1. Korea Advanced Institute of Science and Technology

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    1. Mentioned In 28 Articles

    2. All-fiber wavelength swept ring laser based on Fabry-Perot filter for optical frequency domain imaging

      All-fiber wavelength swept ring laser based on  Fabry-Perot filter for optical frequency domain  imaging
      ...spital and Harvard Medical School, Boston, Massachusetts 02114, USA ^2Department of Mechanical Engineering, KAIST, 291 Daehak-ro, Yuseong-gu, Daejeon 305-701, South Korea ^3Harvard-MIT Division of Health Sciences and...
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    3. Feature Of The Week 8/31/14: Fully Integrated High-speed Intravascular OCT/NIRF Structural/Molecular Imaging In Vivo using a Clinically-available NIRF Emitting Indocyanine Green to Detect Inflamed Lipid-rich Atheromata in Coronary-sized Vessels

      Feature Of The Week 8/31/14: Fully Integrated High-speed Intravascular OCT/NIRF Structural/Molecular Imaging In Vivo using a Clinically-available NIRF Emitting Indocyanine Green to Detect Inflamed Lipid-rich Atheromata in Coronary-sized Vessels

      In current study, we fully integrated near-infrared fluorescence (NIRF) molecular imaging into intravascular OCT structural imaging. The OCT/NIRF single catheter imaging clearly demonstrated the microstructure of atheromata and simultaneously identified ICG-enhancing macrophage abundant lipid-rich areas of the plaques. Ex vivo NIRF imaging evidently validated in vivo OCT-NIRF imaging. NIRF signals on ex vivo fluorescence reflectance imaging colocalized well with in vivo NIRF imaging. In vitro ICG cell uptake, correlative fluorescence microscopy, and histopathology corroborated the in vivo imaging findings. Herein, our research team have solved the issues critical for application of this OCT/NIRF imaging technology to clinical practice ...

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    4. Parallel guidance endoscopic optical coherence tomography system for internal diagnosis through active cannulas

      Parallel guidance endoscopic optical coherence tomography system for internal diagnosis through active cannulas

      A parallel guidance endoscopic optical coherence tomography (OCT) system is proposed for minimally invasive internal inspection of inner organs or complex structures for diagnosis. The system is maneuvered to access the target using an active cannulas’ steerable structures. The integration of a specially designed linkage device with the developed system allows the OCT endoscope to scan with enhanced signal-collective performance, while maintaining its tip at a constant distance from the target, as well as expanding the scanning range. The proposed system is integrated with flexible active cannulas, and this prototype is used for testing. The test results show that the ...

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    5. Fully Integrated High-Speed Intravascular OCT/NIRF Structural/Molecular Imaging In Vivo Using a Clinically Available Near-Infrared Fluorescence–Emitting Indocyanine Green to Detect Inflamed Lipid-Rich Atheromata in Coronary-Sized Vessels

      Fully Integrated High-Speed Intravascular OCT/NIRF Structural/Molecular Imaging In Vivo Using a Clinically Available Near-Infrared Fluorescence–Emitting Indocyanine Green to Detect Inflamed Lipid-Rich Atheromata in Coronary-Sized Vessels
      ...Engineering, KAIST, 335 Gwahangno, Yuseong-gu, Daejeon 305–701, Republic of Korea. E-mail: woh1{at}kaist.ac.kr 1. ↵* Dr S. Lee, M.W. Lee, and H.S. Cho contributed equally to this work. 2. ↵† Drs Kim, Yoo, an...
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    6. Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging

      Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging

      Polarization mode dispersion (PMD) has been recognized as a significant barrier to sensitive and reproducible birefringence measurements with fiber-based, polarization-sensitive optical coherence tomography systems. Here, we present a signal processing strategy that reconstructs the local retardation robustly in the presence of system PMD. The algorithm uses a spectral binning approach to limit the detrimental impact of system PMD and benefits from the final averaging of the PMD-corrected retardation vectors of the spectral bins. The algorithm was validated with numerical simulations and experimental measurements of a rubber phantom. When applied to the imaging of human cadaveric coronary arteries, the algorithm was ...

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    7. High-speed automatic segmentation of intravascular stent struts in optical coherence tomography images

      High-speed automatic segmentation of intravascular stent struts in optical coherence tomography images

      Recently, Optical Coherence Tomography (OCT) has become one of the preferred clinical techniques for intracoronary diagnostic imaging. Thanks to its high resolution imaging capability, the OCT technique allows to identify microscopic features associated with various types of coronary plaque and to track of stent position, malaposition and neo-intimal tissue growth after stent implantation. Accurate visualization of stent struts can help to examine the status of implanted stents potentially leading to proper treatment of the coronary artery disease. However, unfortunately, current stent identification involves time-consuming segmentation algorithms sometimes requiring labor-intensive manual analysis process. To resolve the problem, we propose a high-speed ...

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    8. Feature Of The Week 3/3/13: Complex wavefront shaping for optimal depth-selective focusing in optical coherence tomography

      Feature Of The Week 3/3/13: Complex wavefront shaping for optimal depth-selective focusing in optical coherence tomography
      ...n vivo applications in the near future. For more information see recent Article . Courtesy YongKeun Park from Korea Advanced Institute of Science and Technology . We present that a novel wavefront shaping approach improv...
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  2. About Korea Advanced Institute of Science and Technology

    Korea Advanced Institute of Science and Technology

    Korea Advanced Institute of Science and Technology (KAIST) was established in 1971 as the nation’s first graduate school specializing in science and engineering education and research. The school’s founding was a catalyst for Korea’s rapid rise from a producer of light industry goods to a world leader in high-technology industries.