1. Lars Thrane

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    1. Mentioned In 28 Articles

    2. Complex regression Doppler optical coherence tomography

      Complex regression Doppler optical coherence tomography
      We introduce a new method to measure Doppler shifts more accurately and extend the dynamic range of Doppler optical coherence tomography (OCT). The two-point estimate of the conventional Doppler method is replaced with a regression that is applied to high-density B-scans in polar coordinates. We built a high-speed OCT system using a 1.68-MHz Fourier domain mode locked laser to acquire high-density B-scans (16,000 A-lines) at high enough frame ...
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    3. Complex decorrelation averaging in optical coherence tomography: a way to reduce the effect of multiple scattering and improve image contrast in a dynamic scattering medium

      Complex decorrelation averaging in optical coherence tomography: a way to reduce the effect of multiple scattering and improve image contrast in a dynamic scattering medium
      We demonstrate that complex decorrelation averaging can reduce the effect of multiple scattering and improve optical coherence tomography (OCT) imaging contrast. Complex decorrelation averaging calculates the product of an A-scan and the complex conjugate of a subsequent A-scan. The resultant signal is the product of the amplitudes and the phase difference. All these resulting complex signals at a particular location are then averaged. We take advantage of the fact that ...
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    4. Optical tissue clearing improves usability of optical coherence tomography (OCT) for high-throughput analysis of the internal structure and 3D morphology of small biological objects such as vertebrate embryos

      Optical tissue clearing improves usability of optical coherence tomography (OCT) for high-throughput analysis of the internal structure and 3D morphology of small biological objects such as vertebrate embryos
      ... analysis of the internal structure and 3D morphology of small biological objects such as vertebrate embryos Lars Thrane ; Thomas M. Jørgensen ; Jörg Männer; Optical tissue clearing improves usability of optical coheren...
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    5. Feature Of The Week 12/4/11: Technical University of Denmark Demonstrates First OCT Imaging of Polymer Solar Cell Modules

      Feature Of The Week 12/4/11: Technical University of Denmark Demonstrates First OCT Imaging of Polymer Solar Cell Modules
      ...s control by real-time adjustment to the production process.For more information see recent Article. Courtesy Lars Thrane from DTU Fotonik, Department of Photonics Engineering at the Technical University of Denmark (DTU)...
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    6. Application of optical coherence tomography (OCT) as a 3-dimensional imaging technique for roll-to-roll coated polymer solar cells

      Application of optical coherence tomography (OCT) as a 3-dimensional imaging technique for roll-to-roll coated polymer solar cells
      ...l coherence tomography (OCT) as a 3-dimensional imaging technique for roll-to-roll coated polymer solar cells Lars Thrane^a, Thomas M. Jørgensen^a, Mikkel Jørgensen^b, Frederik C. Krebs^b^, Corresponding Author Contact...
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    7. Rotationally acquired four-dimensional optical coherence tomography of embryonic chick hearts using retrospective gating on the common central A-scan

      Rotationally acquired four-dimensional optical coherence tomography of embryonic chick hearts using retrospective gating on the common central A-scan
      ... heart generated from a 4D OCT data set using rotational image acquisition. Christoph M. Happel, Jan Thommes, Lars Thrane, Jörg Männer, Tobias Ortmaier, Bodo Heimann and Talat Mesud Yelbuz, "Rotationally acquired four-di...
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    8. Integration of an Optical Coherence Tomography (OCT) System into an Examination Incubator to facilitate in vivo Imaging of Cardiovascular Development in higher vertebrate Embryos under stable physiological Conditions

      Integration of an Optical Coherence Tomography (OCT) System into an Examination Incubator to facilitate in vivo Imaging of Cardiovascular Development in higher vertebrate Embryos under stable physiological Conditions
      ...rticle. To view references and further reading you must purchase this article. Christoph M. Happel^a^, ^1, Lars Thrane^b^, ^1, Jan Thommes^c, Jörg Männer^d and T. Mesud Yelbuz^a^, ^Corresponding Author Con...
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    9. How histological features of basal cell carcinomas influence image quality in optical coherence tomography

      How histological features of basal cell carcinomas influence image quality in optical coherence tomography
      Optical coherence tomography (OCT) has the potential to diagnose and measure the depth of nonmelanoma skin cancer (NMSC) in skin, but some lesions appear blurred in OCT images. The aim of this study is to identify histological characteristics of basal cell carcinomas (BCC) that correlate with good quality OCT images of the same lesions. A total of 34 patients with BCC were OCT scanned. The influence of histology parameters (e ...
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    10. Open Post Doc/Research Assistant position: Swept-source optical coherence tomography system for ophthalmic use at Technical University of Denmark

      Open Post Doc/Research Assistant position: Swept-source optical coherence tomography system for ophthalmic use at Technical University of Denmark
      Optical coherence tomography (OCT) is an emerging imaging technology that enables high-resolution, cross-sectional imaging in biological tissues. OCT has been especially powerful for ophthalmic imaging, where it can provide images of retinal pathology with unprecedented resolutions. We seek a Post Doc/Research Assistant to finalize a project on the development of a 1050nm swept-source OCT system for ophthalmic use. The project is part of an existing collaboration with the major ...
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    11. In vivo imaging of the cyclic changes in cross-sectional shape of the ventricular segment of pulsating embryonic chick hearts at stages 14 to 17: A contribution to the understanding of the ontogenesis of cardiac pumping function

      The cardiac cycle-related deformations of tubular embryonic hearts were traditionally described as concentric narrowing and widening of a tube of circular cross-section. Using optical coherence tomography (OCT), we have recently shown that, during the cardiac cycle, only the myocardial tube undergoes concentric narrowing and widening while the endocardial tube undergoes eccentric narrowing and widening, having an elliptic cross-section at end-diastole and a slit-shaped cross-section at end-systole. Due to technical limitations ...
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    12. Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity

      Optical coherence tomography imaging of psoriasis vulgaris: correlation with histology and disease severity
      Epidermal thickness (ET) has been suggested as a surrogate measure of psoriasis severity. Optical coherence tomography (OCT) is a recent imaging technology that provides real-time skin images to a depth of 1.8 mm with a micrometre resolution. OCT may provide an accurate in vivo measure of ET. It is, therefore, speculated that OCT may be used in the assessment of psoriasis vulgaris. A total of 23 patients with psoriasis ...
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    13. Optical Coherence Tomography for Imaging of Skin and Skin Diseases

      Optical coherence tomography (OCT) is an emerging imaging technology based on light reflection. It provides real-time images with up to 2-mm penetration into the skin and a resolution of approximately 10 μm. It is routinely used in ophthalmology. The normal skin and its appendages have been studied, as have many diseases. The method can provide accurate measures of epidermal and nail changes in normal tissue. Skin cancer and other tumors ...
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  2. About Lars Thrane

    Lars Thrane

    Lars Thrane is a Research Associate in the Jenkins Lab at Case Western Reserve University. He has extensive experience with development of OCT imaging systems, development and application of OCT in especially developmental biology, dermatology, and non-destructive testing (NDT), theoretical OCT modeling including multiple light scattering effects, and extraction of optical scattering properties from OCT images.