1. Massachusetts Eye and Ear Infirmary

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    1. Mentioned In 169 Articles

    2. Cochlear motion across the reticular lamina implies that it is not a stiff plate

      Explore Nature Publishing Group Otolaryngology
      Cochlear motion across the reticular lamina implies that it is not a stiff plate
      Within the cochlea, the basilar membrane (BM) is coupled to the reticular lamina (RL) through three rows of piezo-like outer hair cells (OHCs) and supporting cells that endow mammals with sensitive hearing. Anatomical differences across OHC rows suggest differences in their motion. Using optical coherence tomography, we measured in vivo and postmortem displacements through the gerbil round-window membrane from approximately the 4047 kHz best-frequency (BF) regions. Our high spatial resolution ...
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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    3. Characterising collateral vessels in eyes with branch retinal vein occlusions using widefield swept-source optical coherence tomography angiography

      Explore BJO Online Ophthalmology
      Characterising collateral vessels in eyes with branch retinal vein occlusions using widefield swept-source optical coherence tomography angiography
      Background/aims: To characterise the morphology, location and functional significance of both macular and extramacular collateral vessels (CVs) in patients with a history of branch retinal vein occlusion (BRVO) using widefield swept-source optical coherence tomography angiography (WF SS OCTA). Methods: Patients with a history of BRVO underwent WF SS OCTA testing to acquire 1212 mm images, which were evaluated for CVs and non-perfusion area (NPA). Region of interest analysis of ...
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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    4. Combined Model of OCT Angiography and Structural OCT Parameters to Predict Paracentral Visual Field Loss in Primary Open-Angle Glaucoma

      Explore ScienceDirect Ophthalmology
      Combined Model of OCT Angiography and Structural OCT Parameters to Predict Paracentral Visual Field Loss in Primary Open-Angle Glaucoma
      Purpose: To assess a model combining optical coherence tomography angiography (OCTA) and optical coherence tomography (OCT) parameters to predict the severity of paracentral visual field (VF) loss in primary open-angle glaucoma (POAG). Design: Cross-sectional study. Participants: Forty-four patients with POAG and 42 control subjects underwent OCTA and OCT imaging with a swept-source OCT device. Methods: The circumpapillary microvasculature was quantified for vessel density (cpVD) and flow (cpFlow) after delineation of ...
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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    5. Comparison of hyperreflective foci in macular edema secondary to multiple etiologies with spectral-domain optical coherence tomography: An observational study

      Explore BMC Ophthalmology Ophthalmology
      Comparison of hyperreflective foci in macular edema secondary to multiple etiologies with spectral-domain optical coherence tomography: An observational study
      Background: Hyperreflective foci (HRF) features in macular edema associated with different etiologies may indicate the disease pathogenesis and help to choose proper treatment. The goal of this study is to investigate the retinal microstructural features of macular edema (ME) secondary to multiple etiologies with spectral-domain optical coherence tomography (SD-OCT) and analyze the origin of HRF in ME. Methods: This was a retrospective study. SD-OCT images were reviewed to investigate macular ...
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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary Peking University

    6. Widefield Swept-Source Optical Coherence Tomography Angiography Findings in Wagner Syndrome

      Explore LWW Online Ophthalmology
      Widefield Swept-Source Optical Coherence Tomography Angiography Findings in Wagner Syndrome
      Purpose: To describe novel clinical and angiographic findings in Wagner syndrome. Methods: A retrospective case series of three related patients with Wagner syndrome. Patients underwent standard OCT, B-scan ultrasonography, and fluorescein angiography in addition to wide field swept-source OCT angiography (WF SS-OCTA) (PLEX Elite 9000, Carl Zeiss Meditec Inc.). Patients underwent genetic testing for a panel of hereditary vitreoretinopathies. Results: Three related patients with Wagner syndrome were identified. All were ...
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      Mentions: Harvard University Carl Zeiss Meditec Massachusetts Eye and Ear Infirmary

    7. Imaging-based Assessment of Choriocapillaris: A Comprehensive Review

      Explore Taylor & Francis Online Ophthalmology
      Imaging-based Assessment of Choriocapillaris: A Comprehensive Review
      PURPOSE Over the past two decades, advancements in imaging modalities have significantly evolved the diagnosis and management of retinal diseases. Through these novel platforms, we have developed a deeper understanding of the anatomy of the choroidal vasculature and the choriocapillaris. The recently developed tools such as optical coherence tomography (OCT) and OCT angiography (OCTA) have helped elucidate the pathological mechanisms of several posterior segment diseases. In this review, we have ...
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      Mentions: University of Michigan Harvard University Massachusetts Eye and Ear Infirmary

    8. Reproducibility of Neuroretinal Rim Measurements Obtained from High-Density Spectral Domain Optical Coherence Tomography Volume Scans

      Explore Medical Journals Publisher Ophthalmology
      Reproducibility of Neuroretinal Rim Measurements Obtained from High-Density Spectral Domain Optical Coherence Tomography Volume Scans
      Purpose: To compare the reproducibility of two-dimensional (2D) peripapillary retinal nerve fiber layer (RNFL) thickness and three-dimensional (3D) neuroretinal rim measurements using spectral domain optical coherence tomography (SDOCT) in normal and glaucoma subjects. Methods: One eye per subject for 27 normal and 40 glaucoma subjects underwent repeat SDOCT RNFL thickness scans and optic nerve volume scans on the same day. From the volume scan, custom software calculated five neuroretinal rim ...
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      Mentions: University of Florida Columbia University Harvard University

    9. Retinal microvasculature and vasoreactivity changes in hypertension using optical coherence tomography-angiography

      Explore Home - Springer Ophthalmology
      Retinal microvasculature and vasoreactivity changes in hypertension using optical coherence tomography-angiography
      Purpose: To evaluate the retinal vasculature and vasoreactivity of patients with hypertension (HTN) using spectral domain optical coherence tomography angiography (SD-OCTA). Methods: Patients with and without a diagnosis of HTN were included in this cross-sectional observational study. All eyes were imaged with SD-OCTA using 3 mm 3 mm and 6 mm 6 mm centered on both the fovea and optic disk. A second 6 mm 6 mm scan was taken ...
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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    10. Nonperfusion Area and Other Vascular Metrics by Wider Field Swept-Source OCT Angiography as Biomarkers of Diabetic Retinopathy Severity

      Explore Home Page Ophthalmology
      Nonperfusion Area and Other Vascular Metrics by Wider Field Swept-Source OCT Angiography as Biomarkers of Diabetic Retinopathy Severity
      Purpose: To study the wider field swept-source optical coherence tomography angiography (WF SS-OCTA) metrics, especially non-perfusion area (NPA), in the diagnosing and staging of DR. Design: Cross-sectional observational study (November 2018-September 2020). Participants: 473 eyes of 286 patients (69 eyes of 49 control patients and 404 eyes of 237 diabetic patients). Methods: We imaged using 6mm6mm and 12mm12mm angiograms on WF SS-OCTA. Images were analyzed using the ARI Network and ...
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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    11. MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emissions

      Explore Optical Coherence Tomography News Otolaryngology , Funding
      MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emissions
      ...t can be validated using non-invasive hearing-threshold and OAE measurements.

      Massachusetts Eye and Ear Infirmary Received a 2022 NIH Grant for $117,133 for Measuring and Modeling the Coch...

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      Mentions: National Institutes of Health Massachusetts Eye and Ear Infirmary

    12. Juxtapapillary Choroidal Neovascular Membrane as a Complication of Optic Disc Drusen: Multimodal Imaging With Swept Source-Optical Coherence Tomography and Optical Coherence Tomography Angiography

      Explore LWW Online Neurology , Ophthalmology
      Juxtapapillary Choroidal Neovascular Membrane as a Complication of Optic Disc Drusen: Multimodal Imaging With Swept Source-Optical Coherence Tomography and Optical Coherence Tomography Angiography
      A 55-year-old Caucasian man presented to the neuro-ophthalmology department for follow-up evaluation due to long-standing bilateral optic nerve head drusen (ONHD). On examination, the BCVA was 20/20-2 in both eyes. Dilated fundus examination revealed extensive ONHD in both eyes, retinal hemorrhages, exudates inferonasal to the macula, and macular edema inferotemporal to the disc margin. Automated visual field testing revealed generalized depression in both eyes. Late phase leakage was observed ...
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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    13. Cochlear Fluid Spaces and Structures of the Gerbil High-Frequency Region Measured Using Optical Coherence Tomography (OCT)

      Explore Home - Springer Otolaryngology
      Cochlear Fluid Spaces and Structures of the Gerbil High-Frequency Region Measured Using Optical Coherence Tomography (OCT)
      Since it has been difficult to directly observe the morphology of the living cochlea, our ability to infer the mechanical functioning of the living ear has been limited. Nearly all our knowledge about cochlear morphology comes from postmortem tissue that was fixed and processed using procedures that possibly distort the structures and fluid spaces of the organ of Corti. In this study, optical coherence tomography was employed to obtain volumetric ...
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      Mentions: Harvard University Massachusetts Eye and Ear Infirmary

    16. MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emission

      Explore Optical Coherence Tomography News Otolaryngology , Funding
      MEEI Receives NIH Grant for Measuring and Modeling the Cochlear Motions that Drive the Inner and Outer Hair Cells and Produce Otoacoustic Emission
      ...t can be validated using non-invasive hearing-threshold and OAE measurements.

      Massachusetts Eye and Ear Infirmary Received a 2022 NIH Grant for $488,619 for Measuring and Modeling the Coch...

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      Mentions: National Institutes of Health Harvard University Massachusetts Eye and Ear Infirmary
    17. 1-15 of 169 1 2 3 4 ... 10 11 12 »
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  4. About Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary

    Massachusetts Eye and Ear Infirmary is a specialty hospital providing outstanding patient care for disorders of the eye, ear, nose, throat, head and neck. Founded in 1824, MEEI is an international leader in Ophthalmology and Otolaryngology research and a teaching partner of Harvard Medical School.

  5. Related Topics

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    3. Spectral domain optical coherence tomography for quantitative evaluation of drusen and associated structural changes in non-neovascular age-related macular degeneration
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