1. Massachusetts General Hospital

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    1. Mentioned In 679 Articles

    2. Retinal Blood Vessel Caliber Estimation for Optical Coherence Tomography Angiography Images Based on 3D Superellipsoid Modeling

      Retinal Blood Vessel Caliber Estimation for Optical Coherence Tomography Angiography Images Based on 3D Superellipsoid Modeling
      Changes of retinal blood vessel calibers may reflect various retinal diseases and even several non-retinal diseases. We propose a new method to estimate retinal vessel calibers from 3D optical coherence tomography angiography (OCTA) images based on 3D modeling using superellipsoids. Taking advantage of 3D visualization of the retinal tissue microstructures in vivo provided by OCTA, our method can detect retinal blood vessels precisely, estimate their calibers reliably, and show the ...
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    3. Healed Culprit Plaques in Patients With Acute Coronary Syndrome

      Healed Culprit Plaques in Patients With Acute Coronary Syndrome
      ackground Healed plaques, morphologically characterized by a layered phenotype, are frequently found in subjects with sudden cardiac death. However, in vivo data are lacking. Objectives The purpose of this study was to determine the prevalence, morphological characteristics, and clinical significance of healed culprit plaques in patients with acute coronary syndromes (ACS) using optical coherence tomography (OCT). Methods A total of 376 ACS patients (252 ST-segment elevation myocardial infarction [MI] and ...
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    4. Optimization-based vessel segmentation pipeline for robust quantification of capillary networks in skin with optical coherence tomography angiography

      Optimization-based vessel segmentation pipeline for robust quantification of capillary networks in skin with optical coherence tomography angiography
      Optical coherence tomography angiography (OCTA) provides in-vivo images of microvascular perfusion in high resolution. For its application to basic and clinical research, an automatic and robust quantification of the capillary architecture is mandatory. Only this makes it possible to reliably analyze large amounts of image data, to establish biomarkers, and to monitor disease developments. However, due to its optical properties, OCTA images of skin often suffer from a poor signal-to-noise ...
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    5. Balloon catheter-based radiofrequency ablation monitoring in porcine esophagus using optical coherence tomography

      Balloon catheter-based radiofrequency ablation monitoring in porcine esophagus using optical coherence tomography
      We present a microscopic image guidance platform for radiofrequency ablation (RFA) using a clinical balloon-catheter-based optical coherence tomography (OCT) system, currently used in the surveillance of Barretts esophagus patients. Our integrated thermal therapy delivery and monitoring platform consists of a flexible, customized bipolar RFA electrode array designed for use with a clinical balloon OCT catheter and a processing algorithm to accurately map the thermal coagulation process. Non-uniform rotation distortion was ...
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    6. Toward optical coherence tomography angiography-based biomarkers to assess the safety of peripheral nerve electrostimulation

      Toward optical coherence tomography angiography-based biomarkers to assess the safety of peripheral nerve electrostimulation
      Objective: Peripheral nerves serve as a link between the central nervous system and its targets. Altering peripheral nerve activity through targeted electrical stimulation is being investigated as a therapy for modulating end organ function. To support rapid advancement in the field, novel approaches to predict and prevent nerve injury resulting from the electrical stimulation must be developed to overcome the limitations of traditional histological methods. The present study aims to ...
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    7. Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures

      Methods, systems, arrangements and computer-accessible medium for providing micro-optical coherence tomography procedures
      Exemplary apparatus and method can be provided for obtaining data regarding a plurality of samples. For example, using at least one arrangement, it is possible to receive interferometric information that is based on radiations provided from a reference and the samples that are provided in respective chambers. Alternatively and/or in addition, based on the interferometric information, it is possible to discriminate between agents to identify a particular agent that ...
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    8. Angiographic features of patients with coronary plaque erosion

      Angiographic features of patients with coronary plaque erosion
      Background Although an in vivo diagnosis of coronary plaque erosion has become possible by optical coherence tomography (OCT), angiographic characteristics of erosion have not been studied. The aim of this study was to investigate the angiographic features of plaque erosion in patients with non-ST elevation acute coronary syndromes (NSTE-ACS). Methods Patients with NSTE-ACS who underwent OCT of the culprit lesion were collected at 11 institutions from 6 countries. Patients were ...
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    9. Coronary Atherosclerotic Phenotype and Plaque Healing in Patients With Recurrent Acute Coronary Syndromes Compared With Patients With Long-term Clinical Stability An In Vivo Optical Coherence Tomography Study

      Coronary Atherosclerotic Phenotype and Plaque Healing in Patients With Recurrent Acute Coronary Syndromes Compared With Patients With Long-term Clinical Stability An In Vivo Optical Coherence Tomography Study
      Importance At one end of the coronary artery disease (CAD) spectrum, there are patients with multiple recurrent acute coronary syndromes (rACS), and at the other end there are those with long-standing clinical stability. Predicting the natural history of these patients is challenging because unstable plaques often heal without resulting in ACS. Objective To assess in vivo the coronary atherosclerotic phenotype as well as the prevalence and characteristics of healed coronary ...
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    10. Optical coherence tomography-guided laser marking with tethered capsule endomicroscopy in unsedated patients

      Optical coherence tomography-guided laser marking with tethered capsule endomicroscopy in unsedated patients
      Tethered capsule endomicroscopy (TCE) is an emerging screening technology that comprehensively obtains microstructural OCT images of the gastrointestinal (GI) tract in unsedated patients. To advance clinical adoption of this imaging technique, it will be important to validate TCE images with co-localized histology, the current diagnostic gold standard. One method for co-localizing OCT images with histology is image-targeted laser marking, which has previously been implemented using a driveshaft-based, balloon OCT catheter ...
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    11. Postdoctoral Research Fellowships in Optical Coherence Tomography at The Tearney Lab at the Wellman Center for Photomedicine at the Massachusetts General Hospital Boston, MA USA

      Postdoctoral Research Fellowships in Optical Coherence Tomography at The Tearney Lab at the Wellman Center for Photomedicine at the Massachusetts General Hospital Boston, MA USA
      ... of optical coherence tomography (OCT) is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow...
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    12. Postdoctoral Research Fellowship Opening in In Vivo Microscopy at the Wellman Center for Photomedicine at the Massachusetts General Hospital, Boston USA

      Postdoctoral Research Fellowship Opening in In Vivo Microscopy at the Wellman Center for Photomedicine at the Massachusetts General Hospital, Boston USA
      ...ship in the area of In Vivo Microscopy is available in the Tearney Lab at the Massachusetts General Hospital (MGH) in the Wellman Center for Photomedicine. This appointment will be made at the rank of postdoctoral fellow...
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    13. 1-15 of 679 1 2 3 4 ... 44 45 46 »
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  2. About Massachusetts General Hospital

    Massachusetts General Hospital

    Massachusetts General Hospital is a teaching hospital of Harvard Medical School and biomedical research facility in Boston, Massachusetts. It is owned and operated by Partners HealthCare (which also owns Brigham and Women's Hospital and North Shore Medical Center).

  3. Quotes about Massachusetts General Hospital

    1. We are excited to see the publication of this data from our collaborators at Massachusetts General Hospital that clearly demonstrate the imaging technology can produce valuable images of esophageal tissue...We look forward to moving ahead with continued development of this exciting new technology.
      Charles Carignan in NinePoint Medical Imaging Technology Highlighted in Nature Medicine