1. Masahiro Akiba

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    1. Mentioned In 33 Articles

    2. Fundus analysis apparatus and fundus observation apparatus

      Fundus analysis apparatus and fundus observation apparatus
      A fundus analysis apparatus includes a storage, an area setting unit, and a morphological information generating unit. The storage is configured to store OCT information acquired by applying optical coherence tomography to the fundus of an eye. The area setting unit is configured to set a front area corresponding to a front surface of the lamina cribrosa and a rear area corresponding to a rear surface of the lamina cribrosa ...
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    3. Assessment of the deformation of the outer nuclear layer in the Epiretinal membrane using spectral-domain optical coherence tomography

      Assessment of the deformation of the outer nuclear layer in the Epiretinal membrane using spectral-domain optical coherence tomography
      Background: We aimed to investigate the deformation of the outer nuclear layer using optical coherence tomography in patients with epiretinal membrane (ERM) and its relationship with metamorphopsia. Methods: Thirty-nine eyes from 39 patients with ERM were included in the study. Patients with the subtypes of pseudo macula hole and lamellar hole were excluded. Twenty-one fellow eyes without macular disease were included as normal controls. Forty-nine B-scan images were obtained in ...
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      Mentions: Masahiro Akiba
    4. Retinal Arteriole Pulse Waveform Analysis Using a Fully-Automated Doppler Optical Coherence Tomography Flowmeter: a Pilot Study

      Retinal Arteriole Pulse Waveform Analysis Using a Fully-Automated Doppler Optical Coherence Tomography Flowmeter: a Pilot Study
      Purpose : To evaluate the repeatability and reproducibility of the measurement of retinal arteriole pulse waveforms using a novel fully-automated Doppler optical coherence tomography (DOCT) flowmeter in healthy subjects. Methods : Twenty eyes of 20 healthy subjects were included to test the intrasession repeatability of pulse waveform analysis. DOCT measurements were performed based on a newly developed instantaneous Doppler angle measurement method. Upstroke time (UT), which is the time from the minimum ...
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    5. Glaucoma Diagnosis with Machine Learning Based on Optical Coherence Tomography and Color Fundus Image

      Glaucoma Diagnosis with Machine Learning Based on Optical Coherence Tomography and Color Fundus Image
      This study aimed to develop a machine learning-based algorithm for glaucoma diagnosis in patients with open-angle glaucoma, based on three-dimensional optical coherence tomography (OCT) data and color fundus images. In this study, 208 glaucomatous and 149 healthy eyes were enrolled, and color fundus images and volumetric OCT data from the optic disc and macular area of these eyes were captured with a spectral-domain OCT (3D OCT-2000, Topcon). Thickness and deviation ...
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    6. Reducing speckle noise in optical coherence tomography images

      Reducing speckle noise in optical coherence tomography images
      A method and system are proposed to obtain a reduced speckle noise image of a subject from optical coherence tomography (OCT) image data of the subject. The cross sectional images each comprise a plurality of scan lines obtained by measuring the time delay of light reflected, in a depth direction, from optical interfaces within the subject. The method comprises two aligning steps. First the cross sectional images are aligned, then ...
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    7. Pilot study for three-dimensional assessment of laminar pore structure in patients with glaucoma, as measured with swept source optical coherence tomography

      Pilot study for three-dimensional assessment of laminar pore structure in patients with glaucoma, as measured with swept source optical coherence tomography
      Purpose To develop a method to quantify, based on swept-source optical coherence tomography (OCT), the 3D structure of the laminar pores in patients with glaucoma. Methods This retrospective study examined 160 laminar pores from 8 eyes of 8 cases: 4 normal subjects and 4 open-angle glaucoma (OAG) patients. We reconstructed 3D volume data for a 3 x 3 mm disc, using a method similar to OCT angiography, and segmented the ...
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      Mentions: Masahiro Akiba
    8. Retinal blood flow reduction after panretinal photocoagulation in Type 2 diabetes mellitus: Doppler optical coherence tomography flowmeter pilot study

      Retinal blood flow reduction after panretinal photocoagulation in Type 2 diabetes mellitus: Doppler optical coherence tomography flowmeter pilot study
      .... The specific roles of the author is articulated in the ‘author contributions’ section. Competing interests: Masahiro Akiba is employee of Topcon Corporation, Japan. (E) This does not alter our adherence to PLOS ONE pol...
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    9. IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      IMPROVED DETECTION AND DIAGNOSIS OF POLYPOIDAL CHOROIDAL VASCULOPATHY USING A COMBINATION OF OPTICAL COHERENCE TOMOGRAPHY AND OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To assess the ability of optical coherence tomography (OCT) alone and in combination with OCT angiography (OCTA) to differentiate polypoidal choroidal vasculopathy (PCV) from neovascular age-related macular degeneration , as compared to fluorescein angiography and indocyanine green angiography. Methods: This is a cross-sectional study. All participants had a standardized history, clinical examination including measurement of best-corrected visual acuity, slit-lamp biomicroscopy, and indirect fundus examination, and underwent standardized imaging (color photography ...
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    10. Classification of optic disc shape in glaucoma using machine learning based on quantified ocular parameters

      Classification of optic disc shape in glaucoma using machine learning based on quantified ocular parameters
      Purpose This study aimed to develop a machine learning-based algorithm for objective classification of the optic disc in patients with open-angle glaucoma (OAG), using quantitative parameters obtained from ophthalmic examination instruments. Methods This study enrolled 163 eyes of 105 OAG patients (age: 62.3 12.6, mean deviation of Humphrey field analyzer: -8.9 7.5 dB). The eyes were classified into Nicolelas 4 optic disc types by 3 glaucoma ...
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    11. Repeatability and Reproducibility of Retinal Blood Flow Measurement Using a Doppler Optical Coherence Tomography Flowmeter in Healthy Subjects

      Repeatability and Reproducibility of Retinal Blood Flow Measurement Using a Doppler Optical Coherence Tomography Flowmeter in Healthy Subjects
      Purpose : To evaluate the repeatability and reproducibility of retinal blood flow (RBF) measurements in humans by using new auto-alignment and measurement software in a commercially available Doppler optical coherence tomography (DOCT) system. Methods : The DOCT flowmeter assessed the intrasession repeatability and the intersession and interobserver reproducibility of the RBF measurements. For intrasession repeatability, the coefficients of variation (CVs) of five repeated RBF measurements were calculated at the retinal arteries and ...
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    12. Speckle Reduction in 3D Optical Coherence Tomography of Retina by A-Scan Reconstruction

      Speckle Reduction in 3D Optical Coherence Tomography of Retina by A-Scan Reconstruction
      Optical coherence tomography (OCT) is a micrometer-scale, cross-sectional imaging modality for biological tissue. It has been widely used for retinal imaging in ophthalmology. Speckle noise is problematic in OCT. A raw OCT image/volume usually has very poor image quality due to speckle noise, which often obscures the retinal structures. Overlapping scan is often used for speckle reduction in a 2D line-scan. However, it leads to an increase of the ...
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    13. Clinical Factors Associated with Lamina Cribrosa Thickness in Patients with Glaucoma, as Measured with Swept Source Optical Coherence Tomography

      Clinical Factors Associated with Lamina Cribrosa Thickness in Patients with Glaucoma, as Measured with Swept Source Optical Coherence Tomography
      Purpose To investigate the influence of various risk factors on thinning of the lamina cribrosa (LC), as measured with swept-source optical coherence tomography (SS-OCT; Topcon). Methods This retrospective study comprised 150 eyes of 150 patients: 22 normal subjects, 28 preperimetric glaucoma (PPG) patients, and 100 open-angle glaucoma patients. Average LC thickness was determined in a 3 x 3 mm cube scan of the optic disc, over which a 4 x ...
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    14. Analysis of Peripapillary Geometric Characters in High Myopia Using Swept-Source Optical Coherence Tomography

      Analysis of Peripapillary Geometric Characters in High Myopia Using Swept-Source Optical Coherence Tomography
      Purpose : We measured the three-dimensional geometric profile around the optic nerve head (ONH) using swept-source optical coherence tomography (SS-OCT) in highly myopic eyes. Methods : We studied 114 highly myopic eyes (6.0 diopters [D]) of 114 patients without glaucoma. Eyes were examined using the prototype SS-OCT. The retinal pigment epithelium (RPE) and chorioscleral interface were traced, and the mean y -axis coordinates of 24 sectors were calculated in circular peripapillary ...
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    15. 3D Evaluation of the Lamina Cribrosa with Swept-Source Optical Coherence Tomography in Normal Tension Glaucoma

      3D Evaluation of the Lamina Cribrosa with Swept-Source Optical Coherence Tomography in Normal Tension Glaucoma
      Purpose Although the lamina cribrosa (LC) is the primary site of axonal damage in glaucoma, adequate methods to image and measure it are currently lacking. Here, we describe a noninvasive, in vivo method of evaluating the LC, based on swept-source optical coherence tomography (SS-OCT), and determine this methods ability to quantify LC thickness. Methods This study comprised 54 eyes, including normal (n = 18), preperimetric glaucoma (PPG; n = 18), and normal ...
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    16. Analysis of Retinal Nonperfusion Using Depth-Integrated Optical Coherence Tomography Images in Eyes with Branch Retinal Vein Occlusion

      Analysis of Retinal Nonperfusion Using Depth-Integrated Optical Coherence Tomography Images in Eyes with Branch Retinal Vein Occlusion
      PURPOSE: To assess the morphology of areas of complete retinal nonperfusion in eyes with branch retinal vein occlusion (BRVO) by enface images of optical coherence tomography (OCT). METHODS: Forty-six eyes with BRVO which underwent swept-source OCT (SS-OCT) and fluorescein angiography were enrolled. Depth-integrated images of the neural retina delineated by automated segmentation algorithm were obtained using SS-OCT. The findings in a 6 x 6-mm area on enface SS-OCT scans at ...
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  2. About Masahiro Akiba

    Masahiro Akiba is a Researcher at the Yamagata Promotional Organization for Industrial Technology, 2-2-1, Matsuei, Yamagata 990-2473, Japan.