1. Marina Marjanovic

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    1. Mentioned In 15 Articles

    2. Investigating the healing mechanisms of an angiogenesis-promoting topical treatment for diabetic wounds using multimodal microscopy

      Investigating the healing mechanisms of an angiogenesis-promoting topical treatment for diabetic wounds using multimodal microscopy
      Impaired skin wound healing is a significant co-morbid condition of diabetes that is caused by poor microcirculation, among other factors. Studies have shown that angiogenesis, a critical step in the wound healing process in diabetic wounds, can be promoted under hypoxia. In this study, an angiogenesis-promoting topical treatment for diabetic wounds, which promotes angiogenesis by mimicking a hypoxic environment via inhibition of prolyl hydroxylase resulting in elevation or maintenance of ...
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    3. Intraoperative optical coherence tomography for soft tissue sarcoma differentiation and margin identification

      Intraoperative optical coherence tomography for soft tissue sarcoma differentiation and margin identification
      Background and Objective Sarcomas are rare but highly aggressive tumors, and local recurrence after surgical excision can occur in up to 50% cases. Therefore, there is a strong clinical need for accurate tissue differentiation and margin assessment to reduce incomplete resection and local recurrence. The purpose of this study was to investigate the use of optical coherence tomography (OCT) and a novel image texture-based processing algorithm to differentiate sarcoma from ...
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    4. Intraoperative optical coherence tomography for assessing human lymph nodes for metastatic cancer

      Intraoperative optical coherence tomography for assessing human lymph nodes for metastatic cancer
      Background Evaluation of lymph node (LN) status is an important factor for detecting metastasis and thereby staging breast cancer. Currently utilized clinical techniques involve the surgical disruption and resection of lymphatic structure, whether nodes or axillary contents, for histological examination. While reasonably effective at detection of macrometastasis , the majority of the resected lymph nodes are histologically negative. Improvements need to be made to better detect micrometastasis , minimize or eliminate lymphatic ...
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    5. Real-time Imaging of the Resection Bed Using a Handheld Probe to Reduce Incidence of Microscopic Positive Margins in Cancer Surgery

      Real-time Imaging of the Resection Bed Using a Handheld Probe to Reduce Incidence of Microscopic Positive Margins in Cancer Surgery
      Wide local excision (WLE) is a common surgical intervention for solid tumors such as those in melanoma, breast, pancreatic, and gastrointestinal cancer. However, adequate margin assessment during WLE remains a significant challenge, resulting in surgical reinterventions to achieve adequate local control. Currently, no label-free imaging method is available for surgeons to examine the resection bed in vivo for microscopic residual cancer. Optical coherence tomography (OCT) enables real-time high-resolution imaging of ...
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    6. Intravascular magnetomotive optical coherence tomography of targeted early-stage atherosclerotic changes in ex vivo hyperlipidemic rabbit aortas

      Intravascular magnetomotive optical coherence tomography of targeted early-stage atherosclerotic changes in ex vivo hyperlipidemic rabbit aortas
      ...otic changes in ex vivo hyperlipidemic rabbit aortas 1. Jongsik Kim^1^1, 2. Adeel Ahmad^2, 3. Joanne Li^3, 4. Marina Marjanovic^1,3, 5. Eric J. Chaney^1, 6. Kenneth S. Suslick^1,4 and 7. Stephen A. Boppart^1,2,3,5,* Arti...
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    7. Feature Of The Week 10/12/14: University of Illinois at Urbana-Champaign Investigates PS-OCT with Ultimate Aim of Intraoperative Breast Cancer Tumor Margin Assessment

      Feature Of The Week 10/12/14: University of Illinois at Urbana-Champaign Investigates PS-OCT with Ultimate Aim of Intraoperative Breast Cancer Tumor Margin Assessment
      Successful treatment of breast cancer typically requires surgical removal of the tumor. Optical coherence tomography (OCT) has been previously developed for real-time imaging of the surgical margin. However, it can be difficult to distinguish between normal stromal tissue and cancer tissue based on scattering intensity and structure alone. Polarization-sensitive optical coherence tomography (PS-OCT) is sensitive to form birefringence of biological tissue. We report on the development of a high-speed PS-OCT ...
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    8. Long-term time-lapse multimodal intravital imaging of regeneration and bone-marrow-derived cell dynamics in skin (World Scientific)

      Long-term time-lapse multimodal intravital imaging of regeneration and bone-marrow-derived cell dynamics in skin (World Scientific)
      ...ence and Technology, University of Illinois at Urbana-Champaign, 405 N. Mathews Avenue, Urbana, IL 61801, USA Marina Marjanovic Beckman Institute for Advanced Science and Technology, University of Illinois at Urbana-Ch...
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    9. Magnetomotive Optical Coherence Tomography for the Assessment of Atherosclerotic Lesions Using αvβ 3 Integrin-Targeted Microspheres

      Magnetomotive Optical Coherence Tomography for the Assessment of Atherosclerotic Lesions Using αvβ 3 Integrin-Targeted Microspheres
      Purpose We investigated the early-stage fatty streaks/plaques detection using magnetomotive optical coherence tomography (MM-OCT) in conjunction with v 3 integrin-targeted magnetic microspheres (MSs). The targeting of functionalized MSs was investigated by perfusing ex vivo aortas from an atherosclerotic rabbit model in a custom-designed flow chamber at physiologically relevant pulsatile flow rates and pressures. Procedures Aortas were extracted and placed in a flow chamber. Magnetic MS contrast agents were perfused ...
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    10. Three-dimensional Optical Coherence Tomography for Optical Biopsy of Lymph Nodes and Assessment of Metastatic Disease

      Three-dimensional Optical Coherence Tomography for Optical Biopsy of Lymph Nodes and Assessment of Metastatic Disease
      ...psy of Lymph Nodes and Assessment of Metastatic Disease Renu John PhD, Steven G. Adie PhD, Eric J. Chaney BS, Marina Marjanovic PhD, Krishnarao V. Tangella MD, Stephen A. Boppart MD, PhD Translational Research and Biomar...
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    11. 4th Biophotonics Summer School at University of Illinois at Urbana-Champaign May 21st - June 1st, 2012

      4th Biophotonics Summer School at University of Illinois at Urbana-Champaign May 21st - June 1st, 2012
      The 4th Biophotonics Summer School, funded in part by the Network for Computational Nanotechnology (a resource supported by the National Science Foundation), and the University of Illinois Imaging Initiative, will take place at the University of Illinois at Urbana-Champaign, May 21- June 1, 2012. This is a two-week event aimed at training graduate students and post-doctoral associates with research interests at the interface between optics, biomedicine, and nanotechnology. The School ...
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    12. 1-15 of 15
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  2. About Marina Marjanovic

    Marina Marjanovic

    Marina Marjanovic is at the Beckman Institute for Advanced Science and Technology at the University of Illinois at Urbana–Champaign.