1. Korea Advanced Institute of Science and Technology

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    1. Mentioned In 26 Articles

    2. Parallel guidance endoscopic optical coherence tomography system for internal diagnosis through active cannulas

      Parallel guidance endoscopic optical coherence tomography system for internal diagnosis through active cannulas

      A parallel guidance endoscopic optical coherence tomography (OCT) system is proposed for minimally invasive internal inspection of inner organs or complex structures for diagnosis. The system is maneuvered to access the target using an active cannulas’ steerable structures. The integration of a specially designed linkage device with the developed system allows the OCT endoscope to scan with enhanced signal-collective performance, while maintaining its tip at a constant distance from the target, as well as expanding the scanning range. The proposed system is integrated with flexible active cannulas, and this prototype is used for testing. The test results show that the ...

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    3. Fully Integrated High-Speed Intravascular OCT/NIRF Structural/Molecular Imaging In Vivo Using a Clinically Available Near-Infrared Fluorescence–Emitting Indocyanine Green to Detect Inflamed Lipid-Rich Atheromata in Coronary-Sized Vessels

      Fully Integrated High-Speed Intravascular OCT/NIRF Structural/Molecular Imaging In Vivo Using a Clinically Available Near-Infrared Fluorescence–Emitting Indocyanine Green to Detect Inflamed Lipid-Rich Atheromata in Coronary-Sized Vessels
      ...Engineering, KAIST, 335 Gwahangno, Yuseong-gu, Daejeon 305–701, Republic of Korea. E-mail: woh1{at}kaist.ac.kr 1. ↵* Dr S. Lee, M.W. Lee, and H.S. Cho contributed equally to this work. 2. ↵† Drs Kim, Yoo, an...
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    4. Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging

      Spectral binning for mitigation of polarization mode dispersion artifacts in catheter-based optical frequency domain imaging

      Polarization mode dispersion (PMD) has been recognized as a significant barrier to sensitive and reproducible birefringence measurements with fiber-based, polarization-sensitive optical coherence tomography systems. Here, we present a signal processing strategy that reconstructs the local retardation robustly in the presence of system PMD. The algorithm uses a spectral binning approach to limit the detrimental impact of system PMD and benefits from the final averaging of the PMD-corrected retardation vectors of the spectral bins. The algorithm was validated with numerical simulations and experimental measurements of a rubber phantom. When applied to the imaging of human cadaveric coronary arteries, the algorithm was ...

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    5. High-speed automatic segmentation of intravascular stent struts in optical coherence tomography images

      High-speed automatic segmentation of intravascular stent struts in optical coherence tomography images

      Recently, Optical Coherence Tomography (OCT) has become one of the preferred clinical techniques for intracoronary diagnostic imaging. Thanks to its high resolution imaging capability, the OCT technique allows to identify microscopic features associated with various types of coronary plaque and to track of stent position, malaposition and neo-intimal tissue growth after stent implantation. Accurate visualization of stent struts can help to examine the status of implanted stents potentially leading to proper treatment of the coronary artery disease. However, unfortunately, current stent identification involves time-consuming segmentation algorithms sometimes requiring labor-intensive manual analysis process. To resolve the problem, we propose a high-speed ...

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    6. Feature Of The Week 3/3/13: Complex wavefront shaping for optimal depth-selective focusing in optical coherence tomography

      Feature Of The Week 3/3/13: Complex wavefront shaping for optimal depth-selective focusing in optical coherence tomography
      ...n vivo applications in the near future. For more information see recent Article . Courtesy YongKeun Park from Korea Advanced Institute of Science and Technology . We present that a novel wavefront shaping approach improv...
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    7. Polarization sensitive full-field optical coherence tomography based on bi-stable polarizaton switch

      Polarization sensitive full-field optical coherence tomography based on bi-stable polarizaton switch

      We present polarization-sensitive full-field optical coherence tomography (PS-FF-OCT), which is based on a bi-stable polarization switch (BSPS) device. The proposed PS-FF-OCT is a Linnik type interferometer, and allows getting both the birefringence-induced phase retardation and the intensity images of specimens with high resolutions using a pair of micro objectives and a BSPS device. Two orthogonal polarization states are formed with a regular time interval by the BSPS device that changes the polarization direction of light in a short time by switching its optic axes. Therefore, both the horizontally polarized light signal and the vertically polarized light signal from the sample ...

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    8. Complex wavefront shaping for optimal depth-selective focusing in optical coherence tomography

      Complex wavefront shaping for optimal depth-selective focusing in optical coherence tomography

      We report on an approach to exploit multiple light scattering by shaping the incident wavefront in optical coherence tomography (OCT). Most of the reflected signal from biological tissue consists of multiply scattered light, which is regarded as noise in OCT. A digital mirror device (DMD) is utilized to shape the incident wavefront such that the maximal energy is focused at a specific depth in a highly scattering sample using a coherence-gated reflectance signal as feedback. The proof-of-concept experiment demonstrates that this approach enhances depth-selective focusing in the presence of optical inhomogeneity, and thus extends the penetration depth in spectral domain-OCT ...

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  2. About Korea Advanced Institute of Science and Technology

    Korea Advanced Institute of Science and Technology

    Korea Advanced Institute of Science and Technology (KAIST) was established in 1971 as the nation’s first graduate school specializing in science and engineering education and research. The school’s founding was a catalyst for Korea’s rapid rise from a producer of light industry goods to a world leader in high-technology industries.