Articles that mention Laura J. Balcer -Optical Coherence Tomography News

Laura J. Balcer

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1. Mentioned In 44 Articles
2. Optimal intereye difference thresholds by optical coherence tomography in multiple sclerosis: An international study
  
  Explore Wiley Online Library 20 hours, 37 min ago Neurology , Ophthalmology
  
  Objective To determine the optimal thresholds for intereye differences in retinal nerve fiber and ganglion cell + inner plexiform layer thicknesses for identifying unilateral optic nerve lesions in multiple sclerosis. Current international diagnostic criteria for multiple sclerosis do not include the optic nerve as a lesion site despite frequent involvement. Optical coherence tomography detects retinal thinning associated with optic nerve lesions. Methods In this multicenter international study at 11 sites, optical ...
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  Mentions: Peter A. Calabresi Johns Hopkins University Laura J. Balcer
3. Optimal Inter‐Eye Difference Thresholds by OCT in MS: An International Study
  
  Explore Wiley Online Library Mar 14 2019 Neurology , Ophthalmology
  
  Objective To determine the optimal thresholds for inter‐eye differences in retinal nerve fiber and ganglion cell+inner plexiform layer thicknesses for identifying unilateral optic nerve lesions in multiple sclerosis. Background Current international diagnostic criteria for multiple sclerosis do not include the optic nerve as a lesion site despite frequent involvement. Optical coherence tomography detects retinal thinning associated with optic nerve lesions. Methods In this multi‐center international study at ...
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  Mentions: Peter A. Calabresi Johns Hopkins University Laura J. Balcer
4. The International Multiple Sclerosis Visual System Consortium: Advancing Visual System Research in Multiple Sclerosis
  
  Explore LWW Online Nov 13 2018 Neurology , Ophthalmology
  
  Background: The International Multiple Sclerosis Visual System Consortium (IMSVISUAL) was formed in November 2014 with the primary goal of improving research, care, and education regarding the role of the visual system in multiple sclerosis (MS) and related disorders. Methods: In this review, we describe the formation, goals, activities, and structure of IMSVISUAL, as well as the relationship of IMSVISUAL with the Americas Committee for Treatment and Research in MS (ACTRIMS ...
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  Mentions: Peter A. Calabresi Johns Hopkins University University College London
5. Evolution of Visual Outcomes in Clinical Trials for Multiple Sclerosis Disease-Modifying Therapies
  
  Explore insights.ovid.com May 15 2018 Neurology , Ophthalmology
  
  rom the Section Editor: In March 2018, the Journal of Neuro-Ophthalmology (JNO) launched its inaugural Disease of the Year section, featuring multiple sclerosis (MS). Beginning from a Bench perspective, Meltzner and colleagues presented an elegant overview of the pathogenic mechanisms believed to underpin central nervous system (CNS) injury in MS. To complement these efforts, Backner and Levin highlighted how the afferent visual pathway, as a putative model of CNS inflammation ...
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  Mentions: Johns Hopkins University Laura J. Balcer FDA
6. Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study
  
  Explore TheLancet.com Dec 12 2017 Neurology , Ophthalmology
  
  Background Most patients with multiple sclerosis without previous optic neuritis have thinner retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre layer (pRNFL) thickness and macular volume in eyes with no history of optic neuritis as a biomarker of disability worsening in a cohort of patients with multiple sclerosis who had at least one eye without optic neuritis available. Methods In this multicentre, cohort study ...
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  Mentions: Peter A. Calabresi Johns Hopkins University Laura J. Balcer
7. Optical coherence tomography in an optic tract lesion, Retinal nerve fiber layer changes
  
  Explore Neurology Nov 7 2016 Neurology , Ophthalmology
  
  A 49-year-old woman, status post temporal lobe resection, reported a hemianopia. Examination revealed a right afferent pupillary defect, horizontal bow-tie atrophy OD (temporal and nasal), and temporal atrophy OS. Optical coherence tomography showed a bow-tie pattern OD and predominant superior and inferior nerve fiber layer loss OS (figure 1; figure e-1 at Neurology.org ). The pattern OD is due to the combination of papillomacular bundle and nasal RNFL loss. The ...
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  Mentions: Johns Hopkins University Laura J. Balcer
8. Evaluation of the conjuntival blebs using spectral domain optical coherence tomography after glaucoma surgery
  
  Explore Home Jul 23 2016 Ophthalmology
  
  Objective to investigate whether optical coherence tomography (OCT) could demonstrate axonal loss through thinning of the retinal nerve fiber layer (RNFL) in multiple sclerosis (MS) patients. Furthermore, the degree of RNFL loss was compared in the different MS subgroups (with or without optic neuritis, affected or fellow eye, single episode or recurrent optic neuritis, relapsing remitting or progressive MS). RNFL thinning was also determined in MS patients who had serial ...
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  Mentions: Laura J. Balcer Fiona E. Costello
9. The APOSTEL recommendations for reporting quantitative optical coherence tomography studies
  
  Explore Neurology May 25 2016 Neurology , Ophthalmology
  
  Objective: To develop consensus recommendations for reporting of quantitative optical coherence tomography (OCT) study results. Methods: A panel of experienced OCT researchers (including 11 neurologists, 2 ophthalmologists, and 2 neuroscientists) discussed requirements for performing and reporting quantitative analyses of retinal morphology and developed a list of initial recommendations based on experience and previous studies. The list of recommendations was subsequently revised during several meetings of the coordinating group. Results: We ...
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  Mentions: Peter A. Calabresi Johns Hopkins University Joel S. Schuman
10. Optical Coherence Tomography in Neurologic Disease (Textbook)
  
  Explore Cambridge Books Online Mar 30 2016 Neurology , Ophthalmology , Textbooks
  
  Shortly after the invention of the first two-dimensional optical coherence tomography (OCT) scans by James Fujimoto and colleagues at the Massachusetts Institute of Technology in 1991, ophthalmologists recognized the extraordinary potential for OCT to facilitate quantitative assessment of the neuroretina. OCT rapidly became a commonplace tool in ophthalmologic practice to identify both inflammatory and degenerative conditions affecting the optic nerve and retina. The utility of OCT to detect and quantify ...
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  Mentions: Peter A. Calabresi Johns Hopkins University Massachusetts Institute of Technology
11. Retinal thickness measured with optical coherence tomography and risk of disability worsening in multiple sclerosis: a cohort study
  
  Explore TheLancet.com Mar 19 2016 Neurology , Ophthalmology
  
  Background Most patients with multiple sclerosis without previous optic neuritis have thinner retinal layers than healthy controls. We assessed the role of peripapillary retinal nerve fibre layer (pRNFL) thickness and macular volume in eyes with no history of optic neuritis as a biomarker of disability worsening in a cohort of patients with multiple sclerosis who had at least one eye without optic neuritis available. Methods In this multicentre, cohort study ...
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  Mentions: Peter A. Calabresi Johns Hopkins University University College London
12. Utility of optical coherence tomography in the evaluation of monocular visual loss related to retinal ischemia
  
  Explore Journal of Clinical Neuroscience Jan 15 2016 Neurology , Ophthalmology
  
  We report four patients with monocular visual loss for whom optical coherence tomography (OCT) was helpful in distinguishing the sequelae of retinal artery occlusion from those of primary optic neuropathy. Determinations of the peripapillary retinal nerve fiber layer (RNFL) thickness as well as macular retinal layer thicknesses and architecture were used. The major findings in our patients show that changes in the inner retinal layers (including ganglion cell and inner ...
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  Mentions: Laura J. Balcer
13. Leading Edge Collaboration in Eye-Related Research Earns Investigators at NYU Langone Medical Center, Johns Hopkins, and the UT Southwestern Medical Center the 2015 Barancik Prize for Innovation in MS Research
  
  Explore PR Newswire Oct 29 2015 Neurology , Ophthalmology
  
  The collaborative team of Drs. Laura Balcer , Peter Calabresi and Elliot Frohman have been selected as the winners of the 2015 Barancik Prize for Innovation in MS Research. This team of physician-scientists have worked together for almost 10 years to produce novel, ground-breaking and impactful research about the anatomy and biology of the retina and other structures of the eye in people with multiple sclerosis (MS). In their more than ...
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  Mentions: Peter A. Calabresi Laura J. Balcer Scheie Eye Institute
14. Optical Coherence Tomography for the Neurologist
  
  Explore Thieme Oct 8 2015 Neurology , Ophthalmology
  
  Optical coherence tomography (OCT) is a relatively new technology that is now routinely and very widely used by ophthalmologists for structural documentation of the optic nerve and retina. In neuro-ophthalmology and neurology, the value of OCT is ever expanding; its role in an increasing number of conditions is being reported in parallel with the advances of the technology. Currently, as a clinical tool, OCT is particularly useful for the structural ...
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  Mentions: Laura J. Balcer
15. Optical coherence tomography reflects brain atrophy in multiple sclerosis: A four-year study
  
  Explore Wiley Online Library Oct 2 2015 Neurology , Ophthalmology
  
  Objective The aim of this work was to determine whether atrophy of specific retinal layers and brain substructures are associated over time, in order to further validate the utility of optical coherence tomography (OCT) as an indicator of neuronal tissue damage in patients with multiple sclerosis (MS). Methods Cirrus high-definition OCT (including automated macular segmentation) was performed in 107 MS patients biannually (median follow-up: 46 months). Three-Tesla magnetic resonance imaging ...
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  Mentions: Peter A. Calabresi Johns Hopkins University Laura J. Balcer
16. Optical coherence tomography reflects brain atrophy in MS: A four year study
  
  Explore Wiley Online Library Jul 18 2015 Neurology , Ophthalmology
  
  Objective : To determine whether atrophy of specific retinal layers and brain substructures are associated over time, in order to further validate the utility of optical coherence tomography (OCT) as an indicator of neuronal tissue damage in patients with multiple sclerosis (MS). Methods : Cirrus high definition OCT (including automated macular segmentation) was performed in 107 MS patients biannually (median follow-up: 46-months). Three-tesla magnetic resonance imaging brain scans (including brain-substructure volumetrics) were ...
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  Mentions: Peter A. Calabresi Johns Hopkins University Laura J. Balcer
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