1. Kyoto University Graduate School of Medicine

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    1. Mentioned In 176 Articles

    2. Optical coherence tomography in coronary atherosclerosis assessment and intervention

      Optical coherence tomography in coronary atherosclerosis assessment and intervention
      Since optical coherence tomography (OCT) was first performed in humans two decades ago, this imaging modality has been widely adopted in research on coronary atherosclerosis and adopted clinically for the optimization of percutaneous coronary intervention. In the past 10 years, substantial advances have been made in the understanding of in vivo vascular biology using OCT. Identification by OCT of culprit plaque pathology could potentially lead to a major shift in ...
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    3. Wide Field Choroidal Thickness of Eyes with Central Serous Chorioretinopathy Examined by Swept-Source Optical Coherence Tomography

      Wide Field Choroidal Thickness of Eyes with Central Serous Chorioretinopathy Examined by Swept-Source Optical Coherence Tomography
      Purpose: To examine widefield (WF) changes in the choroidal thickness of eyes with central serous chorioretinopathy (CSC). Design: An observational study. Participants: Twenty-two patients with treatment nave unilateral CSC (20 men and two women) and 28 normal eyes of 28 age-matched healthy participants (21 men and seven women). Methods: We performed enhanced depth imaging (EDI) of swept-source optical coherence tomography (SS-OCT) with a viewing angle of vertical 20 mm horizontal ...
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    4. The intercapillary space spectrum as a marker of diabetic retinopathy severity on optical coherence tomography angiography

      The intercapillary space spectrum as a marker of diabetic retinopathy severity on optical coherence tomography angiography
      Microcirculatory disturbance plays a pivotal role in the pathogenesis in diabetic retinopathy (DR). We retrospectively quantified the total counts and morphological features of intercapillary spaces, i.e., intercapillary areas and nonperfusion areas (NPAs), on swept-source optical coherence tomography angiography (SS-OCTA) images and to evaluate their associations with DR severity grades. We acquired 3 3 mm OCTA images in 75 eyes of 62 diabetic patients and 22 eyes of 22 nondiabetic ...
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    5. Unilateral transient high myopization after pediatric strabismus surgery: Observation by anterior segment optical coherence tomography

      Unilateral transient high myopization after pediatric strabismus surgery: Observation by anterior segment optical coherence tomography
      Purpose: To describe an unusual case of unilateral transient high myopization after pediatric strabismus surgery. Observations: A 6-year-old girl with intermittent exotropia had undergone strabismus surgery and experienced a transient decrease in best-corrected visual acuity (BCVA, from 20/20 to 20/33) with high myopization (from +0.25 D to -9.00 D). Slit-lamp microscopy showed anterior chamber inflammation and a narrow angle only in the affected eye. Anterior segment ...
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    6. Peripheral Chorioretinal Imaging Through a Front Prism on Optical Coherence Tomography Angiography

      Peripheral Chorioretinal Imaging Through a Front Prism on Optical Coherence Tomography Angiography
      Purpose: To evaluate the clinical feasibility of peripheral chorioretinal imaging through a front prism on swept-source optical coherence tomography angiography (SS-OCTA). Methods: We prospectively obtained en face OCTA images using SS-OCTA in 10 eyes of 10 healthy volunteers. For the peripheral chorioretinal imaging, the scanning laser passed and refracted through a 45-90-45 right-angle prism. We evaluated the qualitative and quantitative characteristics of chorioretinal vessels in the periphery. Results: Using peripheral ...
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    7. Longitudinal changes in complete avascular area assessed using anterior segmental optical coherence tomography angiography in filtering trabeculectomy bleb

      Longitudinal changes in complete avascular area assessed using anterior segmental optical coherence tomography angiography in filtering trabeculectomy bleb
      Optical coherence tomography angiography (OCTA) is a new technique for non-invasive imaging of blood vessels, allowing combined evaluation of both deep and surface vessels. The purpose of this study was to evaluate the post-trabeculectomy longitudinal changes in complete avascular area (CAA) of filtering blebs using anterior segment (AS-) OCTA and their association with surgical outcomes. This study included 57 eyes of 53 patients who had undergone trabeculectomy with mitomycin C ...
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    8. Improved accuracy of tissue glucose measurement using low magnification optical coherence tomography

      Improved accuracy of tissue glucose measurement using low magnification optical coherence tomography
      Optical coherence tomography (OCT) has a comparatively high spatial resolution among tomographic bioimaging techniques and is less affected by changes in physiological conditions such as temperature, blood pressure, and osmolytes in the tissue. OCT detects changes in the refractive index of tissues, which is a function of the tissue glucose concentration (TGC). OCT signal intensity generally decreases with tissue depth, and its slope is expected to show a negative correlation ...
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    9. Correlations among age, sex, axial length, and subfoveal choroidal thickness in the choriocapillaris structure analyzed using multiple en face image averaging optical coherence tomography angiography

      Correlations among age, sex, axial length, and subfoveal choroidal thickness in the choriocapillaris structure analyzed using multiple en face image averaging optical coherence tomography angiography
      ...ained from all the participating subjects. In this prospective, cross-sectional study, data were collected at Kyoto University (Kyoto, Japan) and Kagawa University (Kagawa, Japan) from October 2017 to April 2019. All the...
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    10. Prevention of Image Quality Degradation in Wider Field Optical Coherence Tomography Angiography Images Via Image Averaging

      Prevention of Image Quality Degradation in Wider Field Optical Coherence Tomography Angiography Images Via Image Averaging
      Purpose: Assessment of cardiovascular risk is the keystone of prevention in cardiovascular disease. The objective of this pilot study was to estimate the cardiovascular risk score (American Hospital Association [AHA] risk score, Syntax risk, and SCORE risk score) with machine learning (ML) model based on retinal vascular quantitative parameters. Methods: We proposed supervised ML algorithm to predict cardiovascular parameters in patients with cardiovascular diseases treated in Dijon University Hospital using ...
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    11. Human Foveal Cone and Müller Cells Examined by Adaptive Optics Optical Coherence Tomography

      Human Foveal Cone and Müller Cells Examined by Adaptive Optics Optical Coherence Tomography
      Purpose: The purpose of this study was to image and investigate the foveal microstructure of human cone and Mller cells using adaptive optics-optical coherence tomography. Methods: Six healthy subjects underwent the prototype adaptive optics-optical coherence tomography imaging, which allowed an axial resolution of 3.4 m and a transverse resolution of approximately 3 m. The morphological features of the individual retinal cells observed in the foveola were qualitatively and quantitatively ...
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    12. Prediction of trabecular meshwork-targeted micro-invasive glaucoma surgery outcomes using anterior segment OCT angiography

      Prediction of trabecular meshwork-targeted micro-invasive glaucoma surgery outcomes using anterior segment OCT angiography
      We performed a prospective, longitudinal study to investigate the association between the preoperative intrascleral vasculature assessed using anterior segment (AS)-optical coherence tomography angiography (OCTA) and surgical outcomes of trabecular meshwork-targeted micro- or minimally invasive glaucoma surgery (MIGS). We included 37 patients with primary open-angle glaucoma. Preoperative AS-OCTA images of the sclero-conjunctiva of the nasal corneal limbus were acquired in the superficial (conjunctival) and deep (intrascleral) layers. The vessel densities ...
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    13. Detection Sensitivity of Retinitis Pigmentosa Progression Using Static Perimetry and Optical Coherence Tomography

      Detection Sensitivity of Retinitis Pigmentosa Progression Using Static Perimetry and Optical Coherence Tomography
      Purpose: To compare the detection sensitivities of the progression of retinitis pigmentosa (RP) by automated perimetry to obtain the mean deviation (MD) and total point score and by optical coherence tomography (OCT) to determine the residual ellipsoid zone (EZ) length and thickness of retinal layers. Methods: Twenty-two eyes of 22 patients with RP who underwent annual automated perimetry (Humphrey Field Analyzer 10-2) and OCT examinations during the same period more ...
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    14. Successful Treatment of Post-Phacoemulsification Descemet’s Membrane Detachment Assessed by Anterior Segment Optical Coherence Tomography: A Case Report

      Successful Treatment of Post-Phacoemulsification Descemet’s Membrane Detachment Assessed by Anterior Segment Optical Coherence Tomography: A Case Report
      ...tocol for this retrospective study was approved by the Institutional Review Board and Ethics Committee of the Kyoto University Graduate School of Medicine (approval number R2652). All clinical procedures were conducted a...
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    15. Image Evaluation Of Artificial Intelligence Supported Optical Coherence Tomography Angiography Imaging Using OCT-HS100 Device In Diabetic Retinopathy

      Image Evaluation Of Artificial Intelligence Supported Optical Coherence Tomography Angiography Imaging Using OCT-HS100 Device In Diabetic Retinopathy
      Purpose: To investigate the effect of denoise processing by artificial intelligence (AI) on the optical coherence tomography angiography (OCTA) images in eyes with retinal lesions. Methods: Prospective, observational, cross-sectional study. OCTA imaging of a 3 x 3 mm area involving the lesions (neovascularization, intraretinal microvascular abnormality, and non-perfusion area) was performed five times using OCT-HS100 (Canon, Tokyo, Japan). We acquired AI-denoised OCTA images and averaging OCTA images generated from five ...
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    16. Short-Term Effects of Different Types of Anti-Glaucoma Eyedrop on the Sclero-Conjunctival Vasculature Assessed Using Anterior Segment OCTA in Normal Human Eyes: A Pilot Study

      Short-Term Effects of Different Types of Anti-Glaucoma Eyedrop on the Sclero-Conjunctival Vasculature Assessed Using Anterior Segment OCTA in Normal Human Eyes: A Pilot Study
      Background: To investigate the short-term effects of different types of anti-glaucoma eyedrop on sclero-conjunctival vasculatures and their associations with intraocular pressure (IOP) reduction. Methods: This was a prospective study including 20 healthy subjects. A single instillation of ripasudil or bimatoprost was introduced into the right eyes of the participants. The superficial (conjunctival) and deep (intrascleral) vasculatures of the corneal limbus using anterior-segment optical coherence tomography angiography (OCTA) and IOP were ...
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  2. About Kyoto University Graduate School of Medicine

    Kyoto University Graduate School of Medicine

    Kyoto University is a major national university in Kyoto, Japan. It is the second oldest university in Japan, and formerly one of the Imperial Universities of Japan. The university has a total of about 22,000 students enrolled in its undergraduate and graduate programs.  Kyoto University has historically advocated a "spirit of freedom" in its academic activities. Kyoto University Graduate School of Medicine is a medical school associated with Kyoto University.