1. Massachusetts Eye and Ear Infirmary

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    1. Mentioned In 160 Articles

    2. MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emissions

      MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emissions
      ...t can be validated using non-invasive hearing-threshold and OAE measurements.

      Massachusetts Eye and Ear Infirmary Received a 2022 NIH Grant for $117,133 for Measuring and Modeling the Coch...

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    3. Juxtapapillary Choroidal Neovascular Membrane as a Complication of Optic Disc Drusen: Multimodal Imaging With Swept Source-Optical Coherence Tomography and Optical Coherence Tomography Angiography

      Juxtapapillary Choroidal Neovascular Membrane as a Complication of Optic Disc Drusen: Multimodal Imaging With Swept Source-Optical Coherence Tomography and Optical Coherence Tomography Angiography
      A 55-year-old Caucasian man presented to the neuro-ophthalmology department for follow-up evaluation due to long-standing bilateral optic nerve head drusen (ONHD). On examination, the BCVA was 20/20-2 in both eyes. Dilated fundus examination revealed extensive ONHD in both eyes, retinal hemorrhages, exudates inferonasal to the macula, and macular edema inferotemporal to the disc margin. Automated visual field testing revealed generalized depression in both eyes. Late phase leakage was observed ...
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    4. Cochlear Fluid Spaces and Structures of the Gerbil High-Frequency Region Measured Using Optical Coherence Tomography (OCT)

      Cochlear Fluid Spaces and Structures of the Gerbil High-Frequency Region Measured Using Optical Coherence Tomography (OCT)
      Since it has been difficult to directly observe the morphology of the living cochlea, our ability to infer the mechanical functioning of the living ear has been limited. Nearly all our knowledge about cochlear morphology comes from postmortem tissue that was fixed and processed using procedures that possibly distort the structures and fluid spaces of the organ of Corti. In this study, optical coherence tomography was employed to obtain volumetric ...
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    5. MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emission

      MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emission
      ...t can be validated using non-invasive hearing-threshold and OAE measurements.

      Massachusetts Eye and Ear Infirmary Received a 2022 NIH Grant for $488,619 for Measuring and Modeling the Coch...

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    6. New views on three-dimensional imaging technologies for glaucoma: an overview

      New views on three-dimensional imaging technologies for glaucoma: an overview
      Purpose of review To summarize the literature on three-dimensional (3D) technological advances in ophthalmology, the quantitative methods associated with this, and their improved ability to help detect glaucoma disease progression. Recent findings Improvements in measuring glaucomatous structural changes are the result of dual innovations in optical coherence tomography (OCT) imaging technology and in associated quantitative software. Summary Compared with two-dimensional (2D) OCT parameters, newer 3D parameters provide more data and ...
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    7. Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter

      Endomicroscopy of the human cochlea using a micro-optical coherence tomography catheter
      Sensorineural hearing loss (SNHL) is one of the most profound public health concerns of the modern era, affecting 466 million people today, and projected to affect 900 million by the year 2050. Advances in both diagnostics and therapeutics for SNHL have been impeded by the human cochlea's inaccessibility for in vivo imaging, resulting from its extremely small size, convoluted coiled configuration, fragility, and deep encasement in dense bone. Here ...
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    8. Ophthalmic manifestations of dementing disorders

      Ophthalmic manifestations of dementing disorders
      Purpose of review Dementia is a term for loss of memory, language, problem-solving, and other thinking abilities, which significantly interferes with daily life. Certain dementing conditions may also affect visual function. The eye is an accessible window to the brain that can provide valuable information for the early diagnosis of people who suffer from Alzheimer's disease, Parkinson's disease , dementia with Lewy bodies as well as from more rare ...
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    9. Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia

      Wide-field swept-source optical coherence tomography angiography in the assessment of retinal microvasculature and choroidal thickness in patients with myopia
      Background/aims: Pathological myopia (PM) is a leading cause of blindness worldwide. We aimed to evaluate microvascular and chorioretinal changes in different stages of myopia with wide-field (WF) swept-source (SS) optical coherence tomography angiography (OCTA). Methods: This prospective cross-sectional observational study included 186 eyes of 122 patients who had undergone imaging between November 2018 and October 2020. Vessel density (VD) and vessel skeletonised density (VSD) of superficial capillary plexus, deep ...
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    10. Inter-device reliability of swept source and spectral domain optical coherence tomography and retinal layer differences in schizophrenia

      Inter-device reliability of swept source and spectral domain optical coherence tomography and retinal layer differences in schizophrenia
      Introduction Optical coherence tomography (OCT) is used to study retinal structure in schizophrenia. Changes in retinal structure, especially the retinal nerve fiber layer (RNFL) has been correlated with psychotic disorders. Measurement variability is a concern since there are various generations of OCT devices. We investigated the inter- and intra-device agreement of macular thickness between spectral domain (SDOCT) and swept sourceOCT (SSOCT), and compared macula and peripapillary group differences in schizophrenia ...
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    11. Structure-Function Mapping Using a Three-Dimensional Neuroretinal Rim Parameter Derived From Spectral Domain Optical Coherence Tomography Volume Scans

      Structure-Function Mapping Using a Three-Dimensional Neuroretinal Rim Parameter Derived From Spectral Domain Optical Coherence Tomography Volume Scans
      Purpose: To assess the structure-function relationship in glaucoma using Humphrey visual field (HVF) perimetry and a three-dimensional neuroretinal rim parameter derived from spectral domain optical coherence tomography (SD-OCT) volume scans. Methods: Structure-function correlation was analyzed globally and regionally (four quadrants and four sectors). Structural data included peripapillary retinal nerve fiber layer (RNFL) thickness and minimum distance band (MDB) neuroretinal rim thickness, defined as the shortest distance between the inner cup ...
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    12. Watching Death in the Gerbil Cochlea Using Optical Coherence Tomography (OCT)

      Watching Death in the Gerbil Cochlea Using Optical Coherence Tomography (OCT)
      Because it is difficult to directly observe the morphology of the living cochlea, our ability to infer the mechanical functioning of the living ear has been limited. Nearly all of our knowledge about cochlear morphology comes from postmortem tissue that was fixed and processed using procedures that possibly distort the structures and fluid spaces of the organ of Corti. In this study, optical coherence tomography was employed to obtain in ...
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    13. Earlier Detection of Glaucoma Progression Using High-Density 3D Spectral-Domain Optical Coherence Tomography Optic Nerve Volume Scans

      Earlier Detection of Glaucoma Progression Using High-Density 3D Spectral-Domain Optical Coherence Tomography Optic Nerve Volume Scans
      Purpose: To compare onset times of glaucoma progression among different glaucoma tests: disc photography (DP), visual field (VF) testing, two-dimensional (2D) retinal nerve fiber layer (RNFL) thickness, and three-dimensional (3D) spectral-domain optical coherence tomography (SD-OCT) neuroretinal rim measurements. Design: Prospective longitudinal cohort study PARTICIPANTS: One hundred and twenty-four eyes of 124 open angle glaucoma patients METHODS: Over a 5-year period, 124 open angle glaucoma patients had yearly DP, VFs, SD-OCT ...
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    14. Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA)

      Retinal applications of swept source optical coherence tomography (OCT) and optical coherence tomography angiography (OCTA)
      The advent of optical coherence tomography (OCT) revolutionized both clinical assessment and research of vitreoretinal conditions. Since then, extraordinary advances have been made in this imaging technology, including the relatively recent development of swept-source OCT (SS-OCT). SS-OCT enables a fast scan rate and utilizes a tunable swept laser at longer wavelengths than conventional spectral-domain devices. These features enable imaging of larger areas with reduced motion artifact, and a better visualization ...
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  2. About Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary is a specialty hospital providing outstanding patient care for disorders of the eye, ear, nose, throat, head and neck. Founded in 1824, MEEI is an international leader in Ophthalmology and Otolaryngology research and a teaching partner of Harvard Medical School.