1. Massachusetts Eye and Ear Infirmary

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    1. Mentioned In 53 Articles

    2. Fully automated detection of diabetic macular edema and dry age-related macular degeneration from optical coherence tomography images

      Fully automated detection of diabetic macular edema and dry age-related macular degeneration from optical coherence tomography images
      ...A ^2Department of Computer Science, Duke University, Durham 27708, USA ^3Schepens Eye Research Institute, Massachusetts Eye and Ear Infirmary, Harvard University, Boston, 02114, USA ^4Department of Ophthalmology, D...
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    3. Corneal perforation by an astigmatic keratotomy performed with an optical coherence tomography–guided femtosecond laser

      Corneal perforation by an astigmatic keratotomy performed with an optical coherence tomography–guided femtosecond laser

      We present a case of corneal perforation secondary to an intrastromal astigmatic keratotomy performed with an optical coherence tomography–guided femtosecond laser. The keratotomy was concomitant with cataract surgery and resulted in a flat anterior chamber prior to the start of lens extraction. Interrupted nylon sutures were placed to seal the keratotomy prior to phacoemulsification. Escape of cavitation bubbles into the anterior chamber or the liquid interface can alert the surgeon to the possibility of unintended perforation of the endothelium or the epithelium, respectively.

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    4. Facilitating Glaucoma Diagnosis With Intereye Retinal Nerve Fiber Layer Asymmetry Using Spectral-Domain Optical Coherence Tomography

      Facilitating Glaucoma Diagnosis With Intereye Retinal Nerve Fiber Layer Asymmetry Using Spectral-Domain Optical Coherence Tomography
      ...s: Sixty-six primary open-angle glaucoma (OAG) and 40 age-matched normal subjects had both eyes imaged at the Massachusetts Eye and Ear Infirmary with a commercially available spectral-domain optical coherence tomography...
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    5. Vitreous Hyper-Reflective Dots in Optical Coherence Tomography and Cystoid Macular Edema after Uneventful Phacoemulsification Surgery

      Vitreous Hyper-Reflective Dots in Optical Coherence Tomography and Cystoid Macular Edema after Uneventful Phacoemulsification Surgery

      Purpose To report the observation of hyper-reflective dots in the vitreous cavity using spectral domain optical coherence tomography (SD-OCT) after uneventful phacoemulsification cataract surgery and to investigate their association with cystoid macular edema (CME). Materials and Methods Medical records of consecutive Asian patients who had no preoperative retinopathy and underwent uneventful phacoemulsification cataract surgery from March 2012 through February 2013 were reviewed. SD-OCTs were performed before, 1 week, and 1 month after surgery. The number of vitreous hyper-reflective dots (VHDs) was counted in 5 OCT images of high-definition 5-line raster scans. The development of CME was assessed using postoperative 1-month ...

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    6. Physical Sciences Receives NIH Grant for A Functional Otoscopy for Non-Invasive Diagnosis of Middle Ear

      Physical Sciences Receives NIH Grant for A Functional Otoscopy for Non-Invasive Diagnosis of Middle Ear
      ... Sciences Inc. (PSI), in collaboration with the Eaton Peabody Lab at the Massachusetts Eye and Ear Infirmary (MEEI), will develop a clinically viable otoscopic imaging system that will employ phase sensitive optical cohe...
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    7. Macula and Retinal Nerve Fiber Layer in Migraine Patients: Analysis By Spectral Domain Optic Coherence Tomography

      Macula and Retinal Nerve Fiber Layer in Migraine Patients: Analysis By Spectral Domain Optic Coherence Tomography

      Aim : Investigating the retinal nerve fiber layer (RNFL), macular and ganglion cell complex thickness in eyes of migraine patients using optical coherence tomography. Methods : The study was designed as an observational cross-sectional study. 50 patients with migraine (30 patients with aura and 20 patients without aura) and 50 healthy volunteers were included. Optical coherence tomography was performed with Optovue technology. The fast RNFL thickness (3.4) scan, MM5, and GCC acquisition protocols were used. Results : There was no statistically significant difference in retinal thickness in any of the quadrants between the control group and the migraine patients ( p  > 0.05 ...

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    8. Evaluation of the Anterior Chamber Angle in Glaucoma: A Report by the American Academy of Ophthalmology

      Evaluation of the Anterior Chamber Angle in Glaucoma: A Report by the American Academy of Ophthalmology

      Objective To assess the published literature pertaining to the association between anterior segment imaging and gonioscopy and to determine whether such imaging aids in the diagnosis of primary angle closure (PAC). Methods Literature searches of the PubMed and Cochrane Library databases were last conducted on July 6, 2011. The searches yielded 371 unique citations. Members of the Ophthalmic Technology Assessment Committee Glaucoma Panel reviewed the titles and abstracts of these articles and selected 134 of possible clinical significance for further review. The panel reviewed the full text of these articles and identified 79 studies meeting the inclusion criteria, for which ...

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    9. Optical coherence tomography imaging during thyroid and parathyroid surgery: A novel system of tissue identification and differentiation to obviate tissue resection and frozen section

      Optical coherence tomography imaging during thyroid and parathyroid surgery: A novel system of tissue identification and differentiation to obviate tissue resection and frozen section
      ... 243 Charles Street, Boston, MA 02114 - 3002, Phone: 617-573-4115, Fax: 617-573-3914, Email: gregory_randolph@meei.harvard.edu NIH. Grant Number: R01 CA103769 CAPES (Coordination for the Improvement of Higher Level – o...
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    10. Simultaneous 3D imaging of sound-induced motions of the tympanic membrane and middle ear ossicles

      Simultaneous 3D imaging of sound-induced motions of the tympanic membrane and middle ear ossicles

      Efficient transfer of sound by the middle ear ossicles is essential for hearing. Various pathologies can impede the transmission of sound and thereby cause conductive hearing loss. Differential diagnosis of ossicular disorders can be challenging since the ossicles are normally hidden behind the tympanic membrane (TM). Here we describe the use of a technique termed optical coherence tomography (OCT) vibrography to view the sound-induced motion of the TM and ossicles simultaneously. With this method, we were able to capture three-dimensional motion of the intact TM and ossicles of the chinchilla ear with nanometer-scale sensitivity at sound frequencies from 0.5 ...

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    11. Quantitative polarized light microscopy of unstained mammalian cochlear sections

      Quantitative polarized light microscopy of unstained mammalian cochlear sections
      ...arvard Medical School, Department of Otology and Laryngology, 25 Shattuck Street, Boston, Massachusetts 02115 Massachusetts Eye and Ear Infirmary, Department of Otolaryngology, 243 Charles Street, Boston, Massachusetts 0...
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  2. About Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary is a specialty hospital providing outstanding patient care for disorders of the eye, ear, nose, throat, head and neck. Founded in 1824, MEEI is an international leader in Ophthalmology and Otolaryngology research and a teaching partner of Harvard Medical School.