1. Massachusetts Eye and Ear Infirmary

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    1. Mentioned In 76 Articles

    2. Comprehensive Three-Dimensional Analysis of the Neuroretinal Rim in Glaucoma Using High-Density Spectral-Domain Optical Coherence Tomography Volume Scans

      Comprehensive Three-Dimensional Analysis of the Neuroretinal Rim in Glaucoma Using High-Density Spectral-Domain Optical Coherence Tomography Volume Scans
      Purpose : To describe spectral-domain optical coherence tomography (OCT) methods for quantifying neuroretinal rim tissue in glaucoma and to compare these methods to the traditional retinal nerve fiber layer thickness diagnostic parameter. Methods : Neuroretinal rim parameters derived from three-dimensional (3D) volume scans were compared with the two-dimensional (2D) Spectralis retinal nerve fiber layer (RNFL) thickness scans for diagnostic capability. This study analyzed one eye per patient of 104 glaucoma patients and ...
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    3. Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography

      Optimising keratoplasty for Peters' anomaly in infants using spectral-domain optical coherence tomography
      Purpose To present in vivo anterior segment optical coherence tomography (OCT) features of infants with Peters' anomaly obtained during presurgical examination under general anaesthesia, and to evaluate the impact of OCT features on surgical decision making. Methods This is a single-centre, consecutive, observational case series including 44 eyes of 27 infants with Peters' anomaly (518 months) undergoing keratoplasty. Medical records of patients were reviewed retrospectively. Clinical features and OCT findings ...
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    4. Patterns of Retinal Nerve Fiber Layer Loss in Different Subtypes of Open Angle Glaucoma Using Spectral Domain Optical Coherence Tomography

      Patterns of Retinal Nerve Fiber Layer Loss in Different Subtypes of Open Angle Glaucoma Using Spectral Domain Optical Coherence Tomography
      Purpose of the Study: The purpose of the study was to determine whether there are different patterns of retinal nerve fiber layer (RNFL) thinning as measured by spectral domain optical coherence tomography (SD-OCT) for 4 subtypes of open angle glaucoma (OAG): primary OAG (POAG), normal tension glaucoma (NTG), pseudoexfoliation glaucoma (PXG), and pigmentary glaucoma (PDG) and to compare them with normal controls. Materials and Methods: SD-OCT RNFL thickness values were ...
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    5. Free-Floating Pigmented Vitreous Cyst: Optical Coherence Tomography Findings

      Free-Floating Pigmented Vitreous Cyst: Optical Coherence Tomography Findings
      A 54-year-old woman presented with a chronic floater in the right eye. Dilated fundus examination revealed a pigmented free-floating vitreous cyst (Fig 1 A , Optos, Marlborough, MA). Saccades caused quick and fluid movements of the mobile sphere. Spectral-domain optical coherence tomography (SD OCT) (Fig 1 B , Spectralis; Heidelberg, Heidelberg, Germany) demonstrated a round, hyperreflective shell with hyporeflective contents. The lesion is anterior to the upper limit of the OCT and ...
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    6. Spectral-Domain Optical Coherence Tomography, Wide-Field Photography, and Fundus Autofluorescence Correlation of Posterior Ophthalmomyiasis Interna

      Spectral-Domain Optical Coherence Tomography, Wide-Field Photography, and Fundus Autofluorescence Correlation of Posterior Ophthalmomyiasis Interna
      Posterior ophthalmomyiasis interna is a rare, potentially devastating infestation of the posterior segment by fly larvae. The authors report the first demonstration of spectral-domain optical coherence tomography (SD-OCT) (Spectralis; Heidelberg Engineering, Heidelberg, Germany), wide-field angiography (Optos, Dunfermline, Scotland) and photography, and fundus autofluorescence with temporal progression during a period of 6 months. A 12-year-old white female presented with acute, painless vision loss with hand motions visual acuity. No larva was ...
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    7. Comparison of swept-source and enhanced depth imaging spectral-domain optical coherence tomography in quantitative characterisation of the optic nerve head

      Comparison of swept-source and enhanced depth imaging spectral-domain optical coherence tomography in quantitative characterisation of the optic nerve head
      Aims To compare swept-source optical coherence tomography (SS-OCT) and enhanced depth imaging spectral-domain OCT (EDI-OCT) in quantitative assessment of optic nerve head (ONH) parameters. Methods In a cross-sectional study, patients with primary open angle glaucoma (POAG) and age-matched control subjects underwent SS-OCT and EDI-OCT B-scans of the ONH in a single visit. Two masked readers independently measured the horizontal and vertical lamina cribrosa depth (LCDH and LCDV, respectively), as well ...
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    8. Postdoctoral research position for Biomedical/Optics Engineer Scientist at Harvard Medical School and Wellman Center

      Postdoctoral research position for Biomedical/Optics Engineer Scientist at Harvard Medical School and Wellman Center
      The ear is a remarkable example of a biomechanical system. The goal of the OtoBiomechanics Group in the Otolaryngology Department at the Harvard Medical School is to use the OCT imaging modality combined with computational models and physiological measurements to understand the high sensitivity, high frequency selectivity and wide bandwidth of mammalian hearing. The project is well funded by grants from the NIH. Applications are invited for a post-doctoral research ...
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    9. Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure–function map for OCT

      Correlation of localized glaucomatous visual field defects and spectral domain optical coherence tomography retinal nerve fiber layer thinning using a modified structure–function map for OCT
      Purpose To study the correlation between glaucomatous visual field (VF) defects assessed by standard automated perimetry (SAP) and peripapillary retinal nerve fiber layer (RNFL) thinning measured by spectral domain optical coherence tomography (OCT) using a modified OCT-based peripapillary RNFL structurefunction map. Patients and methods Perimetric glaucoma patients and age-matched normal control subjects were recruited from a university hospital clinic. All eyes underwent testing with the Spectralis spectral domain OCT and ...
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    10. Carmen A. Puliafito, MD, MBA, Former Dean of Keck School of Medicine of the University of Southern California, Joins Ophthotech as Chief of Strategic Development

      Carmen A. Puliafito, MD, MBA, Former Dean of Keck School of Medicine of the University of Southern California, Joins Ophthotech as Chief of Strategic Development
      ...completed his residency and fellowships in ophthalmic pathology and vitreoretinal diseases and surgery at the Massachusetts Eye and Ear Infirmary. Dr. Puliafito is on leave from his position as Professor of Ophthalmology...
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    11. OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS OF MACULAR EDEMA AND HARD EXUDATES AND THEIR ASSOCIATION WITH LIPID SERUM LEVELS IN TYPE 2 DIABETES

      OPTICAL COHERENCE TOMOGRAPHY CHARACTERISTICS OF MACULAR EDEMA AND HARD EXUDATES AND THEIR ASSOCIATION WITH LIPID SERUM LEVELS IN TYPE 2 DIABETES
      Purpose: To determine whether hyperreflective foci (HF) and macular thickness on spectral domain ocular coherence tomography are associated with lipid levels in patients with Type 2 diabetes. Methods: Two hundred and thirty-eight participants from four sites had fundus photographs and spectral domain ocular coherence tomography images graded for hard exudates and HF, respectively. Regression models were used to determine the association between serum lipid levels and 1) presence of HF ...
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    12. Investigation of middle ear anatomy and function with combined video otoscopy-phase sensitive OCT

      Investigation of middle ear anatomy and function with combined video otoscopy-phase sensitive OCT
      We report the development of a novel otoscopy probe for assessing middle ear anatomy and function. Video imaging and phase-sensitive optical coherence tomography are combined within the same optical path. A sound stimuli channel is incorporated as well to study middle ear function. Thus, besides visualizing the morphology of the middle ear, the vibration amplitude and frequency of the eardrum and ossicles are retrieved as well. Preliminary testing on cadaveric ...
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    13. Intraoperative imaging of pediatric vocal fold lesions using optical coherence tomography

      Intraoperative imaging of pediatric vocal fold lesions using optical coherence tomography
      Optical coherence tomography (OCT) has been previously identified as a promising tool for exploring laryngeal pathologies in adults. Here, we present an OCT handheld probe dedicated to imaging the unique geometry involved in pediatric laryngoscopy. A vertical cavity surface emitting laser-based wavelength-swept OCT system operating at 60 frames per second was coupled to the probe to acquire three-dimensional (3-D) volumes in vivo . In order to evaluate the performance of the ...
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    14. Pioneering Glaucoma Expert Appointed Chair of the Department of Ophthalmology at NYU Langone Medical Center

      Pioneering Glaucoma Expert Appointed Chair of the Department of Ophthalmology at NYU Langone Medical Center
      ...nd research fellowships in glaucoma at the Howe Laboratory of Ophthalmology, part of Harvard Medical School's Massachusetts Eye and Ear Infirmary. Dr. Schuman and colleagues were honored in 2012 with the Champalimaud Vi...
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    15. Using attenuation coefficients from optical coherence tomography as markers of vocal fold maturation

      Using attenuation coefficients from optical coherence tomography as markers of vocal fold maturation
      Objectives/Hypothesis Optical coherence tomography (OCT) is a promising technology to noninvasively assess vocal fold microanatomy. The goal of this study was to develop a methodology using OCT to identify quantifiable markers of vocal fold development. Study Design In vivo study. Methods A two-step process was developed to reproducibly image the midmembranous vocal fold edge of 10 patients younger than 2 years and 10 patients between 11 and 16 years ...
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    16. 1-15 of 76 1 2 3 4 5 »
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  2. About Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary is a specialty hospital providing outstanding patient care for disorders of the eye, ear, nose, throat, head and neck. Founded in 1824, MEEI is an international leader in Ophthalmology and Otolaryngology research and a teaching partner of Harvard Medical School.