1. Massachusetts General Hospital

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    1. Mentioned In 699 Articles

    2. Synchronized, concurrent optical coherence tomography and videostroboscopy for monitoring vocal fold morphology and kinematics

      Explore OSA | OSA Publishing Otolaryngology
      Synchronized, concurrent optical coherence tomography and videostroboscopy for monitoring vocal fold morphology and kinematics
      Voice disorders affect a large number of adults in the United States, and their clinical evaluation heavily relies on laryngeal videostroboscopy, which captures the medial-lateral and anterior-posterior motion of the vocal folds using stroboscopic sampling. However, videostroboscopy does not provide direct visualization of the superior-inferior movement of the vocal folds, which yields important clinical insight. In this paper, we present a novel technology that complements videostroboscopic findings by adding the ...
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      Mentions: Massachusetts General Hospital Physical Sciences Incorporated Nicusor Iftimia

    3. Intranasal micro-optical coherence tomography imaging for cystic fibrosis studies

      Explore Science Translational Medicine Pulmonology
      Intranasal micro-optical coherence tomography imaging for cystic fibrosis studies
      Cystic fibrosis (CF) is a genetic disease caused by mutations in the CF transmembrane conductance regulator (CFTR) gene. Although impairment of mucociliary clearance contributes to severe morbidity and mortality in people with CF, a clear understanding of the pathophysiology is lacking. This is, in part, due to the absence of clinical imaging techniques capable of capturing CFTR-dependent functional metrics at the cellular level. Here, we report the clinical translation of ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital University of Alabama

    4. New intra-nasal imaging technique allows researchers to study airways in patients with cystic fibrosis

      Explore Massachusetts General Hospital Home Pulmonology
      New intra-nasal imaging technique allows researchers to study airways in patients with cystic fibrosis
      ...gator for the department of Pathology and Wellman Center for Photomedicine at Massachusetts General Hospital (MGH), the Remondi Family MGH Research Institute Chair, and professor of pathology at Harvard Medical School (H...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    7. Massachusetts General Hospital Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobroncial Optical Coherence Tomography

      Explore Optical Coherence Tomography News Pulmonology , Funding
      Massachusetts General Hospital Receives NIH Grant for Assessing Airway Smooth Muscle Tone in Asthma with Endobroncial Optical Coherence Tomography
      ...sis on optics and signal processing. Since beginning postdoctoral research at Massachusetts General Hospital (MGH), he has worked on developing novel data processing techniques to maximize the utilization of data obtaine...
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      Mentions: Massachusetts General Hospital

    8. Imaging the Human Prostate Gland Using 1-μm-Resolution Optical Coherence Tomography

      Explore archivesofpathology.org Urology
      Imaging the Human Prostate Gland Using 1-μm-Resolution Optical Coherence Tomography
      Context. The accuracy of needle biopsy for the detection of prostate cancer is limited by well-known sampling errors. Thus, there is an unmet need for a microscopic screening tool that can screen large regions of the prostate comprehensively for cancer. Previous prostate imaging by optical coherence tomography (OCT) has had insufficient resolution for imaging cellular features related to prostate cancer. We have recently developed micro-optical coherence tomography (OCT) that generates ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    9. Plaque burden can be assessed using intravascular optical coherence tomography and a dedicated automated processing algorithm: a comparison study with intravascular ultrasound

      Explore Journals Cardiology
      Plaque burden can be assessed using intravascular optical coherence tomography and a dedicated automated processing algorithm: a comparison study with intravascular ultrasound
      Aims Plaque burden (PB) measurement using intravascular optical coherence tomography (IVOCT) is currently thought to be inferior to intravascular ultrasound (IVUS). We developed an automated IVOCT image processing algorithm to enhance the external elastic lamina (EEL) contour. Thus, we investigated the accuracies of standard IVOCT and an IVOCT enhancement algorithm for measuring PB using IVUS as the reference standard. Methods and results The EEL-enhancement algorithm combined adaptive attenuation compensation, exponentiation ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Cardiovascular Research Foundation

    11. Motorized capsule for shadow-free OCT imaging and synchronous beam control

      Explore OSA | OSA Publishing Gastroenterology , Probes
      Motorized capsule for shadow-free OCT imaging and synchronous beam control
      We demonstrate a tethered motorized capsule for unobstructed optical coherence tomography (OCT) imaging of the esophagus. By using a distal reflector design, we avoided the common shadow artifact induced by the motor wires. A synchronous driving technique features three types of beam-scanning modes of the capsule, i.e., circumferential beam scanning, localized beam scanning, and accurate beam positioning. We characterized these three modes and carried out ex vivo imaging experiments ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    16. Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks

      Explore OSA | OSA Publishing Dermatology
      Segmentation of mouse skin layers in optical coherence tomography image data using deep convolutional neural networks
      Optical coherence tomography (OCT) enables the non-invasive acquisition of high-resolution three-dimensional cross-sectional images at micrometer scale and is mainly used in the field of ophthalmology for diagnosis as well as monitoring of eye diseases. Also in other areas, such as dermatology, OCT is already well established. Due to its non-invasive nature, OCT is also employed for research studies involving animal models. Manual evaluation of OCT images of animal models is ...
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      Mentions: Massachusetts General Hospital Gereon Hüttmann University of Lübeck
    17. 1-15 of 699 1 2 3 4 ... 45 46 47 »
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  4. About Massachusetts General Hospital

    Massachusetts General Hospital

    Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center).

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  6. Quotes about Massachusetts General Hospital

    1. We are excited to see the publication of this data from our collaborators at Massachusetts General Hospital that clearly demonstrate the imaging technology can produce valuable images of esophageal tissue...We look forward to moving ahead with continued development of this exciting new technology.
      Charles Carignan in NinePoint Medical Imaging Technology Highlighted in Nature Medicine