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    1. Mentioned In 651 Articles

    3. Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann’s area 32 and area 21

      Explore Home - Springer Neurology
      Colocalization of neurons in optical coherence microscopy and Nissl-stained histology in Brodmann’s area 32 and area 21
      Optical coherence tomography is an optical technique that uses backscattered light to highlight intrinsic structure, and when applied to brain tissue, it can resolve cortical layers and fiber bundles. Optical coherence microscopy (OCM) is higher resolution (i.e., 1.25 m) and is capable of detecting neurons. In a previous report, we compared the correspondence of OCM acquired imaging of neurons with traditional Nissl stained histology in entorhinal cortex layer ...
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      Mentions: Massachusetts Institute of Technology Massachusetts General Hospital Boston University

    4. Optic axis mapping with catheter-based polarization-sensitive optical coherence tomography

      Explore OSA | OSA Publishing Cardiology , Probes
      Optic axis mapping with catheter-based polarization-sensitive optical coherence tomography
      Birefringence offers an intrinsic contrast mechanism related to the microstructure and arrangement of fibrillary tissue components. Here we present a reconstruction strategy to recover not only the scalar amount of birefringence, but also its optic axis orientation as a function of depth in tissue from measurements with catheter-based polarization-sensitive optical coherence tomography. A polarization symmetry constraint, intrinsic to imaging in the backscatter direction, facilitates the required compensation for wavelength-dependent transmission ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    5. Diagnostic Capability of Three-Dimensional Macular Parameters for Glaucoma Using Optical Coherence Tomography Volume Scans

      Explore IOVS Journal Ophthalmology
      Diagnostic Capability of Three-Dimensional Macular Parameters for Glaucoma Using Optical Coherence Tomography Volume Scans
      Purpose : To compare the diagnostic capability of three-dimensional (3D) macular parameters against traditional two-dimensional (2D) retinal nerve fiber layer (RNFL) thickness using spectral domain optical coherence tomography. To determine if manual correction and interpolation of B-scans improve the ability of 3D macular parameters to diagnose glaucoma. Methods : A total of 101 open angle glaucoma patients (29 with early glaucoma) and 57 healthy subjects had peripapillary 2D RNFL thickness and 3D ...
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      Mentions: Brett E. Bouma Johannes F. de Boer Johns Hopkins University

    6. Extended coherence length and depth ranging using a Fourier domain mode-locked frequency comb and circular interferometric ranging

      Explore arxiv.org Tunable Sources
      Extended coherence length and depth ranging using a Fourier domain mode-locked frequency comb and circular interferometric ranging
      Fourier domain mode-locking (FDML) has been a popular laser design for high speed optical frequency domain imaging (OFDI) but achieving long coherence lengths, and therefore imaging range, has been challenging. The narrow instantaneous linewidth of a frequency comb (FC) FDML laser could provide an attractive platform for high speed as well as long range OFDI. Unfortunately, aliasing artifacts arising from signals beyond the principle measurement depth of the free spectral ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    9. Processing-based approach for resolving the sample optic axis in endoscopic polarization-sensitive optical coherence tomography

      Explore OSA | OSA Publishing Probes
      Processing-based approach for resolving the sample optic axis in endoscopic polarization-sensitive optical coherence tomography
      Fiber-based polarization-sensitive optical coherence tomography (PS-OCT) that utilizes a rotationally-scanning catheter has a variety of potential biomedical applications in luminal organ systems due to its ability to provide intrinsic contrast for birefringent tissue. Incorporating the optic axis (OA) of the tissue greatly enhances this potential by also permitting information about the orientation of the tissue to be extracted; however, measurement distortion that occurs has up to this point made it ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    10. Nano-optic endoscope for high-resolution optical coherence tomography in vivo

      Explore Nature Publishing Group Gastroenterology , Probes
      Nano-optic endoscope for high-resolution optical coherence tomography in vivo
      Acquisition of high-resolution images from within internal organs using endoscopic optical imaging has numerous clinical applications. However, difficulties associated with optical aberrations and the trade-off between transverse resolution and depth of focus significantly limit the scope of applications. Here, we integrate a metalens, with the ability to modify the phase of incident light at subwavelength level, into the design of an endoscopic optical coherence tomography catheter (termed nano-optic endoscope) to ...
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      Mentions: Massachusetts General Hospital Harvard University Melissa J. Suter

    11. Differences in coronary plaque morphology between East Asian and Western White patients: an optical coherence tomography study

      Explore LWW Online Cardiology
      Differences in coronary plaque morphology between East Asian and Western White patients: an optical coherence tomography study
      Aims Prevalence of coronary artery disease as well as cardiac mortality varies between Asian and White patients. However, the link between race and plaque characteristics in patients with coronary artery disease remains largely unexplored. Thus, we aimed to investigate the detailed culprit plaque characteristics between East Asian and White patients using optical coherence tomography . Patients and methods A total of 101 East Asians were matched to 101 White patients. Matching ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University

    12. Quantitative depolarization measurements for fiber‐based polarization‐sensitive optical frequency domain imaging of the retinal pigment epithelium

      Explore Wiley Online Library Ophthalmology
      Quantitative depolarization measurements for fiber‐based polarization‐sensitive optical frequency domain imaging of the retinal pigment epithelium
      A full quantitative evaluation of the depolarization of light may serve to assess concentrations of depolarizing particles in the retinal pigment epithelium and to investigate their role in retinal diseases in the human eye. Optical coherence tomography (OCT) and optical frequency domain imaging (OFDI) use spatial incoherent averaging to compute depolarization. Depolarization depends on accurate measurements of the polarization states at the receiver but also on the polarization state incident ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    13. Volumetric non-local-means based speckle reduction for optical coherence tomography

      Explore OSA | OSA Publishing
      Volumetric non-local-means based speckle reduction for optical coherence tomography
      We present a novel tomographic non-local-means based despeckling technique, TNode, for optical coherence tomography. TNode is built upon a weighting similarity criterion derived for speckle in a three-dimensional similarity window. We present an implementation using a two-dimensional search window, enabling the despeckling of volumes in the presence of motion artifacts, and an implementation using a three-dimensional window with improved performance in motion-free volumes. We show that our technique provides effective ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Massachusetts General Hospital

    14. NinePoint Medical Appoints Eman Namati, Ph.D., to Chief Executive Officer

      Explore Optical Coherence Tomography News Gastroenterology , Other Business News
      NinePoint Medical Appoints Eman Namati, Ph.D., to Chief Executive Officer
      ...ing system. Prior to his time at NinePoint, Dr. Namati was a researcher developing optical imaging systems at Massachusetts General Hospital. He worked with Professors Guillermo Tearney, M.D., Ph.D., and Brett Bouma, Ph....
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      Mentions: Guillermo J. Tearney Brett E. Bouma Massachusetts General Hospital

    16. Ruptures and Thickening : Optical Coherence Tomography as the Arbiter of the Fibrous Cap

      Explore ScienceDirect Cardiology
      Ruptures and Thickening : Optical Coherence Tomography as the Arbiter of the Fibrous Cap
      Coronary artery disease remains a leading cause of mortality worldwide, primarily through acute events mediated by progression and disruption of thrombosis-provoking atheroma. The necrotic core of advanced atheroma harbors highly prothrombotic material, including components of tissue factor, von Willebrand factor, and plasminogen activator inhibitor1. Exposure of these contents to flowing blood can spur thrombosis and is a critical feature of many acute coronary syndromes (ACS). It is therefore vital that ...
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      Mentions: Massachusetts General Hospital Harvard University University of Minnesota
    17. 1-15 of 651 1 2 3 4 ... 42 43 44 »
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  4. About Massachusetts General Hospital

    Massachusetts General Hospital

    Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center).

  5. Related Topics

    1. Optical methods for tissue analysis
      576 articles also mentioned Harvard University
    2. Optical coherence tomography (OCT) can successfully identify the characteristics of coronary plaques
      132 articles also mentioned Ik-Kyung Jang
    3. Power-efficient nonreciprocal interferometer and linear-scanning fiber-optic catheter for optical coherence tomography.
      88 articles also mentioned Massachusetts Institute of Technology
    4. High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing
      66 articles also mentioned Benjamin J. Vakoc
    5. 1st Massachusetts General Hospital OCT Registry Symposium Scheduled for March 13, 2010
      62 articles also mentioned Massachusetts General Hospital OCT Registry

  6. Quotes about Massachusetts General Hospital

    1. We are excited to see the publication of this data from our collaborators at Massachusetts General Hospital that clearly demonstrate the imaging technology can produce valuable images of esophageal tissue...We look forward to moving ahead with continued development of this exciting new technology.
      Charles Carignan in NinePoint Medical Imaging Technology Highlighted in Nature Medicine