1. Marinko V. Sarunic

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    1. Mentioned In 71 Articles

    2. Fourier Domain Optical Coherence Tomography as a Noninvasive Means for In Vivo Detection of Retinal Degeneration in Xenopus laevis Tadpoles

      ...ve Means for In Vivo Detection of Retinal Degeneration in Xenopus laevis Tadpoles Damian C. Lee,^1 Jing Xu,^2 Marinko V. Sarunic,^2 and Orson L. Moritz^1 ^From the ^1Department of Ophthalmology and Visual Sciences, Unive...
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    3. Methods, systems and computer program products for characterizing structures based on interferometric phase data

      Methods, systems and computer program products for characterizing structures based on interferometric phase data
      Structure profiles from optical interferometric data can be identified by obtaining a plurality of broadband interferometric optical profiles of a structure as a function of structure depth in an axial direction. Each of the plurality of interferometric optical profiles include a reference signal propagated through a reference path and a sample signal reflected from a sample reflector in the axial direction. An axial position corresponding to at least a portion ...
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    4. Intra-retinal Layer Segmentation in Optical Coherence Tomography Using an Active Contour Approach

      Optical coherence tomography (OCT) is a non-invasive, depth resolved imaging modality that has become a prominent ophthalmic diagnostic technique. We present an automatic segmentation algorithm to detect intra-retinal layers in OCT images acquired from rodent models of retinal degeneration. We adapt Chan–Vese’s energy-minimizing active contours without edges for OCT images, which suffer from low contrast and are highly corrupted by noise. We adopt a multi-phase framework with a ...
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    5. Fourier domain optical coherence tomography (FD-OCT) as a non-invasive means for in vivo detection of retinal degeneration in Xenopus laevis tadpoles.

      Purpose: To determine the efficacy of Fourier domain-optical coherence tomography (FD-OCT) as a non-invasive and non-sacrificial method for detecting in vivo, pathological signs of retinal degeneration in Xenopus laevis larvae. Methods: A prototype OCT system using Fourier domain detection customized for tadpole imaging was used to non-invasively obtain retinal scans in two different transgenic X. laevis models of retinal degeneration. FD-OCT retinal scans were compared with laser scanning confocal micrographs ...
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    6. In vivo imaging of the Mouse Model of X-Linked Juvenile Retinoschisis Using Fourier Domain Optical Coherence Tomography

      Purpose: The purpose of this study is to investigate Fourier Domain Optical Coherence Tomography (FD OCT) as a non-invasive tool for retinal imaging in the Rs1h knockout mouse (model for X-linked Juvenile Retinoschisis). Methods: A prototype spectrometer based FD OCT system was used in combination with a custom optical beam-scanning platform. Images of the retinas from wild type and Rs1h knockout mice were acquired non-invasively using FD OCT with the ...
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    7. Detailed Visualization of the Anterior Segment Using Fourier-Domain Optical Coherence Tomography

      Objective To study details of the anterior chamber drainage angle using Fourier-domain optical coherence tomography in healthy subjects and patients with angle abnormalities. Methods A high-speed anterior segment optical coherence tomography prototype was developed using a 1310-nm-wavelength swept light source. Six healthy subjects and 6 patients with glaucoma were imaged in an observational cross-sectional study. Results Schlemm’s canal and the trabecular meshwork were visualized in all of the patients ...
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    8. Detailed Visualization of the Anterior Segment Using Fourier-Domain Optical Coherence Tomography

      Objective  To study details of the anterior chamber drainage angle using Fourier-domain optical coherence tomography in healthy subjects and patients with angle abnormalities. Methods  A high-speed anterior segment optical coherence tomography prototype was developed using a 1310-nm-wavelength swept light source. Six healthy subjects and 6 patients with glaucoma were imaged in an observational cross-sectional study. Results  Schlemm’s canal and the trabecular meshwork were visualized in all of the patients ...
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    9. Spectrometer based Fourier domain optical coherence tomography of the mouse retina

      We present a custom Fourier Domain Optical Coherence Tomography (FDOCT) system adapted to imaging the retinal structures in mice. The FDOCT system utilized spectrometer detection, and operated at a central wavelength of 826nm with a FWHM spectral bandwidth of 72nm, corresponding to an axial resoluti ... [Proc. SPIE Int. Soc. Opt. Eng. 6847, 684731 (2008)] published Mon Feb 18, 2008.
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  2. About Marinko V. Sarunic

    Marinko V. Sarunic

    Marinko V. Sarunic is an Associate Professor, School of Engineering Science, Simon Fraser University, Vancouver, Canada. Dr. Marinko Sarunic is an SFU alumnus, having received a B.A.Sc. in Engineering Physics from Simon Fraser University in 1998. He continued on at SFU for a M.A.Sc. thesis, under the supervision of Dr. Glenn Chapman. In 2006, he completed a PhD at Duke University with a research focus on Fourier domain optical coherence tomography.