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2. Predictors for layered coronary plaques: an optical coherence tomography study
  
  Explore Home - Springer Apr 24 2020 Cardiology
  
  Healed coronary plaques, morphologically characterized by a layered pattern, are signatures of previous plaque disruption and healing. Recent optical coherence tomography (OCT) studies showed that layered plaque is associated with vascular vulnerability. However, factors associated with layered plaques have not been studied. The aim of this study was to investigate predictors for layered plaque at the culprit plaques and at non-culprit plaques. Patients with coronary artery disease who underwent pre-intervention ...
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  Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University
3. Comprehensive In Vivo Coronary Plaque Mapping: A 3-Vessel Optical Coherence Tomography Study
  
  Explore ScienceDirect Mar 19 2020 Cardiology
  
  Background Previous pathology studies demonstrated that thin-cap fibroatheroma (TCFA) is localized in specific segments of the epicardial coronary arteries. A detailed description of in vivo coronary plaques of various phenotypes has not been reported. Objectives We performed a comprehensive analysis on the distribution of coronary plaques with different phenotypes from our 3-vessel optical coherence tomography (OCT) database. Methods OCT images of all 3 coronary arteries in 131 patients were analyzed ...
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  Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University
4. Comparison of post‐stent optical coherence tomography findings among three subtypes of calcified culprit plaques in patients with acute coronary syndrome
  
  Explore Wiley Online Library Mar 17 2020 Cardiology
  
  Objectives To compare the postprocedural optical coherence tomography (OCT) findings and in‐hospital outcomes among the three subtypes of calcified plaques: eruptive calcified nodules, superficial calcific sheet, and calcified protrusion. Background Recently, three subtypes of calcified culprit plaques were reported in patients with acute coronary syndrome (ACS). How these subtypes respond to stenting is unknown. Methods ACS patients with calcified plaque at the culprit lesion were selected from our database ...
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  Mentions: Massachusetts General Hospital Ik-Kyung Jang Masamichi Takano
5. Early versus delayed treatment with ticagrelor on residual thrombus after percutaneous coronary intervention in patients presenting with non-ST-elevation acute coronary syndrome: an optical coherence tomography study
  
  Explore LWW Online Jan 31 2020 Cardiology
  
  Ticagrelor, a P2Y12 antagonist, is well known for its rapid, high-potent inhibition of platelet aggregation by pharmacokinetic studies [ 1 ]. In the PLATO study, ticagrelor, compared to clopidogrel, reduced the incidence of myocardial infarction, stroke, cardiovascular death and definite stent thrombosis, during 12-month follow-up in patients with acute coronary syndrome (ACS) undergoing percutaneous coronary intervention (PCI) [ 2 , 3 ]. To date, the effect of early ticagrelor administration versus treatment at the time ...
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  Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University
6. Comparison of Anterior Segment Measurements between Scheimpflug Camera and New Module of Optical Coherence Tomography
  
  Explore KoreaMed Synapse Jul 21 2018 Ophthalmology
  
  Purpose We compared the anterior segment measurements using a Scheimpflug camera (Pentacam [Oculus Inc., Wetzlar, Germany]) and a new anterior segment module of optical coherence tomography (Cirrus HD-OCT 5000 [Carl Zeiss Meditec, Dublin, CA, USA]). Methods Anterior segment measurements were evaluated in 47 eyes of 26 patients who visited for the purpose of cataract surgery. Measurements of the central corneal thickness (CCT), anterior chamber depth (ACD), anterior chamber angle (ACA ...
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  Mentions: Carl Zeiss Meditec Kyung Hee University
7. Nonculprit Plaque Characteristics in Patients With Acute Coronary Syndrome Caused by Plaque Erosion vs Plaque Rupture A 3-Vessel Optical Coherence Tomography Study
  
  Explore The JAMA Network Feb 13 2018 Cardiology
  
  Importance Patients with culprit plaque rupture are known to have pancoronary plaque vulnerability. However, the characteristics of nonculprit plaques in patients with acute coronary syndromes caused by plaque erosion are unknown. Objective To investigate the nonculprit plaque phenotype in patients with acute coronary syndrome according to culprit plaque pathology (erosion vs rupture) by 3-vessel optical coherence tomography imaging. Design, Setting, and Participants In this observational cohort study, between August 2010 ...
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  Mentions: Brigham and Women’s Hospital Massachusetts General Hospital Ik-Kyung Jang
8. Optical coherence tomography angiography analysis of foveal microvascular changes and inner retinal layer thinning in patients with diabetes
  
  Explore BJO Online Dec 23 2017 Ophthalmology
  
  Aim To evaluate the correlation between inner retinal layer thinning and the foveal microvasculature in type 2 diabetes using optical coherence tomography angiography (OCTA). Methods A cross-sectional study involved 155 diabetic eyes. All patients were divided into two groups based on diabetic retinopathy (DR) grade: no DR (NDR, n=80) and mild-to-moderate non-proliferative DR (NPDR, n=75). Foveal avascular zone (FAZ) area, FAZ circularity index, FAZ perimeter, vessel density and ...
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  Mentions: Kyung Hee University
9. SYNTAX Score, and Pre- and Post-Stent Optical Coherence Tomography Findings in the Left Anterior Descending Coronary Artery in Patients with Stable Angina Pectoris
  
  Explore ScienceDirect Jul 5 2017 Cardiology
  
  SYNTAX score (SS) has been reported to be an independent predictor of future cardiac events including target lesion revascularization (TLR). The aim of this study was to assess the relationship between SS and plaque characteristics and post-stent vascular response using optical coherence tomography (OCT) in coronary artery tree and left anterior descending artery (LAD) in patients with stable angina. A total of 179 lesions among 165 patients, including 100 lesions ...
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  Mentions: University of Queensland Massachusetts General Hospital Ik-Kyung Jang
10. Clinical Significance of Lipid-Rich Plaque Detected by Optical Coherence Tomography : A 4-Year Follow-Up Study
  
  Explore ScienceDirect May 29 2017 Cardiology
  
  Background Lipid-rich plaque (LRP) is thought to be a precursor to cardiac events. However, its clinical significance in coronary arteries has never been systematically investigated. Objectives This study investigated the prevalence and clinical significance of LRP in the nonculprit region of the target vessel in patients undergoing percutaneous coronary intervention (PCI). Methods The study included 1,474 patients from 20 sites across 6 countries undergoing PCI, who had optical coherence ...
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  Mentions: University of Pittsburgh Massachusetts Institute of Technology James G. Fujimoto
11. CORRELATION BETWEEN PREOPERATIVE EN FACE OPTICAL COHERENCE TOMOGRAPHY OF PHOTORECEPTOR LAYER AND VISUAL PROGNOSIS AFTER MACULAR HOLE SURGERY
  
  Explore LWW Online May 28 2017 Ophthalmology
  
  Purpose: To investigate the correlation between preoperative en face spectral domain optical coherence tomography findings of the photoreceptor layer with restoration of foveal microstructure and visual acuity in repaired macular holes. Methods: Medical records of 106 patients with surgically closed macular holes were retrospectively reviewed. Preoperative OCT slabs of the external limiting membrane (ELM) and ellipsoid zone (EZ) were generated using embedded tools. All patients were classified into two groups ...
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  Mentions: Kyung Hee University
12. Characteristics of Earlier Versus Delayed Presentation of Very Late Drug‐Eluting Stent Thrombosis: An Optical Coherence Tomographic Study
  
  Explore jaha.ahajournals.org Apr 18 2017 Cardiology
  
  Background The pathophysiology underlying very late drug‐eluting stent ( DES ) thrombosis is not sufficiently understood. Using optical coherence tomography, we investigated characteristics of very late stent thrombosis ( VLST ) according to different onset times. Methods and Results A total of 98 patients from 10 South Korean hospitals who underwent optical coherence tomography for evaluation of very late DES thrombosis were retrospectively included in analyses. VLST occurred at a median of 55 ...
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  Mentions: Gary S. Mintz University of Ulsan Yonsei University
13. Coronary Plaque Characteristics Associated With Reduced TIMI (Thrombolysis in Myocardial Infarction) Flow Grade in Patients With ST-Segment–Elevation Myocardial Infarction A Combined Optical Coherence Tomography and Intravascular Ultrasound Study
  
  Explore Circulation Sep 14 2016 Cardiology
  
  Background Previous studies reported that reduced TIMI (Thrombolysis in Myocardial Infarction) flow grade before procedure was associated with worse clinical outcomes in patients with ST-segmentelevation myocardial infarction undergoing primary percutaneous coronary intervention. The aim of this study was to identify specific morphological characteristics of the culprit plaque associated with poor TIMI flow grade at baseline in patients with ST-segmentelevation myocardial infarction using both optical coherence tomography and intravascular ultrasound. Methods ...
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  Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University
14. Coronary Plaque Characteristics Associated With Reduced TIMI (Thrombolysis in Myocardial Infarction) Flow Grade in Patients With ST-Segment–Elevation Myocardial Infarction A Combined Optical Coherence Tomography and Intravascular Ultrasound Study
  
  Explore Circulation Sep 1 2016 Cardiology
  
  Background Previous studies reported that reduced TIMI (Thrombolysis in Myocardial Infarction) flow grade before procedure was associated with worse clinical outcomes in patients with ST-segmentelevation myocardial infarction undergoing primary percutaneous coronary intervention. The aim of this study was to identify specific morphological characteristics of the culprit plaque associated with poor TIMI flow grade at baseline in patients with ST-segmentelevation myocardial infarction using both optical coherence tomography and intravascular ultrasound. Methods ...
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  Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University
15. Change of retinal pigment epithelial atrophy after anti-vascular endothelial growth factor treatment in exudative age-related macular degeneration
  
  Explore Indian Journal of Ophthalmology (IJO) Aug 1 2016 Ophthalmology
  
  ...pital, Kyung Hee University, Seoul, Korea Correspondence Address: Seung-Young Yu Department of Ophthalmology, Kyung Hee University Hospital, Kyung Hee University, Seoul Korea Source of Support: None, Conflict of Interest...
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  Mentions: Kyung Hee University
16. Associations between the Framingham Risk Score and coronary plaque characteristics as assessed by three-vessel optical coherence tomography
  
  Explore LWW Online May 25 2016 Cardiology
  
  Objectives: This study sought to explore the association between the Framingham Risk Score (FRS) and coronary plaque characteristics assessed by optical coherence tomography (OCT) imaging. Background: Clinical prediction models are useful for identifying high-risk patients. However, coronary events often occur in individuals estimated to be at low risk. Methods: A total of 254 patients with coronary artery disease who underwent three-vessel OCT were divided into tertiles according to FRS. Nonculprit ...
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  Mentions: Massachusetts General Hospital Ik-Kyung Jang Harvard University
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