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    1. Mentioned In 89 Articles

    2. Optical coherence tomographic angiography identifies peripapillary microvascular dilation and focal non-perfusion in giant cell arteritis

      Optical coherence tomographic angiography identifies peripapillary microvascular dilation and focal non-perfusion in giant cell arteritis
      Aims We set out to determine the optical coherence tomographic angiography (OCT-A) characteristics of arteritic anterior ischaemic optic neuropathy (AAION) in the context of giant cell arteritis (GCA). Methods This is an observational case series of four patients with AAION secondary to GCA, three with unilateral AAION and one with bilateral AAION. We reviewed the charts, fundus photography, visual fields, fluorescein angiography (FA) and OCT-A images for all patients to ...
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    3. Optical coherence tomography findings and successful repair of retina detachment in Knobloch syndrome

      Optical coherence tomography findings and successful repair of retina detachment in Knobloch syndrome
      A 7-year-old Afghani girl was referred to the retina clinic of Massachusetts Eye and Ear for a chronic-appearing, macula-off retinal detachment in the left eye. On examination, best-corrected visual acuity was 20/400 in the right eye and 20/800 in the left eye. She had bilateral horizontal nystagmus. Ophthalmoscopy revealed prominent choroidal vessels, chorioretinal atrophy in the macular area, attenuated retinal vasculature, and pale optic discs bilaterally. Spectral domain ...
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    4. Congenital anomalies of the optic disc: insights from optical coherence tomography imaging

      Congenital anomalies of the optic disc: insights from optical coherence tomography imaging
      Purpose of review Congenital anomalies of the optic nerve are rare but significant causes of visual dysfunction in children and adults. Accurate diagnosis is dependent on a thorough funduscopic examination, but can be enhanced by imaging information garnered from optical coherence tomography (OCT). We review common congenital optic nerve anomalies, including optic disc pit, optic nerve coloboma, morning glory disc anomaly, and hypoplasia of the optic nerve, review their systemic ...
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    5. Volumetric Measurement of Optic Nerve Head Drusen Using Swept-Source Optical Coherence Tomography

      Volumetric Measurement of Optic Nerve Head Drusen Using Swept-Source Optical Coherence Tomography
      Purpose: To describe new software tools for quantifying optic nerve head drusen volume using 3-dimensional (3D) swept-source optical coherence tomography (SS-OCT) volumetric scans. Materials and Methods: SS-OCT was used to acquire raster volume scans of 8 eyes of 4 patients with bilateral optic nerve head drusen. The scans were manually segmented by 3 graders to identify the drusen borders, and thereafter total drusen volumes were calculated. Linear regression was performed ...
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    6. Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography

      Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography
      A 50-year-old woman with a history of rheumatoid arthritis and macular hydroxychloroquine toxicity presented for a routine eye examination. An incidental loop vessel of the inferior prepapillary arteriole was readily apparent on examination (Fig 1 A ). Three-dimensional optical coherence tomography (OCT; Avanti, Optovue, Fremont, CA) demonstrated the elevation of this vessel into the vitreous (Fig 1 B ). The vessel was also captured on OCT-angiography (Fig 1 C ) with segmentation of ...
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    7. Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography

      Retinal Loop Vessel Captured with Optical Coherence Tomography-Angiography
      A 50-year-old woman with a history of rheumatoid arthritis and macular hydroxychloroquine toxicity presented for a routine eye examination. An incidental loop vessel of the inferior prepapillary arteriole was readily apparent on examination (Fig 1 A ). Three-dimensional optical coherence tomography (OCT; Avanti, Optovue, Fremont, CA) demonstrated the elevation of this vessel into the vitreous (Fig 1 B ). The vessel was also captured on OCT-angiography (Fig 1 C ) with segmentation of ...
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    8. Focal Capillary Dropout Associated With Optic Disc Drusen Using Optical Coherence Tomographic Angiography

      Focal Capillary Dropout Associated With Optic Disc Drusen Using Optical Coherence Tomographic Angiography
      Optic disc drusen may be a cause of visual field defects and visual loss. The mechanism by which this occurs is unclear. We report a patient who developed decreased vision in the right eye and was found to have a heavy burden of superficial optic disc drusen. Optical coherence tomography (OCT) confirmed focal retinal nerve fiber layer thinning that corresponded with the distribution of drusen. OCT angiography, with superficial laminar ...
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    9. Anterior segment optical coherence tomography to look for Kayser-Fleischer rings

      Anterior segment optical coherence tomography to look for Kayser-Fleischer rings
      Ophthalmologists usually use slit lamp biomicroscopy to look for Kayser-Fleischer rings in Wilsons disease; anterior segment optical coherence tomography is a new alternative to identify the characteristic hyper-reflective layer in the deep corneal periphery at the level of Descemets membrane. This method allows non-ophthalmologists to look for and to quantify Kayser-Fleischer rings.
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    10. Enhanced Diagnostic Capability for Glaucoma of 3-Dimensional Versus 2-Dimensional Neuroretinal Rim Parameters Using Spectral Domain Optical Coherence Tomography

      Enhanced Diagnostic Capability for Glaucoma of 3-Dimensional Versus 2-Dimensional Neuroretinal Rim Parameters Using Spectral Domain Optical Coherence Tomography
      Purpose: To compare the diagnostic capability of 3-dimensional (3D) neuroretinal rim parameters with existing 2-dimensional (2D) neuroretinal and retinal nerve fiber layer (RNFL) thickness rim parameters using spectral domain optical coherence tomography (SD-OCT) volume scans. Materials and Methods: Design: Institutional prospective pilot study. Study population: 65 subjects (35 open-angle glaucoma patients, 30 normal patients). Observation procedures: One eye of each subject was included. SD-OCT was used to obtain 2D RNFL ...
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    11. CHOROIDAL THICKNESS IN DIABETIC RETINOPATHY ASSESSED WITH SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY

      CHOROIDAL THICKNESS IN DIABETIC RETINOPATHY ASSESSED WITH SWEPT-SOURCE OPTICAL COHERENCE TOMOGRAPHY
      Purpose: To compare the choroidal thickness (CT) of diabetic eyes (different stages of disease) with controls, using swept-source optical coherence tomography. Methods: A multicenter, prospective, cross-sectional study of diabetic and nondiabetic subjects using swept-source optical coherence tomography imaging. Choroidal thickness maps, according to the nine Early Treatment Diabetic Retinopathy Study (ETDRS) subfields, were obtained using automated software. Mean CT was calculated as the mean value within the ETDRS grid, and ...
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    12. In vivo 3D imaging of the human tympanic membrane using a wide-field diagonal-scanning optical coherence tomography probe

      In vivo 3D imaging of the human tympanic membrane using a wide-field diagonal-scanning optical coherence tomography probe
      A wide-field optical coherence tomography (OCT) probe was developed that adapts a diagonal-scanning scheme for three-dimensional (3D) in vivo imaging of the human tympanic membrane. The probe consists of a relay lens to enhance the lateral scanning range up to 7 mm. Motion artifacts that occur with the use of handheld probes were found to be decreased owing to the diagonal-scanning pattern, which crosses the center of the sample to ...
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    13. Optical Coherence Tomography Angiography of Paracentral Acute Middle Maculopathy Associated With Primary Antiphospholipid Syndrome

      Optical Coherence Tomography Angiography of Paracentral Acute Middle Maculopathy Associated With Primary Antiphospholipid Syndrome
      The authors present the first case of paracentral acute middle maculopathy as a manifestation of primary antiphospholipid syndrome (APS) with multimodal imaging, including optical coherence tomography angiography (OCTA). The association between APS and ophthalmic sequela is well-known. Recent advances in multimodal imaging, specifically OCTA, allow for better characterization of the mechanism and extent by which retinal arterial thrombosis can cause vision loss. Using advanced imaging modalities, the authors provide a ...
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    14. Bio-Photonic Detection and Quantitative Evaluation Method for the Progression of Dental Caries Using Optical Frequency-Domain Imaging Method

      Bio-Photonic Detection and Quantitative Evaluation Method for the Progression of Dental Caries Using Optical Frequency-Domain Imaging Method
      The initial detection of dental caries is an essential biomedical requirement to barricade the progression of caries and tooth demineralization. The objective of this study is to introduce an optical frequency-domain imaging technique based quantitative evaluation method to calculate the volume and thickness of enamel residual, and a quantification method was developed to evaluate the total intensity fluctuation in depth direction owing to carious lesions, which can be favorable to ...
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    15. Comprehensive Three-Dimensional Analysis of the Neuroretinal Rim in Glaucoma Using High-Density Spectral-Domain Optical Coherence Tomography Volume Scans

      Comprehensive Three-Dimensional Analysis of the Neuroretinal Rim in Glaucoma Using High-Density Spectral-Domain Optical Coherence Tomography Volume Scans
      Purpose : To describe spectral-domain optical coherence tomography (OCT) methods for quantifying neuroretinal rim tissue in glaucoma and to compare these methods to the traditional retinal nerve fiber layer thickness diagnostic parameter. Methods : Neuroretinal rim parameters derived from three-dimensional (3D) volume scans were compared with the two-dimensional (2D) Spectralis retinal nerve fiber layer (RNFL) thickness scans for diagnostic capability. This study analyzed one eye per patient of 104 glaucoma patients and ...
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    16. Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography

      Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography
      Purpose To present in vivo anterior segment optical coherence tomography (OCT) features of infants with Peters' anomaly obtained during presurgical examination under general anaesthesia, and to evaluate the impact of OCT features on surgical decision making. Methods This is a single-centre, consecutive, observational case series including 44 eyes of 27 infants with Peters' anomaly (518 months) undergoing keratoplasty. Medical records of patients were reviewed retrospectively. Clinical features and OCT findings ...
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  2. About Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary is a specialty hospital providing outstanding patient care for disorders of the eye, ear, nose, throat, head and neck. Founded in 1824, MEEI is an international leader in Ophthalmology and Otolaryngology research and a teaching partner of Harvard Medical School.