1. LuEsther T. Mertz Retinal Research Center

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    1. Mentioned In 63 Articles

    2. Optical Coherence Tomography Angiography of Retinal-Choroidal Anastomosis in Toxoplasmosis Chorioretinitis

      Explore The JAMA Network Ophthalmology
      Optical Coherence Tomography Angiography of Retinal-Choroidal Anastomosis in Toxoplasmosis Chorioretinitis
      A young adult was examined for follow-up of toxoplasmosis chorioretinitis that was diagnosed and treated during early childhood. Two subsequent flare-ups were treated with atovaquone, combined trimethoprim and sulfamethoxazole, and oral prednisone. Visual acuity was 20/20 OD. Ophthalmoscopic examination results demonstrated an inactive temporal chorioretinal scar with an apparent retinal-choroidal anastomosis ( Figure ). Optical coherence tomography angiography was performed through the anastomosis. Enface images ( Figure ) of the retinal and choroidal ...
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      Mentions: LuEsther T. Mertz Retinal Research Center K. Bailey Freund

    3. Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects

      Explore BJO Online Ophthalmology
      Early hydroxychloroquine retinopathy: optical coherence tomography abnormalities preceding Humphrey visual field defects
      Background/Aims Hydroxychloroquine (HCQ) retinopathy may result in severe and irreversible vision loss, emphasising the importance of screening and early detection. The purpose of this study is to report the novel finding of early optical coherence tomography (OCT) abnormalities due to HCQ toxicity that may develop in the setting of normal Humphrey visual field (HVF) testing. Methods Data from patients with chronic HCQ exposure was obtained from seven tertiary care ...
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      Mentions: Case Western Reserve University Jay S. Duker LuEsther T. Mertz Retinal Research Center

    4. Imaging Of Pigment Epithelial Detachments With Optical Coherence Tomography Angiography

      Explore LWW Online Ophthalmology
      Imaging Of Pigment Epithelial Detachments With Optical Coherence Tomography Angiography
      Purpose: To investigate the utility of optical coherence tomography angiography (OCTA) for detecting pathologic vascularization within pigment epithelial detachments (PEDs). Methods: This was a retrospective, cross-sectional, consecutive case series. Multimodal imaging (structural OCT, fluorescein, and indocyanine green angiography) was used as the gold standard to classify PEDs as nonvascularized or vascularized. Optical coherence tomography angiography imaging of the PED was subsequently and independently evaluated to classify PEDs as vascularized or ...
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      Mentions: Singapore Eye Research Institute LuEsther T. Mertz Retinal Research Center University of Western Australia

    5. Type 3 neovascularisation: long-term analysis of visual acuity and optical coherence tomography anatomical outcomes

      Explore BJO Online Ophthalmology
      Type 3 neovascularisation: long-term analysis of visual acuity and optical coherence tomography anatomical outcomes
      Background To investigate the long-term visual and optical coherence tomography (OCT) anatomical outcomes of type 3 neovascularisation (NV) and to identify any baseline predictors of poor outcomes. Methods In this retrospective study, patients diagnosed with treatment nave type 3 NV were identified and categorised into two groups: good or poor vision based on final vision at 1year. Baseline demographic features and visual acuity (VA) and baseline and 1-year spectral domain ...
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      Mentions: LuEsther T. Mertz Retinal Research Center UCLA K. Bailey Freund

    6. Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Explore ScienceDirect Ophthalmology
      Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography
      Purpose To describe a method to obtain images of the choroid using conventional spectral-domain (SD) optical coherence tomography (OCT) and to evaluate choroidal thickness measurements using these images. Design Observational case series. Methods The images were obtained by positioning the SD OCT device close enough to the eye to obtain an inverted representation of the fundus in healthy volunteers who did not have pupillary dilation. Seven sections, each comprised of ...
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      Mentions: Hideki Koizumi LuEsther T. Mertz Retinal Research Center Richard F. Spaide

    7. The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy

      Explore IOVS Journal Ophthalmology
      The Evolution of the Plateau, an Optical Coherence Tomography Signature Seen in Geographic Atrophy
      Purpose : Histologic details of progression routes to geographic atrophy (GA) in AMD are becoming available through optical coherence tomography (OCT). We studied the origins and evolution of an OCT signature called plateau in eyes with GA and suggested a histologic correlate. Methods : Serial eye-tracked OCT scans and multimodal imaging were acquired from eight eyes of seven patients with GA and plateau signatures over a mean follow-up of 7.7 years ...
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      Mentions: University of Alabama LuEsther T. Mertz Retinal Research Center Lawrence A. Yannuzzi

    8. Strip-based registration of serially acquired optical coherence tomography angiography

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      Strip-based registration of serially acquired optical coherence tomography angiography
      The visibility of retinal microvasculature in optical coherence tomography angiography (OCT-A) images is negatively affected by the small dimension of the capillaries, pulsatile blood flow, and motion artifacts. Serial acquisition and time-averaging of multiple OCT-A images can enhance the definition of the capillaries and result in repeatable and consistent visualization. We demonstrate an automated method for registration and averaging of serially acquired OCT-A images. Ten OCT-A volumes from six normal ...
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      Mentions: University of British Columbia LuEsther T. Mertz Retinal Research Center Marinko V. Sarunic

    9. CHOROIDAL BLOOD VESSELS IN RETINAL PIGMENT EPITHELIAL ATROPHY USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY

      Explore LWW Online Ophthalmology
      CHOROIDAL BLOOD VESSELS IN RETINAL PIGMENT EPITHELIAL ATROPHY USING OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY
      Purpose: To observe choroidal blood vessels in cases sharply demarcated with retinal pigment epithelium (RPE) atrophy at the macular area using en-face optical coherence tomography angiography (OCTA) and standard en-face optical coherence tomography (OCT). Methods: The retrospective study included 12 eyes (8 patients; 5 men, 3 women; average age, 64.3 years) with RPE atrophy seen by ophthalmoscopy. The macular areas with normal and atrophic RPE sections were examined using ...
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      Mentions: Hideki Koizumi Optovue LuEsther T. Mertz Retinal Research Center

    10. Evaluation of Segmentation of the Superficial and Deep Vascular Layers of the Retina By Optical Coherence Tomography Angiography Instruments in Normal Eyes

      Explore The JAMA Network Ophthalmology
      Evaluation of Segmentation of the Superficial and Deep Vascular Layers of the Retina By Optical Coherence Tomography Angiography Instruments in Normal Eyes
      Importance Correct attribution of vascular features in optical coherence tomography (OCT) angiography depends on accurate segmentation of retinal layers. Objective To evaluate the segmentation of retinal layers among 3 OCT angiography instruments in the central macula, an area where the superficial and deep vascular plexuses terminate. Design, Setting, and Participants A retrospective review of a representative OCT angiogram from 1 patient and an evaluation of the vascular pattern in an ...
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      Mentions: Optovue Topcon Medical Systems University of Alabama

    11. Choroidal Osteoma Deossification Visualized by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography

      Explore Healio.com Ophthalmology
      Choroidal Osteoma Deossification Visualized by Enhanced Depth Imaging Spectral-Domain Optical Coherence Tomography
      Choroidal osteoma (CO) is a rare, benign ossifying lesion of the choroid found in otherwise healthy patients. Although associated with good visual prognosis, tumor deossification in choroidal osteoma has been linked with vision loss, presumably due to overlying photoreceptor degeneration. Here the authors present a case of CO in an elderly male demonstrating tumor deossification and photoreceptor atrophy during a 3-year follow-up using enhanced depth imaging optical coherence tomography (EDI-OCT ...
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      Mentions: LuEsther T. Mertz Retinal Research Center

    12. VOLUME-RENDERED ANGIOGRAPHIC AND STRUCTURAL OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF MACULAR TELANGIECTASIA TYPE 2

      Explore LWW Online Ophthalmology
      VOLUME-RENDERED ANGIOGRAPHIC AND STRUCTURAL OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY OF MACULAR TELANGIECTASIA TYPE 2
      Purpose: To evaluate multimodal imaging including volume-rendered angiographic and structural optical coherence tomography of macular telangiectasia Type 2 (MacTel2) for right-angle vein complexes, macular cavitations, and signs of deeper retinal vascular invasion. Methods: Retrospective review of imaging performed in a community-based retinal referral center. The eyes were scanned using optical coherence tomography using split-spectrum amplitude-decorrelation techniques to derive flow information. These data were extracted and used to create volume-rendered images ...
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      Mentions: Columbia University LuEsther T. Mertz Retinal Research Center Richard F. Spaide

    13. Fractal Dimensional Analysis of Optical Coherence Tomography Angiography in Eyes With Diabetic Retinopathy

      Explore IOVS Journal Ophthalmology
      Fractal Dimensional Analysis of Optical Coherence Tomography Angiography in Eyes With Diabetic Retinopathy
      Purpose : We used fractal dimensional analysis to analyze retinal vascular disease burden in eyes with diabetic retinopathy using spectral-domain optical coherence tomography angiography (OCTA). Methods : A retrospective study was performed of 13 eyes with diabetic retinopathy without diabetic macular edema and 56 control eyes. Optical coherence tomography angiography images were acquired using the RTVue XR Avanti. Automated segmentation was obtained through the superficial and deep capillary plexuses for each eye ...
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      Mentions: Optovue Columbia University LuEsther T. Mertz Retinal Research Center

    14. Optical coherence tomography angiography of type 3 neovascularisation in age-related macular degeneration after antiangiogenic therapy

      Explore BJO Online Ophthalmology
      Optical coherence tomography angiography of type 3 neovascularisation in age-related macular degeneration after antiangiogenic therapy
      Background/aims To assess the microvascular response of type 3 neovascularisation secondary to age-related macular degeneration (AMD) after antivascular endothelial growth factor (anti-VEGF) therapy using optical coherence tomography angiography (OCTA). Methods Consecutive patients diagnosed with AMD and type 3 neovascularisation based on clinical examination, structural optical coherence tomography and fluorescein angiography when available were retrospectively evaluated. En face OCTA imaging (33 mm scans) with quantitative microvascular analysis was performed at ...
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      Mentions: Singapore Eye Research Institute LuEsther T. Mertz Retinal Research Center UCLA

    15. Optical Coherence Tomography Evaluation of Valsalva-Induced Suprachoroidal Hemorrhage

      Explore Healio.com Ophthalmology
      Optical Coherence Tomography Evaluation of Valsalva-Induced Suprachoroidal Hemorrhage
      Suprachoroidal hemorrhage is typically observed in patients with hypotony in the context of intraocular surgery and trauma. We report a rare presentation of suprachoroidal hemorrhage associated with emesis (Valsalva maneuver) in a myopic patient with few other identifiable risk factors. This diagnosis was confirmed with wide-field fundus photography and B-scan ultrasound and was localized to the suprachoroidal space using both enhanced depth and swept-source optical coherence tomography imaging. This case ...
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      Mentions: LuEsther T. Mertz Retinal Research Center University of Miami

    16. A Comparison Between Optical Coherence Tomography Angiography and Fluorescein Angiography for the Imaging of Type 1 Neovascularization

      Explore IOVS Journal Ophthalmology
      A Comparison Between Optical Coherence Tomography Angiography and Fluorescein Angiography for the Imaging of Type 1 Neovascularization
      Purpose : To determine the sensitivity of the combination of optical coherence tomography angiography (OCTA) and structural optical coherence tomography (OCT) for detecting type 1 neovascularization (NV) and to determine significant factors that preclude visualization of type 1 NV using OCTA. Methods : Multicenter, retrospective cohort study of 115 eyes from 100 patients with type 1 NV. A retrospective review of fluorescein (FA), OCT, and OCTA imaging was performed on a consecutive ...
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      Mentions: Massachusetts Institute of Technology Jay S. Duker LuEsther T. Mertz Retinal Research Center
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  4. About LuEsther T. Mertz Retinal Research Center

    LuEsther T. Mertz Retinal Research Center

    LuEsther T. Mertz Retinal Research Center mission is to ensure the highest quality of care for sufferers of retinal disorders. With that goal in mind, the center is involved in a number of efforts that span the spectrum of research, educational programs and outreach/public awareness efforts. The center is located at the Manhattan Eye, Ear & Throat Hospital and is under the directorship of Dr. Lawrence Yannuzzi. Funding for the center is provided by The Macula Foundation, Inc. and study grants.

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