1. Makoto Araie

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    1. Mentioned In 21 Articles

    2. Comparison of post‐stent optical coherence tomography findings among three subtypes of calcified culprit plaques in patients with acute coronary syndrome

      Comparison of post‐stent optical coherence tomography findings among three subtypes of calcified culprit plaques in patients with acute coronary syndrome
      Objectives To compare the postprocedural optical coherence tomography (OCT) findings and in‐hospital outcomes among the three subtypes of calcified plaques: eruptive calcified nodules, superficial calcific sheet, and calcified protrusion. Background Recently, three subtypes of calcified culprit plaques were reported in patients with acute coronary syndrome (ACS). How these subtypes respond to stenting is unknown. Methods ACS patients with calcified plaque at the culprit lesion were selected from our database ...
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    3. Using Deep Learning and transform learning to accurately diagnose early-onset glaucoma from macular optical coherence tomography images

      Using Deep Learning and transform learning to accurately diagnose early-onset glaucoma from macular optical coherence tomography images
      Purpose To construct and evaluate a Deep Learning (DL) model to diagnose early glaucoma from spectral domain optical coherence tomography (SD-OCT) images. Design AI diagnostic tool development, evaluation, and comparison Methods Setting: multiple institutional practices. Study population Pre-training data consisted of 4316 OCT images (RS3000, Nidek) from 1565 eyes with open angle glaucoma (OAG) irrespective of the stage of glaucoma and 193 normal eyes. Training data included OCT-1000/2000 (Topcon ...
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    4. Glaucomatous changes in lamina pores shape within the lamina cribrosa using wide bandwidth, femtosecond mode-locked laser OCT

      Glaucomatous changes in lamina pores shape within the lamina cribrosa using wide bandwidth, femtosecond mode-locked laser OCT
      Purpose The lamina cribrosa (LC) is known to play a critical role in the pathogenesis of glaucoma. Although it has been reported that striae-shaped or slit-shaped lamina pores are more frequent in eyes with primary open angle glaucoma (POAG), this observation is based only on fundus photography. The primary object of this study is to perform layer-by-layer comparisons of the shape of lamina pores within the LC in vivo. Design ...
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    5. Validating the usefulness of the 'Random Forests’ classifier to diagnose early glaucoma with optical coherence tomography

      Validating the usefulness of the 'Random Forests’ classifier to diagnose early glaucoma with optical coherence tomography
      Purpose To validate the usefulness of the 'Random Forests classifier to diagnose early glaucoma with spectral domain optical coherence tomography (SD-OCT). Method Design: Comparison of diagnostic algorithms Setting: multiple institutional practice Study participants Training dataset included 94 eyes of 94 open angle glaucoma (OAG) patients and 84 eyes of 84 normal subjects and testing dataset included 114 eyes of 114 OAG patients and 82 eyes of 82 normal subjects. In ...
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    6. Correlation between Lamina Cribrosa Tilt Angles, Myopia and Glaucoma Using OCT with a Wide Bandwidth Femtosecond Mode-Locked Laser

      Correlation between Lamina Cribrosa Tilt Angles, Myopia and Glaucoma Using OCT with a Wide Bandwidth Femtosecond Mode-Locked Laser
      Purpose To measure horizontal and vertical lamina cribrosa (LC) tilt angles and investigate associated factors using prototype optical coherence tomography (OCT) with a broad wavelength laser light source. Design Cross sectional study. Methods Twenty-eight no glaucoma eyes (from 15 subjects) and 25 glaucoma eyes (from 14 patients) were enrolled. A total of 300 optic nerve head B-scans were obtained in 10 m steps and the inner edge of Bruch's ...
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    7. Three-dimensional optic nerve head images using optical coherence tomography with a broad bandwidth, femtosecond, and mode-locked laser

      Three-dimensional optic nerve head images using optical coherence tomography with a broad bandwidth, femtosecond, and mode-locked laser
      Purpose The aim of this study was to demonstrate the fine laminar structure of the optic nerve head (ONH), in vivo, using a broad wavelength, ultra-high resolution, and optically coherent tomography (OCT) system. Methods This high-resolution OCT system, based on a 200 nm bandwidth spectrometer and an 8 femtosecond ultra-short, mode-locked, coherent laser light source, enabled in vivo cross-sectional ONH imaging with 2.0 m axial resolution. A total of ...
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    8. Discriminating between Glaucoma and Normal Eyes Using Optical Coherence Tomography and the ‘Random Forests’ Classifier

      Discriminating between Glaucoma and Normal Eyes Using Optical Coherence Tomography and the ‘Random Forests’ Classifier
      Purpose To diagnose glaucoma based on spectral domain optical coherence tomography (SD-OCT) measurements using the Random Forests method. Methods SD-OCT was conducted in 126 eyes of 126 open angle glaucoma (OAG) patients and 84 eyes of 84 normal subjects. The Random Forests method was then applied to discriminate between glaucoma and normal eyes using 151 OCT parameters including thickness measurements of circumpapillary retinal nerve fiber layer (cpRNFL), the macular RNFL ...
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    9. Iridotrabecular contact observed using anterior segment three-dimensional OCT in eyes with a shallow peripheral anterior chamber

      Iridotrabecular contact observed using anterior segment three-dimensional OCT in eyes with a shallow peripheral anterior chamber
      Purpose: To evaluate the prevalence and range of iridotrabecular contact (ITC) in eyes with a shallow peripheral anterior chamber (AC) by using anterior segment swept-source optical coherence tomography (AS-SS-OCT) and to compare the results with those obtained with ultrasound biomicroscopy (UBM) and gonioscopy. Methods: Forty-three shallow peripheral AC eyes in 43 consecutive patients underwent gonioscopy. Cross-sectional images throughout the angle circumference (i.e., 360 degrees) were obtained with AS-SS-OCT (SS-1000 ...
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    10. Fundus oculi observation device, ophthalmologic image processing device, and program

      Fundus oculi observation device, ophthalmologic image processing device, and program
      A fundus oculi observation device capable of defining which part in the result of analysis of the layer thickness of a fundus oculi is a part obtained by analyzing a vascular region is provided. A fundus oculi observation device 1 forms a plurality of tomographic images G1-Gm of a fundus oculi Ef. A layer thickness distribution calculator 231 calculates layer thickness distribution of the fundus oculi Ef in a cross ...
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    11. Reproducibility of Thickness Measurements of Macular Inner Retinal Layers Using SD-OCT with or without Correction of Ocular Rotation

      Reproducibility of Thickness Measurements of Macular Inner Retinal Layers Using SD-OCT with or without Correction of Ocular Rotation
      Purpose. To evaluate the inter-visit reproducibility of spectral-domain optical coherence tomography (SD-OCT) measurement of the macular retinal nerve fiber layer thickness (mRNFLT), combined ganglion cell layer and inner plexiform layer (GCL+IPL) thickness, and ganglion cell complex (GCC) thicknesses (sum of mRNFLT and GCL+IPL thicknesses) compared with that of circumpapillary RNFLT (cpRNFLT) and the effect of ocular rotation on reproducibility. Methods. SD-OCT imaging was performed twice on different days ...
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    12. Test–retest variability in structural parameters measured with glaucoma imaging devices

      Test–retest variability in structural parameters measured with glaucoma imaging devices
      In addition to classical stereo-disc photography, various glaucoma imaging devices were developed in the last two decades to quantitatively measure and record glaucoma-related structural parameters of the eye. In determining whether or not the glaucomatous damage progressed from baseline and in estimating the number of test results optimal frequency needed to confirm disease progression, information relating to the testretest variability of measurement results provided by each imaging device is indispensable ...
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    13. Spectral-Domain Optical Coherence Tomography of β-zone Peripapillary Atrophy: Influence of Myopia and Glaucoma

      Spectral-Domain Optical Coherence Tomography of β-zone Peripapillary Atrophy: Influence of Myopia and Glaucoma
      Purpose: To investigate the influence of glaucoma and myopia on the cross-sectional configuration of β-zone peripapillary atrophy (PPA-β) using spectral-domain optical coherence tomography (SD-OCT). Methods: Among 100 eyes of 100 consecutive patients with POAG regardless of intraocular pressure level and 100 eyes of 100 normal subjects, cross-sectional B-scan images of PPA-β obtained with SD-OCT were evaluated. PPA bed configurations were classified and associated factors were studied with multivariate analysis. Results ...
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    14. Noninvasive Observations of Peripheral Angle in Eyes After Penetrating Keratoplasty Using Anterior Segment Fourier-Domain Optical Coherence Tomography

      Noninvasive Observations of Peripheral Angle in Eyes After Penetrating Keratoplasty Using Anterior Segment Fourier-Domain Optical Coherence Tomography
      Purpose: To examine iridotrabecular contact (ITC) as a peripheral anterior synechia (PAS) of patients who underwent penetrating keratoplasty (PKP) using anterior segment Fourier-domain optical coherence tomography (OCT). Methods: Retrospective, observational case series. ITC, ITC index, and ITC area of 60 eyes of 52 patients who underwent PKP at the Department of Ophthalmology in the University of Tokyo Hospital (mean follow-up time 102.8 +/- 116.1 months postoperation) were calculated using ...
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    15. Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures

      Effects of Age, Sex, and Axial Length on the Three-Dimensional Profile of Normal Macular Layer Structures
      Purpose. To identify sex-related differences and age-related changes in individual retinal layer thicknesses in a population of healthy eyes across the lifespan, using spectral domain optical coherence tomography (SD-OCT). Methods. In seven institutes in Japan, mean thicknesses of the retinal nerve fiber layer (RNFL), ganglion cell layer (GCL), inner plexiform layer (IPL), inner nuclear layer (INL), outer plexiform layer (OPL), outer nuclear layer (ONL), photoreceptor inner segment (IS), and photoreceptor ...
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  2. About Makoto Araie

    Makoto Araie

    Makoto Araie is a Professor and Chairman of the Department of Ophthalmology at The University of Tokyo Graduate School of Medicine.