1. Ludwig Maximilian University of Munich

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    1. Mentioned In 160 Articles

    2. Use of intravascular optical coherence tomography or intravascular ultrasound to guide stent implantation. The choice is yours!

      Use of intravascular optical coherence tomography or intravascular ultrasound to guide stent implantation. The choice is yours!
      In the current issue of EuroIntervention, the one-year follow-up of the ILUMIEN III trial1 and the design and rationale of the ILUMIEN IV trial2 are presented. Both trials are part of a series of clinical studies designed to provide hypothesis-generating knowledge and hypothesis-confirming answers in a systematic way. The prospective, observational ILUMIEN I trial demonstrated that the anatomical vessel information, as provided by optical coherence tomography (OCT), impacts on the ...
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    3. Cardiac allograft vasculopathy: Differences of absolute and relative intimal hyperplasia in children versus adults in optical coherence tomography

      Cardiac allograft vasculopathy: Differences of absolute and relative intimal hyperplasia in children versus adults in optical coherence tomography
      Background Intracoronary imaging enables an early detection of intimal changes. To what extend the development of absolute and relative intimal hyperplasia in intracoronary imaging differs depending on age and post-transplant time is not known. Methods Aim of our retrospective study was to compare findings between 24 pediatric (cohort P) and 21 adult HTx patients (cohort A) using optical coherence tomography (OCT) at corresponding post-transplant intervals (5 years: P1 ( n = 11 ...
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    4. Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders

      Cohort profile: a collaborative multicentre study of retinal optical coherence tomography in 539 patients with neuromyelitis optica spectrum disorders
      Purpose Optical coherence tomography (OCT) captures retinal damage in neuromyelitis optica spectrum disorders (NMOSD). Previous studies investigating OCT in NMOSD have been limited by the rareness and heterogeneity of the disease. The goal of this study was to establish an image repository platform, which will facilitate neuroimaging studies in NMOSD. Here we summarise the profile of the Collaborative OCT in NMOSD repository as the initial effort in establishing this platform ...
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    5. Establishing an objective biomarker for corneal cystinosis using a threshold‐based Spectral domain optical coherence tomography imaging algorithm

      Establishing an objective biomarker for corneal cystinosis using a threshold‐based Spectral domain optical coherence tomography imaging algorithm
      Purpose The purpose of the present study was to establish a semi‐automated threshold‐based image segmentation algorithm to detect and objectively quantify corneal cystine crystal deposition in ocular cystinosis with anterior segment optical coherence tomography (AS‐OCT). Methods This prospective, observational, comparative study included 88 eyes of 45 patients from the German Cystinosis Registry Study as well as 68 eyes of 35 healthy control subjects. All eyes were imaged ...
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    6. Corneal optical density in Fuchs endothelial dystrophy determined by anterior segment optical coherence tomography

      Corneal optical density in Fuchs endothelial dystrophy determined by anterior segment optical coherence tomography
      Purpose: In this study, we propose a method to grade corneal stromal opacity using optical density measurements by anterior segment optical coherence tomography (AS-OCT) and validate the approach in Fuchs endothelial corneal dystrophy (FECD). Methods: A retrospective analysis of human corneal OCT scans was performed on 48 eyes of 32 patients with FECD and 33 control eyes of 21 patients using the Carl Zeiss Cirrus HD-OCT 5000. In addition, corneal ...
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    7. In vivo Imaging of Sarcoptes scabiei infestation using Line‐field Confocal Optical Coherence Tomography

      In vivo Imaging of Sarcoptes scabiei infestation using Line‐field Confocal Optical Coherence Tomography
      Scabies remains a worldwide spread disease of considerable health and economic burden with repeated outbreaks in community settings.(1) Scabies agent is the ectoparasite Sarcoptes scabiei var. hominis ; this invisible mite causes a progressive rash, which can be misdiagnosed with eczema or pruritus sine materia . Diagnosis is based on characteristic clinical features (intense nightly itch, inflammatory excoriated papules in typical sites) and history of contact to infected patients.
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    8. OCT angiography in optic disc drusen: comparison with structural and functional parameters

      OCT angiography in optic disc drusen: comparison with structural and functional parameters
      Background Optic disc drusen (ODD) can cause retinal nerve fibre layer (RNFL) defects with progressive visual field (VF) loss. Microvascular changes are discussed as a cause. We measured the vessel density (VD) of the optic disc in ODD using optical coherence tomography angiography and compared it with a normal population. Another intent was to determine the sensitivity and correlations in comparison with functional (VF) and structural parameters (RNFL, minimum rim ...
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    9. Effects of Flavanol-Rich Dark Chocolate on Visual Function and Retinal Perfusion Measured With Optical Coherence Tomography Angiography

      Effects of Flavanol-Rich Dark Chocolate on Visual Function and Retinal Perfusion Measured With Optical Coherence Tomography Angiography
      Importance A recently reported randomized clinical trial suggested beneficial effects of vasodilating flavanols in dark chocolate on visual function without objective quantification of retinal perfusion. Objective To assess the effects of dark chocolate flavanols on subjective visual function and retinal perfusion objectively quantified on optical coherence tomography (OCT) angiography. Design, Setting, and Participants This randomized, masked double-blind crossover clinical trial analyzed 22 healthy participants at the Department of Ophthalmology, Ludwig ...
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    10. Nickel contact dermatitis evaluated by means of optical coherence tomography: first impressions

      Nickel contact dermatitis evaluated by means of optical coherence tomography: first impressions
      Nickel contact allergy, a major health problem in the general population, is usually diagnosed through appropriate clinical history and patch testing.(1, 2) Patch‐test results are not fully objectivable and are influenced by the observer's experience.(3) Moreover, not every individual with nickel‐sensitization develops a clinically visible contact allergy. We hypothesized that non‐invasive diagnostic techniques such as optical coherence tomography (OCT) could provide further details in ...
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    11. Vitrectomy for diabetic macular edema: optical coherence tomography criteria and pathology of the vitreomacular interface

      Vitrectomy for diabetic macular edema: optical coherence tomography criteria and pathology of the vitreomacular interface
      Purpose To correlate spectral-domain optical coherence tomography (SD-OCT) criteria and clinical data with pathology of the vitreomacular interface (VMI) in eyes with diabetic macular edema (DME). Design Retrospective cross-sectional study and laboratory investigation. Methods We included specimens of 27 eyes of 26 patients with center-involved DME that underwent vitrectomy with peeling of the internal limiting membrane (ILM). Selection of specimens was consecutive and in retrospect using our register of the ...
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    12. Neoatherosclerosis in Patients With Coronary Stent Thrombosis: Findings From Optical Coherence Tomography Imaging (A Report of the PRESTIGE Consortium)

      Neoatherosclerosis in Patients With Coronary Stent Thrombosis: Findings From Optical Coherence Tomography Imaging (A Report of the PRESTIGE Consortium)
      Objectives The purpose of this study was to assess neoatherosclerosis in a registry of prospectively enrolled patients presenting with stent thrombosis using optical coherence tomography . Background In-stent neoatherosclerosis was recently identified as a novel disease manifestation of atherosclerosis after coronary stent implantation. Methods Angiography and intravascular optical coherence tomography were used to investigate etiologic factors of neoatherosclerosis in patients presenting with stent thrombosis 1 year after implantation (very late stent ...
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    13. The Relationship Between Blue-Fundus Autofluorescence and Optical Coherence Tomography in Eyes With Lamellar Macular Holes

      The Relationship Between Blue-Fundus Autofluorescence and Optical Coherence Tomography in Eyes With Lamellar Macular Holes
      Purpose : The purpose of this study was to evaluate the relationship between blue-fundus autofluorescence (B-FAF) and optical coherence tomography (OCT) in eyes with lamellar macular holes (LMHs). Methods : this was a multicenter, observational case series. Ninety-two eyes with LMH associated with the standard epiretinal membrane (ERM) or lamellar holeassociated epiretinal proliferation (LHEP) were evaluated. The eyes must also present an area of increased autofluorescence on B-FAF. Results : The ERM-alone group ...
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    14. Swept source OCT system and method with phase-locked detection

      Swept source OCT system and method with phase-locked detection
      A swept source OCT system and related method are disclosed. The system comprises a control device for operating a tunable light source in response to an electronic sweep control signal such that the tunable light source carries out wave length sweeps with a repetition rate f.sub.sweep, which depends on the frequency of the sweep control signal. The system further comprises a detection device for the time-resolved detection of ...
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    15. Impact of Preinjection Spectral Domain Optical Coherence Tomography Findings in the Use of Intravitreal Ocriplasmin in a Clinical Setting

      Impact of Preinjection Spectral Domain Optical Coherence Tomography Findings in the Use of Intravitreal Ocriplasmin in a Clinical Setting
      To investigate the impact of spectral domain optical coherence tomography (SD-OCT) morphological predictive markers on visual acuity and outcome using ocriplasmin for macular hole and vitreomacular traction syndrome. Methods: A series of 40 patients in a retrospective study received intravitreal ocriplasmin. The primary endpoint was defined as morphological resolution of vitreomacular traction or closure of a macular hole. We analyzed the impact of pre- and postinjection SD-OCT findings on the ...
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  2. About Ludwig Maximilian University of Munich

    Ludwig Maximilian University of Munich (Ludwig-Maximilians-Universität München), also known as LMU, is a university in Munich and, with more than 44,000 students, is the second-largest university in Germany. The majority of foreign exchanges at the University of Munich are with European universities. The main building is situated in Ludwigstrasse. The university's main campus is served by the Munich U-Bahn's Universität station.