1. Ludwig Maximilian University of Munich

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    1. Mentioned In 168 Articles

    2. In vivo examination of healthy human skin after short-time treatment with moisturizers using confocal Raman spectroscopy and optical coherence tomography: Preliminary observations

      In vivo examination of healthy human skin after short-time treatment with moisturizers using confocal Raman spectroscopy and optical coherence tomography: Preliminary observations
      Skin is our barrier against environmental damage. Moisturizers are widely used to increase hydration and barrier integrity of the skin; however, there are contrasting observations on their in vivo effects in real-life settings. In cosmetic studies, corneometers and tewameters are traditionally used to assess skin hydration. In this study, two novel noninvasive diagnostic techniques, optical coherence tomography (OCT) and confocal Raman spectroscopy, were used to analyze stratum corneum and epidermal ...
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    3. Retinal Optical Coherence Tomography in Neuromyelitis Optica

      Retinal Optical Coherence Tomography in Neuromyelitis Optica
      Background and objectives: To determine optic nerve and retinal damage in aquaporin-4 antibody (AQP4-IgG)-seropositive neuromyelitis optica spectrum disorders (NMOSD) in a large international cohort after previous studies have been limited by small and heterogeneous cohorts. Methods: The cross-sectional Collaborative Retrospective Study on retinal optical coherence tomography (OCT) in neuromyelitis optica collected retrospective data from 22 centers. Of 653 screened participants, we included 283 AQP4-IgG-seropositive patients with NMOSD and 72 ...
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    4. Reliability of Corneal, Epithelial, and Stromal Thickness Mapping for a 9-mm Zone Using Spectral-Domain Optical Coherence Tomography

      Reliability of Corneal, Epithelial, and Stromal Thickness Mapping for a 9-mm Zone Using Spectral-Domain Optical Coherence Tomography
      Purpose: To evaluate the reliability of spectral-domain optical coherence tomography (SD-OCT; RTVue XR; Optovue, Inc., Fremont, CA, USA) for thickness mapping of the entire cornea (CT), corneal epithelium (ET). and corneal stroma (ST) over a 9-mm zone in healthy eyes. We sought to develop reference values for different age groups and elucidate potential sex- and age-dependent characteristics of corneal sublayer pachymetry maps. Methods: Three consecutive SD-OCT scans were obtained in ...
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    5. Spectral domain optical coherence tomography-based retinochoroidal cystine crystal score: a window into infantile nephropathic cystinosis

      Spectral domain optical coherence tomography-based retinochoroidal cystine crystal score: a window into infantile nephropathic cystinosis
      PRCIS: Cystinosis is a lysosomal storage disease leading to an accumulation of cystine crystals in several organs. We aim to comprehensively describe chorioretinal cystine crystals via spectral domain optical coherence tomography (SD-OCT) and elaborate a new biomarker for systemic disease control. Background/aims: Cystinosis is a rare lysosomal storage disease leading to an accumulation of cystine crystals in several organs. This study aims to describe the deposition of retinochoroidal crystals ...
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    6. Line-field confocal optical coherence tomography for the in-vivo real-time diagnosis of different stages of keratinocyte skin cancer: a preliminary study

      Line-field confocal optical coherence tomography for the in-vivo real-time diagnosis of different stages of keratinocyte skin cancer: a preliminary study
      Background: The treatment of keratinocyte cancers (KC) strictly depends on their differentiation and invasiveness. Non-invasive diagnostic techniques can support the diagnosis in real-time, avoiding unnecessary biopsies. This study aimed to preliminarily define main imaging criteria and histological correlations of actinic keratosis (AK), Bowen's disease (BD) and squamous cell carcinoma (SCC) using the novel device line-field confocal optical coherence tomography (LC-OCT). Methods: Dermoscopy and LC-OCT images of 73 histopathologically confirmed ...
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    7. Changes of Neuroretinal Rim and Retinal Nerve Fiber Layer Thickness Assessed by Optical Coherence Tomography After Filtration Surgery in Glaucomatous Eyes

      Changes of Neuroretinal Rim and Retinal Nerve Fiber Layer Thickness Assessed by Optical Coherence Tomography After Filtration Surgery in Glaucomatous Eyes
      ...ery (trabeculectomy or deep sclerectomy with MMC, respectively) at the Department of Ophthalmology of Munich, Ludwig-Maximilians University in 2017, carried out by one single surgeon. Inclusion criteria were medically un...
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    8. The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies

      The APOSTEL 2.0 Recommendations for Reporting Quantitative Optical Coherence Tomography Studies
      Objective: To update the consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results, thus revising the previously published Advised Protocol for OCT Study Terminology and Elements (APOSTEL) recommendations. Methods: To identify studies reporting quantitative OCT results, we performed a PubMed search for the terms "quantitative" and "optical coherence tomography" from 2015 to 2017. Corresponding authors of the identified publications were invited to provide feedback on the initial ...
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    9. Optical coherence tomography for patch test grading: A prospective study on its use for noninvasive diagnosis of allergic contact dermatitis

      Optical coherence tomography for patch test grading: A prospective study on its use for noninvasive diagnosis of allergic contact dermatitis
      Background The diagnosis of allergic contact dermatitis should be confirmed by skin patch tests. Distinguishing between irritant and allergic reactions is sometimes difficult. Objectives To analyse the in vivo morphological changes in patch test reactions compared to healthy skin, and to detect subclinical changes in doubtful reactions using optical coherence tomography (OCT). To develop an OCT‐based algorithm to support patch‐test grading. Methods One hundred twenty‐nine skin patch ...
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    10. Use of intravascular optical coherence tomography or intravascular ultrasound to guide stent implantation. The choice is yours!

      Use of intravascular optical coherence tomography or intravascular ultrasound to guide stent implantation. The choice is yours!
      In the current issue of EuroIntervention, the one-year follow-up of the ILUMIEN III trial1 and the design and rationale of the ILUMIEN IV trial2 are presented. Both trials are part of a series of clinical studies designed to provide hypothesis-generating knowledge and hypothesis-confirming answers in a systematic way. The prospective, observational ILUMIEN I trial demonstrated that the anatomical vessel information, as provided by optical coherence tomography (OCT), impacts on the ...
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    11. Cardiac allograft vasculopathy: Differences of absolute and relative intimal hyperplasia in children versus adults in optical coherence tomography

      Cardiac allograft vasculopathy: Differences of absolute and relative intimal hyperplasia in children versus adults in optical coherence tomography
      Background Intracoronary imaging enables an early detection of intimal changes. To what extend the development of absolute and relative intimal hyperplasia in intracoronary imaging differs depending on age and post-transplant time is not known. Methods Aim of our retrospective study was to compare findings between 24 pediatric (cohort P) and 21 adult HTx patients (cohort A) using optical coherence tomography (OCT) at corresponding post-transplant intervals (5 years: P1 ( n = 11 ...
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    12. Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders

      Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders
      Purpose Optical coherence tomography (OCT) captures retinal damage in neuromyelitis optica spectrum disorders (NMOSD). Previous studies investigating OCT in NMOSD have been limited by the rareness and heterogeneity of the disease. The goal of this study was to establish an image repository platform, which will facilitate neuroimaging studies in NMOSD. Here we summarise the profile of the Collaborative OCT in NMOSD repository as the initial effort in establishing this platform ...
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    13. Establishing an objective biomarker for corneal cystinosis using a threshold‐based Spectral domain optical coherence tomography imaging algorithm

      Establishing an objective biomarker for corneal cystinosis using a threshold‐based Spectral domain optical coherence tomography imaging algorithm
      Purpose The purpose of the present study was to establish a semi‐automated threshold‐based image segmentation algorithm to detect and objectively quantify corneal cystine crystal deposition in ocular cystinosis with anterior segment optical coherence tomography (AS‐OCT). Methods This prospective, observational, comparative study included 88 eyes of 45 patients from the German Cystinosis Registry Study as well as 68 eyes of 35 healthy control subjects. All eyes were imaged ...
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    14. Corneal optical density in Fuchs endothelial dystrophy determined by anterior segment optical coherence tomography

      Corneal optical density in Fuchs endothelial dystrophy determined by anterior segment optical coherence tomography
      Purpose: In this study, we propose a method to grade corneal stromal opacity using optical density measurements by anterior segment optical coherence tomography (AS-OCT) and validate the approach in Fuchs endothelial corneal dystrophy (FECD). Methods: A retrospective analysis of human corneal OCT scans was performed on 48 eyes of 32 patients with FECD and 33 control eyes of 21 patients using the Carl Zeiss Cirrus HD-OCT 5000. In addition, corneal ...
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    15. In vivo Imaging of Sarcoptes scabiei infestation using Line‐field Confocal Optical Coherence Tomography

      In vivo Imaging of Sarcoptes scabiei infestation using Line‐field Confocal Optical Coherence Tomography
      Scabies remains a worldwide spread disease of considerable health and economic burden with repeated outbreaks in community settings.(1) Scabies agent is the ectoparasite Sarcoptes scabiei var. hominis ; this invisible mite causes a progressive rash, which can be misdiagnosed with eczema or pruritus sine materia . Diagnosis is based on characteristic clinical features (intense nightly itch, inflammatory excoriated papules in typical sites) and history of contact to infected patients.
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  2. About Ludwig Maximilian University of Munich

    Ludwig Maximilian University of Munich (Ludwig-Maximilians-Universität München), also known as LMU, is a university in Munich and, with more than 44,000 students, is the second-largest university in Germany. The majority of foreign exchanges at the University of Munich are with European universities. The main building is situated in Ludwigstrasse. The university's main campus is served by the Munich U-Bahn's Universität station.