1. Masataka Nakano

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    1-13 of 13
    1. Mentioned In 13 Articles

    2. Are Microcalcification and Hemosiderin Really Limitations of OCT in Detection of TCFA?

      Are Microcalcification and Hemosiderin Really Limitations of OCT in Detection of TCFA?
      With great interest, we read the recent work by Fujii et al. (1) published in iJACC reporting the diagnostic accuracy of optical coherence tomography (OCT) and grayscale intravascular ultrasound for the detection of coronary thin cap fibroatheroma (TCFA) with histologic validation in human autopsy hearts. In this publication, Fujii et al. (1) documented a limited capability of OCT and intravascular ultrasound for TCFA identification when each imaging device was solely ...
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    3. Evaluation of Coronary Arterial Calcification - Ex-vivo Assessment by Optical Frequency Domain Imaging

      Evaluation of Coronary Arterial Calcification - Ex-vivo Assessment by Optical Frequency Domain Imaging
      Aims The purpose of this study was to determine the diagnostic ability of optical frequency domain imaging (OFDI) to carry out quantitative and qualitative evaluation of coronary calcification in comparing with ex vivo human autopsy heart specimens. Methods Analysis was carried out in 25 coronary artery specimen obtained from 16 cadavers that were imaged ex-vivo imaging by OFDI and intravascular ultrasound (IVUS). Of 235 cross-sections obtained for histologic evaluation, 149 ...
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    4. Histogram Analysis of Lipid-Core Plaques in Coronary Computed Tomographic Angiography: Ex Vivo Validation Against Histology

      Histogram Analysis of Lipid-Core Plaques in Coronary Computed Tomographic Angiography: Ex Vivo Validation Against Histology
      Purpose: In coronary computed tomographic angiography (CTA), low attenuation of coronary atherosclerotic plaque is associated with lipid-rich plaques. However, an overlap in Hounsfield units (HU) between fibrous and lipid-rich plaque as well as an influence of luminal enhancement on plaque attenuation was observed and may limit accurate detection of lipid-rich plaques by CTA. We sought to determine whether the quantitative histogram analysis improves accuracy of the detection of lipid-core plaque ...
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    5. Update on acute coronary syndromes: the pathologists' view

      Update on acute coronary syndromes: the pathologists' view
      Although mortality rates from coronary heart disease in the western countries have declined in the last few decades, morbidity caused by this disease is increasing and a substantial number of patients still suffer acute coronary syndrome (ACS) and sudden cardiac death. Acute coronary syndrome occurs as a result of myocardial ischaemia and its manifestations include acute myocardial infarction and unstable angina. Culprit plaque morphology in these patients varies from thrombosis ...
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    6. Differentiation of Early from Advanced Coronary Atherosclerotic Lesions: Systematic Comparison of CT, Intravascular US, and Optical Frequency Domain Imaging with Histopathologic Examination in ex Vivo Human Heart

      Differentiation of Early from Advanced Coronary Atherosclerotic Lesions: Systematic Comparison of CT, Intravascular US, and Optical Frequency Domain Imaging with Histopathologic Examination in ex Vivo Human Heart
      Purpose: To establish an ex vivo experimental setup for imaging coronary atherosclerosis with coronary computed tomographic (CT) angiography, intravascular ultrasonography (US), and optical frequency domain imaging (OFDI) and to investigate their ability to help differentiate early from advanced coronary plaques. Materials and Methods: All procedures were performed in accordance with local and federal regulations and the Declaration of Helsinki. Approval of the local Ethics Committee was obtained. Overall, 379 histologic ...
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    7. Microvascular Obstruction Is Caused by Atherothrombosis in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention

      Microvascular Obstruction Is Caused by Atherothrombosis in Patients With Acute Coronary Syndrome Undergoing Percutaneous Coronary Intervention
      The diagnosis of acute coronary syndrome (ACS) is primarily based on the mode of clinical presentation and is a term used for any conditions suggesting the acute induction of myocardial ischemia. The precise molecular and cellular triggers that lead to ACS remain poorly understood; however, histopathologic studies have illustrated several mechanisms that may explain the sudden onset of symptoms in ACS patients. The most common substrate underlying ACS is thought ...
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    8. High Levels of Systemic Myeloperoxidase Are Associated With Coronary Plaque Erosion in Patients With Acute Coronary Syndromes: A Clinicopathological Study

      High Levels of Systemic Myeloperoxidase Are Associated With Coronary Plaque Erosion in Patients With Acute Coronary Syndromes: A Clinicopathological Study
      ...tory biomarkers reflect specific acute complications of coronary atherosclerosis. Giuseppe Ferrante, MD, PhD; Masataka Nakano, MD; Francesco Prati, MD; Giampaolo Niccoli, MD, PhD; Maria T. Mallus, MD, PhD; Vito Ramazzott...
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    9. 1-13 of 13
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  2. About Masataka Nakano

    Masataka Nakano is at the CVPath Institute Inc.