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1. Mentioned In 38 Articles
2. Methods of reducing motion artifacts for optical coherence tomography angiography
  
  Explore uspto.gov Sep 12 2017 Ophthalmology , Patents
  
  A method for reducing motion artifacts in optical coherence tomography (OCT) angiography images is disclosed. The method is applied to the intensity or complex OCT data prior to applying the motion contrast analysis and involves determining sub-pixel level shifts between at least two B-scans repeated approximately at the same location and applying the sub-pixel level shifts to the B-scans to be able to correct for motion and accurately determine motion ...
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  Mentions: Utkarsh Sharma University of Washington Carl Zeiss Meditec
3. Acquistion and analysis techniques for improved outcomes in optical coherence tomography angiography
  
  Explore uspto.gov Jul 11 2017 Ophthalmology , Patents
  
  Abstract Methods for improved acquisition and processing of optical coherence tomography (OCT) angiography data are presented. One embodiment involves improving the acquisition of the data by evaluating the quality of different portions of the data to identify sections having non-uniform acquisition parameters or non-uniformities due to opacities in the eye such as floaters. The identified sections can then be brought to the attention of the user or automatically reacquired. In ...
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  Mentions: Utkarsh Sharma Carl Zeiss Meditec Lin An
4. Comparison Between Spectral-Domain and Swept-Source Optical Coherence Tomography Angiographic Imaging of Choroidal Neovascularization
  
  Explore IOVS Journal Mar 10 2017 Ophthalmology
  
  Purpose : The purpose of this study was to compare imaging of choroidal neovascularization (CNV) using swept-source (SS) and spectral-domain (SD) optical coherence tomography angiography (OCTA). Methods : Optical coherence tomography angiography was performed using a 100-kHz SS-OCT instrument and a 68-kHz SD-OCTA instrument (Carl Zeiss Meditec, Inc.). Both 3 3- and 6 6-mm 2 scans were obtained on both instruments. The 3 3-mm 2 SS-OCTA scans consisted of 300 A-scans per ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld Universidade Federal de São Paulo
5. Projection Artifact Removal Improves Visualization and Quantitation of Macular Neovascularization Imaged by Optical Coherence Tomography Angiography
  
  Explore ScienceDirect Nov 9 2016 Ophthalmology
  
  Purpose To visualize and quantify the size and vessel density of macular neovascularization (MNV) using optical coherence tomography angiography (OCTA) with a projection artifact removal algorithm. Design Multicenter, observational study. Participants Subjects with MNV in 1 eye. Methods Patients were imaged using either a swept-source OCTA prototype system or a spectral-domain OCTA prototype system. The optical microangiography (OMAG) algorithm was used to generate the OCTA images. Projection artifacts from the ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld University of Washington
6. Optical Coherence Tomography Angiography of Asymptomatic Neovascularization in Intermediate Age-Related Macular Degeneration
  
  Explore Ophthalmology Feb 12 2016 Ophthalmology
  
  Purpose To determine whether angiography with swept-source (SS) optical coherence tomography (OCT) identifies subclinical type 1 neovascularization in asymptomatic eyes with intermediate age-related macular degeneration (iAMD). Design Prospective, observational, consecutive case series. Participants Patients with asymptomatic iAMD in one eye and neovascular age-related macular degeneration (AMD) in their fellow eye. Methods The patients underwent SS OCT angiography (OCTA), fluorescein angiography (FA), and indocyanine green angiography (ICGA), and the images from ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld University of Washington
7. SWEPT SOURCE OCT ANGIOGRAPHY OF NEOVASCULAR MACULAR TELANGIECTASIA TYPE 2
  
  Explore LWW Online Oct 14 2015 Ophthalmology
  
  Background/Purpose: To image subretinal neovascularization in proliferative macular telangiectasia Type 2 (MacTel2) using swept source optical coherence tomography based microangiography (OMAG). Methods: Patients with macular telangiectasia Type 2 were enrolled in a prospective, observational study known as the MacTel Project and evaluated using a high-speed 1,050 nm swept-source OCT prototype system. The OMAG algorithm generated en face flow images from three retinal layers, and the region bounded by ...
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  Mentions: Philip J. Rosenfeld Utkarsh Sharma University of Washington
8. Noninvasive Visualization and Analysis of the Human Parafoveal Capillary Network Using Swept Source OCT Optical Microangiography
  
  Explore IOVS Journal Jun 26 2015 Ophthalmology
  
  Purpose. We characterized the foveal avascular zone (FAZ) and the parafoveal capillary network in healthy subjects using swept source OCT optical microangiography (OMAG). Methods. We acquired OMAG images of the macula of 19 eyes (13 healthy individuals) using a prototype swept source laser OCT. En face images of the retinal vasculature were generated for superficial and deep inner retinal layers (SRL/DRL) in regions of interest 250 (ROI-250) and 500 ...
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  Mentions: Carl Zeiss Meditec Srinivas R. Sadda UCLA
9. Wide-field imaging of retinal vasculature using optical coherence tomography-based microangiography provided by motion tracking.
  
  Explore SPIE | Journal Jun 24 2015 Ophthalmology
  
  Optical coherence tomography (OCT)-based optical microangiography (OMAG) is a high-resolution, noninvasive imaging technique capable of providing three-dimensionalin vivoblood flow visualization within microcirculatory tissue beds in the eye. Although the technique has demonstrated early clinical utility by imaging diseased eyes, its limited field of view (FOV) and the sensitivity to eye motion remain the two biggest challenges for the widespread clinical use of the technology. Here, we report the results ...
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  Mentions: Utkarsh Sharma University of Washington Carl Zeiss Meditec
10. Imaging Areas of Retinal Nonperfusion in Ischemic Branch Retinal Vein Occlusion With Swept-Source OCT Microangiography
  
  Explore Healio.com Feb 24 2015 Ophthalmology
  
  The authors present the case of a patient with a history of ischemic branch vein occlusion and multimodal imaging of the retinal vasculature by fluorescein angiography (FA) and ultrahigh-speed swept-source optical coherence tomography (SS-OCT) microangiography (SS-OCT laser prototype; 1,050 nm, 100,000 A-scans/second). Multiple images across the macula were acquired (3 3 mm cubes in clusters of four repeated B-scans). En face images of the vasculature were generated ...
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  Mentions: Optovue University of Southern California Carl Zeiss Meditec
11. Swept-Source OCT Angiography of Macular Telangiectasia Type 2
  
  Explore Healio.com Oct 9 2014 Ophthalmology
  
  BACKGROUND AND OBJECTIVE: To evaluate the central macular microvascular network in patients with macular telangiectasia type 2 (MacTel2) using optical coherence tomography (OCT)-based microangiography (OMAG). PATIENTS AND METHODS: Prospective, observational study of patients with MacTel2 evaluated using a swept-source OCT (SS-OCT) prototype. OMAG was performed using a 3 mm 3 mm central foveal raster scan. The algorithm segmented the retina into three layers. Microvascular distribution was depicted as en ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld George Washington University
12. Swept-Source OCT Angiography of the Retinal Vasculature Using Intensity Differentiation-based Optical Microangiography Algorithms
  
  Explore Healio.com Sep 23 2014 Ophthalmology
  
  To demonstrate the feasibility of using a 1,050-nm swept-source optical coherence tomography (SS-OCT) system to achieve noninvasive retinal vasculature imaging in human eyes. MATERIALS AND METHODS: Volumetric data sets were acquired using a 1-m SS-OCT prototype that operated at a 100-kHz A-line rate. A scanning protocol designed to allow for motion contrast processing, referred to as OCT angiography or optical microangiography (OMAG), was used to scan an approximately 3 ...
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  Mentions: Giovanni Gregori Philip J. Rosenfeld Utkarsh Sharma
13. Method and apparatus for quantitative imaging of blood perfusion in living tissue
  
  Explore uspto.gov Jun 10 2014 Patents
  
  Embodiments provide methods and systems for quantitative imaging of blood perfusion in living tissue. A method provides for obtaining an optical microangiography (OMAG) image of a sample, wherein the image has an OMAG background sample; digitally reconstructing a homogeneous ideal static background tissue; replacing the OMAG background sample with the digitally reconstructed homogeneous ideal static background tissue; correlating two or more neighboring A-lines with the digitally reconstructed homogeneous ideal static ...
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  Mentions: Oregon Health & Science University Ruikang K. Wang Lin An
14. Development of Spectral Domain Optical Coherence Tomography for in vivo Functional Imaging of Biological Tissues (Thesis)
  
  Explore digital.lib.washington.edu Jul 30 2013 Student Theses
  
  Optical coherence tomography is a rapidly developing optical imaging modality capable of noninvasively providing depth resolved information of biological tissue at micrometer scale. Since its first report in 1991, it has made tremendous progress leading to successful applications in a number of fields, such as ophthalmology, gastroenterology, dermatology, dentistry, dermatology, cardiology, etc. According to [1], there are more than 15, 000 OCT units that had been put into service in ...
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  Mentions: University of Washington FDA Lin An
15. Noninvasive imaging of pulsatile movements of the optic nerve head in normal human subjects using phase-sensitive spectral domain optical coherence tomography
  
  Explore opticsinfobase.org Apr 24 2013 Ophthalmology
  
  ...simultaneously measured pulsatile blood flow in the central retinal artery. © 2013 Optical Society of America Lin An, Jennifer Chao, Murray Johnstone, and Ruikang K. Wang, "Noninvasive imaging of pulsatile movements of t...
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  Mentions: University of Washington Ruikang K. Wang Lin An
16. High-resolution 1050 nm spectral domain retinal optical coherence tomography at 120 kHz A-scan rate with 6.1 mm imaging depth
  
  Explore opticsinfobase.org Jan 22 2013 Ophthalmology
  
  We report a newly developed high speed 1050nm spectral domain optical coherence tomography (SD-OCT) system for imaging posterior segment of human eye. The system is capable of an axial resolution at ~10 m in air, an imaging depth of 6.1 mm in air, a system sensitivity fall-off at ~6 dB/3mm and an imaging speed of 120,000 A-scans per second. We experimentally demonstrate the systems capability to perform ...
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  Mentions: University of Washington Douglas S. Malchow UTC Aerospace Systems
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