1. Maria M. Karabut

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    1. Mentioned In 11 Articles

    2. Multimodal optical coherence tomography for in vivo imaging of brain tissue structure and microvascular network at glioblastoma

      Multimodal optical coherence tomography for in vivo imaging of brain tissue structure and microvascular network at glioblastoma
      In the case of infiltrative brain tumors the surgeon faces difficulties in determining their boundaries to achieve total resection. The aim of the investigation was to evaluate the performance of multimodal OCT (MM OCT) for differential diagnostics of normal brain tissue and glioma using an experimental model of glioblastoma. The spectral domain OCT device that was used for the study provides simultaneously two modes: cross-polarization and microangiographic OCT. The comparative ...
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    3. Multimodal Optical Coherence Tomography in Visualization of Brain Tissue Structure at Glioblastoma (Experimental Study)

      Multimodal Optical Coherence Tomography in Visualization of Brain Tissue Structure at Glioblastoma (Experimental Study)
      The aim of the investigation was to evaluate the performance of multimodal OCT (MM OCT) for differential diagnostics of normal and diseased brain tissue using an experimental model of glioblastoma. Materials and Methods. The spectral domain MM OCT device developed at the Institute of Applied Physics of the Russian Academy of Sciences (Nizhny Novgorod, Russia) was used for the study. It provides two modes of investigation: cross-polarization OCT (CP OCT ...
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    4. Vessel-contrast enhancement in label-free optical coherence angiography based on phase and amplitude speckle variability

      Vessel-contrast enhancement in label-free optical coherence angiography based on phase and amplitude speckle variability
      Recently proposed in vivo label-free optical coherence angiography techniques based on phase and amplitude speckle variability often require additional signal pre- and post processing operations to enhance vessel-contrast. We observe here 1) contrast enhancement by optimizing the signal normalization/weighing before processing; 2) algorithm based on Kasai estimator for phase compensation between processed A-scans to reduce masking role of motion artifacts; and 3) image projection through the imaging depth for ...
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    5. The Development of the Methodology of Monitoring Experimental Tumors Using Multimodal Optical Coherence Tomography: the Choice of an Optimal Tumor Model

      The Development of the Methodology of Monitoring Experimental Tumors Using Multimodal Optical Coherence Tomography: the Choice of an Optimal Tumor Model
      The objective of the research was to study the features of transplantation, growth and visualization of experimental tumors of animals, using multi-functional optical coherence tomography (OCT) to develop the methodology of evaluation of individual tumor response to anti-cancer therapy. Materials and Methods. The research was carried out using an experimental high-speed spectral-domain multimodal OCT system developed at the Institute of Applied Physics of the Russian Academy of Sciences (Russia). The ...
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    6. Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers

      Combined use of fluorescence cystoscopy and cross-polarization OCT for diagnosis of bladder cancer and correlation with immunohistochemical markers
      The combined use of fluorescence cystoscopy and cross-polarization optical coherence tomography (CP OCT) with quantitative estimation of the OCT signal was assessed in 92 bladder zones. It demonstrated the diagnostic accuracy in detecting superficial bladder cancer of 93.6%, sensitivity 96.4%, specificity 92.1%, positive predictive value 87% and negative predictive value 97.9%. Quantitative estimation of OCT signal standard deviation in cross-polarization (CP OCT SD index) makes the ...
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    7. Feature Of The Week 3/13/11: Russian Scientists Investigate Cross Polarization OCT for Early Bladder Cancer Detection

      Feature Of The Week 3/13/11: Russian Scientists Investigate Cross Polarization OCT for Early Bladder Cancer Detection
      Feature Of The Week 3/13/11: This week OCT News has another exciting “Feature Of The Week” presentation of exciting scientific results on the use of co- and cross-polarization OCT information applied to early bladder cancer detection.  The work is from the prestigious Institute of Applied and Fundamental Medicine at the Nizhny Novgorod State Medical Academy and the Institute of Applied Physics of the Russian Academy of Sciences, Nizhny ...
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    8. Advantages of cross-polarization endoscopic optical coherence tomography in diagnosis of bladder neoplasia

      Advantages of cross-polarization endoscopic optical coherence tomography in diagnosis of bladder neoplasia
      ...en, E. Duco Jansen ABSTRACT REFERENCES (9) N. D. Gladkova, E. V. Zagaynova, O. S. Streltsova, E. B. Kiseleva, M. M. Karabut, L. B. Snopova, E. E. Yunusova, and E. Tararova Nizhny Novgorod State Medical Academy (Russian F...
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    9. Application of optical coherence tomography in the diagnosis of mucositis in patients with head and neck cancer during a course of radio(chemo)therapy

      Objective Mucositis is the most common oral complication of non-surgical therapy (chemotherapy, radiotherapy, and radio(chemo)therapy) in patients with head and neck cancer. Growing evidence indicates that more aggressive treatment regimens improve local tumor control and the survival of patients with locally advanced head and neck cancer. However combined therapy approaches are associated with higher acute toxicity. Currently there are no in vivo methods to visualize microscopic changes of ...
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    10. 1-11 of 11
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  2. About Maria M. Karabut

    Maria M. Karabut

    Maria M. Karabut studied biophysics at the N.I. Lobachevsky State University of Nizhny Novgorod, Russia, where she received her Diploma in 2008. Currently, she is working in the OCT group, Institute of Applied and Fundamental Medicine, Nizhny Novgorod State Medical Academy. Her research interests include optical coherence tomography, polarization microscopic, handling of optical images and interaction of laser radiation with different biological materials.