Massachusetts General Hospital

Massachusetts General Hospital wins NIH Grant to on Development of a Preclinical Optical Frequency Domain Angiography Instrument

Explore Optical Coherence Tomography News (May 8 2012) Cardiology , Funding

...nslation into the biological laboratory. Our approach will unite investigators and resources at the Massachusetts General Hospital (MGH) and Physical Sciences, Incorporated (PSI). Innovations to the OFDA instrumentation and core algori... (Read Full Article)

Comment Mentions:   Massachusetts General Hospital   Harvard University   Benjamin J. Vakoc

Extracting structural features of rat sciatic nerve using polarization-sensitive spectral domain optical coherence tomography

Explore Linking to Scitation Content (May 4 2012) Neurology

We present spectral domain polarization-sensitive optical coherence tomography (SD PS-OCT) imaging of peripheral nerves. Structural and polarization-sensitive OCT imaging of uninjured rat sciatic nerves was evaluated both qualitatively and quantitatively. OCT and its functional extension, PS-OCT, were used to image sciatic nerve structure with clear delineation of the nerve boundaries to muscle and adipose tissues. A long-known optical effect, bands of Fontana, was also observed. Postprocessing analysis of these images ... (Read Full Article)

Comment Mentions:   Johannes F. de Boer   B. Hyle Park   Massachusetts General Hospital

Feasibility and Safety of the Second-Generation, Frequency Domain Optical Coherence Tomography (FD-OCT): A Multicenter Study

Explore Invasive Cardiology (Apr 26 2012) Cardiology

Abstract: Objectives. This study sought to assess the effectiveness and safety of the second-generation frequency-domain optical coherence tomography (FD-OCT) system. Background. The second-generation FD-OCT was recently developed, with simplified imaging technique and faster acquisition time compared to the first-generation time-domain OCT. However, the safety and effectiveness of the FD-OCT has not been evaluated, and this study was conceived as a pre-approval study for Food and Drug Administration clearance for clinical ... (Read Full Article)

Comment Mentions:   Case Western Reserve University   Columbia University   Massachusetts General Hospital

Shining Light and Illuminating Murine Atherosclerosis via Optical Coherence Tomography

Explore atvb.ahajournals.org (Apr 18 2012) Cardiology

...om the Cardiovascular Research Center (F.A.J.), Center for Molecular Imaging Research (F.A.J.), and Wellman Center for Photomedicine (F.A.J.), Massachusetts General Hospital, Harvard Medical School, Boston, MA. See accompanying article on page 1150 In this issue of Arterio... (Read Full Article)

Comment Mentions:   Massachusetts General Hospital   Harvard University   Zhao Wang

Vice President of Sales Position Opening at NinePoint Medical

Explore Optical Coherence Tomography News (Apr 14 2012) Jobs & Studentships

...cedures. These products are based on an Optical Coherence Tomography (OCT) technology licensed from Massachusetts General Hospital called optical frequency domain imaging (OFDI). Integrating the company’s proprietary imaging techn... (Read Full Article)

Comment Mentions:   Massachusetts General Hospital   Boston Scientific   NinePoint Medical

Cancer imaging by optical coherence tomography: preclinical progress and clinical potential

Explore Nature Publishing Group (Apr 8 2012) Oncology

The past decade has seen dramatic technological advances in the field of optical coherence tomography (OCT) imaging. These advances have driven commercialization and clinical adoption in ophthalmology, cardiology and gastrointestinal cancer screening. Recently, an array of OCT-based imaging tools that have been developed for preclinical intravital cancer imaging applications has yielded exciting new capabilities to probe and to monitor cancer progression and response in vivo. Here, we review these results ... (Read Full Article)

Comment Mentions:   Brett E. Bouma   Massachusetts General Hospital   Harvard University

Speckle reduction in optical coherence tomography by path length encoded angular compounding

Explore wipo.int (Apr 5 2012) Patents

Apparatus for irradiating a sample, comprising an interferometer forwarding an electromagnetic radiation and a sample arm receiving the electromagnetic radiation, wherein the sample arm includes an arrangement which is configured to produce at least two radiations from the electromagnetic radiation so as to irradiate the sample, and to delay a first radiation of the at least two radiations with respect to a second radiation of the at least two radiations. (Read Full Article)

Comment Mentions:   Guillermo J. Tearney   Brett E. Bouma   Massachusetts General Hospital

CBORT OCT Technical Foundations and Systematic Implementation Summer Workshop 2012 July 30-31st, Cambridge MA, USA.

Explore Optical Coherence Tomography News (Apr 2 2012)

The Center for Biomedical OCT Research and Translation (CBORT), at Massachusetts General Hospital and Harvard Medical School is hosting its first annual OCT workshop, OCT: Technical Foundations and......ew of their application. For more information click HERE. Please contact Jacqueline Namati, jnamati@mgh.harvard.edu , with any questions. The Center for Biomedical OCT Research and Translation (CBORT), a... (Read Full Article)

Comment Mentions:   Guillermo J. Tearney   Brett E. Bouma   Seok-Hyun Yun

ComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER Oct)

Explore American Heart Journal (Mar 31 2012) Cardiology

Background Data on strut surface coverage of second-generation drug-eluting stents (DES) are limited. We investigated stent strut coverage of resolute zotarolimus-eluting stent (ZES-R) or everolimus-eluting stent (EES) at 9 months after implantation using optical coherence tomography (OCT). Methods ComparisOn of neointimal coVerage betwEen zotaRolimus-eluting stent and everolimus-eluting stent using Optical Coherence Tomography (COVER OCT) is a prospective, randomized, multicenter trial comparing ZES-R to EES using OCT at 9 months after ... (Read Full Article)

Comment Mentions:   Massachusetts General Hospital   Ik-Kyung Jang   Harvard University

Third Annual Optical Coherence Tomography (OCT) Symposium in Association with Massachusetts General Hospital (MGH) March 25, 2012

Explore Optical Coherence Tomography News (Mar 15 2012) Cardiology

The 3rd Annual Optical Coherence Tomography Symposium in Association with Massachusetts General Hospital will be held in Chicago conjunction with American College of Cardiology this year. Speakers include... (Read Full Article)

Comment Mentions:   Case Western Reserve University   Massachusetts General Hospital   Ik-Kyung Jang

Neointimal tissue characteristics following sirolimus-eluting stent implantation: OCT quantitative tissue property analysis

Explore SpringerLink Home (Mar 15 2012) Cardiology

The neointimal tissue characteristics inside sirolimus-eluting stent (SES) were evaluated by optical coherence tomography (OCT) according to follow-up duration. One hundred and thirty-three Optical coherence tomography was performed in 96 patients with 143 SES which were retrospectively included and divided into 2 groups according to follow-up duration: Group 1, 24 months (35 stents in 25 patients). The neointimal tissue coverage pattern and characteristics were studied using a new OCT analysis ... (Read Full Article)

Comment Mentions:   Joseph M. Schmitt   Massachusetts General Hospital   Ik-Kyung Jang

Consensus Standards for Acquisition, Measurement, and Reporting of Intravascular Optical Coherence Tomography Studies: A Report From the International Working Group for Intravascular Optical Coherence Tomography Standardization and Validation

Explore JACC (Mar 12 2012) Cardiology

...2011, accepted September 27, 2011. ^ Reprint requests and correspondence. Dr. Guillermo J. Tearney, Wellman Center for Photomedicine, Massachusetts General Hospital, BAR703, Boston, Massachusetts 02114 (Email: gtearney{at}partners.org). Objectives: The purpose of ... (Read Full Article)

Comment Mentions:   Guillermo J. Tearney   Brett E. Bouma   Andrew M. Rollins

Dual-modality fluorescence and full-field optical coherence microscopy for biomedical imaging applications

Explore opticsinfobase.org (Feb 27 2012) Microscopy

Full-field optical coherence microscopy (FFOCM) is a high-resolution interferometric technique that is particularly attractive for biomedical imaging. Here we show that combining it with structured illumination fluorescence microscopy on one platform can increase its versatility since it enables co-localized registration of optically sectioned reflectance and fluorescence images. To demonstrate the potential of this dual modality, a fixed and labeled mouse retina was imaged. Results showed that both techniques can provide ... (Read Full Article)

Comment Mentions:   Guillermo J. Tearney   Brett E. Bouma   Massachusetts General Hospital

OCT methods for capillary velocimetry

Explore opticsinfobase.org (Feb 24 2012) Doppler

To date, two main categories of OCT techniques have been described for imaging hemodynamics: Doppler OCT and OCT angiography. Doppler OCT can measure axial velocity profiles and flow in arteries and veins, while OCT angiography can determine vascular morphology, tone, and presence or absence of red blood cell (RBC) perfusion. However, neither method can quantify RBC velocity in capillaries, where RBC flow is typically transverse to the probe beam and ... (Read Full Article)

Comment Mentions:   Massachusetts Institute of Technology   Thorlabs   Alex E. Cable

Acute Stent Thrombosis: Technical Complication or Inadequate Antithrombotic Therapy?: An Optical Coherence Tomography Study

Explore interventions.onlinejacc.org (Feb 20 2012) Cardiology

No Abstract Provided (Read Full Article)

Comment Mentions:   Massachusetts General Hospital   Ik-Kyung Jang   Harvard University