1. LuEsther T. Mertz Retinal Research Center

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    1. Mentioned In 72 Articles

    2. Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium

      Explore IOVS Journal Ophthalmology
      Hyperreflective Foci, Optical Coherence Tomography Progression Indicators in Age-Related Macular Degeneration, Include Transdifferentiated Retinal Pigment Epithelium
      Purpose: By optical coherence tomography (OCT) imaging, hyperreflective foci (HRF) indicate progression risk for advanced age-related macular degeneration (AMD) and are in part attributable to ectopic retinal pigment epithelium (RPE). We hypothesized that ectopic RPE are molecularly distinct from in-layer cells and that their cross-retinal course follows Mller glia. Methods: In clinical OCT (61 eyes, 44 patients with AMD, 79.4 7.7 years; 29 female; follow-up = 4.7 0 ...
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      Mentions: University of Alabama LuEsther T. Mertz Retinal Research Center

    3. Suspended Scattering Particles in Motion May Influence Optical Coherence Tomography Angiography Vessel Density Metrics in Eyes with Diabetic Macular Edema

      Explore LWW Online Ophthalmology
      Suspended Scattering Particles in Motion May Influence Optical Coherence Tomography Angiography Vessel Density Metrics in Eyes with Diabetic Macular Edema
      Purpose: To study the effect of the suspended scattering particles in motion (SSPiM) on optical coherence tomography angiography (OCTA) vessel density metrics in eyes with diabetic macular edema (DME) Methods: Thirty-four eyes with DME from 27 patients (16 males and 11 females, 61.4 9.6 years) with DME were included in this retrospective cohort study. Among these eyes, 19 (55.9%) showed the SSPiM artifact on OCTA. All participants ...
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      Mentions: LuEsther T. Mertz Retinal Research Center

    4. Clinical utility of morphofunctional correlation of microperimetry and optical coherence tomography

      Explore LWW Online Ophthalmology
      Clinical utility of morphofunctional correlation of microperimetry and optical coherence tomography
      Purpose: To demonstrate the clinical and research value of a simplified technique enabling alignment of functional microperimetry data with retinal structure imaged by eye-tracked optical coherence tomography (OCT) in eyes with macular disease. Methods: Normal and diseased eyes underwent sequential Spectralis OCT macular raster scans and Macular Integrity Assessment (MAIA) microperimetry using both standard central 10 analysis and custom scan patterns. The microperimetry data were imported into Spectralis research software ...
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      Mentions: Columbia University LuEsther T. Mertz Retinal Research Center University of Tsukuba

    6. Macroaneurysms Associated With Congenital Retinal Macrovessels

      Explore LWW Online Ophthalmology
      Macroaneurysms Associated With Congenital Retinal Macrovessels
      Purpose: Congenital retinal macrovessels are large aberrant retinal blood vessels that cross the horizontal raphe and can traverse the central macula. Using multimodal imaging and optical coherence tomography angiography, we describe 2 cases of congenital retinal macrovessel associated with macroaneurysms. Methods: Two patients presented for evaluation and were found to have congenital retinal macrovessels associated with macroaneurysms. Color photography, optical coherence tomography, fundus autofluorescence fluorescein angiography, and optical coherence tomography ...
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      Mentions: Columbia University University of São Paulo LuEsther T. Mertz Retinal Research Center

    7. Optical Coherence Tomography Angiography in a Patient With Diabetes and Preretinal Neovascularization

      Explore The JAMA Network Ophthalmology
      Optical Coherence Tomography Angiography in a Patient With Diabetes and Preretinal Neovascularization
      A 39-year-old patient with type 2 diabetes (diagnosed in 1996) presented for an evaluation of bilateral proliferative diabetic retinopathy that had been treated previously with panretinal photocoagulation. His visual acuity was 20/25 OD. Examination by ophthalmoscopy showed scattered dot-blot intraretinal hemorrhages and an inferotemporal preretinal neovascular frond ( Figure , A). Optical coherence tomography angiography was also performed ( Figure , B).
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      Mentions: LuEsther T. Mertz Retinal Research Center

    8. Optical coherence tomography en face analysis of the posterior vitreous reveal topographic relationships between premacular bursa, prevascular fissures and cisterns

      Explore ScienceDirect Ophthalmology
      Optical coherence tomography en face analysis of the posterior vitreous reveal topographic relationships between premacular bursa, prevascular fissures and cisterns
      Purpose To characterize the topographic relationships among vitreous structures including the premacular bursa, prevascular vitreous fissures, cisterns and lacunae in healthy subjects using en face and cross-sectional swept-source optical coherence tomography (SS-OCT). Design Prospective comparative study. Subjects Sixty eyes of 60 healthy subjects (age range = 4 35 years). Eyes of individuals younger than 20 years (n= 29) were compared with eyes of individuals aged 20 years or older (n=31 ...
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      Mentions: LuEsther T. Mertz Retinal Research Center University of Zurich

    9. EVALUATION OF SEGMENTAL RETINAL ARTERITIS WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Explore LWW Online Ophthalmology
      EVALUATION OF SEGMENTAL RETINAL ARTERITIS WITH OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To describe the vascular anatomy and intraluminal flow characteristics of segmental retinal arteritis (SRA) using structural and angiographic optical coherence tomography (OCT). Methods: Retrospective case series of consecutive patients presenting with SRA. All patients were evaluated at presentation with fundus photography, spectral domain OCT, and OCT angiography. One patient was imaged with dense B-scan OCT angiography. Results: Three eyes of three male patients were evaluated. All examinations were consistent ...
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      Mentions: Columbia University Stanford University LuEsther T. Mertz Retinal Research Center

    10. Filigree vascular pattern in Combined Hamartoma of Retina and Retinal Pigment Epithelium on Optical Coherence Tomography Angiography

      Explore ScienceDirect Ophthalmology
      Filigree vascular pattern in Combined Hamartoma of Retina and Retinal Pigment Epithelium on Optical Coherence Tomography Angiography
      Objective To evaluate the vascular structure within combined hamartoma of retina and retinal pigment epithelium (CHRRPE) lesions using optical coherence tomography angiography (OCT-A). Design: Multicentre retrospective observational analysis Subjects: 20 eyes of patients diagnosed with CHRRPE Methods Retrospective analysis of color fundus photographs, optical coherence tomography (OCT) and OCT-A of 20 eyes with CHRRPE. Morphological characteristics of CHRRPE and the OCT features were correlated with the density of the filigree ...
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      Mentions: L V Prasad Eye Institute LuEsther T. Mertz Retinal Research Center University of Sydney

    11. Optical Coherence Tomography Angiography of Retinal-Choroidal Anastomosis in Toxoplasmosis Chorioretinitis

      Explore The JAMA Network Ophthalmology
      Optical Coherence Tomography Angiography of Retinal-Choroidal Anastomosis in Toxoplasmosis Chorioretinitis
      A young adult was examined for follow-up of toxoplasmosis chorioretinitis that was diagnosed and treated during early childhood. Two subsequent flare-ups were treated with atovaquone, combined trimethoprim and sulfamethoxazole, and oral prednisone. Visual acuity was 20/20 OD. Ophthalmoscopic examination results demonstrated an inactive temporal chorioretinal scar with an apparent retinal-choroidal anastomosis ( Figure ). Optical coherence tomography angiography was performed through the anastomosis. Enface images ( Figure ) of the retinal and choroidal ...
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      Mentions: LuEsther T. Mertz Retinal Research Center

    12. Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects

      Explore BJO Online Ophthalmology
      Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects
      Background/Aims Hydroxychloroquine (HCQ) retinopathy may result in severe and irreversible vision loss, emphasising the importance of screening and early detection. The purpose of this study is to report the novel finding of early optical coherence tomography (OCT) abnormalities due to HCQ toxicity that may develop in the setting of normal Humphrey visual field (HVF) testing. Methods Data from patients with chronic HCQ exposure was obtained from seven tertiary care ...
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      Mentions: Case Western Reserve University LuEsther T. Mertz Retinal Research Center Tufts University

    13. Imaging Of Pigment Epithelial Detachments With Optical Coherence Tomography Angiography

      Explore LWW Online Ophthalmology
      Imaging Of Pigment Epithelial Detachments With Optical Coherence Tomography Angiography
      Purpose: To investigate the utility of optical coherence tomography angiography (OCTA) for detecting pathologic vascularization within pigment epithelial detachments (PEDs). Methods: This was a retrospective, cross-sectional, consecutive case series. Multimodal imaging (structural OCT, fluorescein, and indocyanine green angiography) was used as the gold standard to classify PEDs as nonvascularized or vascularized. Optical coherence tomography angiography imaging of the PED was subsequently and independently evaluated to classify PEDs as vascularized or ...
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      Mentions: Singapore Eye Research Institute LuEsther T. Mertz Retinal Research Center University of Western Australia

    14. Type 3 neovascularisation: long-term analysis of visual acuity and optical coherence tomography anatomical outcomes

      Explore BJO Online Ophthalmology
      Type 3 neovascularisation: long-term analysis of visual acuity and optical coherence tomography anatomical outcomes
      Background To investigate the long-term visual and optical coherence tomography (OCT) anatomical outcomes of type 3 neovascularisation (NV) and to identify any baseline predictors of poor outcomes. Methods In this retrospective study, patients diagnosed with treatment nave type 3 NV were identified and categorised into two groups: good or poor vision based on final vision at 1year. Baseline demographic features and visual acuity (VA) and baseline and 1-year spectral domain ...
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      Mentions: LuEsther T. Mertz Retinal Research Center UCLA

    15. Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Explore ScienceDirect Ophthalmology
      Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography
      Purpose To describe a method to obtain images of the choroid using conventional spectral-domain (SD) optical coherence tomography (OCT) and to evaluate choroidal thickness measurements using these images. Design Observational case series. Methods The images were obtained by positioning the SD OCT device close enough to the eye to obtain an inverted representation of the fundus in healthy volunteers who did not have pupillary dilation. Seven sections, each comprised of ...
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      Mentions: LuEsther T. Mertz Retinal Research Center

    16. The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy

      Explore IOVS Journal Ophthalmology
      The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy
      Purpose : Histologic details of progression routes to geographic atrophy (GA) in AMD are becoming available through optical coherence tomography (OCT). We studied the origins and evolution of an OCT signature called plateau in eyes with GA and suggested a histologic correlate. Methods : Serial eye-tracked OCT scans and multimodal imaging were acquired from eight eyes of seven patients with GA and plateau signatures over a mean follow-up of 7.7 years ...
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      Mentions: University of Alabama LuEsther T. Mertz Retinal Research Center
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  4. About LuEsther T. Mertz Retinal Research Center

    LuEsther T. Mertz Retinal Research Center

    LuEsther T. Mertz Retinal Research Center mission is to ensure the highest quality of care for sufferers of retinal disorders. With that goal in mind, the center is involved in a number of efforts that span the spectrum of research, educational programs and outreach/public awareness efforts. The center is located at the Manhattan Eye, Ear & Throat Hospital and is under the directorship of Dr. Lawrence Yannuzzi. Funding for the center is provided by The Macula Foundation, Inc. and study grants.

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