1. Massachusetts General Hospital

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    1. Mentioned In 719 Articles

    2. All fiber polarization insensitive detection for spectrometer based optical coherence tomography using optical switch

      Explore OSA | OSA Publishing
      All fiber polarization insensitive detection for spectrometer based optical coherence tomography using optical switch
      Polarization dependent image artifacts are common in optical coherence tomography imaging. Polarization insensitive detection scheme for swept source based optical coherence tomography systems is well established but is yet to be demonstrated for all fiber spectrometer-based Fourier domain optical coherence tomography systems. In this work, we present an all fiber polarization insensitive detection scheme for spectrometer based optical coherence tomography systems. Images from chicken breast muscle tissue were acquired to ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    3. Stable multi-megahertz circular-ranging optical coherence tomography at 1.3 µm

      Explore OSA | OSA Publishing
      Stable multi-megahertz circular-ranging optical coherence tomography at 1.3 µm
      In Fourier-domain optical coherence tomography (OCT), the finite bandwidth of the acquisition electronics constrains the depth range and speed of the system. Circular-ranging (CR) OCT methods use optical-domain compression to surpass this limit. However, the CR-OCT system architectures of prior reports were limited by poor stability and were confined to the 1.55 m wavelength range. In this work, we describe a novel CR-OCT architecture that is free from these ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    5. Capillary Refill—The Key to Assessing Dermal Capillary Capacity and Pathology in Optical Coherence Tomography Angiography

      Explore Wiley Online Library Dermatology
      Capillary Refill—The Key to Assessing Dermal Capillary Capacity and Pathology in Optical Coherence Tomography Angiography
      Background/Objectives: Standard optical coherence tomography angiography (OCTA) has been limited to imaging blood vessels actively undergoing perfusion, providing a temporary picture of surface microvasculature. Capillary perfusion in the skin is dynamic and changes in response to the surrounding tissue's respiratory, nutritional, and thermoregulatory needs. Hence, OCTA often represents a given perfusion state without depicting the actual extent of the vascular network. Here we present a method for obtaining ...
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      Mentions: Massachusetts General Hospital Gereon Hüttmann Reginald Birngruber

    6. Postdoctoral Research Fellowships (In Vivo Microscopy) at the Massachusetts General Hospital

      Explore Optical Coherence Tomography News Jobs & Studentships
      Postdoctoral Research Fellowships (In Vivo Microscopy) at the Massachusetts General Hospital
      ...scopy is available in the Tearney Lab (www.tearneylab.org) at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow at Harvard ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    7. Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hospital

      Explore Optical Coherence Tomography News Jobs & Studentships
      Postdoctoral Research Fellowships (Optical Coherence Tomography) at Massachusetts General Hospital
      ...(OCT) is available in the Tearney Lab (www.tearneylab.org) at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow or instruct...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    8. Intravascular Polarimetry in Patients With Coronary Artery Disease

      Explore ScienceDirect Cardiology
      Intravascular Polarimetry in Patients With Coronary Artery Disease
      Objectives The aims of this first-in-human pilot study of intravascular polarimetry were to investigate polarization properties of coronary plaques in patients and to examine the relationship of these features with established structural characteristics available to conventional optical frequency domain imaging (OFDI) and with clinical presentation. Background Polarization-sensitive OFDI measures birefringence and depolarization of tissue together with conventional cross-sectional optical frequency domain images of subsurface microstructure. Methods Thirty patients undergoing polarization-sensitive ...
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      Mentions: Brett E. Bouma Massachusetts Institute of Technology Leiden University

    10. Intravascular Polarimetry for Tissue Characterization of Coronary Atherosclerosis

      Explore jstage.jst.go.jp Cardiology
      Intravascular Polarimetry for Tissue Characterization of Coronary Atherosclerosis
      The microscopic tissue structure and organization influence the polarization of light. Intravascular polarimetry leverages this compelling intrinsic contrast mechanism by using polarization-sensitive optical frequency domain imaging to measure the polarization properties of the coronary arterial wall. Tissues rich in collagen and smooth muscle cells appear birefringent, while the presence of lipid causes depolarization, offering quantitative metrics related to the presence of important components of coronary atherosclerosis. Here, we review the ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    11. 3D cellular-resolution imaging in arteries using few-mode interferometry

      Explore Nature Publishing Group
      3D cellular-resolution imaging in arteries using few-mode interferometry
      Article Open Access Published: 21 November 2019 3D cellular-resolution imaging in arteries using few-mode interferometry Biwei Yin , Zhonglie Piao , Kensuke Nishimiya , Chulho Hyun , Joseph A. Gardecki , Adam Mauskapf , Farouc A. Jaffer Guillermo J. Tearney Light: Science Applications volume 8 , Article number: 104 ( 2019 ) Cite this article Article metrics 3 Altmetric Metrics details Abstract Cross-sectional visualisation of the cellular and subcellular structures of human atherosclerosis in vivo is significant, as this ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital Harvard University

    12. Excess mucus viscosity and airway dehydration impact COPD airway clearance

      Explore European Respiratory Journal Pulmonology
      Excess mucus viscosity and airway dehydration impact COPD airway clearance
      The mechanisms by which cigarette smoking impairs airway mucus clearance are not well understood. We recently established a ferret model of cigarette smoke-induced chronic obstructive pulmonary disease (COPD) exhibiting chronic bronchitis. We investigated the effects of cigarette smoke on mucociliary transport (MCT). Adult ferrets were exposed to cigarette smoke for 6 months, with in vivo mucociliary clearance (MCC) measured by Tc-labeled DTPA (Tc-DTPA) retention. Excised tracheae were imaged with micro-optical ...
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      Mentions: Guillermo J. Tearney Johns Hopkins University Massachusetts General Hospital

    13. Highly-stable, multi-megahertz circular-ranging optical coherence tomography at 1.3 µm based on a chirped fiber Bragg grating

      Explore arxiv.org Tunable Sources
      Highly-stable, multi-megahertz circular-ranging optical coherence tomography at 1.3 µm based on a chirped fiber Bragg grating
      In Fourier-domain optical coherence tomography (OCT), the finite bandwidth of the acquisition electronics constrains the depth range and speed of the system. Circular-ranging (CR) OCT methods use optical-domain compression to surpass this limit. However, the CR-OCT system architectures of prior reports were limited by poor stability and were confined to the 1.55 m wavelength range. In this work, we describe a novel CR-OCT architecture that is free from these ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Harvard University

    14. Cardiovascular OCT Imaging (Textbook)

      Explore Home - Springer Cardiology , Textbooks
      Cardiovascular OCT Imaging (Textbook)
      This heavily revised second edition comprehensively reviews the use of optical coherence tomography (OCT) in cardiovascular practice. It provides detailed guidance on how to properly interpret OCT images and successfully utilise it in daily clinical practice Chapters cover the development and physics associated with OCT, relevant interpretation skills, OCT imaging artifacts, plaque erosion, bioabsorbable stent, the detection of vulnerable plaque, and the use of OCT imaging in unison with other ...
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      Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University

    15. Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging

      Explore OSA | OSA Publishing Pulmonology
      Co-cultured microfluidic model of the airway optimized for microscopy and micro-optical coherence tomography imaging
      We have developed a human bronchial epithelial (HBE) cell and endothelial cell co-cultured microfluidic model to mimic the in vivo human airway. This airway-on-a-chip was designed with a central epithelial channel and two flanking endothelial channels, with a three-dimensional monolayers of cells growing along the four walls of the channel, forming central clear lumens. These cultures mimic airways and microvasculature in vivo . The central channel cells are grown at air-liquid ...
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      Mentions: Guillermo J. Tearney Massachusetts General Hospital University of Alabama

    16. Constrained polarization evolution simplifies depth-resolved retardation measurements with polarization-sensitive optical coherence tomography

      Explore OSA | OSA Publishing
      Constrained polarization evolution simplifies depth-resolved retardation measurements with polarization-sensitive optical coherence tomography
      We observed that the polarization state of light after round-trip propagation through a birefringent medium frequently aligns with the employed input polarization state mirrored by the horizontal plane of the Poincar sphere. We explored the predisposition for this mirror state and evidence that it constrains the evolution of polarization states as a function of the round-trip depth into weakly scattering birefringent samples, as measured with polarization-sensitive optical coherence tomography (PS-OCT ...
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      Mentions: Brett E. Bouma Massachusetts General Hospital Singapore Eye Research Institute
    17. 1-15 of 719 1 2 3 4 ... 46 47 48 »
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  4. About Massachusetts General Hospital

    Massachusetts General Hospital

    Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center).

  5. Related Topics

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      93 articles also mentioned Massachusetts Institute of Technology
    4. High-speed polarization sensitive optical frequency domain imaging with frequency multiplexing
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    5. 1st Massachusetts General Hospital OCT Registry Symposium Scheduled for March 13, 2010
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  6. Quotes about Massachusetts General Hospital

    1. We are excited to see the publication of this data from our collaborators at Massachusetts General Hospital that clearly demonstrate the imaging technology can produce valuable images of esophageal tissue...We look forward to moving ahead with continued development of this exciting new technology.
      Charles Carignan in NinePoint Medical Imaging Technology Highlighted in Nature Medicine