1. Kyoto University Graduate School of Medicine

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    1. Mentioned In 141 Articles

    2. Segmentation of the Four-Layered Retinal Vasculature Using High-Resolution Optical Coherence Tomography Angiography Reveals the Microcirculation Unit

      Segmentation of the Four-Layered Retinal Vasculature Using High-Resolution Optical Coherence Tomography Angiography Reveals the Microcirculation Unit
      Purpose : To differentiate the four layers of the retinal vessel network in the human macula and examine their morphologic features using high-resolution optical coherence tomography angiography (HR-OCTA). Methods : Macular areas measuring 464 464 pixels of 10 right eyes of 10 healthy subjects without ocular disease were scanned 10 times using a HR-OCTA device. Averaged OCTA images were created. Based on clear decorrelation signals, four vascular slabs were segmented, comprising one ...
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    3. Direct comparison of optical coherence tomography and high-definition 60-MHz intravascular ultrasound imaging of intra-procedural stent thrombosis in a patient with acute coronary syndrome

      Direct comparison of optical coherence tomography and high-definition 60-MHz intravascular ultrasound imaging of intra-procedural stent thrombosis in a patient with acute coronary syndrome
      An 80-year-old man with ST-segment elevation myocardial infraction underwent coronary stenting using an everolimus-eluting stent, which resulted in a good coronary flow with no residual stenosis. However, 10 min after final coronary angiography, the patient complained of chest discomfort and the ECG again showed ST elevation. Repeat coronary angiography revealed multiple contrast filling defects in the stent. High-definition 60-MHz intravascular ultrasound (IVUS) examination showed multiple low echoic structures inside the ...
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    4. Anterior Segment Optical Coherence Tomography Angiography in a Patient With Persistent Pupillary Membrane

      Anterior Segment Optical Coherence Tomography Angiography in a Patient With Persistent Pupillary Membrane
      The image depicts a 60-year-old woman with bilateral cataracts and no history of amblyopia, strabismus, or systemic diseases. Color slitlamp photography of the left eye ( Figure , A) showed a persistent pupillary membrane, with multiple iris strands extending from collarette to collarette and adhering to the anterior lens surface. Anterior segment optical coherence tomography angiography ( Figure , B) showed vessels originating from the lesser arterial circle of the iris and anastomosing with ...
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    5. Visualization of the Lamina Cribrosa Microvasculature in Normal and Glaucomatous Eyes: A Swept-source Optical Coherence Tomography Angiography Study

      Visualization of the Lamina Cribrosa Microvasculature in Normal and Glaucomatous Eyes: A Swept-source Optical Coherence Tomography Angiography Study
      Purpose: The purpose of this study was to investigate the lamina cribrosa (LC) microvasculature using swept-source (SS) optical coherence tomography angiography (OCTA) images that have been processed using multiple image averaging and a projection-resolved algorithm. OCTA has recently gained popularity for assessing retinal and choroidal microvasculature . However, it is not known if the LC microvasculature , which likely holds important information for further understanding of glaucoma , can be visualized with OCTA ...
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    6. Optical coherence tomography for observation of the olfactory epithelium in mice

      Optical coherence tomography for observation of the olfactory epithelium in mice
      Objective Optical coherence tomography (OCT) is an imaging tool that exploits the coherence of infrared light and is clinically utilized in the field of ophthalmology and dermatology. This study aimed to examine the feasibility of using OCT for diagnosing degeneration and regeneration of the olfactory epithelium in mice. Methods The olfactory and respiratory epithelia in excised nasal septa of adult mice were observed using OCT. Subsequently, histological assessments were performed ...
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    7. Swept-Source Optical Coherence Tomography Angiography of Microaneurysms in Myopic Retinoschisis

      Swept-Source Optical Coherence Tomography Angiography of Microaneurysms in Myopic Retinoschisis
      A woman in her early 30s presented with floaters that had been present for several years. Her best-corrected visual acuity was 1.5 (20/13) OU. Axial length was 27.93 mm OD and 27.35 mm OS. Numerous aneurysms were observed temporal to the macula, predominantly in the left eye ( Figure , A). Swept-source optical coherence tomography angiography confirmed that these aneurysms were located in the retinoschisis cavity ( Figure , B ...
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    8. Pilot study assessing the structural changes in posttrabecular aqueous humor outflow pathway after trabecular meshwork surgery using swept-source optical coherence tomography

      Pilot study assessing the structural changes in posttrabecular aqueous humor outflow pathway after trabecular meshwork surgery using swept-source optical coherence tomography
      This study evaluated the morphological change in aqueous humor outflow (AHO) pathways using swept-source optical coherence tomography (SS-OCT) volumetric scans in glaucoma patients before and after glaucoma surgery. In this prospective observational case series, 15 eyes (13 patients) with glaucoma were treated with 120-degree Trabectome or 360-degree suture trabeculotomy and followed up for 3 months. B-scan images of the posttrabecular AHO pathway were reconstructed and the pathway areas were evaluated ...
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    9. Deep-Layer Microvasculature Dropout by Optical Coherence Tomography Angiography and Microstructure of Parapapillary Atrophy

      Deep-Layer Microvasculature Dropout by Optical Coherence Tomography Angiography and Microstructure of Parapapillary Atrophy
      Purpose : To investigate the association between the microstructure of -zone parapapillary atrophy (PPA) and parapapillary deep-layer microvasculature dropout assessed by optical coherence tomography angiography (OCT-A). Methods : Thirty-seven eyes with PPA devoid of the Bruch's membrane (BM) (PPA) ranging between completely absent and discontinuous BM were matched by severity of the visual field (VF) damage with 37 eyes with fully intact BM (PPA +BM ) based on the spectral-domain (SD) OCT ...
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    10. The Association Between Macula and ONH Optical Coherence Tomography Angiography (OCT-A) Vessel Densities in Glaucoma, Glaucoma Suspect, and Healthy Eyes

      The Association Between Macula and ONH Optical Coherence Tomography Angiography (OCT-A) Vessel Densities in Glaucoma, Glaucoma Suspect, and Healthy Eyes
      Purpose: To evaluate strength of associations between optical coherence tomography (OCT)-angiography vessel density (VD) measurements in the macula and peripapillary region of the optic nerve head (ONH) with standard structural OCT thickness measures. Materials and Methods: This cross-sectional study included 333 eyes of 219 primary open-angle glaucoma patients, 41 glaucoma suspects, and 73 healthy participants from the Diagnostic Innovations in Glaucoma Study (DIGS) with good quality OCT angiography images ...
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    11. EVALUATION OF MACULAR ISCHEMIA IN EYES WITH BRANCH RETINAL VEIN OCCLUSION: An Optical Coherence Tomography Angiography Study

      EVALUATION OF MACULAR ISCHEMIA IN EYES WITH BRANCH RETINAL VEIN OCCLUSION: An Optical Coherence Tomography Angiography Study
      Purpose: To quantitatively assess macular morphology and perfusion status using optical coherence tomography, and optical coherence tomography angiography in eyes with branch retinal vein occlusion when macular edema has completely resolved, and to investigate the impact on visual function. Methods: Thirty consecutive eyes with branch retinal vein occlusionmacular edema that resolved after treatment with intravitreal ranibizumab injections were included. Macular sensitivity was measured by microperimetry; defect length of foveal ellipsoid ...
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    12. Choriocapillaris flow deficit in Bietti crystalline dystrophy detected using optical coherence tomography angiography

      Choriocapillaris flow deficit in Bietti crystalline dystrophy detected using optical coherence tomography angiography
      Background/Aims This study aimed to evaluate blood flow in the choriocapillaris in patients with Bietti crystalline dystrophy (BCD) with CYP4V2 mutations using optical coherence tomography angiography (OCTA), and to explore the parameters associated with visual function. Methods This prospective case-series study included 13 eyes of 13 consecutive patients with BCD with CYP4V2 mutations and 20 healthy eyes. Using OCTA, we obtained en face images of blood flow in the ...
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    13. MACULAR ATROPHY FINDINGS BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY COMPARED WITH FUNDUS AUTOFLUORESCENCE IN TREATED EXUDATIVE AGE-RELATED MACULAR DEGENERATION

      MACULAR ATROPHY FINDINGS BY OPTICAL COHERENCE TOMOGRAPHY ANGIOGRAPHY COMPARED WITH FUNDUS AUTOFLUORESCENCE IN TREATED EXUDATIVE AGE-RELATED MACULAR DEGENERATION
      Purpose: To compare the areas of choriocapillaris (CC) nonperfusion and macular atrophy (MA) in treated exudative age-related macular degeneration. Methods: This was a prospective, observational, cross-sectional study. Forty-four eyes exhibiting MA (42 patients with age-related macular degeneration), with a dry macula, underwent fundus autofluorescence and optical coherence tomography angiography. The area of MA detected by fundus autofluorescence and CC nonperfusion detected by optical coherence tomography angiography was measured using image ...
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    14. Diabetic Neuroglial Changes in the Superficial and Deep Nonperfused Areas on Optical Coherence Tomography Angiography

      Diabetic Neuroglial Changes in the Superficial and Deep Nonperfused Areas on Optical Coherence Tomography Angiography
      Purpose : To evaluate the relationship between lamellar capillary nonperfusion on optical coherence tomography angiography (OCTA) images and neuroglial changes on structural optical coherence tomography (OCT) images in diabetic retinopathy (DR). Methods : We retrospectively reviewed 101 consecutive eyes of 69 patients with DR. OCTA and OCT images within a 3 3-mm square centered on the fovea were acquired simultaneously. The nonperfused areas (NPAs) in the superficial capillary layer (sNPA) (from the ...
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  2. About Kyoto University Graduate School of Medicine

    Kyoto University Graduate School of Medicine

    Kyoto University is a major national university in Kyoto, Japan. It is the second oldest university in Japan, and formerly one of the Imperial Universities of Japan. The university has a total of about 22,000 students enrolled in its undergraduate and graduate programs.  Kyoto University has historically advocated a "spirit of freedom" in its academic activities. Kyoto University Graduate School of Medicine is a medical school associated with Kyoto University.