1. Massachusetts Eye and Ear Infirmary

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    1. Mentioned In 134 Articles

    2. Comparison of widefield swept-source optical coherence tomography angiography with ultra-widefield colour fundus photography and fluorescein angiography for detection of lesions in diabetic retinopathy

      Comparison of widefield swept-source optical coherence tomography angiography with ultra-widefield colour fundus photography and fluorescein angiography for detection of lesions in diabetic retinopathy
      Aims To compare widefield swept-source optical coherence tomography angiography (WF SS-OCTA) with ultra-widefield colour fundus photography (UWF CFP) and fluorescein angiography (UWF FA) for detecting diabetic retinopathy (DR) lesions. Methods This prospective, observational study was conducted at Massachusetts Eye and Ear from December 2018 to October 2019. Proliferative DR, non-proliferative DR and diabetic patients with no DR were included. All patients were imaged with a WF SS-OCTA using a Montage ...
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    3. Retinal Microvasculature Changes After Repair of Macula-off Retinal Detachment Assessed with Optical Coherence Tomography Angiography

      Retinal Microvasculature Changes After Repair of Macula-off Retinal Detachment Assessed with Optical Coherence Tomography Angiography
      ...edical School, 243 Charles St, Boston, MA 02114 Tel +1 (617) 573-3750 Fax +1 (617) 573-3698 Email john_miller@meei.harvard.edu Objective: To characterize the microvascular retinal changes after repair of macula-off rhegm...
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    4. Future Directions of Optical Coherence Tomography in Otology: A Morphological and Functional Approach

      Future Directions of Optical Coherence Tomography in Otology: A Morphological and Functional Approach
      Optical coherence tomography (OCT) is a real-time optical imaging modality that enables tomographic imaging at the submicron scale. Basic research into applications of OCT systems in the field of otology has been conducted. For instance, Oh et al. [1] recently reported that OCT provided noninvasive, nondestructive two-dimensional cross-sectional and three-dimensional volumetric images of middle-ear and inner ear structures in rodents. Anatomical depth-resolved imaging has shown promising potential for morphological measurements ...
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    5. Monitoring Glaucoma Progression with OCT

      Monitoring Glaucoma Progression with OCT
      Since glaucoma is a progressive disease, physicians are constantly searching for reliable tools to monitor it over time. Before the introduction of optical coherence tomography, determination of glaucoma progression relied heavily on clinical assessment of the optic nerve, comparison of disc photos over time and visual field analysis. Although these remain key elements of the glaucoma evaluation, theyre still subjective and qualitative in nature, limiting their ability to detect progression ...
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    6. Age-Related Macular Degeneration Staging by Color Fundus Photography vs. Multimodal Imaging—Epidemiological Implications (The Coimbra Eye Study—Report 6)

      Age-Related Macular Degeneration Staging by Color Fundus Photography vs. Multimodal Imaging—Epidemiological Implications (The Coimbra Eye Study—Report 6)
      Epidemiology of age-related macular degeneration (AMD) is based on staging systems relying on color fundus photography (CFP). We aim to compare AMD staging using CFP to multimodal imaging with optical coherence tomography (OCT), infra-red (IR), and fundus autofluorescence (FAF), in a large cohort from the Epidemiologic AMD Coimbra Eye Study. All imaging exams from the participants of this population-based study were classified by a central reading center. CFP images were ...
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    7. Subthreshold Exudative Choroidal Neovascularization Associated With Age-Related Macular Degeneration Identified by Optical Coherence Tomography Angiography

      Subthreshold Exudative Choroidal Neovascularization Associated With Age-Related Macular Degeneration Identified by Optical Coherence Tomography Angiography
      Purpose: This article describes the clinical and multimodal imaging characteristics of subthreshold exudative choroidal neovascularization (CNV) associated with age-related macular degeneration (AMD). Methods: Among 3773 patients with AMD, 8 eyes (6 patients) were identified with the clinical phenotype of interest. Dilated fundus examinations, color fundus photography, fluorescein angiography (FA), indocyanine green angiography (ICGA), optical coherence tomography (OCT), and OCT angiography (OCTA) were performed. Results: OCT typically showed a moderately reflective ...
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    8. Optical Coherence Tomography-Angiography of a large retinal microaneurysm

      Optical Coherence Tomography-Angiography of a large retinal microaneurysm
      A 63-year-old healthy woman was referred for a retinal examination. Dilated fundus examination of the left eye revealed small retinal hemorrhage with surrounding exudation, most consistent with a large retinal microaneurysm, which was confirmed by fluorescein angiography and optical coherence tomography angiography (OCT-A). OCT-A has the potential to clearly delineate the anatomy of retinal aneurysms and could be used for diagnosis and surveillance, possibly replacing the current gold-standard fluorescein angiography.
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    9. Different Scan Protocols Affect the Detection Rates of Diabetic Retinopathy Lesions by Wide-field Swept-Source Optical Coherence Tomography Angiography

      Different Scan Protocols Affect the Detection Rates of Diabetic Retinopathy Lesions by Wide-field Swept-Source Optical Coherence Tomography Angiography
      Purpose To compare different scan protocols of wide field swept-source optical coherence tomography angiography (SS-OCTA) for the detection of diabetic retinopathy (DR) lesions. Design Comparison of diagnostic approaches. Methods A prospective, observational study was conducted at Mass Eye and Ear from December 2018 to July 2019. Proliferative diabetic retinopathy (PDR), non-proliferative diabetic retinopathy (NPDR) and diabetic patients without DR were included. All patients were imaged with a SS-OCTA using following ...
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    10. Effect of partial posterior vitreous detachment on spectral-domain optical coherence tomography retinal nerve fibre layer thickness measurements

      Effect of partial posterior vitreous detachment on spectral-domain optical coherence tomography retinal nerve fibre layer thickness measurements
      Background/aims To assess the effect of partial posterior vitreous detachment (pPVD) on spectral-domain optical coherence tomography (OCT) peripapillary retinal nerve fibre layer thickness (RNFL) measurements. Methods Spectral-domain OCT RNFL thickness measurements were obtained from 684 consecutive patients who were seen in the Massachusetts Eye and Ear Glaucoma Service. Of these patients, we compared RNFL thickness measurements between 101 eyes of 101 glaucoma suspects who met inclusion criteria (55 eyes ...
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    11. Artifact Rates for 2D Retinal Nerve Fiber Layer Thickness Versus 3D Retinal Nerve Fiber Layer Volume

      Artifact Rates for 2D Retinal Nerve Fiber Layer Thickness Versus 3D Retinal Nerve Fiber Layer Volume
      Purpose : To compare artifact rates in two-dimensional (2D) versus three-dimensional (3D) retinal nerve fiber layer (RNFL) scans using Spectralis optical coherence tomography (OCT) Methods : Thirteen artifact types in 2D and 3D RNFL scans were identified in 106 glaucomatous eyes and 95 normal eyes. Artifact rates were calculated per B-scan and per eye. In 3D volume scans, artifacts were counted only for the 97 B-scans used to calculate RNFL parameters for ...
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    12. MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emission

      MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emission
      ...Massachusetts Eye and Ear Infirmary Receives a 2020 NIH Grant for $491,220 for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emissions. The princi...
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    13. Imaging Artifacts and Segmentation Errors With Wide-Field Swept-Source Optical Coherence Tomography Angiography in Diabetic Retinopathy

      Imaging Artifacts and Segmentation Errors With Wide-Field Swept-Source Optical Coherence Tomography Angiography in Diabetic Retinopathy
      Purpose : To analyze imaging artifacts and segmentation errors with wide-field swept-source optical coherence tomography angiography (SS-OCTA) in diabetic retinopathy (DR). Methods : We conducted a prospective, observational study at Massachusetts Eye and Ear from December 2018 to March 2019. Proliferative diabetic retinopathy (PDR), nonproliferative diabetic retinopathy (NPDR), diabetic patients with no diabetic retinopathy (DR), and healthy control eyes were included. All patients were imaged with a SS-OCTA and the Montage Angio ...
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    14. Analysis of Neuroretinal Rim by Age, Race, and Sex Using High-Density 3-Dimensional Spectral-Domain Optical Coherence Tomography

      Analysis of Neuroretinal Rim by Age, Race, and Sex Using High-Density 3-Dimensional Spectral-Domain Optical Coherence Tomography
      rcis: Neuroretinal rim minimum distance band (MDB) thickness is significantly lower in older subjects and African Americans compared with whites. It is similar in both sexes. Purpose: To evaluate the relationship between age, race, and sex with the neuroretinal rim using high-density spectral-domain optical coherence tomography optic nerve volume scans of normal eyes. Methods: A total of 256 normal subjects underwent Spectralis spectral-domain optical coherence tomography optic nerve head volume ...
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  2. About Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary is a specialty hospital providing outstanding patient care for disorders of the eye, ear, nose, throat, head and neck. Founded in 1824, MEEI is an international leader in Ophthalmology and Otolaryngology research and a teaching partner of Harvard Medical School.