigment epithelium
      A full quantitative evaluation of the depolarization of light may serve to assess concentrations of depolarizing particles in the retinal pigment epithelium and to investigate their role in retinal diseases in the human eye. Optical coherence tomography (OCT) and optical frequency domain imaging (OFDI) use spatial incoherent averaging to compute depolarization. Depolarization depends on accurate measurements of the polarization states at the receiver but also on the polarization state incident ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    6. Volumetric non-local-means based speckle reduction for optical coherence tomography

      Explore OSA | OSA Publishing
      Volumetric non-local-means based speckle reduction for optical coherence tomography
      We present a novel tomographic non-local-means based despeckling technique, TNode, for optical coherence tomography. TNode is built upon a weighting similarity criterion derived for speckle in a three-dimensional similarity window. We present an implementation using a two-dimensional search window, enabling the despeckling of volumes in the presence of motion artifacts, and an implementation using a three-dimensional window with improved performance in motion-free volumes. We show that our technique provides effective ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    7. NinePoint Medical Appoints Eman Namati, Ph.D., to Chief Executive Officer

      Explore Optical Coherence Tomography News Gastroenterology , Other Business News
      NinePoint Medical Appoints Eman Namati, Ph.D., to Chief Executive Officer
      ...ing system. Prior to his time at NinePoint, Dr. Namati was a researcher developing optical imaging systems at Massachusetts General Hospital. He worked with Professors Guillermo Tearney, M.D., Ph.D., and Brett Bouma, Ph....
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      Mentions: Guillermo J. Tearney Brett E. Bouma Massachusetts General Hospital

    9. Ruptures and Thickening : Optical Coherence Tomography as the Arbiter of the Fibrous Cap

      Explore ScienceDirect Cardiology
      Ruptures and Thickening : Optical Coherence Tomography as the Arbiter of the Fibrous Cap
      Coronary artery disease remains a leading cause of mortality worldwide, primarily through acute events mediated by progression and disruption of thrombosis-provoking atheroma. The necrotic core of advanced atheroma harbors highly prothrombotic material, including components of tissue factor, von Willebrand factor, and plasminogen activator inhibitor1. Exposure of these contents to flowing blood can spur thrombosis and is a critical feature of many acute coronary syndromes (ACS). It is therefore vital that ...
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      Mentions: Massachusetts General Hospital Harvard University University of Minnesota

    10. Wide dynamic range high-speed three-dimensional quantitative OCT angiography with a hybrid-beam scan

      Explore OSA | OSA Publishing
      Wide dynamic range high-speed three-dimensional quantitative OCT angiography with a hybrid-beam scan
      We demonstrate a novel hybrid-beam scanning-based quantitative optical coherence tomography angiography (OCTA) that provides high-speed wide dynamic range blood flow speed imaging. The hybrid-beam scanning scheme enables multiple OCTA image acquisitions with a wide range of multiple time intervals simultaneously providing wide dynamic range blood flow speed imaging independent of the blood vessel orientation, which was quantified over a speed range of 0.6 104 mm / s 0.6104mm/s ...
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      Mentions: Massachusetts General Hospital Harvard University Wang Yuhl Oh

    11. Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging

      Explore uspto.gov Patents
      Apparatus and method for providing diffuse spectroscopy co-registered with optical frequency domain imaging
      An apparatus can be provided according to certain exemplary embodiments. For example, the apparatus can include a waveguiding first arrangement providing at least one electromagnetic radiation. A configuration can be provided that receives and splits the at least one electromagnetic radiation into a first radiation and a second radiation. The apparatus can further include a waveguiding second arrangement which has a first waveguide and a second waveguide, whereas the first ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    12. Needle-based Optical Coherence Tomography to Guide Transbronchial Lymph Node Biopsy

      Explore LWW Online Pulmonology
      Needle-based Optical Coherence Tomography to Guide Transbronchial Lymph Node Biopsy
      Background: Transbronchial needle aspiration (TBNA), often used to sample lymph nodes for lung cancer staging , is subject to sampling error even when performed with endobronchial ultrasound. Optical coherence tomography (OCT) is a high-resolution imaging modality that rapidly generates helical cross-sectional images. We aim to determine if needle-based OCT can provide microstructural information in lymph nodes that may be used to guide TBNA, and improve sampling error. Methods: We performed ex ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    13. Robust wavenumber and dispersion calibration for Fourier-domain optical coherence tomography

      Explore OSA | OSA Publishing
      Robust wavenumber and dispersion calibration for Fourier-domain optical coherence tomography
      Many Fourier-domain optical coherence tomography (FD-OCT) systems sample the interference fringes with a non-uniform wavenumber ( k ) interval, introducing a chirp to the signal that depends on the path length difference underlying each fringe. A dispersion imbalance between sample and reference arms also generates a chirp in the fringe signal which, in contrast, is independent of depth. Fringe interpolation to obtain a signal linear in k and compensate dispersion imbalance is ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    15. Optical coherence tomography (OCT) imaging of dynamic airway behavior in an asthma model

      Explore SPIE Digital Library Pulmonology
      Optical coherence tomography (OCT) imaging of dynamic airway behavior in an asthma model
      To better understand bronchoconstriction in asthma, it is critical to dynamically visualize airway behavior in vivo. However, currently available imaging techniques do not have sufficient temporal and spatial resolution to investigate airway dynamics. We propose to use endobronchial Optical Coherence Tomography (OCT) to provide real-time cross-sectional images of airway dynamics with a high spatial resolution. Our aim was to study the structure and function of spatially distinct airways during tidal ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    16. Visualizing cellular markers of sensorineural hearing loss in the murine cochlea using micro-optical coherence tomography

      Explore SPIE Digital Library Otolaryngology
      Visualizing cellular markers of sensorineural hearing loss in the murine cochlea using micro-optical coherence tomography
      Although sensorineural hearing loss (SNHL) affects 600 million people globally and its prevalence is increasing, therapies remain limited. Advances in therapy development for SNHL are slow because we do not possess a method for visualizing the cochleas interior in living humans and relating visualized pathology to a patients hearing ability. To this end, we are investigating the ability of micro-optical coherence tomography (OCT), a low-coherence interferometric imaging technique that requires ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University
    17. 46-60 of 689 « 1 2 3 4 5 6 7 ... 44 45 46 »
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  4. About Massachusetts General Hospital

    Massachusetts General Hospital

    Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center).

  5. Related Topics

    1. Optical methods for tissue analysis
      602 articles also mentioned Harvard University
    2. Optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques
      135 articles also mentioned Ik-Kyung Jang
    3. Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography.
      92 articles also mentioned Massachusetts Institute of Technology
    4. High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing
      75 articles also mentioned Benjamin J. Vakoc
    5. 1st Massachusetts General Hospital OCT Registry Symposium Scheduled for March 13, 2010
      63 articles also mentioned Massachusetts General Hospital OCT Registry

  6. Quotes about Massachusetts General Hospital

    1. We are excited to see the publication of this data from our collaborators at Massachusetts General Hospital that clearly demonstrate the imaging technology can produce valuable images of esophageal tissue...We look forward to moving ahead with continued development of this exciting new technology.
      Charles Carignan in NinePoint Medical Imaging Technology Highlighted in Nature Medicine